There are 500 ratings for the drug: PROVIGIL in the Askapatient database.

Key to ratings for provigil: 5-Very Satisfied: this medicine cured me or helped me a great deal. 4-Satisfied: this medicine helped. 3-Somewhat Satisfied: this medicine helped somewhat. 2-Not Satisfied: this medicine did not work to my satisfaction. 1-Dissatisfied: I would not recommend taking this medicine.

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Rating	Reason	Side Effects	Comments	Sex	Age	Time Taken and Dosage		Date Added
				F  M
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1	Stroke related sleep apnea	Hallucinations, extreme sleeplessness, restless, overactive imagination	This was prescribed for my aged father after a stroke - to "pump him up" for rehab, etc. This med caused hallucinations, repeatedly, and caused him to lose sleep and his imaginaton was "out of this world." As we began to wean him off this med, he could not sleep at all, for days on end. After the med was out of his system, the hallucinations and restless subsided or went away completely.	M	77	2 months		5/23/2008 Email
5	Fibromyalgia	Fatigue, brain fog, depression and lack of energy.	Because I am super sensitive to almost all drugs, I take half a tablet (smallest prescribed dosage) when the brain fog and fatigue become exceptionally bad between the times I get injections for the pain. Provigil allows me to feel alert, energetic and non-depressed. If I take it several days in a row, I find it difficult to get to sleep. Other than that, I have no side effects at all. It is a great medication for me.	F	70	2 years		12/5/2008
5	narcolepsy	I have many "side effects but of what I'm not certain as I take a laundry list of medicines. Also, provigil does not remove the side effects of narcolepsy. It does allow me to be awake and with the help of an excellent sleep neurologist I'm gaining a faster wake-up, energy and drive. The provigil is the key to getting there. Incidentally, I use Alertec from Canada, manufactured under license, as it is considerably cheaper and is the same.	I had to use it regularly for some time until I had the desired effect. I don't believe it's a "I need to stay up late tonight" drug. For me it's a miracle drug as I did not want to rely on amphetamines or ritalin.	M	70	3.5 years		4/9/2007 Email
1	hypersomnolence	severe dyskinesia - jaw clenching and teeth grinding	very erratic results at 100 and 200 mg doses. Most of the time it did not seem to affect my sleepiness; once I was "wired"for 36 hours. The dyskinesia never let up.	F	69	14 days		9/13/2007
5	mild ADD	Insomnia if take it too late in morning.	I take about 1/3 of a 200mg. pill, 4 to 5 days/wk. Excellent for organizing paperwork and multiple tasks. Price is prohibitive. Website:canadarxconnection.com lists much lower prices & I will try it when my samples run out.	F	68	2 months		10/24/2004
4	Narcolepsy diagnosis	I am not certain...but it seems I get less done in my life...only the absolutes that are recquired! I can only take 200mg's once a day...and I must say it is the best in the morning. I used to fall asleep at work every day...couldn't sit through even the most stimulating seminar without drifting off. I can't even remember why I didn't like taking more, but I didn't. Now I rely on caffeine pills in the afternoon!		F	66	2 years		3/30/2005 Email
5	chronic fatigue syndrome	It sometimes keeps me awake longer but not always.	I have been taking provigil for about 5 years...it gave me a life! Unfortunately it hasn't made me want to stop eating but I can plan to do something and actually do it. I'm taking 150 mg tab in am.or 1/2 am and 1/2 around 1 pm it doesn't last all day. Around 2 or 3 in afternoon, I'm done.	F	65	5 years		11/28/2009
4	Obstructive sleep apnea	mouth ulcers, very sore tongue, metallic taste, change in smells, some difficulty swallowing	Had more energy in the day time. It definitely helped. However, due to side effects, am not taking it now. Was taking 200 mg per day for about 6 weeks. Will try smaller doses and/or not taking it every day after side effects wear off.	F	65	45 days		7/23/2008 Email
1	narcolepsy	Severe red rash with hive-like bumps on legs and arms that lasted for a month. Skin on legs turned purple red in certain areas. Left leg swelled. Skin peeled as red bumps subsided. I have become intolerant to heat and have perfuse sweating. Capillaries on lower legs have become more permeable which cause some veins to dilate and I have to wear support socks. My narcolepsy has gotten worse and I am totally exhausted most of the time.	I have never had such a severe reaction to any drug in my entire life. To me Provigil is like taking poison. It may have even permanently damaged my hypothalamus and what else?	M	65	25 days		7/13/2007
5	horrible fatigue from Crohn's	None.	I have adrenal supression problems because I have been on Prednisone for Crohn's disease for over 20 years. Without Provigil I am almost tied down to my bed because I have zilch energy to do anything. It to me is certainly a morning medication because if taken too late, staying up all night may be the result. I take 100 or 200 mg almost daily. If I am planning to read and rest, I skip it.	F	64	4 years		1/29/2007
5	narcolepsy	Compulsion to push tongue against lower teeth, causing soreness. Slight loss of appetite. Somewhat depressed libido.	I am taking 200 mg for mild narcoleptic seizures. I didn't actually fall asleep, but felt weird several times a day. These have been 95% eliminated, and I never feel drowsy during the workday. It seems to have an anti-depressant effect too. When I first started taking it, I had a compulsion to clean and organize the house, but that wore off.	M	64	7 months		11/21/2006 Email
5	Fatigue related to sleep apnea	Bruxism (grinding teeth), motormouth	Provigil is outstanding if taken correctly. I take 100mg on awakening in the morning and 50-100mg at noon - none after that. 32 years of type 1 insulin dependent diabetes has resulted in constant fatigue and occasional depression for which I use Lexapro 10mg once daily which also causes drowsiness. Last May, my doctor prescribed Provigil. The first two months produced pure euphoria to the point that I looked forward to getting up early in the morning to take it. I gained so much energy and ambition that I built an addition on my house. I am disabled/retired due to diabetes. To avoid insomnia, I don't take Provigil after noon and since it has only a 6 hour half-life, it's at a low level by night. I take 0.25 mg (1/2 tab) of clonazepam before bed for restless leg syndrome (developed many years before taking Provigil) and sleep like a baby. The euphoria is long gone and I'm taking a larger dose than when I started due to some tolerance developing. On occasion, I will stop taking it for 4-5 days without withdrawal symptoms just to clear my system. Bruxism has always been a problem for me and Provigil has made it worse. On Provigil vs. Nuvigil. Provigil will become generic next year and, by making an inconsequential change in chemistry, the blood suckers created a new prescription drug, Nuvigil that will fill their coffers for the next seven years. When Provigil goes generic, buy it instead of Nuvigil and save $.	M	64	10 months 100 mg 2X D		2/12/2010
