FEMARA Reviews (LETROZOLE)

Average Rating: 2.5 (1087 Ratings)

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 HORMONAL BIOLOGICAL RESPONSE MODIFIERS AROMATASE INHIBITORS

 Type: Rx Drug

  

FEMARA  (LETROZOLE):  This medication is used to treat certain types of breast cancer (such as hormone-receptor-positive breast cancer) in women after menopause. Letrozole is also used to help prevent the cancer from returning. Some breast cancers are made to grow faster by a natural hormone called estrogen. Letrozole decreases the amount of estrogen the body makes and helps to slow or reverse the growth of these breast cancers.   FDA Approval Date: 1997-07-25 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Gender with females listed first (reviews with no gender reported listed before females).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR FEMARACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Stage 3B Breast Cancer I really can't attribute my negative feelings/experiences to anything other than life. I suppose some are from the chemo, radiation & Femara, but am glad to be alive, moving and working. Sometimes my right hip hurts. I was depressed, now taking 300mg Effexor-this has worked wonders. NO weight gain, no more crying or wishing I was dead. I have joined humanity again! Praise God. Bi-lateral mastectomy in 3/06 after 12 yrs of HRT due to total hysterectomy in 11/93. Life goes on, I am thankful things seem to be working out. Femara must being doing something! Just wanted to be an encouragement to those starting out on the drug - not everyone has the awful side-effects mentioned. I did have minor hot-flashes - perhaps the Effexor helped? I lost a lot of aspects of my life due to the cancer. Recently I have forced an exercise regimen by riding my bicycle 14 or 20 miles round trip to work, depending upon the location. This has helped tremendously with my achy neck and right hip. I find that movement is much easier upon wakening. God's Blessings 49 1.5 years
10/9/2007
 4  Prevent BC recurrence Fingers of rt. hand very stiff. Swelling in legs. Hot flashes, osteoporosis & hair loss. My pain isn't severe, but I am concerned about the swelling. I have kids and need to be here for them. The drug appears to be working, so I guess I can cope w/the effects. 3 years
10/8/2006
 4  Stage III breast cancer I experienced severe joint pain, mainly in my right hip, thigh and knee and stiffness in my neck. Upon awakening in the morning and after sitting for any length of time, I walked like I was crippled. My bones in my feet hurt really bad upon getting out of bed in the morning. I had extreme difficulty going up and down stairs, or hills when going for walks. I still experience fatigue and memory issues, but those may be long term post-chemo side effects. I have tried all supplements I can think of; liquid glucosamine, cinnamon, turmeric, over the counter anti-inflammatories, all to no avail. The last time I saw my oncologist (October 2011), I asked if there might be a prescription anti-inflammatory. He prescribed Mobic (Melaxicam) and told me to try it, and if it did not help within 30 days to not refill the prescription. I have had AMAZING relief from the Mobic. I have absolutely NO hip, leg or knee pain. I would say that my pain was so debilitating that I was begging to go off the Femara, but now I will take it for however long he tells me to. I have also been in core strengthening and stretching classes as well as yoga classes and I am sure that has helped. I would suggest at least trying this, knowing that everyone responds differently to this drug. Keep your spirits up, be proud to be a survivor, and make each day a positive experience. 57 22 months
2.5 1X day
12/14/2011
Email
 4  BC stage 1 I took this for 2 years, 9 months. Stopped due to osteoporosis. I did not want to take a biophosphate. I experienced bad foot pain, hip pain and pain in my thumbs but would have stayed on it. Onc switched me to Tamoxifen. My plan is to take this for 2 years, 3 months to finish out my 5 years. Tamoxifen is causing severe anxiety. I hate it. 56 2 years
3/14/2016
 3  Breast cancer Tired, easily depressed, extreme hot flashes and heart palpitations. Migraine aura worsened.Pain in feet, exercise helps. Cannot loose weight. No recurrence (to my knowledge!).Basically the most important, and I am grateful about that,but life has really changed 59 4 years
4/15/2017
 3  recurrant breast cancer Joint aches, hip pain, neuropathy, weight gain,heart palpitations, and did I say joint pain, I mean extreme joint pain. I was on Tamoxifen for 5 yrs, went off and 2 mo. later had a chest wall recurrance, this time had chemo and radiation, and am now on Femara. Was told I would have to be on it for life. Which I hope is a long time. But could just cry sometimes with the pain and discomfort. Would appreciate any suggestions for the pain and wt gain. 57 1 days
4/11/2008
Email
 3  1st stage breast cancer Bad hip pain & stiffness - hard to get up from a chair - going up stairs is a nightmare. I get really sleepy once I sit down to relax after work. I started taking Femara in May 2008 after chemo, radiation, & Herceptin. The hip pain was not too bad at first, but has gotten worse the last few months. There is also a feeling of achiness like the flu. I have tried Tylenol and Motrin, but do not see any difference. I have been taking the Femara in the morning, but I think I am going to try taking it before bed to see if that helps. The hip pain & stiffness is mostly when I try to get out of a sitting position or do the stairs. I push myself to keep going - I work fulltime and have a husband, 2 children, & 4 grandchildren - so I keep busy. Seems I am tired early in the evening, but sometimes when bedtime comes, I am wide awake - go figure. I felt great while having chemo & radiation - not many bad effects. I have spoke to a couple of ladies that are on Femara and they all say the same thing about the joint pain, achiness, & tiredness. They need to make a medicine to counteract the side-effects. I hope th 55 9 months
