LUPRON DEPOT-3 Reviews (LEUPROLIDE ACETATE)Average Rating: 2.6 (110 Ratings)Filter ResultsCompare LUPRON DEPOT-3 with similar:
Type: Rx Drug
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Results are sorted by Satisfaction lowest to highest. Key to Ratings: 1=LOW (I would not recommend taking this medicine.) |
More on LUPRON DEPOT-3: Reviews Summary | Drug Safety Information
| RATING | REASON | SIDE EFFECTS FOR LUPRON DEPOT-3 | COMMENTS | SEX | AGE | DURATION/ DOSAGE | DATE ADDED |
| 1 | Endometriosis and Fibroid | Mood swings, crying spells, hot flashes, night sweats, hair loss, damaged hair, dry/scaly skin, acne, joint pain, muscle pain, hand and feet muscles lock up, indigestion, headache, fatigue, loss of libido, anxiety, back pain, weight loss/loss of appetite, heartburn. | I only got Lupron for my surgery to try and shrink a fibroid sitting against my colon. The doctor didn't give the whole rundown of side effects, just the hot flashes and that it's similar to menopause. I have crying spells out of nowhere and I feel like I've aged thirty years. I just hurt all over and want to take naps all day. I would've never had taken this had I known more or knew the side effects were this terrible. The kicker is I won't know if it worked until surgery - no progress radiology taken to see if it's actually shrinking. | F | 35 | 3 months 3.75 Mg 1X M | 10/25/2022 | 1 | Endometriosis | This injection I had as one single to help shrink my womb, to prepare myself for a full hysterectomy. Immediately the site of the injection rose into a large lump on my arm. Was told not worry about it. About 2 weeks later things started creeping on me. Weakness in legs, severe lumbar back pain, painful soles of the feet, fatigue. Five years on I've ended up in a wheelchair, pain and weakness and depression has destroyed my life. I worked as a care assistant for years. I miss my job and this has turned not just my life upside down, but my families also. Really think and get every last bit of information before having this injection. | F | 45 | 1 days 1 shot 1X day | 9/17/2020 | 1 | Endometriosis | Insomnia, headaches, depression and anxiety so bad I had to be put on antidepressants. Muscle pain, memory loss, body shakiness...you name it! | I just finished a three month round and still feel bad three weeks after stopping. If I could to back I'd never have taken it. | F | 29 | 3 months | 4/10/2019 | 1 | Precocious puberty | I had mood swings, massive weight gain, migraines, hot flashes, and I broke multiple bones. I had swelling and rash at injection site. This medication ruined my life. | I would never recommend this to anyone. | F | 21 | 5 years | 12/11/2017 | 1 | Endometriosis and ovarian cysts | 1 Bone pain in arms legs back hands etc arthralgia 2 Osteporosis 3 Muscle wasting 4 Collapsing 5 Bad dizzy spells 6 Memory problems (short term) 7 Bowel problems like colon inertia. I have ballooned in size because my bowels are not working even with the use if strong laxatives picolax sulphate syrup 8 Visual disturbances 9 Confusion whilst doing things example I was making tea for my husband and was feeding my cat at the same time. I put sugar in the cat bowl and Cat food in my husbunnd tea. It's like my brains not quite working right 10 shaking visually 11 narcolepsy type symptoms I fall asleep out of the blue while drinking,eating and in the middle of conversation. I do know from research I've done that it attacks your pituitary gland so messes with your hypothalamus and endocrine system | I'm disabled now my legs buckle and collapse. | F | 39 | 7 months 30 mg | 10/26/2017 | 1 | Misdiagnosed to treat Endometriosis | Vomitting, severe aches and pain-including bone pain, hot flashes, worsening of my reason for the injection-pelvic pain due to adhesions, migraines and aura in vision, night sweats, irritable, fatigue, painful tongue-burnt sensation, insomnia. Note: these are all normal side effects according to the clinical trials. | Fortunately my side effects slowly faded months after the 3 month injection was given. Except my migraines-they are horrible, and everyday I have dark specks in my vision (had it checked, its normal for people with migraines). A brilliant neutologist with a PhD explained that Lupron goes to the nucleus of the cell, changing it forever. After MRI of my brain and eyes, etc. My permanent effect