ZYBAN Reviews (BUPROPION HYDROCHLORIDE)

Average Rating: 3.2 (580 Ratings)

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 ANTIDEPRESSANTS SMOKING CESSATION AIDS UNCLASSIFIED

 Type: Brand name discontinued; available as generic

  

ZYBAN  (BUPROPION HYDROCHLORIDE):  This medication is used in combination with a stop-smoking program (e.g., support group, counseling) to help you quit smoking. Bupropion can decrease your nicotine withdrawal symptoms (e.g., irritability, anxiety, restlessness) and your urge to smoke. Quitting smoking decreases your risk of heart and lung disease, as well as cancer. This medication belongs to a class of medications known as antidepressants. It is not known exactly how bupropion works to reduce smoking urges. It may work by restoring the balance of certain natural chemicals (neurotransmitters) in the brain. Discuss the risks and benefits of this medication, as well as other ways to quit smoking (such as nicotine replacement treatment), with your doctor.   FDA Approval Date: 1997-05-14 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Satisfaction lowest to highest.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

Page: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29


RATING  REASONSIDE EFFECTS FOR ZYBANCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1   Horrible. Terrifying in fact. Left me with hectically worse depression, anger, depersonalisation. Be careful with this medication. If you can fight without it, a better option. Worsened my depression and anxiety tenfold still suffering 2 months off. M 53 2 months
1X day
5/24/2023
 1  My husband took to stop smoking Zyban send my husband into psychosis. In and out for a week then he finally snapped . He stabbed me multiple times in a psychotic rage . Three months later he committed suicide. So please don't put your family through the hell that I went through. M 43 5 months
1X day
2/20/2023
 1  Stop smoking Anger, depression, anxiety, sleeplessness, restless Don't put yourself through it, it's not worth your mental health! Dr assured me I'd be fine, I am NOT fine, serious outbursts of severe anger, mental breakdown at day 12, stopped the tablets immediately. F 44 12 days
2X day
6/10/2022
Email
 1  Anxiety My doctor put me onto Zyban as the escitalopram that I had been of for 6 years seemed to be not working. I was gaining weight and struggling to lose it. I started zyban 3 weeks ago. I stopped my escitalopram tapering it off in 4 days and adding zyban in once a day at first then two a day. The first week I noticed I wasn't as hungry and had Wicked dry mouth..so i was drinking lots of water..doesnt sound so bad does it. By the second week..i started having panic attacks..started to lose my personality..and became depressed. I lost 7 kgs in 3 weeks The third week..this past week...has quite literally been a nightmare. I had derealisation..feeling like you are in a world that isn't real...and it was scary. I couldn't sleep..when I did I had vivid dreams. I went to my dr 5 times in the 3 weeks and she was adamant this drug was the right one for me..i just had to ride the side effects out. The day after a drs visit I called the ambulance. I felt like i was going to pass out..probably from lack of food.. or pure fear. I went to the dr again the next day (yep should probably have a mug with my name on it by now) and she said to keep taking lorazepam to squash the side effects and assured me again..this too shall pass. That night ( last night) I hit rock bottom. I felt like i was a burden to my family. I would never hurt myself im too scared of dying..but i just felt like a massive burden and a complete mess. I emailed the drs and told them to ring me immediately in the morning. F 29 3 weeks
300mg 2X day
8/5/2020
Email
 1  To stop smoking Extreme debilitating panic attacks I am sure this drug is good for some people but it ruined my life for 3 years or so, from a position of having no mental health issues at all. Looking back I think I was experiencing work anxiety and occasional panic attacks - as such, I should never had really started taking them but I thought it was super important to stop smoking. Upon taking my tablet on day 6 I felt extremely ill and thought I was going to have a heart attack. It turned out to be a panic attack and these continued for 3 years, sometimes up to 30 or so times a day. Very slowly due to counselling and a short period of medication my panics grew less and less. I do not think Zyban was in itself the cause of my panic attacks but I believe it triggered them. I have never smoked since but it was a heavy price to pay - I simply can't recommend it for anyone as it truly ruined my life for 3 years. I was about 32 at time of treatment. M 50 7 days
1X day
5/20/2020
Email
 1  smoking cessation 1 days
8/3/2015
 1  to stop smoking started out taking 1 pill (150mg) a day, no problem , day 2 noticed sleep disturbance day 3 3 hours of sleep day 4 increased to twice a day uncontrollable crying even woke up crying day 5 still crying....stopped taking Zyban would never take this drug again, hated the side effects F 55 5 days
150 1X day
6/23/2014
 1  Stop smoking Painful shingles (rash). Lack of concentration. Still smoking. M 40 6 weeks
