PROVIGIL Reviews (MODAFINIL)

Average Rating: 3.6 (619 Ratings)

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 CNS, MISCELLANEOUS    DEA Schedule IV   

 Type: Rx Drug

  

PROVIGIL  (MODAFINIL):  Modafinil reduces extreme sleepiness due to narcolepsy and other sleep disorders, such as periods of stopped breathing during sleep (obstructive sleep apnea). It is also used to help you stay awake during work hours if you have a work schedule that keeps you from having a normal sleep routine (shift work sleep disorder). This medication does not cure these sleep disorders and may not get rid of all your sleepiness. Modafinil does not take the place of getting enough sleep. It should not be used to treat tiredness or hold off sleep in people who do not have a sleep disorder. It is not known how modafinil works to keep you awake. It is thought to work by affecting certain substances in the brain that control the sleep/wake cycle.   FDA Approval Date: 1998-12-24 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PROVIGIL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PROVIGILCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  Brain cancer and fatigue It started off keeping me awake and was great upon first use, I could talk more and I seemed happier. As I recovered from the illness it started causing severe euphoria insomia and racing thoughts, oh and my pee smelled funny. M 17 5 months
1/7/2010
 1  narcolepsy change in personality, mood swings, doing things out of character and lying about it This drug nearly ruined my life! I had and huge change in personality, I would have mood swings. I did things that were out of character for me and then I would lie about it. I was working two jobs and was constantly tired and was diagnosed with narcolepsy because I could not stay awake - well duh! I now take a nap in the afternoon and try to get more sleep at night - I am now off this awful stuff and living a very happy and content life! DON'T GET ON THIS STUFF IT WILL RUIN YOUR LIFE!!! M 26 16 months
1/7/2010
 4  Chronic Fatigue in Early Afternoon None. The drug works wonderfully. A benefit is weight loss. I think because I am moving more, I am burning calories and not able to focus on food. I have to admit that there are times when I want to sleep and sometimes I purposely don't take the drug. I really look for this medication to be prescribed more for depression and fatigue. Different drugs work differently for different people. I highly recommend this drug. I only need 1/2 tab taken about 9 am to get me through the day and avoid the early afternoon fatigue I get. I don't want the drug to interfere with my sleep, so I don't take it BID as was prescribed for me. I take this med very irregularly. F 52 6 years
1/1/2010
 3  extreme daytime sleepiness Fatigue, moodiness, muscle pain. Agitation at times. Possibly some paranoia or suspicion. If you are lactose intolerant, be sure to take Lactaid tabs with Provigil. The formula contains lactose. The jury is still out on Provigil for me: I don't like the psych side effects. It does lift depression but the minute I miss a dose, i feel despondent. I also feel my judgment and caution are off kilter when I take Provigil. As if I am overly-enthusiastic about things. Less prespective than I would normally have. F 55 30 days
12/17/2009
 1  chronic fatigue felt wired and energetic. later fatigued and passed out, hard time breathing. Stopped taking after saw small rash after 3 days. itchy skin, body pains, sore eyes, warm sensations in body, flu-like symptoms, fever, chills Took 25mg of provigil for 3 days. worked great the first day. 2nd and 3rd day I felt more fatigued and passed out. 3rd day I noticed a tiny harmless rash on my leg. Stopped because I've heard of Steven Johnson syndrome. Then experienced flu like symptoms, fatigue, malaise, itching, dry and sore eyes, body aches, warm sensations in skin, fever and chills. This is still ongoing, though it seems to be improving 8 days after discontinuing the drug. I'm very concerned. I'm not out of the water yet. This could develop into SJS M 23 3 days
12/17/2009
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 2  chronic fatigue started out great, within a few weeks started feeling very depressed. Starting having obsessive compulsive feelings. F 20 30 days
12/14/2009
 4  extreme daytime sleepiness possible hairloss, trouble staying asleep at night, paranoia at night, hot hands (i think it raised my temperature and my hands are usually cold), crash after 5-6 hours it works pretty well for me. i take 50 mg in the morning and then again at 1pm if needed. i am more alert, which i guess is what we're going for. F 24 2 months
12/3/2009
 5  idiopathic hypersomnia None 100 mg dosage, only during the work week. Very beneficial in helping to ameliorate afternoon drowsiness. Not a cure-all, but beneficial used as described. M 52 7 years
12/2/2009
 5  Depression, memory prob, fatigue The first day I felt "high" and disconnected. Since then,some dizziness on and off. OMG! I can function again. I am alert, have desire to do things, things aren't such a struggle because of fatigue and brain fog. I do notice when it starts to wear off. It has a "peak" time and then I go downhill. So I can't take it too early in the day. F 41 1 weeks
12/1/2009
 5  chronic fatigue syndrome It sometimes keeps me awake longer but not always. I have been taking provigil for about 5 years...it gave me a life! Unfortunately it hasn't made me want to stop eating but I can plan to do something and actually do it. I'm taking 150 mg tab in am.or 1/2 am and 1/2 around 1 pm it doesn't last all day. Around 2 or 3 in afternoon, I'm done. F 65 5 years
11/28/2009
