Drug Ratings for EFFEXOR XR

Average Rating: 3.1 (2056 Ratings)

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RATING  REASONSIDE EFFECTS FOR EFFEXOR XRCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
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 1  Anxiety disorder I was given this drug only once and it sent me into seizures which lasted all day. I had to be rushed to the hospital and it was serious. For a week I couldn't walk and could barely talk or lift my hands to take care of my kids. I threw my guts up and sweated profusely. It was a horrific experience and has scared me away from ever taking ANY anti-depressant again. I feel as though it left permanent damage to my memory and brain function. This drug was given to me right after taking Paxil. Don't know if that had something to do with the seizures. F 41
1X D
5/28/2011
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 4  Anxiety GAD Insomnia, delayed ejaculation but not completely gone, jaw tightness / ache, amphetemine like effects, loads of energy, crying, euphoria when combined with the gym, weight loss. So far I've found it to be generally good. Got some immediate relief and felt safe and secure with it. Full effects took 2 months though. The insomnia was a pain for the first 3 weeks but it wasn't until 2months that things began to settle down. Sex problems? Well for a guy it's not too bad. You get there in the end. Possibly the biggest problem was feeling up all the time. After about 30mins I was chatting rapidly like I used to do on speed or ecstasy. This was ok but at night I found it hard to sleep at least for the first month. Today I found myself very tearful over something trivial and feel quite down and depressed which I assume shouldn't happen on an AD. DO NOT TAKE WITH cold remedies / decongestion / cough medicines saying non-drowsy / caffeine / M 41 2 months
75 1X D
5/27/2011
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 3  hot flashes The sexual side effect of no orgasm was the worst and is why I stopped taking it. I had thought if this drug stopped my hot flashes and helped me sleep better, that my libido would improve. It didnít work out that way for me. The first three days on it I had killer headaches but continued to take it and they never re-occurred. I had to change to taking it in the morning instead of the evening or it would keep me awake all night. It gave me several tremors (more like full on limb jerking) everyday. Both the sexual side effects and the tremors occurred less often after a month of being off Effexor and they stopped being a side effect over the next few weeks . I didnít originally take this for depression but did get the benefit of it working for me in that respect. I was calmer, less easily agitated over the small things and just overall in a better frame of mind by the third week of taking it. I was surprised at just how good I felt! When I went off of Effexor F 56 90 days
75 1X D
5/17/2011
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 3  short temper, feeling overwhelmed I have experienced the "brain zaps" that some others have described. I usually take in the a.m. but just realized that drowsiness is a side effect! If I miss my morning dose, by lunch or so I am hearing (and feeling) these almost electrical type pulses in my head that get louder (I also have tinnitus) so it sounds like it's echoing off of my brain. If I don't have one with me that I can take I will go in to a full blown meltdown. Crying over nothing, feeling worthless (almost suicidal) headache, nausea, the whole nine yards. I have only been that way ONCE and I really felt like I wanted someone to shoot like like a hurt animal and put me out of my misery! I am NOT MAKING THIS UP! It works when taken properly, however, my goal is to get off of this med. I will be seeing my Dr for annual exam so I will hopefully be able to wean off and get on something a little less mind-altering! F 42 3 years
150 MG 1X D
5/10/2011
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 5  depression and anxiety inability to reach orgasm, but only for a short time when first startted and when upped dosage, weird "brain zaps" others mention and vivid dreams when miss a dose, inability to get off it due to withdrawl symptoms -- physical and emotional, but I was only trying to get off to start another antidepressant, so didn't really have to get off it I have been on an antidepressant for 18 years, most have worked (except for welbutrin) and I switched around to avoid side effects from some and to try to get better relief of anxiety. None have helped my anxiety. Effexor has worked for my depression very well, would not be alive without it. F 47 6 years
225 mg 1X D
5/3/2011
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 1  Depression, Anxiety Total nightmare. This was arguably the worst period of time in my life. It made me so mentally ill I almost ended up in a psych ward. Stay away from this if you can!! I lost weight considerably and shook all the time. I had terrible anxiety the whole time, the worst kind of anxiety I've ever experienced. Also tardive diskenesia was becoming very prevalent. Tobacco cravings were rampant. I never felt at ease or comfortable, I was constantly on edge and wanted to cry. Please be careful if you are taking this. F 30 6 months
30 mg 2X D
4/28/2011
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 1  Anxiety and OCD Increased irritability, overreacting to everything (couldn't control it), insomnia, excessive crying, headache. My doctor took me off after only two days because it was so bad for me. I would not suggest it, but remember that everyone has different reactions to drugs. I was also just diagnosed as bipolar which could explain my extremely bad reaction. F 20 2 days
37.5mg 1X D
4/25/2011

