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Drug Ratings for FEMARA

Average Rating: 2.5 (940 Ratings)

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    New! Reviews Summary for FEMARA  | Top 10 Adverse Effects (reported to FDA)

RATING  REASONSIDE EFFECTS FOR FEMARACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
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 3  breast cancer Joint and breast pain stiffness F 64 5 years
2.5
8/11/2014

 1  Breast cancer Right away I had terrible back pain.I dismissed the pain thinking it was a pulled muscle.Pain also in joints and breast pain. The worse side effect is a severe rash ,on my neck,face wrists and the breast that was operated on. On steroids now to try and get rid of the rash . Will not take anymore drugs. F 58 2 weeks
2.5mg
8/9/2014
Email
 2  Breast cancer grade 2 mastectomy Vaginal atrophy,joint stiffness, extreme fatigue and tiredness , hot flushes, insomnia Vaginal atrophy almost immediately. Over the last 12 months insomnia ,lethargy,and extreme tiredness. I have lost me! Will continue with the drug at present but it seems to me that the cure is worse than the disease. Feeling quite depressed. Rads no Chemo. F 64 12 months
2.50 1X D
8/6/2014

 2  Hormone positive breast cancer joint, muscle and bone pain, high cholesterol, thinning hair, diarrhea, extreme vaginal atrophy, loss of sex drive, arthythmia, blood clotting issues, extreme stiffness, tiredness, horrible back pain and virtually non-stop hot flashes and night sweats every night, insomnia, anxiety, itching, and breathlessness!!! For me, this drug is a quality of life REDUCER. I do not believe we have sufficient information about FEMARA or other aromatase inhibitors. And I have read many times that FEMARA and other AIs don't enhance life expectancy, mainly due to their contribution to heart problems. So, if the cancer doesn't get you, your heart will ... !!! F 51 3 years
2.5 1X D
8/6/2014
Email
 5  post Ca breast Swollen, painful and stiff fingers and feet, which are worse in the mornings. Dreadful mood swings......I can be so nasty at times to my partner. Palpitations. Cry easily. Poor concentration. Poor memory. Loss of libido. F 54 2 years
30 1X D
7/28/2014
Email
 5  Breast Cancer 2B Insomnia. Mild hot flashes. No sex drive. F 54 1 years
7/25/2014

 1  Breast cancer Really bad hot flashes Headache Painful joints Insomnia F 66 2 weeks
Once a day
7/5/2014

 1  stage l estrogen positive Insominia, hot flashes, chills, nausea, increased blood sugar, increased blood pressure, tired, racing heart and constant pain. Decided to ask doctor to stop taking letrozole. Fingers in both thumbs were in pain. Got a cortizone shot for the left trigger finger but it helped only for one week. Still in pain. F 70 10 days
2.5 1X D
6/26/2014

 1  breast cancer, earl stage gradual worsening of hand stiffness, ankle stiffness, tendonitis thumb, fingers stiff, quality of life going down hill wondering if this medication is making my tendons and joints age fast, am off it for 1 month, considering switching to tamoxifen F 62 2 years
2.5 mg 1X D
6/14/2014