from Lupron is migraines. Something I never had prior to that day... If I could take any day back I would take the day I said yes to Lupron injection and read the clinical trials. Also I don't have Endometriosis, it was a misdiagnosis. I have Adhesive Disease.. | F | 30 | 3 months | 8/8/2017 | 1 | Endometriosis, fertility | Hot flashes, heavy periods (when I shouldn't have them), migraines, bad cramping, IBS, stomach bloating, weight gain, insomnia, lack of energy, dizzy, nauseous, shaky, off vaginal smell, lack of sex drive | I was put on this after my laproscopy surgery to help my chances of future fertility and also help keep it from growing back as quickly. My gut told me not to get it aND I did anyway in fear of what would happen if I didnt. I am supposed to get a second 3 month dose this month and I cancelled it. Horrible thing to go thru after expecting to be pain free for a while. | F | 23 | 3 months | 3/5/2016 | 1 | Endometriosis | Hot flashes and night sweats so bad, I showered 3 + times per day. Terrible Mood swings, horrible agitation, anxiety, crying spells, nightmares, insomnia. so busy dealing with the misery of the side effects, I have no clue if he helped | F | 44 | 1 times | 9/12/2015 | 1 | CPP | Fibromyalgia, TMJ, degenerative disc disease, bone weakness, muscle weakness, sciatica, hot flashes, teeth chipping, depression, migraines | We should have been told this was a chemo drug. This needs to be taken off the market and we victims should receive compensation for all past and future medical bills that relate to Lupron. | F | 15 | 2.5 years 22.5 1X M | 9/29/2014 | 1 | Endometriosis pain | Severe depression, anxiety, mood swings, short term and long term memory loss, 24 hour a day sweats, aggravation, no energy or motivation, pain came back within 2 months after my last injection. Horrible experience!!! | F | 34 | 6 months 3.75 | 3/28/2014 | 1 | Elevated PSA after prostatectomy | Hot flashes, depression, energy and muscle loss, fuzzy thinking, memory loss, forgetfulness, extreme fatigue. I work full time and never had any of the above problems until after the injection that will last another three months. Google lupron petition. It is before congress to ban this horrible drug. | M | 72 | 3 months 3 | 7/3/2013 | 1 | Prostate cancer | weight loss, fatigue, MDS, loss of hearing, heart attack and death. | I am the wife. It is my opinion that my husband died because of the Lupron Depot injection. | M | 82 | 2 months 1X M | 5/10/2013 | 1 | Endometriosis | Pain, and crazy mood swings. | I had the 1 month injection given to me 2 days ago due to supposed endometriosis, aka pain that wad only getting worse, periods getting heavier and more painful, and experiencing painful intercourse for nearly a year. I just had my 2nd child 3 months ago, was on the pill, which only made my mood and periods worse. Finally an ob recommended I try this instead of "different positions and more lube and throw some Mrotin in the mix for the pain." first of all, due to a stomach condition I can't even take motrin and right now I am in so much pain, and I have been alternating between pure rage and complete hopelessness...not to mention yesterday I had the first migraine I've had in years, and fluid retention...and yet they won't do another surgery. I've already had one ovary removed due to a lot of good sized cysts, and have 2 beautiful children(and 2 miscarriages), and am so Done with dealing with this...I am feeling very lied to by the ob and would never wish this hell on anyone except maybe a serial killer or something. Please tell me it gets better or at least some advise on what to do... | F | 23 | 3 days 3.5 1X M | 8/24/2011 | 1 | Pain, endo? | Had an emergency hysterectomy after the birth of my son 19 years ago, have had trouble ever since, it's taken them this long to do anything!!! passing out with the pain, only one ovary, adhesions, leg pain, bowel problems | I was great at first, even though the mood swings were awful and I was very very tired (I have narcolepsy and it seemed to make my symptoms there better too) but started getting chest pain within about 8 months and my blood pressure shot up!!..and stayed there! Massive weight gain, my hair has thinned a great deal ( I have very very long hair so it has made a big impact) The hot flushes started to get unbearable, I honestly felt that I would