4	to avoid day time sleeping			M	64	21 days		5/18/2002
4	Meripex makes me sleepy			F	64			6/21/2007
5	excessive daytime sleepiness, fatig	Mild headaches, slight nausea, tense jaw, dry/swollen eyes with large doses	Has been a godsend, but PLEASE - YOU people who have posted about getting a rash while on Provigil - TELL YOUR DOCTOR. In rare cases this rash can be a serious problem. It is not a panacea - taking it too regularly diminishes the effects; you can build up tolerance; I find if I drink even a little bit of alcohol it dulls me much faster than if not taking provigil. Make sure you drink lots of water, stretch out, relax your jaw. Try taking the smallest dose you need at the time, then increase if you have to. Like others, I find it has changed my life positively - can do more work, stay awake while driving or in presentations/meetings - GREAT for museums where you tend to get tired!	M	63	6 years		1/22/2009 Email
5	To counter side effects of Cymbalta	I take the maximum dosage,200 mg tablets X 2 daily. Only one, and I didn't realize it might be a side effect until I read other entries on this site: the VERY occasional front lobe headache that quickly goes away with asparin.	The drug I have to take, Cymbalta, leaves me overwhelmingly sleepy. I literally couldn't function w/out Proviil. Recently, the Thurs. before the MLK birthday long weekend. I ran out and, through a snafu, couldn't refill untl Tues. I slept, off and on, both day and night, through the long weekend.	M	63	86 months		1/25/2009
3	excessive sleepiness	My ears have felt stopped up and loss of hearing, but not sure if it is from modalert (provigil) would like to know if anyone else has had this symptom while taking it. I took it for three months before symptoms were bad. other than that, no side effects and it helps me stay awake	it is very expensive and my insurance would not cover it because I had not had enough sleep studies done, so I use generic, modalert by mail	F	63	3 months		8/30/2006 Email
2	sleep apnea with daytime fatigue	I started at 200mg for 2 days then cut back to 50mg for 3 weeks. Now on 100mg at 6:30am. Pain and cramping in legs which is getting worse. Increased difficulty in falling asleep due to overall muscle pain. This has increased daytime fatigue, sore eyes and sleepiness. I am in a total brain fog.	I would rate this at 1 but it may be the best drug for some people. That is not for me to decide. This expensive treatment has been a total failure.	F	63	34 days		11/13/2009
5	fatigue from depression and apnea	none, so far	I did not sense any changes until at the end of the day. Then I realized I had not needed a nap, and five waiting projects had gotten done! Very transparent action with no feeling of speeding as had happened before with Ritalin. I also felt cheerier than I was used to. Am also taking 80 mg. of Paxil.	M	62	6 days		2/15/2005 Email
5	Daytime drowsiness	Strong urine odor; some anxiety. But it works so well, and has improved my life so much, the benefits far outweigh the negative side effects. The anxiety actually helps me make the day so much more productive.	I only take it when I know I will be sitting in long and boring meetings, or when I know I have to keep especially alert while working on a project that involves a lot of reading. 200 mg seems to do it, sometimes 400 is needed. For me, I have to classify it as a "miracle drug."	M	62	3 months		6/18/2006
1	ADD	Difficulty starting urination, maintaining the stream and fully voiding. Got worse the longer I took the Provigil. Stopped for 6 months, tried again with same results. Problem is, the side effect persisted even after finally stopping Provigil for good.	Did not warn me of possible side effect, though drug company knew of it. Very upset about that.	M	62	5 months		8/2/2005 Email
5	lifelong daytime drowsiness	For the first few months on Provigil I experienced flu-like symptoms - aches and chills - doctor said it was common, and gradually they went away. If I take too much, I can get a little shaky, but not anxious. Like others, my urine seems darker and stronger-smelling. The most annoying side effect is that I clench my jaws to the point of headaches sometimes, AND - this is the worst - I compulsively push my tongue against the back of my lower teeth so that after awhile my tongue and gums are sore; I've even gotten irritation sores on my tongue. Even though I'm aware of it, I can't stop it. My dentist doesn't think I'm hurting my teeth, anyway. And it's bearable.	Before Provigil, driving any long distance was agony because I had to fight drowsiness so often. (A sleep test said I have "fragmented sleep" but found no cause.)Now I'm totally alert, and the drug is amazing in that I can stay alert and interested through boring lectures and meetings; I contribute and perform much better. (I wish I had had it in college!) I read somewhere that it can make antidepressants more effective (I take Paxil and trazodone) and I really believe it: sometimes if I'm feeling down, I take Provigil for that purpose, it really helps. Interestingly, the drug seems to create a tolerance very quickly - if I take it for several days in a row, I have to increase the dose quite a bit; if I'm trying to work late in the evening, it seems that even taking more Provigil after dinner doesn't really keep me up much later. So I try not to use it every day, and that brings back its potency quickly. I take anywhere from zero to 100 mg to 200 mg and very occasionally mor	M	61	4 times		11/14/2006 Email
5	side effect of tegretol	I have to take tegretol for trigeminal neuralgia, it makes the excruciating pain go away, but it makes me so sleepy. I end up sleeping all the time. Provigil has totally cured that with no side effects at all. I take 100 mg in the morning with my morning tegretol. No provigil with my evening tegretol. No trouble sleeping.		F	61	5 days		3/2/2009
5	daytime sleepiness	Mild headache, jaw and tongue tension, eyes sometimes feel swollen and tender	As others say, it has changed my life. No more am I a dangerously sleepy driver. I can be alert and engaged in meetings, and not fall asleep in lectures. Motivates me for writing and other activities, but I find if I take it in the evening, it's mostly ineffective and just causes discomfort. Can usually sleep when I want to. A great drug. Works best if not taken every day - otherwise some dependence and it becomes less effective.	M	61	4 years		9/13/2007 Email
5	Mild narcolepsy, ADHD, Major depres	Very mild headache.	Began with 200 mg/day which kept me alert until 4 in the morning! Now at 100 mg which works better. Cannot determine whether following side effects are from Provigil or Lamictal, which I take off-label for depression and which I began taking at same time: short temper in evening, slight lightheadedness, cognitive and memory problems. Have definitely felt better emotionally since beginning these 2 medications. Can still fall asleep in front of TV in evening, but that may be the Lamictal.	F	61	2 months		1/8/2008