 5  Breast cancer Initially no side effects. after six years I blamed my weight gain on this med. I had become lethargic and down-hearted.Cancer responded well to this and other chemotherapy: cancer numbers receding. Taken off Femara three months ago. Energy level and general disposition are improving. F 68 7 years
30 1X D
6/10/2014
Email
 2  Stage 1 invasive lobular breast ca I started Arimadex 8/2012. Could hardly walk by 12/13. Horrible joint pain and sweating/hot flashes. Wanted to try femara, wanted one of the above to go away. Right away my joint pain was better, and still is better than with arimadex. Still sweating a lot, but not quite as much as with arimadex. But these muscle spasms in my ribs and back are terrible. It spreads across my chest and hurts like crazy. It is beginning to affect my work. My hands are getting stiffer as time goes on. I'm not sure what to do, go back on the other?? Or go back and forth?? Vaginal atrophy is really a problem too. F 59 4 months
2.5 mg 1X D
5/6/2014
Email
 3  to reduce estrogen production Hot flashes, thinning hair, muscle pain, joint stiffness, fatigue, inability to lose weight (although I work out 6 days a week and have reduced my caloric intake), mood changes (depression), difficulty in sleeping through the night. I would really like to stop taking this drug but cannot risk the return of breast cancer. I am trying to convince myself that my mood changes are not due to this drug but am convinced that Femara is the culprit. I was so positive and upbeat before but now I seem to alternate between a constant desire to cry, hide in my house or hit something. BUT I have committed to not giving up or giving in to depresssion - thank God for prayer! The physical exercise does help - especially my 4 mile walks but I'd sure like to see some results from all the working out. I'll be discussing my mood with my Oncologist at next visit though - I can't survive with my mood in the dumps all the time - life is too precious and I want to savor each moment. F 53 9 months
2.5 1X D
4/12/2014
Email
 1  Breast Cancer Stage 1 My side effects were slow in coming but gradually dominated my life to the point that joint pain, lack of quality sleep, depression, paranoia, and lethargy made each day miserable. I used to be the most positive, energetic person I knew. I surely miss the old me. I went off this horror last week and am feeling my energy and personality sneaking back. The debilitating back and neck pain continue, but I am taking my chances here. The cure is worse than the disease. F 62 11 months
1X D
4/2/2014
Email
 2  breast cancer stage 1 grade 3 hair on legs completely stopped growing so will see what happens to my head hair; I have muscle and joint pain never experienced before and it is becoming more severe as my time on this drug grows. Swelling in hands, tired all the time,difficulty sleeping, weight gain; but I think the most distracting and disabling side effect is the body pain and lethargy; I don't feel much better than I did on chemo and raditation, and it has been 3 months since I finished treatments; I expected to feel like "my old self" but I don't. Depression? I am known to be a highly energetic and optimistic person--definitely not so right now... F 60 2 months
2.5 mg dai 1X D
3/26/2014

 3  2A Her2Neu+ Breast Cancer Bone, joint, hip pain & slippage, blurry vision, fatigue/exhaustion, headaches, back pain, bRuTaL nerve pain, ataxia type symptoms (balance & coordination), mood swings, weight gain, night sweats, sleeplessness, disturbingly sweaty...all that stuff! Oww & Yuk! :( Updates on things that might manage side effects. I've mentioned NeoCell for bone pain. I still take the collagen but also take straight Hyaluronic Acid. Please check with your doc & make sure you are NED before taking as HA may increase cell division. For nerve pain/neuropathy I take Redd Nerve Sheild, a mix of B vitamins and cucurmin. Also taking Bellena Nelle Omega 3 for nerve pain. It's widely known for heart health, but you may not know it also helps nerves. No fishy taste, there is lemon taste to it. Taking nascent nano colloidal iodine for breast health and/or take Celtic Sea Salt (watch Dr. Bob de Maria on YouTube for interesting info). Lose inflammatory acid & sugar diet. Some of my exceptions and indulgences: replaced my morning coffee with a homemade tea of Braggs vinegar (a good acid that balances), fresh (micro-planed) ginger, local honey and a dash of black pepper. Ginger is in the cucurmin family and as someone mentioned, you need to add black pepper to bring out the anti inflammatory compounds in the ginger too. Staying hydrated has been mentioned. Watermelon works wonders for me! :) For those of you who have a mean sweet tooth like me, and if you haven't had them in a while, try dates. I forgot how good, sweet & healthful they are. Like many of you, I never know how I am going to feel til I wake up in the a.m. and I am by no means pain free, some days are still brutal, but I feel I am gaining the tools to manage it better. Hang in there & ke F 50 4 years
2.5 1X D
2/11/2014
Email
 1  Infertility Migraines, joint pain, weight gain This med made me feel horrible and I didn't realize it was this drug until recently. I am no longer taking it but continue to have persistent joint pain and†I†had a herniated disc. No baby either. My doctor was shocked I was on it so long and said it was dangerous, asked who prescribed it to me like that and tried to deny it when I said her. Confusing and scary. F 28 3 years
2.5 5X M
2/2/2014
Email
 5  Stage IIIa bc ER+ her2- bilateral Started to gain weight immediately. Have now gained about 10 pounds. Need to stop eating so many sweets. No significant increase in joint or bone pain. Need much more sleep than before even after chemotherapy and radiation about 2 1/2 years ago. Looking back, sleep needs increased after beginning Femara. Also, less optimistic and energized than before. F 53 5 months
1/31/2014

