Drug Ratings for EFFEXOR XR

Average Rating: 3.1 (2057 Ratings)

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)   

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 5  Depression, Anxiety, Social Anxiety Missing 1 dosage can lead to uncomfortable withdrawal effects (called "brain shivers). Causes a mild case of erectile dysfunction. Causes night sweats. Took Effexor XR for around a year and it helped even with the first small dosage. Was happier more frequently and less anxious in most situations. Depression was practically non-existent after a few months (along with the help of therapy). However, last few months with Effexor XR became difficult for side effects mentioned (took Wellbutrin to combat the side effects and it did it well, but was risky and dangerous due to a higher risk of seizures from high amounts of serotonin). Despite the side effects, would recommend Effexor XR as its effective and its side effects are not as bad as other anti-depressents. M 22 1 years
300mg 1X D

 1  Depression Dizziness, nausea, headache, and disorientation/confusion upon missing a dose. Caused insomnia and nervousness no matter what time of day that I took my pill. I am currently going through withdrawal and am experiencing nausea, headaches, brain zaps, body aches, hallucinations, diarrhea, and extreme depression/feelings of hopelessness, although I am handling the latter well with new medication. F 22 4 months
 5  PAIN sweet more, and you do not want to start it and then quite taking it, or take it and forget it when going out of town. But besides that , what a huge difference it makes on my pain , I had a doctor , want to try this , I trusted her and I am very glad I did.... Have taken it for 15 years, if you have any questions please ask.Thanks M 53 15 years
150 1X D
 5  Depression and panic attacks I have been on numerous ssris including celexa, Zoloft, Prozac and others. I didn't have any prominent side effects on most (excluding Zoloft, terrible for me) but with that said, they helped mildly, they took off the edge. I was on Prozac for about three years but after moving to northern Alberta from southern, the winters became harsh on my depression. I had it increased but still no luck, Prozac was just no longer cutting it. It was during my finals that I visited a walk in clinic in hopes to get another increase. The doctor said that i most likely had sad and decided to change my meds. My mom being an RN was furious at this, she couldn't believe that he would change my medication without knowing me or at least consulting with my psychiatrist (back home) I kept to my Prozac until the end of my finals. I did research online and came across so many haunting reviews and even debated not taking it at all. The first day after taking it, I had headaches and I'd wake up to vision issues this lasted about 14 days and they intensified when tweaking with the dosages. I am happy that I stuck to this medication, within two month I began to feel what I imagine others describe as happiness, something I had so rarely experienced. My panic attacks had improved tremendously, I am now able to drive within city limits without feeling anxious. My outlook on life has completely changed, I'm the happiest I have ever been. Its trial and error, best of luck to you all. F 20 6 months
150 mg
 4  anxiety attacks lack of sexual arousal, low libido I have been taking Effexor XR for about 15 years. I love it. My dosage seems low compared to all the comments here. My doctor started me on 37.5mg and then upped it (he said to tell him when I felt like it was working). At 75mg I felt NORMAL for the first time in my life. Now after taking it for almost 15 years I have recently had 2 anxiety attacks and loss of mental concentration. I am going to ask my doctor up my dose to 150mg. The side effects are well worth the normalcy I feel. It has allowed me to function better in my career and in my family. I have no doubt that without it I would not have been able to work in my current job or have the healthy relationship I have with my children. F 56 15 years
75mg 1X D

 4  depression M 60 12 years
75 MG 2X D

 1  Depression and anxiety Severe withdrawal symptoms. Dizziness and "electric zaps" to the brain. M 39 1 years
75 MG
 4  I worried about things Everything was great on it...trying to wean myself off of it is a different story. I have tried twice and I get so dizzy that I can't function. Needless to say, I'm still on it. So afraid to try quitting it again... F 38 2 years

 4  Depression While I have been on Effexor, I have identified side effects like asexuality - also, other sexual side effects; including: Ejaculation problems, and reduced climax intensity. There are also more mild effects on my sleep - Night sweats, and vivid dreaming. I do not mind these as they are not bad enough to be particularly unpleasant. M 18 1.5 years
300mg 1X D