 5  Anxiety, PTSD, Depression None whatsoever! F 23 1 years
300mg 1X D
4/21/2011
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 5  Depression "Brain zaps" if dose was missed or late Taken for severe depression for 5 years and it helped me immensely. The only downside to it was if I missed a dose, I would feel "zaps" in my head which would make me feel very faint and a bit nauseous.These will go away if you TAPER OFF the medicine when you decide to come off it. I have been Effexor-free for a year now and do not have zaps any more. I am glad that it helped me. Like all antidepressants, it has side effects, but in the instance of severe depression this is one of the better drugs to take. F 31 5 years
15 1X D
4/16/2011

 5  Major Depression Side effects only when I miss a dose-dizziness, brain zaps I was on 225 mg for 11 years, then 150 for 1 year and now back to 225, due to Post Partum. Effexor saved me. I would have killed myself long ago without finding this drug. F 34 12 years
150-225 mg 1X D
4/11/2011
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 4  Axiety/Panic attacks Low sew drive. Very difficult to reach orgasm. Aside from sexual side effects, I only have problems if I happen to forget to take a dose. Effexor has done wonders for helping my anxiety issues. I used to panic about every little thing, now I no longer feel miserable with nervousness and fear that something is always going to go wrong. I do wish I tried some other meds first though. Last week I missed a dose by accident and it was one of the worst experiences of my life. At first I thought It was the stomach flu, but then came the famous "Brain Shivers". It felt like someone was shaking my brain around with my skull remaining still; then it would be followed by a brief moment of vertigo. I also had horrible nightmares, chills, and sweats. The brain shivers became more frequent until I took my next dose. After that, they became more intermittent until they finally stopped. It is horrible just how physically addictive this drug is. When my husband and I have conceive, The first thing I am going to do is try to get off of it so that my newborn will not have to go through Effexor withdrawal. It is SO AWFUL! I advise taking this drug as a last resort. F 29 2.5 years
75mg 1X D
4/5/2011

 5  Major Depression When I first started my depression was so bad i was suicidal, after 4 months of sucking it up and dealing with it Effexor saved my life and I say it confidently. F 21 24 months
150 1X D
3/31/2011

 4  Depression Night sweats regularly. If I miss a dose I go through the worst withdrawal. Heart palpitations, vivid nightmares, worse night sweats, and sometimes feels like my eyes do a weird shaky thing. Although the withdrawal really sucks. It's a great drug for me. I was baker acted 2x's before I started this medication for suicidal attempt/thoughts. I've now been clear headed and happy for 2 yrs. I'm just worried for when I want to get pregnant how that will go. F 27 2 years
225mg 1X D
3/30/2011
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 5  GAD/SAD/dysthmia Dry mouth, this went away with time. If I miss two doses in a row and take it, I feel drugged and sluggish for a day. No obvious side effects when I stay on schedule. I've tried a lot of anti-depressants and most had minimal to no effects. Effexor has changed my life. My anxiety is manageable, my mood swings are now within the normal range and the constant, underlying depression is gone. I've been able to go back to school and get a BA, something that was not possible before Effexor. Effexor isn't for everyone, but it's done wonders for me. F 30 2 years
150mg 1X D
3/29/2011
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 4  major depressive disorder I am not aware of any side effects. Not sexual, either. I'm fine. Effexor is the right drug for polio survivors. None of the others helped me. The scarring on my brain stem causes such a myriad of problems, and Effexor seems to be the key to making my brain chemistry work as well as it possibly can. I love it. I will take it forever. F 61 5 days
100 mg 3X D
3/29/2011
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 5  Severe Depression Severe Anxiety Di Flushing, weird thinking, anxiety Started at the standard 37.5, moved up to 75 and stayed on that for 4 years with great results !!!! Last year went up to 150 and recently ( this week ) started 300. My only concern is continuing to go up. But I will NOT give it up. I have a lot of work ahead of me, and realize there is no " magic pill " , but this saved, and continues to save my life. Now I just need to quit relying on it TOTALLY and work on myself too. Good luck to all out there !!! ( went for a 6 month period when they switched my from effexor to cymbalta and had NO side affects. I realize both are in the same drug class, and had NO clue so many people were going through these withdrawals. Much needed info for me. Thanks !!! ) F 48 6 years
300 1X D
3/26/2011