 2  mastectomy stage 0-1 estrogen +Her2 Thumb can't hold a pen ankle pain stiffness throughout legs.insomnia nightly 30lb weight gain lower legs ankles completely swollen I try to exercise need serious motivation as energy is drained from work had mastectomy mammos have since been clear in remaining breast. weight gain is very hard to shed. 61 3 years
2.5mg
1/25/2014

 3  Stage 1 Breast Cancer Joint pain, trigger fingers, major depression, significant hair loss Stage 1 lobular carcinoma: bilateral mastectomy followed by hysterectomy. Tumors (9 of them) were 99% estrogen+. Had carpal tunnel in both hands within a couple of days of beginning letrozole, which has subsided. I've had medication-controlled depression for years, but have been in the worst depressive state since starting letrozole. Working with psychiatrist to try different meds/dosages but the depression hasn't abated at all. I force myself to take 3-5 mile walks four days a week, mostly hoping it will help with the depression. The depression is what may end my usage of letrozole although I'm terrified to stop using. Almost 9 months of crushing depression has left me visiting the suicide websites. I keep reading the same page every day to make it through. The page stresses that suicide happens when pain outweighs resources. For me, that pain is mental; I can tolerate the physical discomfort. I find myself crying every time I read about any kind of suffering in the world (animal, human, etc.). I keep telling myself that this too shall pass. I'm also a three year survivor of Stage 4 thyroid cancer. My hair is half-gone since beginning letrozole. God bless us all and help us to endure. F 56 10 months
2.5 mg 1X D
1/5/2014
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 2  j Breast cancer My white count is already down to 2.9 & I've had to go on antibiotics for bad sinus infection. I wake up with my joints hurting several times a night. All of my finger joints are sticking & I have developed trigger finger in the 3rd finger of my right hand. . The doctor didn't mention these ahead of time & they are listed as "rare" I accidentally found these on a breast cancer forum where almost every woman had trigger finger in at least one finger. This is extremely painful & disabling. I'm already on Celebrex for a back problem & it's not helping. Cortisone did help my fingers but I can't take it on regular basis. I'm going to try Glucosamine. Women on hormone blockers should be told to take vitamins to counter side effects before they occur, as well as extra for bone, joint support and immune system. F 61 3 weeks
30mg
10/21/2013
Email
 1  Endometriosis This is my 2nd review b/c I had side effects I didn't realize were connected to Femara. I got uterine polyps that cause me such severe anemia I was passing out every time I tried to walk. My uterine polyps were considered iatrogenic because they were CAUSED by Femara. So I needed surgery (a hysteroscopy) because of Femara. So yeah, I'd say no to Femara. It made me need surgery and gave me a cancer scare (thankfully the uterine polyps were benign!). But seriously: go check out Femara's offical website and read the side effects CAREFULLY. F 26 14 days
2.5 MG 1X D
10/13/2013
Email
 1  Estrogen Positive Breast Cancer Three weeks into taking the drug I developed the most severe depression, anxiety and mood swings. My oncologist put me on an antidepressant. I suffered from nausea every day. Towards the end of the 4th month, I became short of breath and felt like I was suffocating. After extensive tests, it was determined that I had lost 1/3 heart function. I suffered from the uncommon side effects. Never did have bone and joint pain, but I think the loss of heart function and depression were worse. I have gone off the drug, I will take my chances... F 64 4 months
1X D
10/7/2013