 1  depression, chronic pain Mood changes, more depressed,hostile thoughts,cold sweats,vomiting, agitation,aggression,trouble sleeping,crying spells, mind wanders of into lala land. Suicidal thoughts, very scary. Do your home work on this dangerous drug before taking it. It may work for some folks, the complaints i have looked at are bad. FDA should ban this drug. F 57 6 months
150-37.5 2X D

 1  Anxiety Nausea,panic attacks, no sleep, loss from reality, headaches,shakes F 22 1 days

 3  depression and anxiety Complete loss of sex drive. Unable to maintain an erection. Dry mouth and constant "clinching" of my leg muscles. It's driving me nuts The med did help significantly with my depression and anxiety, but the side effects outweigh the benefit of the drug. Dr prescribed 300mg of Welbutrin in addition to the Effexor to offset the side effects. No improvements. Just jumpy now. M 41 2 months
150 1X D
 4  Clinical Depression Loss of motivation. F 62 7 years

 4  menopausal symptoms reduction in number of hot flashes. I was begging for return of my hormone therapy and doc suggested this. It works. My problem is that after a hospitalization I had "depression" listed on my problem list because why else would someone take an anti-depressant? Oh well, it works. F 62 9 months
75 1X D

 3  Depression/Anxiety Anyone experience odd side effects where this completely 100% wipes out *ALL* types of "Anxiety"---meaning "Even the good type anxiety" (you know "Good type" meaning that you're properly rushing to make it to an appointment, etc. My friend years ago, his side effects were so severe (He moved homes/states--which is "depressing" for him anyway. However, on 300mcg of effexor. ended up having his car repossessed and this is a very "High Functioning" individual (ie. not abusive with Finances,etc.) He just completely 100% lost motivation. (there was a mix up in mail, thus 2-payments-1 not mae at move-another not forwarded. Anyway, I am now having the same side effects. Laughing, I even tell my friend I've lost motivation to even go to the bathroom. When I feel I need to go, I'll be like "Eh, I'll get to it in a few hours". Anyone else? LORD! Cymbalta was even *WORSE* Effexor I can at least go walk the dog when he wants out. Cymbalta, I lost *ALL* 100% *ALL* motivation. Let be be clear, this was *NOT* depression (I've had varying degrees my adult life, so I know that feeling and I Know "Anxiety". also know there is "Proper" Anxiety as well . Again, makeing sure you "hustle" to make an appointment on time,etc.etc. (Anxiety wrong word but "Motivation"). Anyway, curious if others have this "Issue". One could argue well, the drugs working. Yeah, but if I take 1/2 my dose, does not work at all. Anyway, looking for similar experiences. What you did to overcome. M 40 5 years
150mg 2X D
 1  Anxiety and Depression Started off feeling great, a few months later- terrible! Totally numb, couldn't summon any feelings, even toward my partner. Put on a huge amount of weight. Constantly constipated. Not motivation. Exhaustion that was so bad I couldn't get out of bed. Panic attacks came back. Am now tapering off and it's hell. Wish I never started F 25 5 years
 1  agoraphobia, panic, and depression Severe diarrhea, dizziness, nausea, dehydration, unconsciousness. I only took one dose of Effexor. It made me sick within 6 hours of taking the pill. I spent the entire night in the bathroom, and my sister found me on the floor the next morning. I remember thinking I should call 911 at one point, but I didn't have the strength to get to the phone. And then I decided I didn't want to go to the hospital anyway; I was fine with dying on the floor (it definitely altered my mood in a bad way). I was in bed for a week afterwards. It was the first antidepressant I had ever taken, and the experience was so horrible and frightening it took over a year for my doctor to convince me to try something else. F 34 1 days
75 mg 1X D