3	Difficulting getting up	feelings of physical tension	I have insomnia and sleep apnea. Even with a CPAP and doses of Trazodone, Seroquil and klonopin, I still have difficulties going to sleep. I find it hard to get up as a result oif the meds I need to get to sleep and stay asleep. I take 100 mg of Provigil to try and become awake earlier. The doctors keep playing with the dosage and the dosages of my sleep meds to try and get a balance, but haven't found one yet.	M	61	2 months		2/28/2009 Email
3	many years of narcolepsy	Itchy scalp and lots of hair fell out within a couple weeks of starting meds. Increased frequency of headaches.	Although I was alarmed at how much of my hair fell out, Provigil helped me function so much better -- fending off the previously irresistible drowsiness, so I could drive safely, and improved my ability to focus and work productively -- that I felt its good points outweighed the disadvantages. However, when my insurance stopped covering it for a few months, it was so costly that I had to give it up for a while. The withdrawal was exhausting. When coverage resumed, and I restarted the Provigil, a lot more hair fell out and broke off; but, since I needed to function safely, I accepted that loss. When the insurance interrupted coverage again ("doughnut hole" -- a rip-off to discuss in a different forum), once more I had to adjust to life without the meds. So, I've decided to stay off it for now because it's too hard on my system to keep adjusting to the on & off coverage.	F	61	3 years		5/21/2009 Email
5	Excessive Daytime Sleepiness	Mild nervous foot taping, etc. Better sleep.	This drug saved my life. I was sleeping 16-18 hours a day and the doctors could not figure out why. I saw an article on the internet about Provigil and I asked my doctor if I could try it. My employer was planning on putting me on disability the next week. That was over two years ago and I'm still working. I notice that I have a habit of moving my thumb in a cirlce on the TV remote. It drives my wife crazy, but not as much as the constant sleeping did. The only other negative is some mild teeth clenching. I definitely sleep better now that I am taking Provigil. I was diagnosed with sleep apnea, but the pumps didn't help. This did. I take one 200 mg tablet every morning. Before this drug I could not drive more than 15 minutes without being in danger of falling asleep at the wheel. That's all gone. Completely! I have my life back!!!	M	60	2 years		2/21/2007
4	exhaustion depression lethargy	Initially headaches, some dizziness and a slight euphoric feeling, both of which passed within a month or so. Also I cut the dosage in half from 200mgs to 100. I will add that even after cutting back the dose I am still somewhat "edgier" when I'm tense or stressed, which I watch carefully (and the reason I rated this drug a 4 rather than a 5).	I think Provigil has helped me immensely, particularly in relation to my lack of concentration, exhaustion and lethargy. I believe feeling so tired was because of depression, or perhaps a side effect of it. While the Wellbutrin XL along with therapy helped with the depression, I was still somewhat tired a great deal of the time. When I discussed this with my therapist, she suggested Provigil to me and I did some research on it, particularly in combination with an antidepressant. I expressed a concern to her about taking a cocktail of drugs and told her that if I decided to start with Provigil I would start to eliminate the Wellbutrin and she agreed so long as I did not suffer or become depressed again. At first I found the Provigil taken alone at full strength too much for me. I was hyper and even dizzy. So I resumed the Wellbutrin at full dosage, cut back on the Provigil to half dosage and after some months I'm very slowly eliminating Wellbutrin XL in favor of Provigil. But I	F	60	8 months		5/29/2007
2	As supplement to Prozac and CFS	Inital alertness for about 4 hours followed by extreme fatigue along with muscle aches. Although the initial alertness would wear off in 4 hours or so I still would not be able to sleep for days unless I took at least 10 mg (5 times the normal daily dose) of Ativan along with 50 mg. of Seroquil. Sometimes even with 1 Ambien CR 12.5mg added to keep me asleep.	Needless to say I was not alert most of the time (except during that first few hours in the moring when I first took Provigil.) By noon time I was miserable, aching all over, headach, chest pain and feeling anxious. Just a normal dose of a benzo had no effect nor did a commonly perscribed sleeping perscribed pill. Only Seroquil 50mg to 100 mg would ocunteract the terrible physical feeling from Provigil and eventually allow me to sleep.	M	60	5 years 200 mg 1X D		5/17/2010 Email
5	apnea, fatigue, depression	Have had chronic depression for decades and none of the many antidepression medications I tried had any positive effect except for Parnate, an MAOI, whiuch was somewhat effective. I finally stopped taking Parnate to try other avenues. (MAOI with Provigil is considered risky and untested.) Also have sleep apnea and have used CPAP every night for 10 years. Largely side effect free except slight throat irritation which is surprising since my CPAP has an otherwise effective humidifier.	First two days were amazing. Became downright enthusiastic and perky after many months (years, actually) of depression, daytime fatigue, body aches, repetitive yawning, suicidal thoughts, etc. Taking 200 mg in morning. The amazing high subsided over the next ten days to the point where I now feel pretty normal which is a great feeling. I am able to get things done, get out of the house more, interact with people more. I am also motivated to eating healthier which has led to about 5 pounds weight loss in three weeks.	M	59	20 days		6/6/2005
4	MS fatigue	Intense Headaches, migraine type, Pain in right eye and side of face like my migraines. but sometimes no headache!! It's a wonder drug that gets me out of bed and allows me to have a normal day of being productive. I take it when I really have to do something, like go out at night or else I do'nt take it. No other bad side effects except difficult to fall asleep, so I just take 1/2 of the 200 mg pill or 1/4 . BEen taking it for years but very infrequently as stated above. Lately a little more because it does give one energy to exercise, etc.which is important for MS patients and well anyone to do!! Lifts mood a bit, but the headaches when they occur, are bad!!		F	59	100 1X D		2/21/2010
3	Lethargy from MDD	Take 200 mg/day. If I have important event, will increase to 400/day. Severe ringing in ears. No physical cause found. Discovered Provigil as source by accident when I ran out of med. Ringing stopped then started again when med was resumed. Plan to DC if I can find good substitute.	Generally think this is a good med. I have a history of poor sleep before taking Provigil. It helps with energy-just not enough for me.	M	59	3 years		1/16/2006
1	Chronic fatigue	Extremely jittery, horible metallic taste in mouth, heavy chest, nervous	This med made me feel absolutely AWFUL!	F	59	30 days		6/4/2007