2/17/2009
 3  yes constipation, osteopenia,hot flashes,colon resection,pain everywhere,heartburn,Lichens sclerosis,hair loss,dry eyes etc.. was on tamoxifen 5 yrs and femara 4 years+ 2 months quit 2 days ago does anyone know if bone loss improves after you go off? 70 4 years
2.5 mg 1X day
12/1/2011
 2  stage 2 a estrogen pos breast ca joint pain, stiffness, difficulty walking at times, hands sore, fatigue, heart palpitations, and higher cholesterol been on this for 2 years following 2 years of tamoxifen and 1 year of another aromatase inhibitor. My onc wants me on this for 2 more years. Feel arthritic, can be hard to walk in the morning, feel clumsy because I keep dropping things. Does this get better after stopping? 51 2 years
7/16/2007
 2  prevent reoccurence joint/bone pain, hair loss, large itchy bunps on neck near back hair line, depression,fatigue. don't know if this medication is working. only been on it for a short time. thinking of going off this drug because of side effects. quality of life issues. can't imagine being on it for 5 years. very worried about bone loss. 64 4 months
11/5/2006
 2  to prevent return of breast cancer WEIGHT GAIN, joint pain, depression, massive sweating once off femara, I dieted off the weight but it seems to creep up more easily now, within a few weeks of stopping the drug my mood returned to happy, sweating subsided and aches and pains went away. 50 3 days
1/20/2006
Email
 2  prevent reoccurence joint/bone pain, hair loss, large itchy bunps on neck near back hair line, depression,fatigue. don't know if this medication is working. only been on it for a short time. thinking of going off this drug because of side effects. quality of life issues. can't imagine being on it for 5 years. very worried about bone loss. 64 4 months
11/5/2006
 2  
11/5/2006
 2  Stage III Metastic IBC severe stiffness and joint pain in ankles/feet. Weight gain. Hot flashes. 50,000 icu Vitamin D, hot spa tub for fee/ankles, requip for RLS, Effexor for hot flashes, STAY ACTIVE! 48 6 months
4/28/2008
Email
 2  Breast Cancer Significant joint pain in feet and other joints including elbows and hands. The worst of all is the joint pain in my jaw, making it hard to chew food. Insane scalp rashes/itching, rashes on arms as well. I hate Femara but my Oncologist insists that if I can tolerate it at all that the benefits outweigh the pain. 59 3 years
8/19/2008
 2  mastectomy stage 0-1 estrogen +Her2 Thumb can't hold a pen ankle pain stiffness throughout legs.insomnia nightly 30lb weight gain lower legs ankles completely swollen I try to exercise need serious motivation as energy is drained from work had mastectomy mammos have since been clear in remaining breast. weight gain is very hard to shed. 61 3 years
2.5mg
1/25/2014
 1  stage 2 breast cancer 1 days
9/22/2014
 1  Stage 1 breast cancer Severe joint pain especially fingers, back, knees. Fatigue,mood changes, sleep problems, I stopped the drug. I have lost myself . I don't feel human anymore. 5 weeks
1X day
1/6/2015
 1  reocurrent breast cancer Extreme pain in both hands with very limited mobility and carpal tunnel-like symdrome in left hand..Awake every morning with claw type hands and pain is constantly there all day.. Swelling in feet and knees with decrease in energy. I was on Tamoxifen for 5 years (with no problems at all) and then on Femara for 6 mos. before going off of it...My doctor feels that there is a definite correlation between the pain and the drug..Have been off of it for almost 5 months now and even with chiropractic care and a physical therapist, have no relief at all. Am worried this could be permanent effect! Novartis, the drug company producing this drug should be accountable for symptoms that just will not go away!! 62 6 months
10/1/2006
Email
 1  Stage 4 BC Hot flashes (internal thermostat broken), hair loss, weepiness, and an insidious development of pains in hips, legs, joints as well as exhaustion and a constant feeling of being overwhelmed. My question is have any other patients had herniated discs after using drug? Please reply... After 8 months, finally realized that physical side effects were from Femara. Within 2 weeks of stopping drug, had 2 herniated discs and I'm wondering if Femara didn't contribute...the aging effect of the drug may have made me susceptability to spinal injury. Please ring in if you've had an experience like this. Thank you and may God bless us all! 59 9 months
2.5 1X day
11/30/2012
Email
  

FEMARA  (LETROZOLE):  This medication is used to treat certain types of breast cancer (such as hormone-receptor-positive breast cancer) in women after menopause. Letrozole is also used to help prevent the cancer from returning. Some breast cancers are made to grow faster by a natural hormone called estrogen. Letrozole decreases the amount of estrogen the body makes and helps to slow or reverse the growth of these breast cancers.   FDA Approval Date: 1997-07-25 (Sources: U.S. Centers for Medicare Services, FDA)

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