ZYBAN Reviews (BUPROPION HYDROCHLORIDE)

Average Rating: 3.2 (580 Ratings)

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 ANTIDEPRESSANTS SMOKING CESSATION AIDS UNCLASSIFIED

 Type: Brand name discontinued; available as generic

  

ZYBAN  (BUPROPION HYDROCHLORIDE):  This medication is used in combination with a stop-smoking program (e.g., support group, counseling) to help you quit smoking. Bupropion can decrease your nicotine withdrawal symptoms (e.g., irritability, anxiety, restlessness) and your urge to smoke. Quitting smoking decreases your risk of heart and lung disease, as well as cancer. This medication belongs to a class of medications known as antidepressants. It is not known exactly how bupropion works to reduce smoking urges. It may work by restoring the balance of certain natural chemicals (neurotransmitters) in the brain. Discuss the risks and benefits of this medication, as well as other ways to quit smoking (such as nicotine replacement treatment), with your doctor.   FDA Approval Date: 1997-05-14 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Age oldest to youngest.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

Page: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29


RATING  REASONSIDE EFFECTS FOR ZYBANCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  Quit smoking Very effective in diminishing craving; have noticed slow increase in time each day, before I need to take it. Exacerbated slight hand tremor, to point where whole arm shaking. And a marked loss of power to throw. Dr recommended back on to beta blocker, when shaking is bad. M 72 7 days
150mg 2X day
10/28/2010
Email
 5  Quit smoking Twenty years ago. A four week prescription followed by an other4 week prescription. I stopped smoking instantly, maybe because I really wanted to . The side effects were waking up at 4.20 most mornings and I became paranoid and my wife threw the last 2 weeks tablets away. The job was done by then. I have had absolutely no cravings since giving up. M 67 8 weeks
?? 1X day
8/10/2020
Email
 5  Smoking cessation Slightly dry mouth, no other effects noticed by me, however adult daughter said I was "flat" and lacking ususal oomph.I should add that I did lose a little self confidence but only for about three weeks. After smoking for almost 50 years, and getting through 25-30 cigs per day, and after three previous failed attempts to quit(patches, Hypnosis, etc)this is in my view a wonder drug. I took 1 tab daily for 3 days, then 2 tabs daily, am and pm and smoked my last cigarette on the 7th day. I had absolutely no cravings from day one of stopping. My Dr. had prescribed 3 months of Zyban, I stopped taking it after 2. i am now 18 weeks smoke free and will never smoke again. I see people smoking and think they look weird and wonder why they do it!! My daughter says my oomph is back-I never knew it had gone!!. As far as I am concerned this is a wonder drug. F 66 2 months
cant recal 2X day
10/27/2010
 5  Quit smoking Vivid dreams that were not at all unpleasant. A bit of dry month. I wish I had taken this before I stopped smoking. I quit cold turkey for two months after 40 years of smoking. I soon had a serious case of insomnia that led to major depression. After 10 days on this drug, I started sleeping OK, and was more or less functional. That's on 150 mg. That was enough to do the trick, so I didn't up it to 300. M 65 2 months
10/17/2008
 2  To stop smoking I have stopped smoking but have been extremely depressed and feel like running away. I don't think this is missing the cigarettes as much as something in the drug itself. It is scary sometimes. Just really down and out from this but must quit smoking. F 65 4 weeks
6/17/2004
 1  to quit smoking Experienced lack of sleep, waking every hour, quit after two weeks,started the treatment in November 2004, in March 2005 noticed hair loss, by April holes appeared all over scalp - Dr diagnosed Alopecia - no cure and not known why it occured! within 3 months I lost all the dark hairs on my head and only very fine white hairs remained, I am 65yrs old and did have greying temples, however, my hair has changed it's texture from a thick dark brown colour to snowy white and is very thin and fine in texture. I have not beeen stressed and can find no other reason than that Zyban caused this dramatic effect.Would be very interested if anyone out there has experienced the same problem. [email protected] It may work for some but it did not work for me, I am a snowy white haired male now and my friends do not recognise me! M 65 2 weeks
7/19/2005
 1  Stopping Smoking Agitation, memory loss, complete change of personality, angry and depressed most of the time. Constantly arguing with my husband, tired all the time. Nausea, loss of appetite. This is a dangerous drug. I have stopped taking it after only 5 days and will look for other ways to stop smoking. The possible seriousness of side effects are not properly explained. This drug should not be on the market!!! F 65 5 days
150mg 2X day
3/18/2011
Email
 4  to quit smoking shakiness - constant buzzing in my head - quit taking it after 5 weeks and still have the buzzing 8 months later F 64 35 days
6/10/2004
 5  stop smoking I have been a smoker for 40 years. Struggling to quit for 20 years. I took Zyban 6 years ago and after 3 days had lost interest in smoking. Never smoked since. Cannot remember side effects they cannot have been that serious HOWEVER, I had a serious episode on the last day of the treatment. I became enraged at a neighbour who had been giving me a hard time for 5 years and I went in his garden and destroyed it, like the Incredible Hulk. Next thing I know, I wake up in bed with total memory loss of the last 20 minutes. I have a question. SInce I quit smoking with Zyban, (6 years) I have been a different person. No enthusiasm for life , no interest in doing anything. I used to be very active, I now spend my time reading and playing with computer. Not depressed, just going through the motions, without any real motivation. Is it possible that ZYban has permanently affected my brain? affecting the reward centres ? Anyone with the same experience, months after quitting with Zyban ? ALso a message to all of you who feel depressed. I have stopped smoking many times, cold turkey or with patches and everytime I would feel very angry. Within days I would hate my life and everyone in it and feel suicidal. It is the nicotine withdrawal. No Zyban. Talk to your GP. Get antidepression pills. Nicotine addiction is very serious and there are a lot of withdrawal side effects -physical and emotional. You are not being a sissy by getting help. F 63 60 days