1	Sleep Apnea, effected performance	At first, none. About 3 - 4 months in, numbing and tingling of extremeties, toes, esp fingers. Did not see that as a side effect listed? Took 100mg in AM and 100mg after lunch. A week ago 4/24, extreme high fever (thought it was the flu...stopped the Provigil to take night OTC cold meds, thinking it was the flu...) NO congestion though, never had flu been like this?? In two days 4/26, fever had subsided, however, body parts ached like crazy. I went back on Provigil 4/26 not thinking that it could be from it...Sunday, feeling better, but dilerious, not all there, so to speak. Monday 4/27, returned to work, took Provigil as usual, and by the end of the day...zappp, NO VOICE, my larnyx felt like there was someone choking me, laryngitis BIG TIME. Starting to get pretty scared, as there were moments where I felt gagged, I was having difficulty swallowing and at times, I thought breathing...needless to say, I could not sleep the entire night...not a wink...came to this site and saw	It has been three days since being off PROVIGIL, pains in body subsiding, but rash is still there, laryngitis less (I can talk) still feel swelling to the larynx, like something is on it. The fingers feel like they are coming apart at the fingernails..strange, I can still type, but the tips of the index, and middle fingers are numb and tingly, PRAY FOR ME, THAT THIS THING GOES AWAY...IT LITERALLY CAME UPON ME...NO PROBLEMS FOR ABOUT A YEAR, I THOUGHT THE DRUG HAD CHANGED MY LIFE FOR THE GOOD...NOW I WONDER HOW MUCH OF MY INSIDES HAVE BEEN DAMAGED. IF YOU ARE NOT ON THIS DRUG DON'T START; IF YOU ARE GET OFF WHILE YOU CAN!! READ the new FDA Warnings which I had no clue of, read the leaflets that come along with the medicine, then hold on to your throat, YOU MAY BE NEXT... I am not out of the woods yet, everyday thought this withdrawal, something else happens...today I felt swelling of the face and eyes...DOES ANYONE KNOW ABOUT WITHDRAWAL?? I've read no prob to cold turkey...I'll let	M	59	1 years		5/1/2008
5	Sedation/Parkinsons Medication	None	Best medication I've taken for Parkinson's! I felt almost "normal" while using it. My energy level was back to normal, I was clear headed, able to think clearer, and the ability to function normally was fantastic. I also required less Parkiinson's medication. I highly recommend it's use for patients with Parkinson's.	F	58	1 years		9/3/2009 Email
4	fatigue	I exercise an hour daily at the Y and yet I am still very tired especially in the afternoon. I take 100 mg. at around 1 and I have energy through the evening. What is important for me, though, is not to take it daily as I did build up a tolerance. I try to take it 2-3 times a week and never 2 days in a row. It really helps prevent fatigue when driving long distances. I am concerned about LONG TERM side effects and I can not find any studies on this topic.		F	58	2 years		5/26/2007
1	ADD, Lupus fatigue	DANGEROUS!!! Temp. dropped to 95.6, then spiked to 103 in course of an hour. 24 hrs. of severe pain, then a week of weakness.	I took Provigil for a week about a year ago, all fine, but I discontinued due to extreme cost. Still had a few samples left. Took three of them at different times and had severe reaction each time. Ended up in hospital once, very low oxygen saturation, dangerous drop in blood pressure. I thought it was flu and didn't connect it with the Provigil til the third time. Skin rash, aches & fatigue for week or more after each episode. I think it induces major lupus flares for me. BE CAREFUL with this drug.	F	58	7 days		8/31/2008
5	ADD maybe/insomnia daytime problems	None	Works very well for me. I can focus all day, even when I haven't been able to sleep the night before. I can work a full 10-12 hours if necessary, instead of only 4 am to 8 am.	F	57	3 months		1/19/2008
5	Narcolepsy	Mild headaches off and on, take Advil and they're gone. Currently my biggest problem is no desire to do anything! I would be happy just sitting on the sofa and vegitating. Since I can't live my life that way I need to do something about it. Also have some focus problems. And I'm feeling a tad anti-social. Just wanting to withdraw from things.	I must say I like not sleeping all the time. And adore the 20 pounds I've lost. That alone might keep me taking the med! It's curbed my bored eating. Finishing every project I ever started was a nice plus as well, but that side effect went away. it could come back, I liked being productive!! I'm going to try taking half my dosage early in the morning and then the other half in the afternoon and see if that helps with the lethargy.	F	57	5 months		1/21/2008
5	sleeping too much	maybe a little high but nothing else		M	57	1 years		1/1/2009
1	To combat constant tiredness	Headache; sleeplessness; anxiety; crying jags and hopelessness.	This was prescribed by my psychiatrist as a supplement to Prozac which I have been taking for many years, but which has started making me very tired recently. I am not narcoleptic, but I was beginning to need a nap every afternoon. However, when taking this drug I immediately (within days) developed episodes of major depression, started crying hysterically, did not want to live, and felt generally hopeless. Prior to this my mood was always stable if not very optimistic. I immediately stopped taking it and will never touch it again; a day later I already am starting to feel much better.	F	57	1 weeks 100 MG 1X D		2/28/2010 Email
5	narcolepsy	very slight headache at times	It took a lifetime of hearing from doctors that my sleepiness was "normal" until I finally found someone who would listen, a sleep study confirmed narcolepsy, this is one of the few drugs where the side effects are barely noticeable, it has saved my life, literally, because I was having narcolepsy while driving, have never felt wired or other weird feelings while on the drug, I take it daily in the a.m. at 200 mg, no problem now with narcolopsy. I would recommend trying it for narcolepsy.	M	56	6 years		3/10/2007
5	sleep apnea, narcolepsy	Taking 200 mg. Diarrhea; as soon as I eat, I'm off to the bathroom. I am grinding my teeth to the point that I've loosened a cap -- also pushing my tongue down and biting the sides of my mouth and tongue.	Provigil has helped me immensely. Don't fall asleep driving or at work now. More alert. Now if I can just stop grinding and biting!! Any help?	F	56	2 months		1/18/2007
5	multiple sclerosis	none	Saved my life. I suffered from severe fatique. Provigil put the "bounce back in my step". Before taking it, I was losing interest in so many things in life. It has "perked" me up without any nasty side effects. I truely doubt that I would have the quality of life I have today. Without provigil, I doubt if I be as effective at my job (middle school teacher). I take 400 mg a day. I take one pill in am and one at around 2 pm. No problem sleeping-no weight change. A wonder drug!	F	56	4 years		1/16/2007 Email