 3  depression anxiety lowered sex drive, could have been better for anxiety. Ok for dealing with a full blown depression. M 45 6 years
75-150mg 1X D

 5  Social anxiety disorder Dizziness the first 2 days and feeling yucky in the evening, vivid dreams, yawning, dilated pupils, night sweats for a few days. Moved from paxil to effexor. I immediately stopped the paxil and started the effexor -- no paxil withdrawals. Paxil had made me a sleepy hungry slob who could not have an orgasm (It took about an hour to ejaculate, therefore getting off sexually was tiring, frustrating, and not practical). Effexor has been excellent. Much more effective for me than the paxil was, and without the horrendous side effects. I hear some people find effexor too activating to be used for anxiety. In my case, I disagree with that very much. This med has blasted SSRI's out of the water with regards to side effects and symptomatic control of anxiety in social settings. I am not emotionally flat nor zombie-like on this med. Keep a few caps stashed away somewhere. You have to be responsible while taking this med. Keep to the routine. It's like the insulin of psych meds, you do not want to be caught without it on short notice. The withdrawals can and will be a nightmare if you are not careful with this med. M 22 1.5 months
150 mg 1X D

 1  Depression My blurb here is based on 2 experiences - the first was when I forgot my medication at home while travelling on business. The other is when I discontinued the medication. This medication is terrible. My new psychiatrist said that this stuff was a "killer." A killer.... can you beat that with a stick. When I forgot my meds at home on a business trip I felt like I was going to DIE. I was anxious and paranoid, felt like my skin was peeling off...pretty much the worst plane ride home EVER. After experiencing that I decided to discontinue the med shortly after. The next 3 weeks was TRAUMATIC. I experienced paranoid hallucinations (which I never had before), terrible anxiety BUT the worst thing were the "brain shocks" that would zap through my skull every 30-45 seconds. NO JOKE. It felt like someone stuck a car battery charger against my head then turned it on. I don't recommend this medication at all. Pls look for an alternative. M 35 2 months
175 1X D
 3  Depression & Social Anxiety Initially: Erectile Dysfunction, Decreased Cognitive Ability, Memory Issues, Sudden Weight Gain, Horrific Withdrawal Symptoms (vertigo, spinning room, nausea, light and movement sensitivity... lasted 2 weeks, was bed ridden) This medication is an effective anti-depressant. You can expect to have a 2-3 month lead in with annoying side effects. Every dose increase will bring those side effects back. Once my body had adjusted, all the side effects left me, and my mood was balanced and lifted. My social anxiety did not improve, but I believe I have a dopamine deficiency. Expect to be off work if you are coming off this medication. DO NOT miss a dose, DO NOT discontinue without speaking to your doctor and reducing doses slowly. You will regret it if you don't. Make sure this is something you want to take long term, as it is something you do not want to start and stop. M 26 12 months
150 mg 1X D
 1  Depression & anxiety Erectile dysfunction, disturbed sleep, less muscle tone, blood pressure problems, trouble concentrating and with fine motor movement, anger, violence, bad dreams, Took this after switching from lexapro because it caused ED. Doctor prescribed this, made it worse, much worse. Permanent ED. No morning erections. Feel very bad about life now and very alone. M 27 2 years
75mg 1X D
 4  Anxiety/depression Tiredness lethargy loss of libido but it did work wonders for my depression. M 67 1 years