 3  anxiety disorder Tiredness al the time, just quit working Terrible withdrawal symptoms F 53 5 years
150 mg 1X D
3/26/2011
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 1  Panic Disorder, Depression, Anxiety agitation, insomnia, increased anxiety/panic attacks, feeling as if I wanted to crawl out of my own skin, loss of libido Terrible drug. I feel sorry for others who have endured the withdrawal symptoms after taking it long term. I quit after 6 weeks because I couldn't take the constant agitation/anxiety/restlessness it caused. I had hoped those side-effects would abate with time but they did not. F 27 6 weeks
75 mg 1X D
3/24/2011
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 5  Severe suicidal depressive episodes In the first month: dry mouth In the first year: slight tremors in extremities, no libido/orgasm Complete 9 years: eye sensitiviy to light, moderate weight gain but controlled with exercise and diet This drug saved my life. I would have run away from everything that mattered in my life and done myself in without the stabilizing effect of Effexor. I was willing to put up with the side effects because I finally felt like 'myself' again. The lows aren't as low and the length of the downs aren't as long - and so i no longer fall into a depressive cycle - I can deal with it. I would stay on this drug for the rest of my life if it wasn't for worries about my liver and just the accumulative effects after so many years. No I am noticing that my memory is terrible, as is my concentration. I am starting to do weird tihngs like put my running shoes in the fridge, that kind of stuff. I have read that long term effects can be on your memory - anyone else experienced this? I would be willing to gradually taper but also wondering if the underlying causes of my initial depression are still present in my body - so then what would be the point? I tried tapering off last year - got within 2 weeks of complete withdrawal and the first symptom that came back was crying jags and within a week I was into a full blown all out depression. I went right back on the drug and felt better within a few weeks, but I still dont know if my feelings were a result of not having the drug in my system or actual depression. Does anyone have any comments on their trying to withdraw after being on it for this amount of time? F 40 9 years
150 and up 1X D
3/22/2011
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 4  GAD/PD/SAD Dry mouth, with added plus of metallic taste all the time. Sexual side effects. Insomnia, slight tremors, body zaps when loud noises come out of nowhere. Lethargic once in a while. Effexor XR has helped wonderfully with my anxiety and panic attacks. I haven't had an attack in over a year. Before Effexor XR I was on Lexapro which left me feeling numb and I still had breakthrough panic. As with any SSRI/SNRI there are always going to be side effects but with Effexor I find there is way more good than bad. I have energy and I don't obsess over every little thing now (my husband's happy about that!). And I can go to a movie or a mall and not feel like I'm going to run screaming from the room. A good drug for me. F 40 1 years
225 1X D
3/17/2011

 1  hot flashes F 48 4 years
75mg 1X D
3/11/2011
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History
 2  Moderate depression and Anxiety Nausea, headaches, and dry-mouth. Affected my vision, I was "seeing frames". Reduced sexual sensitivity and trouble reaching orgasm. Lot's of energy but foggy head. Couldn't sleep. Made me feel a little high. Took it for three days then stopped because of the side affects. I have tried several other SSRI's and Wellbutrin. Never had a medication affect me that strongly in such a short period of time. The night after I stopped taking it I had very intense dreams, woke up in a cold sweat and had a terrible headache and upset stomach- Like a bad hangover, but I hadn't had a drop of alcohol-. Be careful it is a powerful one. M 28 3 days
37.5 MG 1X D
3/10/2011
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 1  depression I tried to kill myself witch mad no sense since I LOVE MY LIFE! The effexor worked great at first and then slowly i started to sleep more and feel more and more depressed, I also started having weird behavior. I never tried to hurt myself before this drug. F 23 3 weeks
37.5mg 1X D
3/9/2011