5	Fibro, Chronic fatigue.	Mild headache, neck stiffness, and jaw clenching. Also digestive discomfort and excess gas.	My rheumatologist prescribed a trial prescription of 200mg tablets. I quickly found out that 200mg is too much for me. Unfortunately, I was coming down with a bad cold the first day I tried it, and didn't sleep for 36 hours. I waited about a week until I was feeling better and split the tablets into 100mg doses. Wow! If this is what "normal" healthy people feel like, I regret feeling miserable for most of my adult life. So far this drug has worked great for me. I'm now getting things done and "almost" enjoying life. The mild headaches have gone away after the first few doses, but the tendency to clench my teeth is still there. The digestive discomfort and excess gas didn't start until I was on the medication for several days. I did not take Provigil today - no gas! We will have to see if this will go away with time. Even if I don't take Provigil everyday, I still seem to experience a boost the day I don't use it. Even considering the side affects, Provigil is extrao	M	56	2 weeks		8/20/2007 Email
5	apathy and fatigue due to depressio	None	200 mg did not work, but once increased to 400 mg a day, it has been very effective. I am more animated and more energetic. My attention span and concentration have improved greatly. I interact with people better and i am able to empathize with them.My attitude is more positive	M	56	6 months		11/6/2007 Email
5	sleeping too much	europia		M	56	3 weeks		8/6/2008
5	severe hypersomnia and depression	HAD VERY SCARY CHESTPAINS, BUT ONLY FOR TWO DAYS. bEEN TAKING NOW FOR THREE MONTHS, BUT HAVE HAD VERY BAD HYPERSALIVATION DEVELOP AND GETTING WORSE.ANYONE KNOW HOW TO DEAL WITH THIS SIDE EFFECT/	wOULD REALLY APPRECIATE IF ANYBODY KNOWS HAS HAD THIS AWFUL HYPERSALIVATION, AND FOUND A CURE FOR IT? (APART FROM STOPPING THE DRUG).it is so helpful in all other ways, and given me a chance to live a normal life again	M	56	3 months		11/16/2009 Email
4	fatigue	none		M	56	2 years		12/10/2003
5	day time sleepiness	I take half a pill a day. A full pill and I can't sleep at all. It has changed my life. I can do things in the evenings that I could never do before. If you take it several days in a row it seems to have diminished effect. I dont know how I got along with out it.	It also seems to keep me in a better mood. I am not jittery like adderal or Ritlin. But I also and not as focused.	M	55	6 months		1/14/2007
5	To help stay alert	None	I work swing shift and was having trouble staying alert while driving home in the morning. I have had no trouble since I started taking Provigil. I only take it 7 times a month while on night runs.	M	55	8 months		9/16/2009
5	chronic fatigue	overeating discontinued, lost all excess weight, depression lifted, calmness prevails, focused, alert, desire to learn	somehow this works better than any antidepressants I have been prescribed (a true lifer) for major depressive disorder. see my psychiatrist regularly. currently not taking any more antidepressants which cause too much lethargy. just taking provigil 200 mg with coffee before work and good to go for all day. normal human being finally after 40 years of chronic fatigue.	F	55	1 years		7/24/2009
5	fatigue	dose dependent spaciness	started taking 100mg 2x day first few days was amazing, after a while I noticed I would get "spacey" and non-productive, and provigil did not have same effect even when increased dose to 200mg 2x/day. So tried 50mg 2x a day and it worked great, now take 50mg 2pm when tired and feel great. There is a "habituation" effect so stop taking it every so often for best results. Also found canadian generic at about $140/200 200mg to save $$	M	55	6 months		10/18/2007
5	Chronic Fatigue Syndrome/Narcolepsy	Headaches.	Absolutely, positively MUST start with a low dose. IF you have a headache -- your dose is too high -- reduce your dose for awhile. With time, I was able to increase my dosage.	F	55	1 years		4/29/2008
3	sleep apnea treatment ineffective	colored urine	Odd how a drug can make you both alert and asleep at the same time. Perhaps it merely wakes me up enough to observe how far south I have gone. Better than nothing for uncorrectable sleep apnea	M	55	4 months		6/14/2008
3	extreme daytime sleepiness	Fatigue, moodiness, muscle pain. Agitation at times. Possibly some paranoia or suspicion.	If you are lactose intolerant, be sure to take Lactaid tabs with Provigil. The formula contains lactose. The jury is still out on Provigil for me: I don't like the psych side effects. It does lift depression but the minute I miss a dose, i feel despondent. I also feel my judgment and caution are off kilter when I take Provigil. As if I am overly-enthusiastic about things. Less prespective than I would normally have.	F	55	30 days		12/17/2009
5	Fibromyalgia and extreme fatigue	Alertness, felt normal for a change, energy level high - first time i took it could not get to sleep, so I take it earlier in the day 200 mg. can't take it daily - have to skip a day here and there. Extreme dry mouth and painful tongue, small price to pay for normal.	Like others, I forgot what normal felt like - love this med, but can't take it all the time; about 3 days and then off for a few or it will "backfire' and I will be exhausted - sleep for 15 hours straight. I couldn't believe the difference it made - me, who would never take even an aspirin!	F	54	8 months		5/24/2008
5	multiple sclerosis	None. Just need to take it about 10-12 hours prior to going to bed.	Love it. It has changed my life. I have been able to resume most activities. I can now stay up and attend evening events. I am able to work 40 hours a week again as an active Realtor. Can not get by without it.	F	54	3 years		1/23/2007
5	Excessive daytime sleepiness.	None.	I work in front of a computer long hours and I was finding I could not stay awake and my job was in jeopardy because of it. My doc put me on Provigil and it is amazing how different my life is. She has suggested I only take on work days as she says it maintains better efficacy if not taken every day. I believe she is right. I seem to tell a greater difference the first day I take it again after not taking it for 2 days. I am taking 300 mg a day on the days I take it, but again try not to take it except when I feel it is going to be absolutely necessary. One thing for sure, it must be taken early in the day, or you will definitely be up for at least the next 12-14 hours after taking it, no matter what time that is! I am very thankful for Provigil and hope that it does not have any long term detrimental side effects that have not been discovered yet.	F	54	3 months		10/9/2004
5	Fibromyalgia / Lupus	Slight headache the first few days of starting the meds. A bit of a euphoric feeling, although not unreal. I think it was the added energy made feel good. I eat less, which is good for me.	I have had fatigue for three years. This drug has saved my life. I have energy again, but not a nervous energy. I want to work, be with my family, begin and complete projects. This is really a revolutionary experience for me. I tried other meds and didn't like the Side Effects. I take 100 mg in the morning around 9 am. This lasts most of the day. I sleep well at night, sleep more soundly than I have in years and wake up ready to go. I also take an nsaid (non-steroid anti-inflammatory) for my muscle pain, but no other drugs.	F	54	1 months		4/23/2007 Email