 5  Depression, GAD, social anxiety Increased sweating I am a psychiatry resident, and I just want to say that all ratings from people who have taken any SSRI (Prozac, Paxil, Zoloft, Lexapro, Celexa, Luvox) or SNRI (Effexor, Cymbalta, Pristiq) for less than one month should be completely disregarded. In fact, this site should probably remove them. These meds take at least 3-4 weeks to work like they are supposed to. And yes, people get GI side effects and headaches (since serotonin is mostly in the nervous and GI systems), but these are typically worst on days 3-7 from starting or with a dosage increase, and they do get better. Increased sweating has been my biggest problem with Effexor XR. I have tried switching to Prozac twice (currently I'm on 40 mg of Prozac). The sweating is better for the most part, but I think Effexor was really helping to control my irritable bowel symptoms because it's kind of out of control at the moment (it makes sense due to Effexor's norepinephrine reuptake inhibition, which is the mechanism of the older tricyclic antidepressant nortriptyline that is often used for IBS and other chronic pain syndromes). I've been on varying dosages of Effexor (150, 225, 300 mg). I was doing really well on 150 mg for the past year but again I wanted to sweat less. I'm pretty sure I'm going to go back on Effexor despite the sweating. There are really no magic pills; generally patients need to weigh the benefits and the side effects (which generally improve or disappear). M 27 2.5 years
150 mg 1X D

 5  I was taking Effexor for anxiety I have dreams quite frequently. I sweat a lot and can be moody at times. All in all I think Effexor has changed my life for the better. People should give it more time to work. It takes 6 weeks for anything to feel any better. Everything has negative side effects you just have to weigh the pros and cons. I think Effexor is wonderful and I won't be stopping anytime soon. F 27 10 years
75 MG
 4  Depression/Anxiety Increased blood pressure, jittery, loss of libido, racing heart, irregular heart beat, consipation ... after about five months, horrible rash, hives and itching. I have tried several different meds in the past for my anxiety/depression. I seem to be very sensative to side effects. Effexor really seemed to help level me out and make me feel happy again and not worry so much. But almost immediately, my blood pressure went up and I became very constipated. Then I started experiencing a racing heart and occasionally would feel 1-3 'hard' heart beats every 5-10 minutes. After about 5 months, I suddenly broke out in a rash and hives on my chest, shoulders and neck. My face would become red, flushed and itchy and I'd itch from head to toe. Guess I need to try and get off this stuff and try something else. M 45 5 months
150 mg 1X D

 5  Sleep dis, menopause, mood swings None, maybe some weight gain I have tried other anti-depressants and could not tolerate Paxil, Prozac, and a few others. This one worked like a miracle. After a week I felt completely normal again. I was sleeping and I felt like my old self. I don't remember the exact dose I was on, but it was a low-moderate dose. After about 6 months I tapered off for another couple of months. F 48 9 months
50 1X D
 4  Major depression Weight gain Never ever try to come off cold turkey!! In the process of weaning off by the doctors orders. Tingling in feet, and that is it so far. I can't wait to be off of hs drug! It helped for 6 years, but the weight gain is really getting to me! F 40 6 years
150mg 1X D
 2  Depression, generalized anxiety Weight gain. Reduced mental clarity. Heightened emotions. Suicidal thoughts. Withdrawal is a btch. I was on 225 mg for a long time and then tapered down to 37.5 mg. Reason I'm writing this review today is that I was without medicine for 2.5 days and I'm in a dark and uncomfortable place. I ended up in ER twice because of Effexor withdrawal in the past. It may work short term but doctors need to be more careful in the cost-benefit analysis of this medicine. Also, in the event of misdiagnosis (as it was in my case), if you write this drug for a patient who is actually bi-polar, you'll intensify the manias (when most of the suicides etc. occur). M 31 3 years
37.5 1X D