 1  breast Cancer. estrogen pos. Femara has stunt my hair growth! My hair growth has stopped completely. I can barely do anything because of the hot flashes and sweating. I sweat as if someone has thrown a bucket of water on me. I should have been able to lose weight with the extensive sweating but that isn't the case, I actually have gained weight! I have severe lower back pain along with pain in my legs, also pain in my joints of my fingers and toes. I become so stiff when I am not mobile for awhile, but when I am mobile for long periods of time I pay for it with stronger pain. If I stand up after not moving for awhile my feet is in a combination of pain. My feet become stiff, numb, with full achy pain. I have to stand and give myself a but of a headstart to be able to move about I am truly not happy with this drug. I've read all the pros and cons of this drug with my conclusion there are more cons than pros. F 44 6 months
2.5 mg
9/24/2013
Email
 1  Stage 2B breast cancer Severe joint pain especially in my legs. I have developed carpal tunnel syndrome in my right hand, neuropathy started after I ended chemo and started taking Femara. Foot pain is worsening daily. M 56 1 years
2.5 1X D
9/19/2013
Email
 2  Breast Ca/Stage 1, lumpectomy I woke up during the night to excessive urination. It came out in buckets. I've never experienced anything like it ( except to compare it to my water breaking!) I couldn't function without sleep as I was going to have to drive to see my grandson. I stopped taking it. Doc said to wait a week & try Arimidex. I stiffened up to the point of being unable to walk, my joints swelled & I developed painful trigger finger. My blood pressure went dangerously high, even after 3 doses of Inderal. After 3 wks, took a short break. All symptoms went away. Blood pressure came down to normal. Dr. tried Tamoxifen. To my dismay, the trigger finger came back, with very severe joint pains & stiffness in my hands/ feet, knees. I cannot make a fist without fingers getting stuck. So discouraged. Will try the supplement one lady mentioned for lubrication. I just can't function like this for 5 yrs. I have a home to take care of & no one here to help me. There must be something else that doesn't cause such suffering. No one is guaranteed no recurrence of cancer, but mine was only 1.2cm & I really blame the Estrace. Has anyone tried getting ovaries out? I have a long way to go & just feel horrible. I was Est+/pro+. I am half way through with radiation & that is scary enough. God knows what that will do to my body. Prior to diagnosis was on Estrace, which of course was stopped immediately. Considering getting my last remaining ovary out & m F 61 3 days
9/2/2013
Email
 5  Breast cancer - Radiation treatment At first no problems other than insomnia. Now pain in feet when I first get out of bed but passes after I start walking. Sometimes leg pain, shoulder and back pain but Advil relieves the pain. F 56 3 years
2.5
8/25/2013
Email
 1  cancer it may be brain Mets or femara but my mind is going. I cannot reason I am so confused ....it makes me sad to hear all you old women complaining when you have had long lives and I am dying young. I guess wisdom does not come with age F 32 1 days
2
8/3/2013
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 1  Stage 1 bilateral breast cancer Sleeplessness I cannot sleep on this drug after only 5 days. I had the same problem with Arimidex after ten weeks and switched to Femara. I cannot function without sleep and do not want to take sleeping pills! I feel as if I am on Speed. I am thinking of not taking this anymore! F 59 5 days
1X D
7/15/2013

 3  Stage 2 Estrogen Positive Breast Ca My major side effect is depression......really bad. Mood swings that are set off by insignificant things. I have some joint pain, but not really bad. I have had nausea (much like morning sickness) and stomach cramps. No weight gain yet. F 63 2 months
30mg 1X D
7/10/2013

 3  ER+ PR+ HER- Breast Cancer stage o hot flashes,night sweats,arm,shoulder & neck pain every night, fatigue, frequent urination Advil liquid gel 2 tablets helps with the pain. I had dbl mastectomy but no chemo or radiation F 64 7 months
2.5 1X D
6/28/2013
Email
 5  estrogen postive breast cancer Will continue to take Femara the rest of this last year of treatment despite increasing joint stiffness and major bone pain throughout my body enough to affect my daily life. Often have to take major pain meds to sleep. Take megadoses of D2 for pain weekly + daily doses of D3, calcium and magnesium. Major balding on back of head & vaginal atrophy. Beats another tumor! It is doing what it is supposed to. Clean 4 yrs out. You have to battle breast cancer. It is what it is. F 61 4 years
2.5 mg 1X D
5/22/2013

 1  Breast cancer stage IIB Fatigue, back pain, depression, hot flashes, weight gain around middle, joint pain Started 1 month following last chemo treatment. Fatigue from chemo did not get any better, and depression worsened the longer I took Femara. Severe back pain every day to the point of needing to take Aleve every day to function. I've always been very thin, but noticeable weight gain in the abdominal area. I decided to stop taking Femara for a week to see if I felt any different. BIG improvement - couldn't believe how much better I felt. Fatigue and depression resolved, back pain lessened considerably. Stayed off for almost two months, but oncologist insisted I try Tamoxifen. Am trying it, but will stop if the severe side effects return. It's not worth it to feel so badly all the time. F 56 11 months
2.5 1X D
5/21/2013