 1  Depression Nausea, vomiting, flu like symptoms, panic attacks. Felt "poisoned." Tried all the antidepressants, thought I would give this one a shot. Increased anxiety like mad! After trying 25 antidepressants, my doctor put me on 5 mcg's of Cytomel. After 15 years of depression, it went away in one day with Cytomel. It was like someone turned on the life switch. My thyroid tests were and are still normal.'I don't think big pharma has depression quite figured out yet. Try Cytomel!!! Read the testimonials on here, they are the same as mine. Start low and go slow (5 mcg's - 10 mcg's). No more than 10 mcg's per day.'You will feel like a dead plant come back to life! No generics! M 40 6 weeks
37.5 1X D
3/6/2011

 4  Panic slight weight gain, increased appetite, brain zaps when dose was missed. loss of sex drive 3 years free of panic...then it wore off. have been on lexapro, paxil, zoloft, cymbalta. this worked best for me. going to look into pristiq. F 31 3 days
37.5 mg 1X D
3/1/2011

 5  severe depression, anxiety, panic Insomnia, nightmares if i miss a dose This has been a miracle drug for me. I had cancer and couldnt quit thinking about dieing and my daughter being without a mother and my head felt just full of thought 24/7. I couldnt enjoy life for thinking about all the bad stuff that could happen. I was severly depressed, almost talked myself into leaving my family cause i didnt want them to get hurt if i died. I had every day anxiety, and panic attacks. I cried all the time, and wasnt the wife and mother that i wanted to be until i started this medication. It has cleared my mind, i can think positive for the first time in my life. I am a great mother, and my husband has seen a huge differance. I am so much happier, I plan to NEVER get off this med. I love it. It will be taken everyday with my bloodpressure pills for the rest of my life. It is a Godsend. F 26 3 months
75 1X D
2/24/2011
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 4  Anxiety, depression decreased appetite, increased sex drive, night sweats, some irritability if a day was skipped Over all like this one. Was on paxil - didn't work. Then Celexa - that worked but after 2 years - didn't help anymore. F 40 4 years
75 1X D
2/23/2011

 1  Depression/Anxiety/ADD Elevated AST and ALT Liver Enzymes; Lethargy; Apathy; Cognitve Impairment; Inability to focus; Tremendous difficulty for orgasm; You better get a script for Cialis, too. If you have HepC, BE REAL CAREFUL. As I weaned myself off of Effexor, my AST and ALT declined from 10 to 15 times normal level to very close to normal levels. I weaned myself from 225mg down to 15 mg. I started this in December 2009, and did it very very slowly. At the very most, the reduction was 12 mg every two weeks. At times I ceased the plan--but not because I was having adverse effects. DO NOT TAKE THIS DRUG UNLESS IT IS THE ONLY A/D LEFT TO TRY. IT WILL TURN YOUR MIND INSIDE OUT AND SPIT YOU ON THE GROUND. M 50 4.5 years
1X D
2/23/2011

