FEMARA Reviews (LETROZOLE)

Average Rating: 2.5 (1087 Ratings)

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 HORMONAL BIOLOGICAL RESPONSE MODIFIERS AROMATASE INHIBITORS

 Type: Rx Drug

  

FEMARA  (LETROZOLE):  This medication is used to treat certain types of breast cancer (such as hormone-receptor-positive breast cancer) in women after menopause. Letrozole is also used to help prevent the cancer from returning. Some breast cancers are made to grow faster by a natural hormone called estrogen. Letrozole decreases the amount of estrogen the body makes and helps to slow or reverse the growth of these breast cancers.   FDA Approval Date: 1997-07-25 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR FEMARACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  breast cancer I now have osteoporosis, and arthritis in fingers. Bad joints and right foot very painful. Get depressed, anxious and get terrible hair thinning in the summer. Vaginal dryness, skin rashes always in spring . F 57 3 years
30 mg
3/28/2017
 3  Stage 1 Breast Ca If it wasn't for the fact my feet hurt like hell every time I get up to walk, I'd stick with this, I can tolerate the vaginally dryness, etc, but the foot and leg pain, not tick mention night leg cramps, all dissappear after stopping for a week, I think I'll take my chances. F 63 3 years
15
3/25/2017
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 1  breast cancer left breast grade 1/2 Violent bone pain all over trigger finger vaginal itching drives me mad insomnia weakness itching under breasts and arms numbness. Housebound I call it "my poison" F 72 4 years
2/24/2017
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 1  Fertility This is the worse fertility treatment I've had in my life. I have dizziness, nausea, diarrhea, I pooped on myself in my bed, headaches, neck pain (i had to wear a neck brace for a night) hip joint pain, no appetite, extreme exhaustion, barely can move, shoulder pain leading into my elbow and I am only on day 3 of Taking this medicine. I dont recommend it but everyone reacts different.I am a very healthy person, I never reacted to anything like this before. F 29 5 days
5.0mg
2/5/2017
 2  Breast cancer Nothing for first 2 months then wow felt like I had been crushed, vaginal dryness, difficulty getting out of chair, car, stiffness of muscles, joints oh wow had arithritis to start but joints are burning and I cannot walk all the time. Walking helps after I get my balance etc. To be on this for 10 yrs. If I knew of something that did not have the awful side effects. Do not know if these side effects will continue to get worse. My trigger finger is moving to thumbs now too...... F 78 4 months
2.5 mg 1X day
1/30/2017
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 5  BREAST CANCER Bone, muscle and joint pain...feet, knees, calves, hips, shoulders. Hot flashes (they have subsided significantly). Thinning hair & dry skin Weight gain Yes, there is joint, bone & muscle pain, hot flashes and thinning hair. Ibuprofen helps but what helps most of all is exercise--a double edge sword since exercise helps with the pain, but the pain makes you shudder at the thought of exercising! Understand that many people experience horrible pain, but it is pain you can get used to and being active definitely helps. A little Toppix hair powder helps with the thinning hair. F 55 3 years
2.5 MG 1X day
1/25/2017
 1  hormone related breast cancer Muscle pain in neck,arms and legs.. Upset stomach and nausea, night sweats, depression and anxiety, thinning hair, nerve pain, numbness and tingling all over body. This is the worst pill ever, I took Tamoxifen for 5 years and it was not as bad. I was happy when the 5 years was up only to be told research had suggested another 5 years with letrozole. I have been so miserable and sickly , told my doctor I wanted to stop as I have no quality of life. He has encouraged me to continue, what upsets me is that there is nothing to counteract these horrendous side effects and they just expect you to bear it. Yes we all want to stay cancer free, but surely there is a better way. I had to give up my job. I feel sad that we are having to suffer this way due to this nasty disease. Hopefully they will find a better solution. F 57 2 years
2.5 mg
1/22/2017
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 1  to prevent breast cancer recurrence Severe joint pain in the lower back and hips, then in knees and feet after a year. Eventually couldn't exercise or unable to walk the next day if I did. Unable to continue with sports such as golf or tennis. Carpal tunnel syndrome in both wrists. Weight gain. Developed severe osteoporosis and onc wanted to put me on meds with even greater bone effects. Had completed 5 years of Tamoxifen prior to Femara with moderate side effects of stiffness and weight gain. This drug is toxic and literally sucks the life out of you. Have returned to Tamoxifen for an additional 5 years. Newest literature demonstrates that AIs may not be as superior as once thought. F 59 18 months
20mg 1X day
1/15/2017
 1  stage 1 grade 3 b c severe joint pain thinning hair weight gain tired moody overall sick F 58 5 years
? 1X day
1/3/2017
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 4  Breast cancer stage 1 Sweating, joint pain F 67 3 years
2.5 mg
12/27/2016