30 mg
10/12/2013
Email
 1  Quit smoking I had appearing a rash on my penis. It was literally raw. I went to my doctor and was treating me for some kind of burn . I figured out it was not external but internal. Once I stopped taking it, I began to heal. I even contacted the FDA to let then know of my adverse reaction to this drug. M 60 7 days
30mg
7/10/2013
 1  Quit Smoking Forgetfulness, absence of perception, jitter, spasm in the muscles, ache in the eyes, TINNITUS (RINGING OF EARS), NUISANCE and INTESTINAL DISORDER PLEASE READ THIS, I THOUGHT I WAS DYING!! I smoke one pack of cigs per day for 3 years. I have tried every single thing and finally I have learned Zyban, I have read some comments on the internet and bought it. During first 5 days on Zyban, I experienced forgetfulness and absence of perception. I have thought I can bear these symptoms . Then I started to be scared of almost everything, from crowded places, cars etc. Anyway, I didnt care about this. On day 13, when I was alone in my room to sleep at night, my two ears started to ring terribly. At first I didnt think this is the side effect of the drug. Then on day 14, at night, I experienced same things, this time I couldn’t sleep due to ringings in my ears. After I have slept, I woke up every one half hour or something like that. The following morning, on day 15, I thought this may be side effect of Zyban, I still took the drug. On that day, at night, I have looked up internet, and learned that tinnitus is a very serious symptom. I decided to give up the drug, and then again tried to sleep with the bells on my ear. At night, I felt jitters on my arms and legs and there was secretion in my ears.This morning, day 16, when I woke up my muscles on my legs and arms were stiff, there was an ache on my neck. Today I didnt take the drugs, about two hours ago I had a severe nuisance and intestinal disorder. My face went white and I was so scared that I thought I was dying. My abdomen was bloating, there was a slight ache on my stomach. After half an hour, I went to toilet I had constipation. Then again I went to toilet and this time I had diarrhea. I felt terrible but relieved as the ache and bloating on my abdomen was gone. I am still F 23 16 days
150 mg 2X day
9/10/2012
Email
 1  No Smoking DO NOT TAKE THIS DRUG!! SPACED OUT MOST OF THE TIME, RASH ONE WEEK LATER, TO SCARED TO TALK TO PEOPLE AND IM A SALESMAN (13 YEARS) SHAKES. DO NOT TAKE THIS DRUG! M 32 9 days
150mg 2X day
7/16/2012
Email
 1  I wasn't WARNING WARNING WARNING. ZYBAN IS ONE OF THE MOST DANGEROUS DRUGS ON THE MARKET. THE HISTORY IS THAT IT WAS MARKETED AS AN ANTI DEPRESSANT. IT KILLED MANY AND SENT OTHERS PSYCHOTIC. IT WAS TAKEN OFF THE MARKET AND REMARKETED AS A WEIGHT LOSS DRUG. IT KILLED MANY AND SENT OTHERS PSYCHOTIC. IT WAS TAKEN OFF THE MARKET AND REMARKETED AS AN ANTI SMOKING DRUG. IT HAS KILLED MANY AND SENT OTHERS PSYCHOTIC. THE DRUG AUTHORITIES IN ALL COUNTRIES ARE WELL AWARE OF THIS. SOME PEOPLE CAN TAKE IT BUT MANY HAVE HORRIFIC SIDE EFFECTS THAT CAN AFFECT THE REST OF THEIR LIVES. NEVER EVER EVER TAKE THIS DRUG. NEVER EVER EVER TAKE THIS DANGEROUS DRUG F 45
1X day
3/22/2012
 1  stop smokeing bad head akes bad nightmers constapation scin tight on face.bad taste in my mouth/sinus pain.musles hert.vouise tone changes.cold scin. wood not recomend these tablets. 4/2/2012. M 47 4 days
150mg 1X day
2/3/2012
Email
 1  quit smoking Took Zyban in 2007 and it did wonders! This time around things are NOT going so well. I am completely paranoid (I think someone is trying to break into my home, watch me in the shower) I have a massive short fuse temper and I’m depressed. I did some research this evening and have noticed that most people who are using this for the second time have issues. I’m going off this right away I can’t live like this, I have never been like this. Do not take it!!!! My husband took it for 7 days and felt like self harming himself, this stuff is BAD NEWS!!!! F 28 3 weeks
1 pill 1X day
1/28/2012
Email
 1  to stop smoking paranoid aggressive anxious lack of sleep weird thoughts of harming others This drug nearly cost me my relationship, its totally not safe, the side effect i feel if I have continued would have proberbly ended up with myself being locked up for hurting someone, seriously not good, I have never been an aggressive person and normally see the best in people, but this drug is terrible, M 43 3 weeks
150 mg 2X day
1/5/2012
 1  stop smoking migraines, dizziness, paranoid, no sleep, no libido, agressive, listless, no emotion, zombie, shaking, cold sweats. Disorientataion, forgetfull This product should not be on the market. Zyban nearly ruined my life.It has taken me more than 2 weeks to recover from the side effects of zyban. I have had the most excrutiating migraines that have led to nausea and vomiting. I have experienced cold shivers and cold sweats to name a few of the symptoms I experienced. There were only two side effects listed that I did not experience. Do not take Zyban it will ruin your life or kill you(suicidal) M 33 2 weeks
150mg 2X day
10/9/2011
Email