 1  dysthymia; Borderline Personality Weight doubled from 150 to 300 lbs. Freakish sweating. I was NEVER suicidal or self-harming until I took this drug. I was sober when I began taking this drug; I began drinking. Then they diagnosed me with Bipolar Disorder I mixed episode. Then also on Wellbutrin 225 mg and Abilify 30 mg. I AM NOT BIPOLAR. Currently off all meds except 37.5 mg Effexor XR and soon will go off of that. WITHDRAWAL HAS BEEN HELL. Effexor XR is a stimulant. So is Wellbutrin and also Abilify. If I really had Bipolar Disorder, why would the docs prescribe 3 stimulants. I am mad about this. I had to go on disability. I lost 14 years of product adult working and living. Read "Prozac Backlash" It was written in the early 90's by a Harvard Medical Doctor. I wish I had read it before I took those meds. F 48 14 years
300 mg 1X D
2/20/2011
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 1  depression It is my son who is on this drug. I think it causes his daily nausea, his vomiting, his sweating. He was a nice even-tempered thoughtful caring young college junior who got depressed. Now after 7 years on effexor he is the exact opposite--he is irritable, short-tempered, has free-floating anger and rage at everyone, even at animals. Nothing ever suits him and he blames everyone and thinks they pick on him. He can't sleep well or at the right time or he over-sleeps. He can't keep a job because he feels so ill. He is now using more alcohol, I think to try to feel better from the drug effects. He does not figure it out that the drug has made him this way, because he is so addicted to it. Now his doctor says he is bi-polar. I am sure it was the drug that made him bi-polar. It has such terrible side-effects. As a child and teenager up to age 20 he was never like this. I am convinced the effexor makes him this way. I am so sad for him and all the other people harmed. This drug should be banned by the FDA. It does 100 times more harm than good and is causing serious disability in our young people. M 27 7 years
150 1X D
2/19/2011

 4  Depression Vivid and exhuasting dreams, require more sleep than usual, STRANGE INTENSE dreams, Other than that no bad side effects. I have more of a sex drive now (could be because depression lifted) This drug has helped a lot with my depression! F 23 3 months
75 1X D
2/15/2011

 5  serious depression + anxiety some constipation and very brief period of occasional night terrors for about first 6 weeks, but since then, none Initially tried Celexa, which only caused symptoms to worsen. Then tried Effexor at 150 mg/day, which helped almost immediately. Dr. later increased dose to 300 mg/day which, along with cognitive behavior therapy, helped me get back to healthy mental state within about 3 months from start of my symptoms and I have been doing well ever since. I have thought about trying dose reduction, but really don't want to risk withdrawal symptoms. Taking this drug is really no different than taking my daily cholesterol and blood pressure meds that I'll be taking for the rest of my life. Patients should realize that: 1) each person reacts differently to each anti-depressant, so unfortunately finding the right drug is a trial & error process and 2) drugs ALONE are not the answer to mental health issues - you have to be willing to work with a therapist to change your negative thoughts. M 62 10 years
300 1X D
2/6/2011

 5  "Depression", PDD, PTSD. After a lifetime of distress, I now feel more like a normal human being. F 61 3 years
150mg, 1X D
1/31/2011

 5  cfs dry mouth, night sweats, nervousness I heard about this med after listening to a talk on CFS. I tried it and it has helped so much. I dont know where I would be without it. It clears the 'brain fog' completely, and gives me the strength to deal with everything in a positive light. I have tried to ween myself off this med (for 6 months) but I found that the benefits outweigh all else. At the end of the day---its about quality of life ! M 50 13 years
150 1X D
1/23/2011

 4  Depression At 37.5mg my depression is controlled. I will experience episodes of depression but it's manageable. When I increase the dose to 75mg I experience vivid dreams, interrupted sleep, anxiety, irritability and unwarranted anger. For me, this medication manages my depression if I take it at a low dose. I have not gained/lost weight, but I am an endurance athlete. F 47 6 years
37.5 1X D
1/22/2011

 1  PTSD Horrible, visual interuptions, feeling like i was having electric shocks in my head which lasted a year after getting off, horrific nightmares,suicidial fantasys (i'd never been suicidal before!) night sweats-PJ's soaked through!, angry/violent outburst, took 3 years to get off it, terrible terrible withdrawals I lost my job & 4 years of my life to this drug it should be illegal and I'd like compensation!!!! I still suffer from the nightmares although not as vivid, I think this drug does irriversable damage! F 37 4 years
300mg 1X D
1/14/2011