literally drop dead of heat exhaustion, dramatic but true! Suicidal!!!Lost all my confidence, have become a recluse..cannot lose weight no matter what I do, I'm so tired. Developed a fistula so now a colostomy is on the cards, the doctors can't tell me if it's connected or not. I just feel like a lab rat frankly so I'm not having the shot anymore, Totally fed up and have no life now. The oestrogen add back was the worst point. I was literally barking at the moon and I don't feel that I was monitored enough by the doctors. My life has ground to an abrupt halt completely and all the tiredness, hair loss, depression, it's all been for nothing. I wish I'd never been put on it. I will never go back on this drug, ever! I'm better of with nothing but my own oestrogen, at least the symptoms were only monthly rather than all the time! I don't believe that the doctors know enough to prescribe this drug to women. I studied medicine myself when I was younger and my treatment over the years has just been absolute rubbish! | F | 42 | 1 years 1X M | 1/25/2011 | 1 | Adenomyosis | I've suffered with adenomyosis, probably for 35 years. After years of being on various low-dose types of the Pill and Depo Provera, nothing was very effective. With Lupron Depot, I had hot flashes, cold chills, and sweating all day. I since decided to have a hysterectomy. I developed pain in my neck, arm/leg joints, and hips five months after my first (and last) injection. The joint pain has been getting progressively worse. | I did not have joint pain prior to taking this drug. The 11.25 dosage is to be taken every three months. Four months after the injection, I had a hysterectomy (with my ovaries remaining). I'm not in menapause and am still ovulating. Prior to surgery, I was in excellent health, with no family history of arthitis. I am very strong and was very mobile prior to surgery. I'm taking it easy, as it has only been five weeks since my surgery, but I walk and move around and eat and sleep well. But I'm surprised that the neck and joint pain started after the surgery (five months after the Lupron Depot injection). The hot flashes and sweats have been greatly reduced since I started taking sage leaf extract a couple of times a day. But I'm concerned that the drug has affected my immune system, and I hope it hasn't triggered an auto-immune response in my body. | F | 47 | 3 months 11.25 1X O | 12/17/2010 | 1 | Endometreosis | Hot Flashes, mood swings, abdominal cramping, diarrhea, migranes, vision changes, decreased sex drive, nausea, vomiting, light-headedness, | I have only been on this medication for just over 2 months, first month went fine no problems besides the hot flashes... if those were the only side effects i could deal with it. Directly following the second shot however, the side effects got extreamly worse. I foolishly didnt do any research before accepting this shot, I recomend that anyone being told that they should go on this, DO RESEARCH! Endometreosis is a very common diagnosis among women, almost 60% of women. I dont believe this drug has helped me at all. I believe it has made things worse. I have missed several day's of work because i couldnt function at all. The abdominal pain, nausea, hot flashes, dizzy spells, fainting, back aches, trouble sleeping...It felt like i had the flu for a month straight. ITS REDICULAS! i think all health care providers should definatly have an in depth conversation about the side effects with their patients they plan on giving this shot to. If the patient dosent mind having all these side effects on top of the endo-pain... go right ahead.. but personally I will never take this shot again! It hasnt helped, just made everything worse! | F | 23 | 2 months 1X M | 10/18/2010 | 1 | PROSTATE CANCER | In 2007 I had a radical prostatectomy. In 2009 my PSA went up. Dr recommended Lupron depot. Did not inform me of possible side effects. Now I have no muscle strength, very poor endurance, hot flashes, very poor sleep, memory loss, very poor concentration, irritability, bouts of extreme depression, vision changes, and PAIN in legs. | When I went back to Dr he said my PSA was lower and would not need another injection. Stated I would never take another injection. This medicine has destroyed my life. I have been a paraplegic for 23 years. My life has gone from being independent to depending on others. I cannot make transfer into my car so now will have to buy van with lift. The pain in my legs seems to be bone pain mainly is in my left femur which has had no feeling for 20+ years. Due to the muscle weakness I have fallen and fractured two bones in calf. Dislocated a finger and suffered a torn rotator cuff and head trauma. THIS MEDICINE SHOULD NEVER BE GIVEN TO A PARAPLEGIC WITHOUT AN EXPLANATION OF POSSIBLE SIDE EFFECTS! I was given the shot Sept 1, 2009 and went to my 40th class reunion on Nov 21, 2009 and barely remember any of it. | M | 59 | 1 times ? 