ZYBAN Reviews (BUPROPION HYDROCHLORIDE)

Average Rating: 3.2 (580 Ratings)

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 ANTIDEPRESSANTS SMOKING CESSATION AIDS UNCLASSIFIED

 Type: Brand name discontinued; available as generic

  

ZYBAN  (BUPROPION HYDROCHLORIDE):  This medication is used in combination with a stop-smoking program (e.g., support group, counseling) to help you quit smoking. Bupropion can decrease your nicotine withdrawal symptoms (e.g., irritability, anxiety, restlessness) and your urge to smoke. Quitting smoking decreases your risk of heart and lung disease, as well as cancer. This medication belongs to a class of medications known as antidepressants. It is not known exactly how bupropion works to reduce smoking urges. It may work by restoring the balance of certain natural chemicals (neurotransmitters) in the brain. Discuss the risks and benefits of this medication, as well as other ways to quit smoking (such as nicotine replacement treatment), with your doctor.   FDA Approval Date: 1997-05-14 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by length of time drug was taken longest to shortest.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR ZYBANCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  smoking Moderate to severe GI Tract problems--GERD, constipation, Flatulence, cramps,the Trots, fluid retention, bloating, (Large water weight gain)etc Bad taste, dry mouth, ringing ears,Stimulant effects, Insomnia, Spacey. Dull headache. Dry eyes. It Worked--I quit. 5 smokes/day for 2 weeks ...and then zippo since!! Urge to smoke killed in less than 20 days (cig Flavor killed).(150 mgs-2 weeks--then 200 mgs --then 300 mgs --now down to 150 mgs every other day.) Smell improved. Taste improved. Breathing great-never cough anymore. 10 days of heavy dark "Lung-gunk"--very little since. Very productive Jan-Feb at work. Slept 3-4 hrs / nite. ( 5 -7 is normal) Work horse feeling- No Procrastination--except for GI issues and bathroom. Slowing down a bit here in March. reducing dose to every other day. Trying to hold on for 5 more days..and then titrate down to once every 3 days, then 4 days, then 1x/week...then Zippo by April 15th. I tried the other (Vanceril) but GI side effects were worse !! I lasted 3 weeks on it. Zyban is very similar--just not as intense. I wanted to blow someone's head off on the Vanceril. Guts/GERD really baaaad on that Drug. Less so on Zyban. Good luck all !! Nebraska M 51 70 days
3/11/2009
 5  stop smoking I have been a smoker for 40 years. Struggling to quit for 20 years. I took Zyban 6 years ago and after 3 days had lost interest in smoking. Never smoked since. Cannot remember side effects they cannot have been that serious HOWEVER, I had a serious episode on the last day of the treatment. I became enraged at a neighbour who had been giving me a hard time for 5 years and I went in his garden and destroyed it, like the Incredible Hulk. Next thing I know, I wake up in bed with total memory loss of the last 20 minutes. I have a question. SInce I quit smoking with Zyban, (6 years) I have been a different person. No enthusiasm for life , no interest in doing anything. I used to be very active, I now spend my time reading and playing with computer. Not depressed, just going through the motions, without any real motivation. Is it possible that ZYban has permanently affected my brain? affecting the reward centres ? Anyone with the same experience, months after quitting with Zyban ? ALso a message to all of you who feel depressed. I have stopped smoking many times, cold turkey or with patches and everytime I would feel very angry. Within days I would hate my life and everyone in it and feel suicidal. It is the nicotine withdrawal. No Zyban. Talk to your GP. Get antidepression pills. Nicotine addiction is very serious and there are a lot of withdrawal side effects -physical and emotional. You are not being a sissy by getting help. F 63 60 days
1X day
12/24/2011
Email
 4  Quit Smoking Possibly Hives.... Still trying to determine. It took the edge off. M 28 60 days
10/19/2004
 4  to stop smoking Hot flushes. Think there could be hair loss. Dry mouth. F 53 56 days
150mg 2X day
1/16/2011
 4  Quit smoking Sleeplessness first few weeks. Loss of sex drive, erectial dysfunction, anxiousness, dry mouth. It will decrease nicotine cravings, but you have to put up with a load of crap. Beats smoking however. I'm just glad I'm off the stuff now and my life is back to normal. M 46 55 days
5/18/2005