5	Fatigue and cog problems from MS	The first few weeks I noticed a real buzz. High anxiety and hyper active. It was the most energy I'd felt in years. After the buzz wore off, my life became normal, wich was a great improvement over the constant feelings of lethargy and helplessness I used to feel.	This drug has returned my pre-MS life to me. I can fully function on the job where I had felt (just weeks earlier) that I could not go on any further. It also improved my sleepless nights. I am at high energy (busy and accomplishing things) all day, so I welcome sleep when the time came. 200mg every morning keeps this wake/sleep cycle in balance. Provigil gave me back my life.	M	54	1 years		2/6/2005 Email
4	Severe ADHD	Hard to tell. I was wondering if anyone else had experienced increased joint and muscle pain, but apparently not. I miss my VIOXX. My memory seems less acute.	I find this far more effective, for me, than the standard psychotropics. Most of them were disastrous. I take a hefty dose in the morning, and it's really noticeable by late afternoon if I forget to take it. It makes a big difference to my focus and hence my mood. Without it, I'm incompetent, but this makes me worry a little about dependence. As it wears off in the evening, I become noticeably more fragile.	M	54			10/15/2006
4	Chronic fatigue	EVERYthing has side effects, but if I drink enough coffee to feel reasonably awake, my stomach is a mess. This is like NoDoz without the shakes. I take tiny chips of Provigil only on mornings when I have to be up early for a job or appointment, and I don't recommend taking it every day. When I'm on it, it's the only time I feel OK, except when I'm on vacation 24/7. Otherwise, I'm tired all day, every day. At least with this, I'm only exhausted some days and not others. But yeah, it has drawbacks similar to those of Adderall or any other speed, except that it's not technically addicting and doesn't cause death...that I've heard.	If you have a tendency toward bruxism (tooth-grinding), get a night mouthguard. If it is believed that you have bipolar mood disorder or mania, or a personality disorder, do not take this drug. If you are depressed or chronically fatigued, I recommend this drug on working or busy mornings at critical times only, just to take the edge off the fatigue. Allow your body and brain a weekly or monthly taper-off and cleanout. Use Provigil when it goes generic instead of the more expensive new replacement brand coming out.	F	54	3 months 25-50 mg. 1X D		6/2/2010
4	adult add-cognitive slowing	ringing in ears- initial sleep problems but resolved now as I only take AM-difficulty achieving erection during effective period during the day but OK at night-increased overall sexual desire- desire to smoke to which I succumbed occasionally-initial weight loss but good now	Very effective for me. Helps to stay focused and on task and I am much more alert. I am prescribed 500 mg but usually take around 300 and I find modulating dosage increases effectiveness, taking a day or two off or taking less. Only worry is long term dependence. I've never taken more than prescribed and have no desire to. Not addictive in traditional sense but seems unnatural somehow even though it seems helpful. Very expensive but I prefer not to use other stimulants.	M	54	1 years		4/6/2008 Email
3	ADHD, Predominantly Inattentive Typ	First day smelly urine and slight palpatations	I just added it to my personal cocktail that I take for bipolar ll and anxiety. The complete mix includes, seroquel,lithium lamictal, buspar and now provigil for recently diagnosed adult adhd passive. It has not triggered bipolar cycling nor have there been any drug intereaction issues. I have been able to read the New York Times several days this weeks but I still don't know how effective this will be in the long run.	F	54	13 days		4/28/2008
3	depression, sleepiness	mild headache first few days, intensified depression	The main reason my doctor prescribed Provigil was that I have extreme morning sleepiness and lack of energy. I've been on Cymbalta for over 2 years, but at the dose I tolerate best it doesn't completely relieve the depression. I started Provigil at 1/3 of a 200 mg tablet (approx. 67 mg) for 10 days, and then increased to 1/2 (100 mg) per doctor's instructions. The first two or three days on Provigil I did have increased energy and motivation, and although that faded somewhat after a week or so I did feel more alert. Some nights I had a lot of trouble getting to sleep, and my sleep schedule became erratic because I would stay up very late until I became sleepy. Earlier this week, after having taken Provigil for about 1 month, I became extremely depressed, anxious, and tearful. I didn't link it to Provigil until I read the comments of others who have had a similar experience. I had also noticed that I was talking a lot, which is out of character for me, but I didn't link that to the Provigil, either, until I read other patients' comments. My doctor has taken me off Provigil and increased the Cymbalta. I may try it again at a low dose because I need some relief from the sleepiness/fatigue, which has returned full force.	F	54	1 months		5/2/2009
3	narcolespy	I've been on Provigil for about 2 months 600 mg. I have been experiencing ringing in one ear for about a month. Not sure if this is associated with the provigil, but did not notice this before taking the drug.	My doctor started me off with 200 mg for 3 days; then went to 400 mg for additional 3 days, finally 600 mg daily. The medication seems to work better than Retalin for me,(15 mg 3xday) however, I find that I still get very lethargic after about 4 or 5 hours, if that long. Yawning is presistent. My eyes become droopy (have been asked by others if I'm ok) I'm not necessarily sleepy, but lethargic. Concerned that I'm taking such a high doseage and experiencing these issues. Has anyone else reported ringing in the ears?	F	54	2 months		11/28/2005 Email
3	EDS, Mixed Sleep Apnea, PLMD, r/o N	Prone to tears. Cried once for 4 hours - couldn't stop though nothing was wrong.	Lifesaver for alertness, cognitive abilities restored.	M	54	1.5 months		2/15/2006 Email
3	MS fatigue	Started at 100mg and experienced severe headaches the first 5 days, and some diarhea. By far, the worst is that I'm bipolar and it triggered my first manic episode in 10 years! Didn't mind it the first 2 days. I cleaned everything in sight and started all over again when I was finished. But now I've been manic for 2 days and I'm seriously considering going to the emergency room!!	I haven't taken an afternoon nap since I started Provigil a week ago. Wish I could find a happy medium!	F	54	7 days		9/3/2007
3	chronic fatigue	None whatsoever	This drug may work well for some, but for me, at 200mg a day it was rather diappointing. I could hardly notice any effect at all. I would do just as well by drinking a cup of coffee or taking a caffeine pill. I probably ought to try a higher dose and see if that helps more.	M	54	25 days		3/13/2007
2	Depression low energy	Drugged, jittery, headache, speedy, nauseated, up all night...it took me 2 days to get back to normal	Not for me	F	54	1 days		2/10/2005