1X O | 7/16/2010 | 1 | Ovarian Fibroid and Heavy Bleeding | Severe weight gain, horrific hot flashes, mood swings which effected my everyday life, severe depression, joint pain and frequent, long lasting headaches. | I was happy with this medication on my first go around, I used it for a little over a year and it did what it was suppose to do, decreased pain, stopped my bleeding. After losing insurance coverage I had to go off this medication for about 2 years during which the pain and bleeding returned worse than before. I was able to get back on the shot for about 1 1/2 years during which the side effects were awful. I continued the shot because of the fear of the pain in my pelvic region returning and the uncontrollable bleeding. I have been off the shot since Feb and all my old symptoms are returning. This time I do believe I will seek a surgical treatment versus Lupron Depot! | F | 30 | 1.5 years 1X M | 6/6/2010 | 1 | Endometriosis | hot flashes & sweating bad at night, decrease in sex drive, mood swings | I would never take this shot again. I took my last shot in February and have yet to have a period. My pain was not bad at all and this treatment was not worth it. My endimetrosis was discovered when i had a cyst removed. He said it was a light case but went ahead and put me on a 4 month shot. One one month and then three the next month. If i had to do it all over i would not. When should i expect a period if anyone knows? | F | 30 | 4 months 4X O | 5/17/2010 | 1 | Endometriosis, Heavy periods | Tingling under skin, severe migrane, spots in vision, emotional meltdowns, anxiety, hot flashes, memory loss, confusion, anger, mood swings, weight gain, joint pain, strange shooting pains, loss of period, extreme fatuige, heart palpatations, rashes and skin problem, darkening of skin on face like above upper lip and under eyes, insomnia | On January 25th I had a lap for endo. On February 12th I had a lupron depot shot(3month).I was told the only way to keep endo from coming back for 5 years is taking the lupron. The third week was hell.............I started to have panic/anxiety attachs. I scaring my family. Then came the hot flashes, ever 15 to 30 minutes!!!horrible. I still have not started my period and I am coming up on 6 months. I WILL TELL YOU FROM MY EXPERIENCE THIS DRUG IS EVIL AND SHOULD NOT BE USED! THE SIDE EFFECTS ARE FAR WORSE THAN WHAT YOU COULD EVER IMAGINE. MY HUSBAND AND I ARE GETTING A DIVORCE AND I BLAME IT ON THE SHOT!!! IF YOU HAVE A FAMILY DO NOT TAKE THIS MEDICINE. MY 11 YEAR OLD SON AND I ARE VERY CLOSE AND IT IS HARD FOR HIM TO UNDERSTAND THE SHOT AND WHY I AM STILL HAVING PROBLEMS. NEVER EVER TAKE THIS SHOT!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!! SOME DAYS I WONDER IF I WILL EVER BE MYSELF AGAIN OR HAS IT ALTERED MY CHEMISTRY FOR GOOD???? THERE IS NOTHING THE DRS OR ANYTHING I HAVE READ ON THE INTERNET ABOUT HOW LONG IT STAYS IN YOUR SYSTEM OR HOW LONG IT WILL BE BEFORE I FEEL LIKE MY SELF AGAIN..............BE CAUTIOUS ABOUT WHAT YOU LET BE PUT IN YOUR BODY. GOOD LUCK TO ALL AND BELIEVE WHAT IS WRITTEN IN THESE COMMENTS I DID NOT AND AM PAYING THE PRICE, MY LIFE HAS BEEN STRIPPED FROM ME AND I DONT WANT THAT TO HAPPEN TO ANYONE ELSE | F | 30 | 6 months | 8/3/2009 |
LUPRON DEPOT-3 (LEUPROLIDE ACETATE): Leuprolide is used to stop early puberty (precocious puberty) in children. It helps to delay sexual development (such as growth of the breasts/testicles) and the start of menstrual periods. It also helps slow down early bone growth to increase the likelihood of reaching normal adult height. Leuprolide works by decreasing the amount of sex hormones that a child's body makes (estrogen in girls, testosterone in boys). FDA Approval Date: 1997-03-07 (Sources: U.S. Centers for Medicare Services, FDA)