 4  Depression/anxiety decreased appetite, sexual dysfunction, lightheadedness/dizziness (relatively mild). Most of these have improved but are still present. I started out at 75, then bumped up to 150, 225, and now 300 mg. I feel like 300 mg is a lot but I have had treatment-resistant depression and have been on SSRI's for a couple years so it's not bad. With SSRI's, withdrawals are not bad as long as you taper down. If you are on a high dosage and you cease taking it immediately that's very dangerous. Effexor is not "addicting" in the sense that a narcotic medication like Xanax is, but it does cause chemical changes in the brain (that's how it works) and the readjustment period if you stop taking the medication is considered "withdrawal". As somebody with a substance abuse history, SSRI withdrawals are a joke compared to alcohol or any other narcotic. You can't die from Effexor withdrawal lol. So far the medication has worked fairly well for me. I am finally able to get back to work and I have motivation to do things again. I have no major complaints other than the short half-life of Effexor (make sure you take this med at the same time every day, because withdrawals can kick in just from missing or being late with a single dose).' I also take Trazodone 150 mg to help me sleep and Buspirone 15 mg to help with sexual side effects. Please feel free to contact me if you have any questions or concerns about your experience with the med. 99% of side effects (except sexual) get better within the first couple weeks. Hang in there! M 22 3 months
300 1X D
 5  Panic Disorder with agoraphobia At first nausea, but that subsided. Also, a small increase in anxiety when starting the med. The only antidepressant that has helped me. I take it with Valium and propranolol, and got my life back! Best of all, I experienced no sexual side effects from this drug, as opposed to the others I've tried. M 26 7 years
150 mg 1X D

 5  anxiety/depression Lower sex drive This med saved me and my family. Debilitating anxiety, terrible insomnia brought me to the point of ending my life. Effexor XR worked practically instantly improving my ability to fall asleep. As my night sleep got better, anxiety went away. My Dr. telling me to stay on my medication, and I do not have a problem with that because I never want to go back to depression. May be I am just lucky, but I practically have no side effects. F 56 3.5 years
150 1X D
 1  anxiety Dry mouth, restless legs, fatigue and drowsiness. The worst part of about this drug is it eventually did nothing for my anxiety, and when I tried to discontinue it several times, I had rebound anxiety so bad I had to go back on it to relieve it. This was a vicious cycle that went on all four years. I would not recommend taking this drug or any SSRIs. They do not work and they are addictive, no matter what your doctor says. You will get hooked on them as bad as heroin or cocaine. It will be impossible to ever stop them. They cause brain damage like short term memory loss and dementia. All the SSRIs are bad. Don't ever start them. F 53 4 years
75 mg 1X D
 3  Depression Weight gain, emotional numbness, muscles sore, constipation, Restless Legs, do not even THINK about sex and memory loss that made me think I was getting dementia ( that runs in my family). I asked my Dr. to take me off effexor because of memory loss. He told me to take 1/2 tablet (75mg) for 2 weeks; then 1/4 tablet (37.5mg) for 2 weeks then 1/4 tab every other day for 2 weeks. I could not tolerate the every other day because of the "brain zaps" so I took 1/8 tab (18.75mg) daily for 2 weeks. I then stopped taking any amount and the brain zaps increased and I was a crying, sobbing mess! I cried at everything and at nothing! So...I am taking 1/16 tab (9.375mg) and it has stopped the brain zaps and minimized the crying spells. This is RIDICULOUS!!! Will I ever get off this stuff??? F 65 8 years
150 MB 1X D
 1  Depression,anxiety gained a lot of weight. I didn't wan't to miss a dose because withdrawl starts right away. I didn't realize I was gaining so much weight. It just started slowly coming on and before I knew it 3 years later I had gained about 30 plus lbs. I suggest trying almost anything before this, and if you do go on this drug be prepared for a living hell getting off of it. There have been a few that had minimal issues getting off of it but the majority including myself wen't through a special effexor version of hell. That possibility is my warning to anyone who wants to give it a try. Keep in mind the websites by the drug makers of effexor gloss this truth over. So look into it well before taking it because I sure didn't. Weaned myself off very slowly because I just wasn't getting enough good out of it and it was unpleasant if I was late taking my next dose or if I missed it for some reason. this is one med that you better not miss getting a perscription filled for. Finally got off this pill and lost 30 lbs over about a year without even trying. F 37 3 years
75 1X D
 1  Depression and intrusive thoughts Heart palpitations (beat at 140bpm) whole body numbness and weakness (couldnt lift my arms or walk without help) whole body tingling/burning, couldn't breathe or speak, felt like I was dying. Ended up in hospital. Stopped on day 5 and all symptoms went away. Do not take this drug!!!!!! F 21 4 days

