ZYBAN Reviews (BUPROPION HYDROCHLORIDE)

Average Rating: 3.2 (580 Ratings)

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 ANTIDEPRESSANTS SMOKING CESSATION AIDS UNCLASSIFIED

 Type: Brand name discontinued; available as generic

  

ZYBAN  (BUPROPION HYDROCHLORIDE):  This medication is used in combination with a stop-smoking program (e.g., support group, counseling) to help you quit smoking. Bupropion can decrease your nicotine withdrawal symptoms (e.g., irritability, anxiety, restlessness) and your urge to smoke. Quitting smoking decreases your risk of heart and lung disease, as well as cancer. This medication belongs to a class of medications known as antidepressants. It is not known exactly how bupropion works to reduce smoking urges. It may work by restoring the balance of certain natural chemicals (neurotransmitters) in the brain. Discuss the risks and benefits of this medication, as well as other ways to quit smoking (such as nicotine replacement treatment), with your doctor.   FDA Approval Date: 1997-05-14 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Age oldest to youngest.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

Page: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29


RATING  REASONSIDE EFFECTS FOR ZYBANCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  smoking cessation Do NOT drink alcohol when on Zyban! Unfortunately, I forgot and drank a double whisky. I spent a night in the ER, following the most unpleasant experience I've ever had. Extreme drunkenness, difficulty breathing, nausea etc. No other additional side effects noticed. Will continue with the course. M 44 6 days
150mg 1X day
5/29/2010
 3  Smoking cessation Dry mouth, constipation alternating with diarrhea, mood swings, crying, ieritability, insomnia post nasal drop Had already quit for at least a month but started zyban to help with weight ( not what I told the doctor tho). gain. Had these side effects and stopped for a bit started back again couple of times. Every time I stopped I would have food cravings again and gained 3 pounds inn a day or so. not sure how. So it does work to get rid of food. Craving s, no longer had much craving for cigarettes when I started on zyban so can't comment on that. I quit with the e_cig F 44 3 weeks
150 2X day
10/13/2010
Email
 2  Depression Initially I felt an increase in energy and some insomnia, though I felt like springing out of bed on only a small amount of sleep/broken sleep. My libido went from nothing to closer to the days of when I was a randy 20 year old! Constipation set in quickly but I put up with it because my mood actually felt better than on the ssri's (my last one I'd been on before zyban was cipramil/celexa.) However I noticed a terrible rage creeping up on me after about the first week, then feelings of depression and the 'logicality' of taking my own life. To me, not worth it and I have felt better since stopping. By the way, my appetite increased and I couldn't stop eating contrary to other peoples experiences. Resulting weight gain! As one of the few Aussies who has attempted this for depression (in America it is called Wellbutrin and is marketed for depression and mostly taken for this) I can say that despite initially feeling a bit better (first few days) this was for me a very dangerous and insidious drug. My libido shot up so much I spent an interstate holiday looking for sex shops so I could buy a toy rather than sightseeing (I kid you not!) I enjoyed this side effect after years of lack of interest. Within a few days of stopping its still through the roof! But the downside was an out of control rage and genuine feelings of worsened depression to the point I calmly began to plan my demise. I have felt heaps better since the three days ago when I stopped cold turkey. Check out the 'Wellbutrin' reviews on this site. Who knows it could be your wonder drug for depression/smoking cessation but please take care if you have pre-existing depression. Get family to moniter you and present at Casualty if you are planning suicide. Your family and friends will be devastated if this drug takes you from them!! My recommendation though, avoid! F 44 18 days
150mg 1X day
2/12/2012