 1  Smoking Cessation I took Zyban (bupropion) over six months ago to quit smoking. I relapsed about six weeks ago after some significant stress in my life. About two weeks into this last round my throat became sore to the point that I saw the Dr. Negative throat culture but Doctor felt something going on-extremely swollen glands, small lesions on tonsils. Gave me Z-pac-no help. It never dawned on me until 2 days ago that my sore throat coincided with starting this drug. My throat was constantly, excruciatingly sore for 6 weeks!! I quit the Zyban and within 24 hours my sore throat was gone I also had vague symptoms such as sexual dysfunction, short term memory loss, chills, cough, headaches F 39 6 weeks
75mg 2X day
9/4/2011
Email
 1  to quit smoking DID NOT alter my desire to smoke. Matter of fact I felt obsessed about smoking, more than prior to meds. Severe anxiety, internal tremors, shaking, depersonalization, fear, paranoia, racing thoughts, insomnia, nausea, loss of appetite, feeling completely CRAZY and unstable , crying outbursts, anger and violent. Short term memory loss, severe. Headache, sore throat, got a sinus infection, chills. note: took 1 x 150 mg for 3 days, then upped to 2 x 150 mg per day (not at same time). First day I felt a bit weird, my body started twitching and I could feel my pulse all over my body. I figured it was tolerable. Same symptoms for 3 days while on one pill/day, with added jitters, and some feeling of anxiety but was tolerable. After 3 days still not feeling any change in smoking desire. On day 4 I upped to 2 pills/day (one early, one later) and the anxiety became tenfold. I slept 3 hours in two days. The only way I can describe what came next was " a whole lot of crazy". I felt like I've lost my mind, unsure of everything. Feeling completely like I can't get through the next minute, exasperated. On the last day I took this med (day 6) I took only 1 pill as I thought it might lessen the effects, and it was not any less, I was still crazy crazy crazy. I was terrified like I was trapped in a bad place and could not get out. My whole body was twitching, shaking, headache, nausea. The thoughts would not slow down, just on overdrive for everything. Today being day 7 I am not taking any more of this medication and I feel a little better today but still feel some of the effects. I feel more rational of mind like my real true self. Yesterday I felt like it was someone else in control and it was SOO bad, oh so bad. I had a lot of struggle just getting through every moment of the day yesterday. Still craved cigs whole time. Will try patch next. F 42 6 days
150-/300 2X day
8/5/2011
 1  Quit smoking Ringing in the ears (Tinnitus). An extremely stiff neck (needed a massage to release tension). My face felt like it was sun burnt and skin peeled off. Hives on my neck and shoulders. De-personolised feeling....agitated, very depressed. Aching feet. Insomnia, nightmares...the list goes on!! On the positive side I think that taking the Zyban suppresed my cravings for a ciggie, and I felt ok for about the first 3 or 4 days, then I stepped up the dose to 2 x 150mg per day after a week, this is when the side effects really kicked in. I thought maybe it was just me reacting to this drug, but obviously not!! I stopped taking the Zyban after 3 weeks, as I felt so bad....this should be a happy time having kicked a 40 year habit, but I felt worse than before I quit. The good news is I have been ciggie free for a month now, and slowly feeling better in myself. I read on the net that it takes a week or more for the drug to clear itself from the body once stopped. I would be reluctant to recommend taking Zyban. M 55 3 weeks
150mg 2X day
7/28/2011
Email
 1  to quit smoking several bouts of aniety, till had extreme heart rate increase, fainting feeling, tingling in entire body for over 20 minutes, called ambulance went to hospital for 4 hrs had tingling. Took 4 days to get out of my system, i have not smoked in 15 days now, but not touched the Zyban again. have spoken to several people who have had very bad side effects including seizures, shingles from the aniety also! Zyban, i want my money back, this is a very powerful negative drug as far as im concerned, yes so is smoking, but trust me quit cold turkey its the best way obviously!! Dont touch this drug, its powerful and will mess with your mind/ body. M 36 21 days
150 MG 2X day
6/10/2011
Email
  

ZYBAN  (BUPROPION HYDROCHLORIDE):  This medication is used in combination with a stop-smoking program (e.g., support group, counseling) to help you quit smoking. Bupropion can decrease your nicotine withdrawal symptoms (e.g., irritability, anxiety, restlessness) and your urge to smoke. Quitting smoking decreases your risk of heart and lung disease, as well as cancer. This medication belongs to a class of medications known as antidepressants. It is not known exactly how bupropion works to reduce smoking urges. It may work by restoring the balance of certain natural chemicals (neurotransmitters) in the brain. Discuss the risks and benefits of this medication, as well as other ways to quit smoking (such as nicotine replacement treatment), with your doctor.   FDA Approval Date: 1997-05-14 (Sources: U.S. Centers for Medicare Services, FDA)

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