 3  Depression Stimulation, Restless leg, tingling in legs and feet, nausea, Dizziness, mood swings, suicidal thoughts, aggression. M 20 30 days
37.5MG 2X D
 3  anxiety After beginning i had terrible nausea,sweating profusely,constipation,lack of sex drive. Trying to wean off now and my brain feels like its on a rollercoaster,im so irritable i feel horrible. This is my 2nd time on effexor xr and there Will NOT be a 3rd!! effexor xr and there willNOT F 29 2 years
75 mg

 1  Social Anxiety Debilitating knee pain (permanent), increased joint pain, bone pain, chest/heart pain, rapid heart beat, sweating, exhaustion & insomnia despite exhaustion, confusion & impaired cognitive function, increased anxiety. This drug caused permanent knee pain so severe that I can barely walk now about a year later just from the lowest dose taken for only two weeks. This drug is poison to most males, although it seems it works okay for females. If you are male do not take this drug! Instead take a benzo like klonopin for anxiety or if you have pain take something that is less experimental like vicoden or percocet. M 24 2 weeks
37.5 1X D
 1  Panic Disorder, GAD, PTSD Nausea, heavy heart beat, weakness, abdominal pain24/7 bloating, lightheaded24/7, shallow breathing,blurred vision24/7, increased thurst, servere sweating (expecially when nervious) ie: makeup would come off within minutes of putting it on. nightsweats (soking the sheets) chronic constapaion for (1.5 years) developed Tinitus too. Worst thing I have ever done!! It had affected every area of my life. Could not do 'normal' everyday life easily, as was ALWAYS PHYSICALLY ILL! Felt 85 not 25! I agree with the RN nurse above. Do not try this drug unless you have been chronic(years) and have try natural methods first (NO SIDEEFFECTS) The way God intened to help this. F 27 3 years
75mg - 225 1X D
 5  Major Clinical Depression Have taken for 13 years and is the only drug that has sent my depression into complete remission with the help of lamotrogine which I added about 4 years ago. Wanted to document the fact that I am otherwise perfectly healthy and fit, but have just had a low grade tumor removed from the base of my spine. Don't know if this was related to the Effexor or not. Will continue taking it, as it allows me to live a normal life. But wanted to let everyone know. Noticed in another post that someone also had a tumor in the pituitary gland. Have taken for 13 years and is the only drug that has sent my depression into complete remission with the help of lamotrogine which I added about 4 years ago. Wanted to document the fact that I am otherwise perfectly healthy and fit, but have just had a low grade tumor removed from the base of my spine. Don't know if this was related to the Effexor or not. Will continue taking it, as it allows me to live a normal life. But wanted to let everyone know. Noticed in another post that someone also had a tumor in the pituitary gland. F 43 13 years
225 1X D
 1  depression Alcohol binge drinking. M 34 8 months

 1  Major Depression Dilated Pupils Didn't do sh*t. I read about all the withdrawal stuff and how wonderful people thought the drug was for their depression. But really, it was a wussy drug because it had no effect on my emotion/mood whatsoever. Is this a joke? I didn't even have a withdrawal. M 20 3 weeks
65mg 1X D
 5  depression ptsd weight gain but being emotionally healthy is more important F 6 years