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 2  Cessation of Smoking I have never suffered with an allergic reaction to anything. However Zyban managed to produce the most massive amount of hives from head to toe in under 12 hours. Actually did stop smoking around day 8 with just a couple of puffs till day 10, on day 18 about an hour after my 2nd tab I noticed a slight rash and thought i may have been bitten by something. By the next morning I was covered with Hives, I didn't risk taking another and Dr confirmed I should NOT... F 44 18 days
3/24/2007
Email
 1  to give up smoking my brother took Zyban for 2 weeks prior to commiting suicide,I seriously suggest you do not take this,especially if you`re not feeling "stable" beforehand the doctor put him on Zyban even though she knew he was depressed....we had no idea he felt soo low as to do what he did,having taken it myself in the past,I was worried for him as I had feelings of self harming or harming others,I was psychotic pretty much..we`ll never know...would he still be here now if he hadn`t taken this potentially evil pill M 44 16 days
5/23/2008
 1  Quit smoking Once I hit two tabs a day: shakiness, nervousness, anger, irrationality, depression. Very mood-altering and not for the good. Side-effects were completely beyond my ability to handle. Couldn't last more than a week on this due to aweful side-effects and it never seemed to have an effect on my urge to smoke. M 44 7 days
4/5/2005
 1  Quit smoking Depression, irrational, violent. 2 years later trying to pick up the pieces of what is left of my life. Now classed by some ex friends as BPD. Took the stuff for 5 weeks. Never again. M 44 6 weeks
10/4/2004
 1  Stop smoking Anger, depression, anxiety, sleeplessness, restless Don't put yourself through it, it's not worth your mental health! Dr assured me I'd be fine, I am NOT fine, serious outbursts of severe anger, mental breakdown at day 12, stopped the tablets immediately. F 44 12 days
2X day
6/10/2022
Email
 5  stop smoking only side effect was very itchy hives that i still cant get rid of had smoked 40 cigs a day for almost 30 years.I had tried many times to give up using patches gum etc and at last something worked.Even my Doctor was suprised.I think there comes a time when you really want to stop and my time had arrived. F 43 9 weeks
4/16/2007
 5  stop smoking Phew...angry, pissed off, paronoid. Frustrated, argumentive, depressed, anxiety, yet better than last time I went on them in 2001, I got hives only about 5 hrs sleep a night, extreme aggitation..I have stop smoking yet alcohol is still a trigger.… F 43 7 weeks
11/28/2011
 5  Quit smoking N/A M 43 1 weeks
30mg
10/8/2013
 5  To Assist with Nicotine Addiction Vivid dreams, dry mouth, insomnia, loss of appetite I had a smoking quit date of 3 weeks after starting meds, but quit after a week and have not had any cravings for nicotine. Reading everyone's comments, this medication is obviously not for everyone. I would suggest that if you are trying to quit nicotine, try Zyban for a day or two. If you are getting side effects that are unbearable to you, then stop taking it. For me, I can handle the side effects. It is worth having the side effects than to go back to smoking. F 43 20 days
150 MG 2X day
4/30/2013
Email
 4  stop smoking since taking zyban, i have been spaced out, wondering if there is something wrong with my memory, it's gone really bad, have to think really hard to remember something simple. for the first couple of weeks i couldn't sleep, took me 2 hours to fall asleep. a bit of shaking, faster heartbeat, more emotional, lack of appitite. i am also suffering from blurred vision which is very annoying. seem to be calmer but at other times would take things to the extreme. more sensitive, i would take offence at the slightest thing. also suffering from lightheadedness. at times i also noticed that i have to read something a couple of times to get it in my head. it's been over 2 weeks without a cigarette. it was time to give up and after trying many times to quit, with patches, i decided to go on zyban. it is working wonderfully on the quit smoking side of things. i know now that i actually quit since i wouldn't think of smoking again, and even when i get the urge, it goes away rather quick. highly recommend it for quitting smoking if you can tolerate the side affects. F 43 20 days
11/7/2005