 4  Quit smoking It started of fine when I went to two tablets a day. I didn't want a smoke after 20 years. Just the craving a couple of times a day. Just pop into head and then gone straight away. Then the mood swings started! The irrational thoughts. The paranoia. The aggressive behaviour. I have 4 days to go and my husband is tring to hang in there. My 15yo daughter just stays out of my way as I seem to just come down on her hard about everything. For no rational reason that I can think of later when I go over what happened. But all the time this is happening the cravings are just about gone.Sometimes days apart. I had a drag of one about 8 days ago. Yuk. Didnt like the taste or what it felt like in my lungs. Not for me ever again. I just hope that after al of this that I will find out that is is the Zyban, just not me without smoking. Reccomend this to others to quit smoking. But under close watch from loved ones who can support you through this and remind you that what you are doing and feeling is for the best for not only yourself but yor family and friends around you aswell. F 35 54 days
3/4/2006
 4  Stop smoking Severe Anxiety and depression, crying fits, hard to sleep, decreased appetite, restlessness and pacing, lack of focus and motivation, suicidal thoughts. Felt like I was going insane. Scared myself enough to wean off and stop the pills. I wanted to quit smoking and I did. Easily, and I couldn't be happier. I was aware of the side effects going in and had support when I was experiencing my artificial reality. When it got more than I could handle I went back to 1 pill a day for a couple of days then I stopped. Feeling confident with not smoking because it felt easy and I also am not going thru the emotional roller coaster ever again. I would recommend for smoking only if you are fully aware of the side effects AND have a support system to talk you thru them, realizing you are experiencing an "artificial reality". F 50 54 days
150mg 2X day
8/17/2020
Email
 2  Smoking Cessation Dry mouth, forgetfulness, some shakiness in the first few days. Stopped smoking in the second week and did not have many cravings for tobacco at all. After I upped the dose to 2 pills started feeling really depressed, had days where I was crying uncontrollably, felt useless. Suicidal thoughts etc. Cried for days on end, which is something I never did before taking Zyban. My partner is taking it as well and she has some of the same symptoms, e.g. dry mouth, loss of sleep and appetite etc, but none of the physchological effects. I was about to make an appointment with my doctor regarding the depression when I found this site and realise now it is a common side effect. Have not smoked for 7 weeks so feel good about that, but this drug needs to be taken very seriously and I will be letting my doctor know the potential side effects. Have not felt this bad physchologically in my life. Would not recommend it to people unless they have tried everything else and they know the risks. Thought I was going mad. Hope to God this wears off quickly. F 47 46 days
1/27/2010
 5  Nicotine addiction This is really a follow up to my previous rating. See below - Same title!! Side effects have subsided to virtually nothing. Some irritability (Mind you, I always was a prick!! :-) and a little bit of tiredness but nothing worth mentioning. Well I had my last cigarette over a month ago and have managed to stay smoke free in all environments including clubs and bars which I thought would be impossible. Getting to th epoint where I can now no longer stand the smell of smoke. However, do still get the occassional craving. Will be dropping off medication from two a day to one a day for remainder of course sometime this week. All in all, I've survived and rarely think about smoking now. The medication has definetly done what it was supposed to, and I look forward to a much happier and healthier cigarette free life!! good luck to you all! M 33 45 days
7/17/2006
 5  Stop the Cig Habit At first, a little dry mouth but nothing I couldn't handle. No extreme side effects at all (lucky me). The only other issue I've experienced is a lack of coordination/concentration. This is not good for a drummer. There is NO WAY I could have stopped smoking without Zyban (at least a pack a day for 22 years). Really helps minimize the cravings and provides a "no big deal" attitude towards quitting. I am a little concerned about coming off the drug. Will cravings come back when I quit? Don't want to be dependent on any medication. Drinking intensifies the urge to smoke so I suggest avoiding excessive drinking. I haven't had a smoke in exactly 30 days (but who's counting). F 36 44 days
4/26/2006
 5  stop smoking The dizzyness IS starting to get a little worse,cant read for too long my consentration while driving is now effected.I dont feel 100%safe behind the wheel.Sleep is rubbish,been sleeping for 2 half hrs each night cant take sleeping tabs cos i have a 1yr old that still wakes up for milk.I'm now getting SO forgetfull it's doing my head in.Still bloody stressed with everyone and everything.Itching still has not died but i'm not breaking out in white lumps all over my face any more. I'm two down from this comment,just wanted to say i was on about day 25(ish),as in length of time taking zyban.It's printed as 5..my mistake!Now on week 6-day 42. F 27 42 days
2/27/2006