 5  Stage 2 BC, ER+ Had the joint pain and hot flashes. Took two two-week breaks in the first year just to get relief from pain. After second break, pain did not recur. The rest of my 5 years went by easily. I did have some bone loss, but had excellent bone health before starting Femara so I never had to do more than take a ton of calcium and Vit. D. Also, no head hair loss, but legs and arms became baby-bottom smooth from loss of hair on them. Since I've gone off it, I've noticed that a heart arrhythmia that was driving me crazy had suddenly gone back to its normal (before femara) once-in-a-while schedule rather than all the time. Hot flashes are worse, than when I was on femara. Not noticed any body hair regrowth, which is kind of nice. F 66 5 years
2,5 mg 1X D
5/7/2013

 2  breast cancer severe joint pain, depression, hot flashes. loss of energy, whole body aching I have been on letrozole for 1 year and it is horrible. I can hardly get out of a chair, walk, sleep, (thank god for ambien and oxy), can't bend my hands hardly walk. no energy to do anything with friends and I usually cancel. the only thing that has helped me is seeing a pain management doctor who has helped me lessen the pain so that I can atleast party live my life. Also, water aerobics is the only thing that I can do and forget about my pain for an hour. TRY IT, IT really works. I am afraid to go off for I never had chemo and stats were based on talking the Femara. My life is a mess. I thought that once you go off the side affects go away and now I am a afraid that is thisl is going to be my life. A cannot work for I cant sit, walk for long times or do anything for more than an hour...I am afraid of eventually will be living on the street. F 50 352 days
1X D
4/30/2013
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 3  Breast Cancer Trigger thumb, weight gain, fatigue, sleeplessness,dizzy at times, low stamina. Arthitis, twisted fingers. Does anyone know if the weight gain goes away after stopping Femara? I have gained 30 pounds since beginning my treatment. F 61 3 years
2.5mg 1X D
4/19/2013
Email
 3  2A Her2Neu+ Breast Cancer This is an update to my 8/11 post regarding debilitating bone pain, particularly in the foot, ankles and hips and my use of NeoCell brand collagen supplements. As an update to my post on my 08/?/2011 the next page over I mentioned taking NeoCell Collagen Type 1&3. I immediately felt fantastic but I noticed after several months of using it seemed to have had sort of a plateau effect. That being said, I had also became very inconsistent in using it as directed...on an empty stomach at the same time every day and sometimes forgetting to take for several days in a row. My bad. I still felt better but "stuck". It got worse when I purchased a different brand and just became miserable all over again. Fast forward and I re-invested in the NeoCell brand. This time I re-researched and purchased the Type 2 Collagen. This is specifically for bones and joint lubrication and contains hyaluronic acid. I've been on it two weeks and feel even better than the type 1 & 3 made me feel. I am also very diligent to take it as directed, on an empty stomach, immediately upon awakening every single day. After approximately 30 minutes, you are then able to take type 1 & 3. They are not to be taken together! I am using type 2 till I run out to gauge the results at which point I plan on taking the two together at the specified time intervals. The pains that I do feel now are more in line with what I felt before femara and for a woman my age and weight (I'm a big girl!). I feel "normal" again. I will update this in a few months but in the mean time, the best price seems to be directly thru NeoCell or thru Amazon. I have not seen i F 49 3 years
2.5 1X D
4/8/2013

 4  ER+ PR+ and Her2+ Breast Ca Mostly hotflashes, some joint pain....I take it at night and then take my sleeping pill so I can sleep through most of it.... F 62 2.5 years
2.5 mg 1X D
4/7/2013