 4  To quit smoking tiredness and the craving to actually smoke more I am on Zyban and took one pill for 7 days and am now on 2 pills so far for 4 days. I am very tired could snooze alot, but other than that I find I have a stronger craving to smoke. My quit date is in three days hope this works, have smoked for 30 years a pack a day F 43 11 days
10/20/2005
 4  to quit smoking tiredness, craving to smoke more, posted earlier as a # 4 rating, still have side effects, tiredness and hard time getting in a deep breath but not trouble actually breathing I haven't smoked for 4 days, it really does take the edge off. I have a feeling that some of my side effects are withdrawal symptoms. Zyban is a brain drug and I think everyone has to keep that in mind when taking it. Have read that some drink while taking Zyban, that is just stupid. Use common sense. F 43 18 days
10/27/2005
 4  Stop smoking Initially anxiety and slowed down my analytical thinking. Thereafter pretty much ok, some feeling of detachment and warped sense of time. Initially used for 5 days. Experienced side effects after ramping up to 300 mg. Stopped for 5 days and started thereafter again. That time no probs. and a much easier time. Works great! M 43 11 days
4/25/2007
 3  to quit smoking I’ve been on zyban for 9days (17 150mg doses). Strange things started to happen by the fourth day that got progressively worse and more intense by the 9th day. 1. I can’t sleep, I wake up 3 to 4 times a night 2. I have no appetite what so ever, I have to force myself to eat. Lost about 5-10 pounds. 3. The depression is getting severe; I can’t focus on one happy thought. Everything is doom and gloom. 4. I cry for no reason. 5. I’m starting to get severs panic attacks, It feels like I can’t breath and I just want to jump out of my body. Intense shortness of breath. Severe anxiety like I’m having a heart attack. 6. Constantly pacing back and forth to help alleviate the anxiety. If I keep moving it helps. 7. Constantly thinking about death. How am I goings to die when am I going to die, just crazy stuff. 8. Occasional thoughts of suicide. not so much in that I want to kill myself just a morbid interest on the subject with occasional flashe It did what it was suppose to do help me stop smoking, Even though it's been only 9 days, I haven't had a desire to have a smoke at all. But the side effects were not for me. I saw my life flash before my eyes... I finally realize health is everything in life ..health is life...good luck to all .. I hope you don't go through what I went through M 43 9 days
4/17/2006
Email
 1  to stop smoking paranoid aggressive anxious lack of sleep weird thoughts of harming others This drug nearly cost me my relationship, its totally not safe, the side effect i feel if I have continued would have proberbly ended up with myself being locked up for hurting someone, seriously not good, I have never been an aggressive person and normally see the best in people, but this drug is terrible, M 43 3 weeks
150 mg 2X day
1/5/2012
 1  Anti smoking DO NOT BELIEVE ANY REPORTS THAT ENCOURAGE YOU TO TAKE ANTI-SMOKING DRUGS. THEY ARE EXTREMELY DANGEROUS AND HAVE A HISTORY AS BEING MARKETED AS ANTI-DEPRESSANTS, WEIGHT LOSS DRUGS AND NOW ANTI-SMOKING DRUGS. THEY CAUSE SEVERE ANXIETY, DEPRESSION AND PSYCHOSIS WITH LIFE LONG ILLNESS AND THERE HAVE BEEN MANY DEATHS FROM THESE DRUGS. RESEARCH RESEARCH RESEARCH AND DON'T, UNDER ANY CIRCUMSTANCES, TAKE THESE DRUGS. M 43 5 days
30mg 1X day
6/29/2010
 1  quit smoking anxiety,slurry speech, palpitations, very bad mood, agresive, etc. etc., etc. I took this pill before to quit smoking and I stayed away rom cigarrettes for 4 months. My husband also quit with Zyaban. I decided to go back to it because I really feel ready this time. After 5 days I have had to stop. The side effects are too much for me. I'm the kind of person that hates taking any king od medication. I don't evn take pain killers after surgeries. This time I was very god taking the meds twice a day. What a mistake. Now I want to know if I can take xanax to calm me down. I need to take something to stop the palpitations. I guess this med works for some people but If I had known before of the side effects, I would have never taken it. I can't believe it is still in the market. Too many people get sick because of it. F 43
9/29/2007

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