 5  stop smoking The dizzyness IS starting to get a little worse,cant read for too long my consentration while driving is now effected.I dont feel 100%safe behind the wheel.Sleep is rubbish,been sleeping for 2 half hrs each night cant take sleeping tabs cos i have a 1yr old that still wakes up for milk.I'm now getting SO forgetfull it's doing my head in.Still bloody stressed with everyone and everything.Itching still has not died but i'm not breaking out in white lumps all over my face any more.Cant swallow things like bread and chips,feel like i have a huge lump in my throat but it's not sore.Only got 2 weeks left on this drug and i'm worried to hell cos the nurse said she wont wean me off,she'll just stop...i'm going to go out of my head..it's bad enough now! I'm two down from this comment,just wanted to say i was on about day 25(ish),as in length of time taking zyban.It's printed as 5..my mistake!Now on week 6-day 42. F 27 42 days
2/27/2006
 5  to quit smoking as described by pharmacy-restless,some joint pain tightness in chest, some ringing in ears, some anxiety. Now how many of the symptoms are caused by nicotine withdrawal as well as the caffeine withdrawal(i also gave up the bean, don't go cold as i did wean yourself it'll be less painful). I've read the comments and side effects here and wonder how many were caused by misuse and improper dosage of the drug...ya gotta do what the dr. says, no alcohol, no double dosing, wait 8 hrs between doses, and pay attention to the side effects, not all drugs are for all people side effects can be deadly be aware and you'll love the effects. after several attempts in my life to quit smoking zyban has given me new hope that i can be nicotine free. I hate the fact that i haven't been able to quit without an aid but hey the ends justify the means . M 37 41 days
3/6/2006
Email
 5  stop smoking Stomach pain,weird dreams.jittery.dizziness Haven't had the urge to smoke.Using patches alsoI am experiencing a very tender stomach.I guess that's 1 of the side effects I hope it's nothing else M 56 40 days
12/27/2006
Email
 5  Stop Smoking Some insomnia, mild Dizzieness, some mild Bladder weakness in the 3-4 week, .........Dont know if this was a side affect or my body screaming for nicotine, but developed "irritable bowl syndrome" while quiting, and have had it ever since. Zyban is the greatest! Was a 30-35+ cigarette a day man! Had tried everything ,Patches, Nicorette even hypnosis ! Tried quitting on day 8 and only lasted 6 hours, so though hes another con, but kept taking the tablets and stopped again on day 14 and bugger me no withdrawal at all, just felt abit fuzzy like having a head cold for a couple weeks. Havent had a cigarette for almost 5 years now!!! Watched my Dad die of lung cancer at age 59, Docs said apart from his cancer, every other part of him was in great shape if he hadnt smoked he would still be round. Give it good nudge people!!! Rather suffer mild side affects and a windy guts, to kick those killer cigarettes for good. M 37 40 days
1/28/2007
Email
 3  To quit smoking In the beginning it made me UNBELIEVABLY aggressive, where I am usually a passive doormat. After that, nothing. No sleeplessness, nothing. I don't have any cravings for a cigarette, I have no desire, I am not stressed or irritable. Easiest thing I have ever done. I have regular spotting during cycles, and my skin broke out. F 32 40 days
3/9/2006
 4  Stop smoking Breathlessness, headaches, occasional migrane specially when sexually aroused to an extent that would rather not have sex! Slightly weird dreams.. sinus pressure (slight) occasionally feel a bit urgh... Have managed to not smoke now for over 4 weeks. Still have the occasional twang for a fag, but it soon goes. Find not smoking really boring, but hey, I'm feeling healthier by the day and I don't want to die from Cancer like my brother did. It's stopping me smoking, so as long as the side effects dont kill me..... I'd recommend it still... M 45 37 days
150mg 2X day
12/20/2011
 5  smoking chronic insomnia, increased appetite, vivid dreams. After smoking for 44 years, Zyban allowed me to give up smoking with no cravings at all.On day 36 and 10 days to go.Good thing I'm retired as I'm tired all the time- but it's well worth it! M 62 36 days
2/27/2007
 5  Stop Smoking This is the 3rd time I've taken Zyban. For reasons that are beyond me I stopped smoking for 3 months and started again. This time there won't be a thing on this earth that will make me start smoking again...as I can't take Zyban any more. The foul breath, bad taste in my mouth, massive mood swings and during this last prescription such massive depression that I've had suicidal thoughts. This is not me at all. I've stopped taking Zyban. Luckily I've also stopped smoking. This drug is not for everyone...but it was the ONLY way I've managed to stop smoking. M 48 35 days
12/17/2007
 4  to quit smoking shakiness - constant buzzing in my head - quit taking it after 5 weeks and still have the buzzing 8 months later F 64 35 days
6/10/2004

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