 5  stage 4 recurrence of ER+/PR+ BC Multiple tumors shrank & disappeared after 6 months of drug use. Side effects included joint pain & sleeplessness, which improved after taking glucosamine/chondroitin. 2 years in got bad trigger thumbs, which resolved without intervention in 3 months. Sleeplessness has gone away; now just need more sleep (9-10 hours). After 3 1/2 years, tumors have not recurred. I consider the price paid well worth it. F 65 3.5 years
2.5 mg 1X D
4/4/2013
Email
 1  breast cancer stage 1 I am off of femara since 2011. I am now suffering with vertebra problems in the lumbar spine at many levels (l1-s1) F 66 5 years
3/20/2013

 2  Infertility While only taking for only 5 days a month, I've had bad knee, hip and thigh pain, terrible headaches and heart palpitations also hot flushes. Only on my second month still no baby! F 28 5 days
2.5mg
3/17/2013
Email
 4  BC stage2 lymph nodes clear grade 3 trigger finger, arthritis like symptoms entire body, 2 spells over last 4.5 yrs of low back pain, and recently severe itching around my neck at onset of hot flashes Repost from 3-7-10 - still cancer free at 4 yrs 8 mos - if femara is the reason then the little bit of discomfort I have had is worth it...no doubt, proper nutrition and exercise have helped me immensely...my onc is now suggesting I stay on it another 5 yrs as studies are coming in that 10 yrs use keeps the Big C at bay...I say sign me up for another bottle of femara!!! F 54 4.5 years
2.5 mg 1X D
2/19/2013
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 1  Post op BSO.Past history breast Ca I am reposting having been off this drug for 5 months now. Whilst on it my joints and muscles ached immensely, some days I struggled to walk, get out of the car and walk up stairs. I have been left with excrutiatingly painful feet and heels which has now been Dx by a pain specialist as idiopathic peripheral neuropathy. I have not been able to become pain free following the side effect pains brought on by this horrid poison. F 49 2 months
1X D
2/15/2013
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 1  BREAST CANCER STAGE 2 Estrogen Receptor Positive followed by a complete Hysterectomy. Have been off for 4 yrs on May 27, 2013 and it saddens me that this is not any better for anyone. A lot of the symptoms posted just on page one of 15 internet pages. Most seriously Bones, Joints, Muscles, Headaches, 4 additional meds a day to try to control HB but did not work. Had been walking 4 miles a day 7 days a week and could not walk a block or hardly up and down the stairs. Hands as in finger nuckles bad. Had braces for hands, knees and feet. I wanted to leave a comment again about two things I take everyday that I found out about in this blog almost 4 yrs ago and wanted to share again. Always research and read first and show to your doctor. NATURES WAY KRILL OIL, 500mgs and I take two a day. Herebs of Gold - PAIN EASE I maintain enough with just one a day and of course I take 800mgs of prescribed Ibuprofen twice a day. On top of all this I have severe issues with my back. In the search engine type in Herbs of Gold Pain Ease and read about it. Next type in http://www.proteinpower.com/drmike/inflammation/why-krill-oil/ and read the article from Dr. Michael Eades. It helped the people I found out about it from I am hoping that it will help someone else. Just had my 4 year clear mamo and the tech doing the mamo said there are a lot of women coming in with terrible sideffects of this meds. There may only be 897 ratings but so many don't know about this site. My Hearts best to everyone out there . . . Please feel free to email me anytime, Brenda F 58 4 months
.25 1X D
2/11/2013
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 1  breast ca stage II her2 Joint pain and stiffness in hips, back, and knees, crepey dry skin, thinning hair, ridged nails, cramps in hands, fingers, weight gain from inability to exercise due to joint pain, fatigue. Worsening symptoms of Grave's Disease. It's been almost 6 mths since I stopped Femara, but symptoms haven't abated. Quality of life plummeted. With such compromised mobility I feel like a prisoner as I've formerly been a very active person with many responsibilities. I wonder if my reaction to Femara has something to do with my autoimmune Grave's Disease, i.e. an autoimmune reaction to the anti-estrogen toxin in Femara F 72 9 months
2.5 1X D
2/4/2013
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 4  Breast Cancer Slight hair loss, slight memory loss, irritable, vaginal dryness, slight joint pain. I took Tamoxifen for 5 years and on recommendation of surgeon changed to Femara and was advised that protection of bone density would be less, but less chance of recurring cancer. My 10 years cancer free was March 2011 and am happy that I took the doctor's advice for this 'insurance policy' to now be free of the cancer, and drugs. After nearly 2 years since taking Femara, I am starting to notice a difference - hair growth is back to normal, less vaginal dryness (slowly nearly back to normal), however, joint pain persists and worse as I get older and post-Femara - now take Mobic anti-inflammatory tablets a few days at a time when pain at its worse. F 56 5 years
2.5mg 1X D
2/3/2013
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 3  her2newand estrogen positive stage Bone and joint pain, vaginal dryness, fatigue, memory problems, some weight gain I feel that the bone pain is the worst. However, if it keeps me cancer free it is worth the side effects. My onco wants me on it indefinetly. I hope the side effects don't become worse. It is difficult to exercise. F 58 1 years
2.5 MG 1X D
1/27/2013