1X day
12/24/2011
Email
 5  smoking chronic insomnia, increased appetite, vivid dreams. After smoking for 44 years, Zyban allowed me to give up smoking with no cravings at all.On day 36 and 10 days to go.Good thing I'm retired as I'm tired all the time- but it's well worth it! M 62 36 days
2/27/2007
 1  stop smoking unable to sleep stomach problems I took Zyban 8 years ago - and I still have problems sleeping - so much so my Dr has prescribed a mild sleeping pill to enable me to have 5/6 hrs per night so I can still keep my job. F 62 14 days
2X day
7/20/2010
 1  To quit smoking Stroke & Siezure Lost 5 years out of my life. Left me with a siezure disorder, panic disorder, double vision, heart problems and numberous other life-threatening disorders of the autonomic nervous system. Taking this pill is like playing Russian Roulet. F 62 9 days
6/12/2005
 5  to quit smoking vertigo, dry mouth, constipation, anxiety, weird dreams Zyban was a miracle. I used it to quit smoking 13+ years ago on the recommendation of my doc. the first week I experienced a lot of side effects, including anxiety around those side effects, but a friend who had taken Wellbutrin previous to my treatment assured me that the side effects would lessen once my body became acclimated to the drug, and convinced me to give it a week to 10 days. My directions had been to set a Quit Date but to continue smoking, and begin taking the medication. At around Day 3 or 4, my cigs started tasting strange... kind of like when you smoke a brand that isn't your own brand. I started smoking less and less as the cigarettes didn't really appear to be doing anything... they tasted bland and flat. By Day 10 (my Quit Day), I basically had lost interest in smoking. That was in March of 2002, and I haven't smoked since. I should add here that I had a very strong intention to quit smoking. I wanted to become a non-smoker after watching my father die of emphysema and my mother several years earlier die of acute pulmonary disease and pneumonia which she did not recover from because of her smoking. I had smoked for 32 years. This drug saved my life. F 61 30 days
150mg 2X day
10/3/2015
Email
 4  Stop Smoking After 16 days a nettle rash appears on chest and back, not too annoying and can live with it. Always a pill stuck in throat feeling, thats about all. I have actually managed for the first time ever to resist having a cigarette for several days and still don't need one. Used in conjunction with smaller patches it seems have the desired effect. I will now try weaning myself off both Zyban and patches M 61 16 days
2/10/2005
Email
 1  Quit smoking I had appearing a rash on my penis. It was literally raw. I went to my doctor and was treating me for some kind of burn . I figured out it was not external but internal. Once I stopped taking it, I began to heal. I even contacted the FDA to let then know of my adverse reaction to this drug. M 60 7 days
30mg
7/10/2013
 2  Depression I originally took Prozac as an anti-depressant, as I had stopped, smoking, drinking, drugs, the whole lot.. I knew there would be withdrawals from these things, but the Prozac didn't work and made me feel weird.. My specialist then suggested I try Zyban bupropion in other words as an alternative I was very hesitant because I have trained my brain to be anti-drugs, but I gave it a go.. I was okay for about a week, but by about day eight or nine, I started to have very dry mouth, no appetite and extremely hard to sleep, and when I did sleep crazy, violent nightmares, extremely violent!!! I've been feeling vague and surreal, wandering around the house like a zombie.. Today is day 16 and I'm coming off them. I don't know if it's just me with antidepressants but this stuff didn't agree with me. M 59 15 days
150mg 1X day
1/5/2023
 1  quitting cigarettes Day 1 - Slight jumpiness during the day and at night trouble settling down. Day 2 - No desire to smoke. Had diahorrea. Could not sleep for hours. Day 3 - Diahorrea again. Began to twitch in bed again little sleep. Day 4 - Itchy anus, moderate rectal bleeding, again in bed very unpleasant twitching all night no sleep at all, spastic like twitching with arms and hands. After these experiences I stopped immediately. Can't imagine anyone accepting these side effects is it me that is allergic? I am not allergic to anything else and tolerate new things easily. Other meds include multi vitamins and slow release tramadol for pain. M 59 4 days
150 1X day
4/9/2011
Email
 3  to quit smoking Agitated, can't sleep yawning alot moody Have only 3cigg since my quit date September 15,15 F 58 1 months
10/17/2015
 1  Smoking cessation Extreme bouts of rage,awful,frightening feeling. I do not recommend this drug. I am quitting smoking without any meds...5 weeks without so far do not take this drug F 58 4 days
dont know 1X day
6/7/2011
 5  Quite smoking Slept better than ever. Used to awake at 3:30 AM and stay up. Now I slep to the alarm. It's great and the only real side effect is waking up during the night with a hugh erection (honest). Have taken it for 11 month and feel it's a god sent to my not wanting to smoke. M 57 11 months
11/3/2004
  

ZYBAN  (BUPROPION HYDROCHLORIDE):  This medication is used in combination with a stop-smoking program (e.g., support group, counseling) to help you quit smoking. Bupropion can decrease your nicotine withdrawal symptoms (e.g., irritability, anxiety, restlessness) and your urge to smoke. Quitting smoking decreases your risk of heart and lung disease, as well as cancer. This medication belongs to a class of medications known as antidepressants. It is not known exactly how bupropion works to reduce smoking urges. It may work by restoring the balance of certain natural chemicals (neurotransmitters) in the brain. Discuss the risks and benefits of this medication, as well as other ways to quit smoking (such as nicotine replacement treatment), with your doctor.   FDA Approval Date: 1997-05-14 (Sources: U.S. Centers for Medicare Services, FDA)

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