 5  Manic Depression Sweaty hands & feet Euphoria This medicine has saved my social life. It has saved me from making terrible mistakes at work and around my family. My manic depression has driven to do things any normal person would never even think of doing and it seems as though I cannot live without the medicine. I think I may have to have my dosage up'd to the next level because the bad dreams and sudden outbursts are coming back I've noticed. Thank you Venlafaxine. You've saved my life and my daughters. I wouldn't recommend it to just anyone though. I'd like to think of it as a "last resort" type. I've tried countless other meds. But this is the only one that does the trick. F 27 2 years
75MG 1X D
 5  manic depression, Bi-polar, anxity Nausea, Insomnia, Loss of appetite, Dizziness, Dry mouth, Increased sweating, Constipation, Abnormal dreams, Weight loss, High blood pressure, Flushing, Abdominal pain, Twitching, Inability to sit still, A rapid heart rate, Fever, sweating, or shivering, Coughing, Extreme confusion, High cholesterol, Hemorrhoids, Liver problems, A decreased sex drive, My Dr. tried every medication and nothing worked, until he put me on Effexor XR. I started out on Effexor XR 75 mg, and was slowly raised from there to Effexor XR 300 mg. Then I was changed to the generic Venlafaxine XR 300 mg. I have had a lot of side effects with both of the medications, but it has been a life savor for me. I have been committed 3 times in the last 2 years. I was also getting 1 on 1 counselling but at the time I didn't have any insurance and the laws changed. So I had to start doing group therapy, and that didn't work. I always wanted to help others instead of helping myself. The Effexor XR worked wonderfully for me until about 2 1/2 years ago. I fell 4 1/2 years ago and broke my right ankle in 3 places and I ended up with RSD. Since then I have been in a power chair and I can do almost nothing by myself. I also ended up getting a blood clot in my right leg and was put in the hospital for that also. The Effexor XR worked so good for me with little or no side effects, until I was raised up to 300 mg. I feel that a lot of the side effects that I have are from the RSD not the Effexor XR.. I am trying to get back into counselling now. The counselling does wonders for me. As far as the liver problems, the Dr. told me I had a fatty liver. I am also on morphine for pain from the RSD. I would recommend for anyone to take the Effexor XR. The help that it has done for me along with counselling out weighs the side effects by far. F 49 8 years
300 MG 1X D
 3  Depression and Anxiety Effexor has undoubtedly saved me from countless spells of depression and anxiety, but knowing now what the side effects are, I'm not sure I'd make the same decision to get on it. I'm on a high dose, so night sweats (sometimes soaking the sheets) are an issue, as well as the crazy dreams and I think, some slight memory loss. The worst is the withdrawal effects. Coming off this drug is almost torturous for people. I know when I miss a dose it sends me into a tailspin. I'm not looking forward to the day I have together off of it. I took it while pregnant and I also believe it led to some issues at birth with my son's health (low muscle tone, feeding issues, withdrawals for him). The drug works well, but I'm not sure it's worth all the other symptoms. F 32 10 years
375 mg
 4  depression Sweating, sleeplessness and some dizziness (infrequent) 57 3 months

 1  Anxiety feel like a zombie. Headaches, fuzziness, drowsiness, and lightheadedness. B.P. went way up. I have tapered down to 37.5 mg. but have been unable to stop the medication due to terrible withdrawal side effects like insomnia, anxiety and panic attacks. Headaches and dizziness as well. F 52 4 years
150 mg 1X D
 1  Perimenopause I had a very severe and sudden reaction within 20 minutes of swallowing the pill. Vomiting, diarrhea, sweating, shaking, passing out, writhing on the bathroom floor for an hour. This was followed by a severe headache that lasted several days. Stay away from this pill!! My dr. told me that this was a mild drug with little side effects and put me on a low dosage. Nope - this drug was like a poison to my body. I would never recommend that anyone take it for any reason. I can't ever recall being that intensely sick - I lost 4.5 pounds in 1 day, and I'm already a skinny gal. Avoid this drug. F 39 1 days
37.5mg 1X D

 1  anxiety insomnia fibromyalgia Made insomnia and anxiety worse. I was never hungry, but when I did it, I was like a bottomless pit. I got bad headaches. Then I spoke with a friends parent who is a doctor and was told about the meth-like substances in effexor and how it should not have been prescribed for me for insomnia or my social phobia. Coming off of it has been easy for me, besides the constant moodswings, the fatique, headaches, and the nausea. I don't recommend anyone take this. F 19 2 years
37.5 mg