 4  Breast Cancer Arthritis, hip pain, weight gain Has anybody else gained weight on Femara? I gain 30 pounds in the last 3 years taking Fermara. The first years was the worst, a lot of pain in hands, feet and could barely stand without pain. Now it has gotten better but I am not really sure why. I will be off of Femara (Letrolzol) in two 1 year 9 months. F 60 3 years
2.5 1X D
1/13/2013
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 3  Breast ca ER+/PR+/HER+ stage2 1st month pretty well, 2nd month wrist pain at time, 3rd mo well tolerated so far with some skin rash had first taken Arimidex, was horrible with joint pain, felt like 100 yrs old, then I had frozen shoulder which was fixed by 2mo therapy. Had to stop after 2mo on it. After 1mo break my onc switched me to Femara with glucosamine and Tumeric 2x/day, It works! F 51 3 months
2.5 1X D
1/2/2013
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 1  Stage 4 BC Hot flashes (internal thermostat broken), hair loss, weepiness, and an insidious development of pains in hips, legs, joints as well as exhaustion and a constant feeling of being overwhelmed. My question is have any other patients had herniated discs after using drug? Please reply... After 8 months, finally realized that physical side effects were from Femara. Within 2 weeks of stopping drug, had 2 herniated discs and I'm wondering if Femara didn't contribute...the aging effect of the drug may have made me susceptability to spinal injury. Please ring in if you've had an experience like this. Thank you and may God bless us all! 59 9 months
2.5 1X D
11/30/2012
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 3  Stage 2 Breast Cancer Sleeplessness. slight frequent headaches, initially dizziness but this has worn off. I have just read all the comments and am now very concerned about what everyone is saying. I will stay on it for now, as I do not want to have to go through this roller coaster ride with cancer again if I can help it. Blessings to all. F 56 3 weeks
1X D
11/19/2012
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 1  Stage IV Endometriosis Bone pain, joint pain, dizziness, blurry vision, excessive vaginal bleeding, and collapsing. I was a healthy 24 year old woman trying it for endometriosis. It crippled me in two weeks. This drug was terrible and I have nothing nice to say about it. I developed uterine polyps and I required surgery. I've dislocated my finger, busted my knee skiing, busted my hip in a car accident, broke my nose, had an earring torn from my earlobe, and had my nostril slit. The pain I felt on Femara mad everything else feel like a tickle. Femara made my bones and joints hurt so bad I was in tears. I cried once in my life because of pain. It was on Femara. Also it didn't work for my endometriosis and I need surgery for the polyps it caused. I give it a negative 100 stars. F 24 14 days
2.5 1X D
11/17/2012