 4  Sleep disorder NOS/CFS Headache, increase in allergies, little bit of jitteryness, maybe hair loss? (I have marked hair loss and thinning, but am not sure if it's a side effect of Provigil or one of the other meds I'm on.) This drug has been phenomenally helpful to me! I have a "sleep disorder not otherwise specified" (my sleep cycles are really messed up, so that sleep never feeling restorative or "good"), as well as CFS and related autoimmune disorders, and the end result is that without Provigil, I am a groggy, foggy, unmotivated MESS 24/7. It is so hard to get out of bed, to sustain my energy throughout the day, or to feel alert and present. I was very reluctant to start a medication that I could possibly become dependent on, but Provigil has been fantastic, and has, as so many people have said, given me my life back. The problems are: 1) I do still get tired around 3-5 pm, and if I want sustained wakefulness, I have to take a second dose; 2) when I try to stop taking Provigil -- which I have (see #3) -- I return to my groggy-mess state and am utterly miserable, and 3) I am uninsured, and paying for this drug out of pocket is HORRIBLE. I can't afford it anymore -- hell, I couldn't afford it 4 years ago! -- and I'm now in that wretched place of trying to live without it, and finding I really cant' do so, and wondering what the hell is going to happen to me. Ack! F 39 5 years
11/22/2009
 5  severe hypersomnia and depression HAD VERY SCARY CHESTPAINS, BUT ONLY FOR TWO DAYS. bEEN TAKING NOW FOR THREE MONTHS, BUT HAVE HAD VERY BAD HYPERSALIVATION DEVELOP AND GETTING WORSE.ANYONE KNOW HOW TO DEAL WITH THIS SIDE EFFECT/ wOULD REALLY APPRECIATE IF ANYBODY KNOWS HAS HAD THIS AWFUL HYPERSALIVATION, AND FOUND A CURE FOR IT? (APART FROM STOPPING THE DRUG).it is so helpful in all other ways, and given me a chance to live a normal life again M 56 3 months
11/16/2009
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 2  sleep apnea with daytime fatigue I started at 200mg for 2 days then cut back to 50mg for 3 weeks. Now on 100mg at 6:30am. Pain and cramping in legs which is getting worse. Increased difficulty in falling asleep due to overall muscle pain. This has increased daytime fatigue, sore eyes and sleepiness. I am in a total brain fog. I would rate this at 1 but it may be the best drug for some people. That is not for me to decide. This expensive treatment has been a total failure. F 63 34 days
11/13/2009
 1  chronic fatigue and sleep disorders Extreme tachycardia (over 200 beats per minute, very high heart rate!), chest pain and pressure, jitters, and actually increased sleepiness. Horrible experience. It was a risk given that I already have mild tachycardia, but it threw my heart rate through the roof. It took a couple hours to get back to normal, but it was a disaster. Surprisingly it even made me feel more tired. F 24 1 times
10/12/2009
 1  sleep apnea mood swings, changed personality and way of thinking, made me act inappropriately, RUINED MY LIFE!! F 35 9 months
10/11/2009
 1  narcolepsy My thinking was all screwed up - had mood swings - couldn't focus on anything. One minute I would be fine the next I was argumentative. Little things that would have never bothered me before became major issues. It almost destroyed my marriage - I would act inappropriately and had horrible mood swings. My family could see what it was doing to me and got me off this horrilbe stuff. I would have to say they probably saved my life and my marriage. DO NOT TAKE THIS HORRIBLE STUFF!!! M 26 10 months
10/10/2009
 4  Obst. Sleep Apnea 'Growling' GI tract Taking 'Indian' Modalert for 3 months. Works exactly as advertised. 100mg most days is quite enough to stay alert during working hours, 200mg if less than 7 hr sleep the night before. Can remember things that used to escape my memory. Definitely makes me more alert and more confident in my memory. 200mg will stoke me (6'1,235#), more than that approaches drug abuse. Do yourself a favor; lay off it on weekends, monitor your heart regularly, and don't exercise within 6 hr of taking a dose. It works for me! M 53 120 days
10/5/2009
 3  ADD depression anxiety tightness in the skin, jittery, insomnia It depends on the type of Provigil you have. The real stuff, Provigil, works wonders--makes you alert and able to keep at a task--but for me it peters out after a week of taking 200mg daily. The other kinds of modafinil, Modapro and Modalert do little to alleviate depression symptoms. That is especially true of Modapro. M 44 1 years
9/18/2009
 5  To help stay alert None I work swing shift and was having trouble staying alert while driving home in the morning. I have had no trouble since I started taking Provigil. I only take it 7 times a month while on night runs. M 55 8 months
9/16/2009
 2  MS-related fatigue, cognitive diff. Disconnected feeling, anxiety, tight-chest, splitting headache, muscle and joint pain, flu-like symptoms, dizziness, loose stools, nausea, weird dreams, sore behind eyes, sore feeling all over body. This is my third day taking Provigil and the worst symptom-wise. Took 100 mg the first day. After an hour experienced strange, disconnected feeling ("tripping" feeling) that lasted for about an hour. Five hours later, finally felt nice surge of energy that lasted throughout the eve. Weird and unpleasant dreams that night. I skipped a day, then took another 100 mg dose 2nd morning. This time no disconnected feeling, no energy surge, just loose stools, mild nausea and muscle stiffness. By nighttime was sneezing with runny nose and congestion. I didn't connect any of this to the Provigil--assumed it didn't work and that it was time to up my dosage to the rec. 200 mg. So today, day 3, I took 200mg in the morn. w/ breakfast and coffee. Half hour later had same weird out of body feeling. Lasted about an hour; following that, a crushing sensation in my chest. I was panting, anxious, w/ nausea and loose stools. Later in day developed splitting headache, sore muscles, and dizziness on top of earlier symptoms. Maybe I'm coming down with something, but after reading some of these comments I'm thinking it's the Provigil. Also taking 4.5 mg LDN at night for MS, no other meds. Can't find info on poss. drug interactions w/ these. I've had MS for 13 years and my fatigue has become debilitating. Was hoping something would finally work. I'm so desperate for fatigue relief that I'm willing to keep trying, but not if I feel this bad all the time. Do these side effects go away? I feel l F 37 3 days
9/8/2009

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