 1  depression and anxiety Omg, I kept feeling worse and worse and so stopped it. And then all hell broke loose. I had to go to the hospital for an I.V. I vomited so much--so much pain. That stopped but now I can't stop weeping, can't tolerate light or noise; can't read or watch tv, I'm a writer who can't write. F 69 4 weeks
75 1X D

1X D
 3  GAD / Mild Depression Day One - spacey, Day Two - nauseous, tight neck and head muscles, internal hot flushing accompanied by weakness and trembling, Day Three - nauseous, increased heart rate, warmer than usual, increased anxiety, Day Four - nauseous, digestive upsets, tight neck and jaw, prickling & tingling on skin, flushing, increased anxiety, experiencing zaps when falling asleep, woke in the middle of the night very hot, anxious, prickly, got scared, didn't take the med on Day 5, now decided I will try to tough it out, Day 6 - took it an hour ago, so far just tight neck and head muscles Too early to tell. I've read enough posts that I think I need to just get through the hell of the first two weeks and then move up to 75 mg and see what happens. Very anxious (duh!) about the whole process. F 51 5 days
37.5 1X D
 4  Major Depression Terrible night sweats (most nights), non-existent libido, concentration difficulties, unbearable discontinuation syndrome if I miss a tablet There's no doubt that Effexor XR saved my life, however long-term use is not the best. My moods are stable, but I'm now mildly and continuously depressed because of the two main side effects - lack of libido and bad night sweats. It's ruining my relationship, and so I'd really like to get off it but am terrified due to the side effects, and not knowing what I'll be like when I'm off it. I didn't have a choice but to resort to this drug, and I owe my life to it. It has made my life bearable, but introduced new problems which I never had before. F 23 9 years
150 mg 1X D
 4  depression I have not suffered any side effects. Effexor XR has been very helpful to alleviate my depression. Lately, I have had brief bouts of mild depression, so my doctor added Welbutrin XL 300 mg. F 58 6 years
150 mg 2X D
 4  Bipoar Depression Appetite suppression, insomnia, increased blood pressure, mild to moderate stimulant-like effects Effexor has been doing a pretty good job of combatting my resistant depression, in combination with an SSRI. The insomnia, increased blood pressure and stimulant-like effects of this medicine are mostly when I first went on it and for a couple of weeks following dose increases. I was up to 300 mg for several weeks but found myself getting irritable and moody on that higher dose. Overall I am satisfied with this medication, although I wish it didn't raise my blood pressure etc. F 23 4 months
150 MG 1X D
 5  OCD & Anxiety I started taking Effexor for my intrustive thoughts (OCD) and generalized anxiety. After trying multiple medications this one seems to be the best so far!! Getting adjusted to the med wasn't easy, but my patience has paid off. It has helped significantly with my anxiety and intrusive obsessive thoughts. Obviously I still get bothered by them a couple times a day, but that's much better then every 4 or 5 mins. Unlike others I'm actually losing weight, which is great considering Celexa made me gain 20 lbs in just two months. I feel clear headed which hasnt happened with any of the SSRIs I've tried. Although when I first started this drug I often felt high or out of it. I was worried about sexual side effects, but it hasn't been that bad. I'm just not as horny as I was before, which isn't a bad thing. Don't let bad reviews keep you from trying SSRIs or SNRIs each person reacts differently and it usually takes a couple med changes to find the right one for you. It's truly saved my life, and made it comparable to life prior to my OCD onset. M 24 3 months

 3  Panic Disorder, GAD Tinnitus, extreme constipation, apathy, fatigue, insomnia, weight gain, hair loss. I had to go up to 150mg to get rid of my daily panic attacks. The following are side effects I experienced from withdrawal: flu-like symptoms, crying, fatigue, brain zaps that would whoosh through my head and make my eyes roll back into their sockets, nausea. The drug worked, but the side effects both during and when I was weaning off are not worth it. There are other options out there. F 40 9 months
150 1X D

 2  Depression Excessive sweating. No sex drive. Dissociation. The withdrawal symptoms are the worst! F 21 3 years
75 mg 1X D

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