 1  Stage 1 Breast Cancer Femara/ letrozole - I feel like Iím 100 years old. ---I have unbelievable aching, horrible cramping and stiffness in my joints, thighs, hips and legs; my legs and bones literally ache and it gets worse the longer I take this poison. The heels of my feet are killing me. It's extremely difficult, especially after sitting for awhile or when I first get up in the morning, itís a struggle going up and down stairs. --- Change in hair texture and Iím shedding like Angora cat. --- Dizziness Ė Femara related, Iím not sure; but never had it before taking Femara. --- This is not me, Iím extremely lethargic, no motivation, exhausted, can't focus or remember things, donít want to be around people, I donít return phone calls or emails; I hate feeling like this. --- Osteoporosis Ė my doctor wanted me to start Boniva because Femara has a history of sucking the calcium out of your bones. I refuse to take Boniva, like this drug, too many ugl --- I quit taking Femara today (October 27,2012), almost 6 months to the day. My doctor wants to me start on Tamoxifen, which she says doesnít have all these side effects and doesnít require me to be on Boniva....we'll see. Iím checking this site for Tamoxifen and will post my comments in 6 months regarding this drug too. I will give it a try and weigh the side effects; I will quit all these drugs and take my chances if they impact my quality of life like Femara/letrozole. --- Joint, leg cramping/pains, as one review recommended, I started taking Glucosamine (1500 mg) and Chondroitin (1200 mg) around Aug. 18th I donít see any relief. --- Change in hair texture - Two weeks ago, I started using ďJust Natural Organic Hair Care Ė Vinegar Nutritive Rinse CleanserĒ and it's been helping a lot, I really like this stuff. (www.justnaturalskincare.com) F 63 6 months
2.5 mg. 1X D
10/27/2012

 4  Breast cancer Though having joint pain this drug at least helps me to survive F 50 3 years
2.5mg
10/21/2012

 1  Breast cancer Terrible hot flushes, joint pain, sleeplessness, crying, ageing, tiredness. Lost use of ring finger on right hand and rest of fingers and thumbs affected and very painful. Mornings are the worst. Was meant to be on it for five years only lasted five months. F 64 5 months
2.5 1X D
10/13/2012
Email
 4  stage 2 breast cancer Had started with femara four years ago. Switched to generic letrozole. Wake up stiff in morning. By time I get downstairs stiffness gone. Stiff when I get up from chair. Excessive weight gain but my tumid markers have gone down. Hopefully this medication will prevent reoccurence. F 59
2.5mg 1X D
10/8/2012
Email
 3  Endomtrial Stromal Sarcoma Stage 2b Stiffness, joint and bone pain. Burning sensation in hands and feet. High cholesterol, high blood calcium level. Hot/cold flashes and night sweats. Dry skin, change in hair texture. Dizziness. Loss of appetite. Fatigue. The first three months on Femara the only side effects were hot/cold flashes, night sweats, loss of appetite and dizziness. At the three month mark the joint and bone pain started and has some days been very painful. I also found out I now have high cholesterol and high calcium. I read an article the other day that says if a patient takes Femara and experiences new hot flashes and night sweats along with joint pain within the first three months of taking Femara that their cancer is less likely to recur. I sure hope that's correct and the benefits out way the risks. Will reevaluate at the 6 month mark if I want to stay on this drug. F 50 4 months
2.5 mg 1X D
10/7/2012
Email
 1  Breast Cancer Stage II Dibilating join and bone pain. I struggled everyday with stiffness and pain throughout my body; and sleeplessness. It effected my ability to work and perform daily functions. This also resulted in a diagnosis of viginal atrophy. In June I was taken off this drug, since then the pain has gotten worse and I have been diagnosed with Rheumatoid Arthritis. I am not a complainer so I tolerated taking this drug, not knowing that the benefit was miniscule. If I had been given all the stats I would have opted not to take Femara. I welcome any advice on how to relieve the joint pain. the warnings about Femara and Letrozole are inadequate. Warnings should include the statistics on the miniscule benefit of taking this drug vs the long term damage to your body and health. An emphasis needs to be made on the high percentage of women suffering with the long term effects of this drug. F 56 5 years
2.5mg 1X D
9/27/2012
Email
 2  Fertility Issues Ever since I started Femara I haven't been feeling well. I've had really bad abdominal and vaginal pain. I've also had hair loss, upset stomach, acne, and hot flashes. I don't think I will take this medication again. It's made me feel horrible. F 23 5 days
1X D
9/22/2012
Email
 3  Breast Cancer Stage1 been taking this pill for 4 years and 9 months - suppose to take for another 3 months - but i cannot do it - i am so beat up with this pill - i just can't take another day with it - hope everyone has better luck with the side effects than i have had with it. have had pain in joints - horrible pain in stomach - and list goes on. F 68 4 years
2.5 1X D
9/15/2012
Email
 1  Breast cancer Depression lump in throat joy flashes night sweats joint pain tired F 59 4 months
2,5
9/11/2012

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