1	Excess sleepiness	DO NOT TAKE THIS DRUG! SORRY ABOUT THE "SHOUTING" BY CAPITALIZING BUT THIS REPORT DESERVES IT. I SUFFERED HALLUCINATIONS DUE TO HYPOXIA (LOW OXYGEN TO THE BRAIN), CARDIOGENIC SHOCK, ACUTE KIDNEY FAILURE AND HEART FAILURE. I WAS IN A COMA FOR NEARLY 2 WEEKS. I AM VERY, VERY LUCKY TO BE ALIVE. READ THE NEW WARNINGS FOR THIS DRUG, REQUIRED BY THE FDA AFTER DEATHS CAUSED BY MUTIPLE ORGAN FAILURE SUCH AS WHAT I EXPERIENCED. IT ALL STARTS WITH LOW BLOOD PRESSURE. IF YOU TAKE PROVIGIL AND START FEELING DIZZY WHEN YOU GET UP OR WALK AROUND, YOU ARE IN SEVERE DANGER. CONTACT ME AT BRUCEALAN@GMAIL.COM IF YOU EXPEREINCE THESE SYMPTOMS. THIS DRUG MUST BE TAKEN OFF THE MARKET.		M	54	3 months		4/20/2008 Email
5	MS related fatigue	Strong smelling first morning urine, racing thoughts, sometimes socially inappropriate comments	I take 200mg twice a day. My life would be a mess (spent dragging around or sleeping) without this drug. I can have a day that is productive; my mind focuses better, and my speech is not choppy. I am just more "me".	F	53	5 years		6/9/2008
5	SLEEPINESS, LETHARGY,FATIGUE	OCCASSIONAL NERVOUSNESS; OCCASSIONAL NAUSEA IF I DON'T REMEMBER TO EAT(SIDE BENEFIT-WEIGHT LOSS); OCCASSIONAL PALPITATIONS; & OCCASSIONAL DYSPEPSIA(CONTROLLED WITH PREVACID 15mg/DAY).IT MAY BE COINCIDENTAL, BUT I HAD CATARACT SURGERY APPROX. ONE YEAR AGO, AND RECENTLY WAS DIAGNOSED WITH ANTERIOR VITREOUS DETACHMENT IN MY RIGHT EYE. I KNOW THE CATARACTS WERE THERE PRIOR TO MY TAKING PROVIGIL, AND I AM NOT A MEDICAL PROFESSIONAL, BUT I WONDER IF PROVIGIL CAN CONTRIBUTE TO THE ACCELERATION OF AGE-RELATED MALADIES, SUCH AS MY AVD?	I AGREE-THIS MED MAKES ME FEEL MORE NORMAL. IT HELPS INCREASE MY SENSE OF WELL-BEING, AND I CAN "STAND" BEING AROUND PEOPLE, WHEREAS BEFORE I WOULD ISOLATE MYSELF BECAUSE I COULDN'T "STAND" TO BE OUT AMONG OTHERS. I HAVE EVEN BEEN ACCUSED OF BEING "CHATTY", FOR ME. ALL-IN-ALL, I AM VERY SATISFIED WITH PROVIGIL. I DO WONDER HOW LONG I WILL BE ABLE TO STAY ON IT W/O LONG-TERM, SERIOUS SIDE EFFECTS. ALSO, I FOUND THAT VARYING MY DOSE BETWEEN 200 & 400 mg/DAY WORKS BEST FOR ME(I AM A LARGE INDIVIDUAL), WITH ONE DAY OFF/WEEK(I DO THIS WITH ALL MY NON-CRITICAL MEDS TO GIVE MY BODY A "REST"). I HOPE THIS HELPS OTHERS.	M	53	6 months		10/28/2007
5	Alleviate sleepiness from Remeron	I am taking 100 mg - 50mg in morning and 50 mg in afternoon. I had headaches the first few days and they went away when I took aspirin.	I was proscribed Provigil to counteract Remeron, an antidepressant I am taking for anxiety. The Provigil not only made me less sleepy but also seemed to reduce my anxiety and depression. I have no side effects except very mild headache. I think this drug is great - expensive though, I hope it comes in generic soon.	F	53	2 months		9/2/2008
5	Fatigue from rhuematoid arthritis	None	Keeps me going great with no hyped-up side effects but so expensive and my insurance company won't cover for it unless a person has narcalipse	F	53	2 years		1/2/2004
5	Hypoxia due to brain injury	side effects are strong urine odor and loss of appetite. i rarely feel hungry and have lost 35 lbs since I started taking it, insomnia	Wonder drug gave me life back after hospital error which resulted in my getting 10x too much intrathecal med. developed hypoxia. i can finally drive and sit through church. no more embarassing moments of nodding of in inappropriate places. thank you God,	F	53	2 years		12/22/2006 Email
5	hypoxia/dsypnea	weight loss; worked great at first at 200mg. but, now it seems not as effective. Have been on provigil 2 years now. Love it, but I can still fall directly to sleep turning on the TV		F	53	2 years		1/19/2007
5	Daytime somnolence due to PLMD	Initial jittery feeling that resolved within a month and diarrhea which resolved in 3 months	Provigil has been a lifesaver for me. I can actually drive and work without falling asleep repeatedly	F	53	4 months		8/3/2004
5	SLEEP APNEA	NONE	GREAT	F	53	2 months		11/14/2007
4	Narcolepsy	No known side effects.	My excess daytime sleepyness has ceased. I am very pleased with this medication.	M	53	4 years 100 mg 2X D		4/13/2010
4	Excesessive Daytime Sleepiness	Provigil doesn't seem to be effective consistantly	When I first started taking Prov. It was wonderful because it kept me alert and able to work, drive and be apart of my family. But now after years of taking it, I find that some days, it doesn't work at all. I take 300mg every morning. If I choose to change that I can (per my neurologist) take 200 in the am and the remaining 100mg at noon. It is 200.00 a pill and so I am asking to be put back on Cylert. The side effects of cylert are liver damage so my hope is switch back and forth.	F	53	7 years 100 3X D		3/4/2010 Email
4	apnea	nausea and stomach pains	The benefits have been tremendous! No more day sleeping, nodding off! I'm back into life again, EXCEPT...for the horrible stomach pains (like cutting class) and nausea-to the point I can't work- so I'm just as out of it with the side effects as I was with the sleepiness. Anyone else have this problem? Anything help? How long does it last?I'm a teacher so I have to be on my toes,and doubling over in pain, running to the Rest room, and burping and flatulence are not too cool.	F	53	4 days		12/4/2006 Email
4	Obst. Sleep Apnea	'Growling' GI tract	Taking 'Indian' Modalert for 3 months. Works exactly as advertised. 100mg most days is quite enough to stay alert during working hours, 200mg if less than 7 hr sleep the night before. Can remember things that used to escape my memory. Definitely makes me more alert and more confident in my memory. 200mg will stoke me (6'1,235#), more than that approaches drug abuse. Do yourself a favor; lay off it on weekends, monitor your heart regularly, and don't exercise within 6 hr of taking a dose. It works for me!	M	53	120 days		10/5/2009
4	Depression	I'm prescribed 200mg/day, sometimes take 100. Started w/ 50. Difficult getting to sleep. Wake up too early. But not much negative effect from less sleep. Groggy upon waking. Jittery only when taken w/ caffeine. Slight blurred vision. Increased sex drive. Easily distracted. interrupted long-term memory (can't remember names of things like "Provigil") increased talking. Smelly urine, but who cares? A little more irritable.	This REALLY helped. I didn't realize how chronically depressed I was. 15 years ago I was involved in everything w/ lots of hobbies and active tasks. Always upbeat, never bored, positive outlook. Until I started taking this, I had lost interest in most things, not wanting to do much (age and marriage may have some effect here). Some euphoria early on, but that has mostly abated, some declining effect over time.. When I drop back to 100mg, it sort of "resets" the effectiveness. Increased sex drive may be from not being depressed. I am concerned of brain altering drugs and about potential of dementia and parkinson's because of dopamine altering.	M	53	1.5 years		3/28/2008
4	for SSRI apathy	Provigil does raise your body temperature a little bit so I felt hot sometimes. It also has a tolerance build up that is perceptible. So when you take it at first it is stronger and more effective than if used every day.	I think this works but works better if you take a weekend or a few days off here and there.	M	53	2 years		3/21/2009