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 1  Stage 2 breast cancer, her2positive On the sixth day of taking this poison, the pain in my foot and hip became so intense I was unable to walk. On day 7, I had a stroke affecting my right arm and hand. Was hospitalized. Immediately quit taking the drug. Almost two months have passed and still cannot use my right hand. Physical therapy twice a week, can now wiggle my thumb a little. This has pretty much destroyed my art career. Was not advised by my doctor that this drug can cause strokes and heart attacks. I have a family history of heart disease and stroke, which i stated in my patient info. Should have been on blood thinner, like baby aspirin. At least the horrible pain in my hip and foot has subsided after two months. I can walk now. F 64 7 days
2.5 mg 1X day
12/25/2016
 2  Stage I Breast Cancer severe insomnia Hot flashes Tiredness Please find an alternative. I don't know how Long I can do this F 56 5 months
30 mg
12/4/2016
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 3  Breast Cancer, Stage 2, Grade 3 Everything I've read here in spades. My body temperature increased significantly as soon as I went on it. Within my first 6 weeks of use, I gained 20lbs. Have since gained an additional 10 for a total of 30lbs, and holding. Joint pain was almost unbearable, especially upon waking. Felt like my feet had been bound. Theres more, but it's all been said already. I was ready to shelve this drug at the 1 year mark,a and then side effects became more tolerable 2 weeks shy of that date. Still on it at the 18 month mark. Can not imagine another 8 1/2 years on it, frankly. The latest course of treatment is recommendation for 10 years. Ugh. You'd think they could do better than this, no? F 51 2 years
2.5 MG
11/25/2016
 3  Breast Cancer, Stage 2, Grade 3 Everything I've read here in spades. My body temperature increased significantly as soon as I went on it. Within my first 6 weeks of use, I gained 20lbs. Have since gained an additional 10 for a total of 30lbs, and holding. Joint pain was almost unbearable, especially upon waking. Felt like my feet had been bound. Theres more, but it's all been said already. I was ready to shelve this drug at the 1 year mark,a and then side effects became more tolerable 2 weeks shy of that date. Still on it at the 18 month mark. Can not imagine another 8 1/2 years on it, frankly. The latest course of treatment is recommendation for 10 years. Ugh. You'd think they could do better than this, no? F 51 2 years
2.5 MG
11/25/2016
 3  Breast Cancer, Stage 2, Grade 3 Everything I've read here in spades. My body temperature increased significantly as soon as I went on it. Within my first 6 weeks of use, I gained 20lbs. Have since gained an additional 10 for a total of 30lbs, and holding. Joint pain was almost unbearable, especially upon waking. Felt like my feet had been bound. Theres more, but it's all been said already. I was ready to shelve this drug at the 1 year mark,a and then side effects became more tolerable 2 weeks shy of that date. Still on it at the 18 month mark. Can not imagine another 8 1/2 years on it, frankly. The latest course of treatment is recommendation for 10 years. Ugh. You'd think they could do better than this, no? F 51 2 years
2.5 MG
11/25/2016
 1  Breast cancer stage 2 Horrible, severe pain in the bones and muscles surrounding the whole hip area. Total and painful stiffness during night time with unability to move or go to the toilet. My osteoporosis (due to early menopause) has increased and I have severe problems in my lower back now. I wake up during the night with tharcycardia felt in the ears. This is the most chocking and horrible experience I have ever had. I don't believe it has any good effects at all - and if so it certainly does NOT uplift the side effects. I would strickty recommend not to take it. I only took it for 34 days. I have been off now for almost 2 months and the side effects are still there. This is poison for your body. Don''t ever allow your body to get destroyed by it! Femara should not be allowed to sell or to give to any cancer patient. It is POISON! F 47 1 months
2,5 mg
11/1/2016
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 5  BC Initially no side effects, however I gained weight, which my doctor denies is caused by Femara, some thinning hair, but nothing too severe, a bit foggy The lump in my breast is gone! How good is that? After two years on it, ultrasound couldn't detect any abnormal tissue. F 48 3 years
2.5 1X day
10/5/2016
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 1  breast cancer loss of weight 50 lbs in first 4 years , loss of appetite , panic attacks, constant abdomen pain, Change in lifestyle, stopped shopping, all activities ex. bowling , movies etc, anything with noises. F 78 2 years
1X day
9/2/2016
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 5  Breast Cancer 06/2006 After 5 years of Tamoxifen I was switched to Femara/ Letrozole. The only real side effect was that I was exhausted and had to take a nap daily. This went on for a few months until I acclimated. I just finished my 5 years two weeks ago and once again I am needing daily naps. Extreme fatigue at the start and again now that I am off. My mother was dx with two bc's at age 78 in one beast, but because of age and health she did not do any surgery or anything other invasive treatments. However, she was put on Femara. Now, about 4 years later she shows no indication of either one. The Femara completely obliterated both lumps! F 56 5 years
20mg
7/28/2016
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 5  Breast cancer recurrence Hot flashes and night sweats but bearable. So far no other side effects I'm taking letrozole and Ibrance. After only 6 weeks tumor is shrinking. Feeling fine except for the hot flashes. Please give these drugs a chance. Don't let all the bad reviews scare you. Everyone is different. F 48 5 weeks
2.5
7/6/2016
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