4	daytime sleepiness	I have experienced some of the side effects listed in the other postings, but to a slight and transient degree. Some of these side effects may be due to several other meds I am on, or due to a combination of them, even though interactions are not indicated in the literature. Everyone's physiology and tolerance is different, I guess. The latest side effect, and most irritating to me so far, is tingling/numbness in my feet.	I have been on Provigil about 2 years, with doses from 200mg to 400mg per day. Lately, I have been taking 300mg/day in one morning dose. Also, I am told I am a low level diabetic with fasting blood sugar usually around 105. My doc has me on 100mg/day Januvia. When the tingling/numbness began suddenly in my feet, I became worried that the diabetes was progressing, rather suddenly. I am not very regimented in my diet, but I do exercise vigorously(walking hills and lifting weights) at least 4x/week. Anyways, I stopped the Provigil(300mg, 1xday) for 3 days, and the tingling/numbness in my feet stopped. However, my daytime sleepiness, and my irritability and anti-social demeanor(present prior to Provigil) returned very quickly. I took 100mg Provigil this a.m., and my feet are tingling. I am fairly sure I have developed a new(to me) side effect of the Provigil. I am going to call my doc Monday, and ask him if there is an alternative to the Provigil I can try. My family, my friends, and I, li	M	53	2 years		11/8/2008
4	energy and depression	When I started Provigil I immediately felt such an increased level of happiness, excitement, and energy. I am a flight attendant and I used it when I had to get up extremely early for flights. For awhile it seemed to be the best thing since sliced bread but then I noticed that it was making me more agitated as the day went on as well. I would get irritated at things that normally I would have been cool and collected about. But the main problem I found was that it increased my depression tremendously when I would stop taking it for a few days. I take paxil as well. I did enjoy the feeling it gave me for several hours after I took it.	really decreases your appetite.	M	53	3 months		1/25/2009
3	OSA treated with CPAP but still EDS	itchiness after taking 50 mg of Provigil... I split a capsule in fourths. I usually bounce out of bed today I did not.	Yesterday, My first day on Provigil I was not as sleepy. I was focused. But reading the side effects and experiencing the itchiness and not bouncing out of bed. I will discontinue and maybe give it another try in a few weeks. I think I would rather be sleepy....	F	53	1 days		4/23/2009 Email
3	fatigue	jittery,sleeplessness, elevated blood pressure,numbness and tingling		F	53	3 weeks		7/8/2002
2	bipolar meds sleepiness/apnea	lightheadedness, vertigo, euphoria after ingestion, crash in late afternoon, accelerated hypomania to mania	fighting side effects to see if time will alleviate	F	53	2 weeks		6/6/2007
2	excessive daytime sleepinness, apne	heachaches, nauseau	When I originally started taking it, I felt speedy. In last two days, the provigil seems to hjqave become ineffective. I can hardly stay awake behind the wheen of the car--can fall asleep anywhere. I am strugging to stay awake. It would be nice to know if anyone else built up a tolerance to provigil where the provil became ineffective.	F	53	1 days		5/25/2005
2	Adult ADD	mild headache; tearful; irritable - everything seemed to either make me cry or really annoy me.	Nice to not fall asleep at 7pm. Only took it for a few days before the crying and short temper seemed like they outweighed any advantages.	F	53	3 days		3/3/2006
1	sleep apnea/borderline narcolepsy	I had severe headache with full dose, but none when I split dose in half. Built up tolerance & used full dose during last yr on drug. Became super talkative had difficult controlling what I said during first few hours of taking dose & I am a very shy person. Drug did keep me alert during the day, but I did not realize until off the drug what price I paid for that alertness.	This drug is addicting! I feel like a different person. Clear of this drug for about 3 weeks now. I suffered extreme withdrawal (flu like symptoms) when I was unable to take the drug. After the withdrawal, depression I did not know I had lifted, my thinking process became clear and short term memory loss improved. I thought I had ADD and sought psyc help a yr ago. I almost lost my job and missed out on two separate promotions I did not feel qualified for at the time, all because of this drug. I was not consistently using my CPAP machine at night, but now I do and I have not felt the initial tiredness that I felt when I first started this drug.	F	53	6 years 200 mg 1X D		2/28/2010 Email
1	excessive daytime sleepiness, apnea	I have been taking this medication for about a year. When it works, it works. However, there comes a point when if I do not stop taking it for a few days, it has the opposite effect and I have sleep attacks. I have been having incidents of insomnia for 6 months that may be caused by provigil. Also, my migraines increased from on every one or two weeks to one a day. I also am experiencing muscle pain that may be caused by provigil.	The drug seemed too good to be true, and I think it is. I think there are long-term side effects like amnesia, sleep attacks, severe headaches, and possible muscle damage.	F	53	1 years		6/14/2005
5	I was tired all day long	This medication works. I took it in rehab and did not notice anything. I tried it six months later while sober and it worked great.I feel awake and I have a much more positive outlook. This medication has had a profoundly positive affect on me.		M	52	4 days		1/14/2007 Email
5	hypersomnolence	strong smelling urine, clenching	This drug has made a significant improvement in my quality of life. I was diagnosed with mixed (central and obstructive) sleep apnea, and faithfully wore my CPAP device to the prescribed levels with little improvement in my symptoms. I was diagnosed with borderline narcolepsy after a 24 hour stay at a sleep lab, and was put on provigil. Prior to provigil, I would regularly fall asleep at work or in meetings. I was afraid to drive alone for more than an hour for fear that I would fall asleep driving. (I had many close calls!). I have never felt any euphoria as described by others. The greatest drawback is the expense, but I compare it to the fact that I can keep my job and haven't wrecked any cars.	M	52	3 years 200mg 1X D		2/26/2010
5	Severe fatigue	Headaches, and brusing easily. I truly could not have a normal life without this drug. Started with 100mg, after two years went to 200mg. I just increased to 300mg, this is after 9 years.		F	52	9 years		6/14/2009
5	idiopathic hypersomnia	None	100 mg dosage, only during the work week. Very beneficial in helping to ameliorate afternoon drowsiness. Not a cure-all, but beneficial used as described.	M	52	7 years		12/2/2009

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Average rating for drug: 3.6. This page is printer-friendly; use landscape print with background color turned on.

Key to ratings: 5-Very Satisfied: this medicine cured me or helped me a great deal. 4-Satisfied: this medicine helped. 3-Somewhat Satisfied: this medicine helped somewhat. 2-Not Satisfied: this medicine did not work to my satisfaction. 1-Dissatisfied: I would not recommend taking this medicine.

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