 2  bipolar ii + depression/anxiety intense increase in anxiety and agitation seems that effexor caused an episode of hypomania with extreme anxiety resulting in increased depression; not a good mix for my condition; regime includes lithium (1500mg); lamictal (300mg); buspar (50mg); abilify (15mg) M 40 90 days
1X D
1/12/2011
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 1  depression/mood disorder WORST WITHDRAWAL EVER. I've been on anti-depressants for at least 5years, and I've tried multiple ones but by far effexor was the worst. Yea it helped during the time I took it. But if I missed a dose I got those "brain zaps", and I just felt in a fog not myself at all. But when I came off it was the WORST experience I felt like I was in withdrawal from a hardcore drug. Brain zaps constantly, the shakes, sweating, nightmares, anxiety, muscle spasms, and crying spells. Don't take effexor its not worth the risk of a horrible withdrawal. It has a half life of 5hours, that's why you feel so crummy after missing one dose. awful awful medication. F 18 1 years
350 1X D
1/9/2011

 5  Major Depressive Episodes, Anxiety If I miss a dose by even a few hours I get horrible lucid dreams. The worst of my life. And withdrawal effects sink in within hours. If I remember to take it at the same time everyday there are no side effects. It's a miracle drug. This has given me my life back. After Prozac, Wellbutrin, Zoloft, Celexa, Paxil, and a few others failed to help me Effexor finally did the trick. I had to be patient though. It took between 2-3 months for me to really feel close to "normal" again. It did not help me until I worked up to the full dose of 225 mg. So please be patient and give it a chance to work its magic. I have interest in things again, I don't sit in a corner and cry for no reason, and some of my social skills are coming back. I can actually enjoy some company. I don't have the urge to die anymore. I feel moderately content with my life right now which isn't great, but is a HUGE step up from the dark hole I was in. F 24 6 months
225 MG 1X D
1/3/2011

 4  Depression/PTSD/Panic attacks Horrible Nausea at first and when dosage was changed, tired, difficulty sleeping, libido is actually better than before. I was in a really bad place. Nightmares every night and tired all day, almost to a state of paranoia. Tried other drugs but the effexor xr seems to be doing the trick. It is a slow process and I take mirtzaphine at night. But I also keep all my therapy sessions. The drugs can not do it alone. I have resolved myself that I will probably be on the this or something else the rest of my life. F 51 18 months
150 1X D
12/29/2010

 1  Depression, anxiety Lowered libido, dizziness, nausea, feeling as though I was outside of myself, strange appetite, headaches, restlessness (couldn't stop tapping my feet), possible vision changes? (severe difficulty driving at night), frequent yawning, bizarre dreams and nightmares, tiredness, difficulty concentrating Effexor made me feel as though I was constantly drugged, as though I was outside of myself and looking in or in some twilight zone (very difficult to describe). I went off the medication cold turkey, and the withdrawal was brutal - I missed four days of school because I couldn't stand up for more than a few minutes at a time without feeling an intense dizziness, almost as though my brain was sloshing around in my head. I suffered from paranoia in which I thought people were going to come through the window and shoot me. I was able to finally make it to school on a combination of Dramamine, Motrin, and Xanax. I would not wish the withdrawal on anyone. F 17 1 months
37.5 1X D
12/22/2010

 3  Depression, GAD, Panic attacks Fuzzy head, dizzy, nausea, fatigue, irritability, anxiety, difficulty concentrating, anhedonia, addiction, headaches The drug seems to work somewhat for depression and anxiety but has left me feeling angry, anxious, lack of feeling, wired and fatigued while on the drug and depressed, anxious, nauseous, with trying to go off the drug. Was on Pristiq 50 mg for a while tried to get off and could not withdrawal without craving for the drug, so asked to go on low dose effexor xr to satisfy my craving. This drug is addictive and has bad withdrawal. It can work for some people, just don't believe that it is any safer than other addictive drugs, remember all newer drugs are not addictive like cigarettes weren't a long time ago. All psych drugs can form a dependence, best not to start on drugs if you can manage another way. M 43 2 weeks
37.5 1X D
12/21/2010

 2  Depression/Anxiety Sexual appetite depleted, mood swings, nausea, and slept all day. Helped w/ depression but not my anxiety too much. After getting off XR--6 years later I am still experiencing some of the side effects. Mainly night terrors, hallucination, and dizzy spells after I awake from a night terror or bad dream. I can't recommend this drug. M 31 2 years
75mg 2X D
12/14/2010

 4  Depression/ Anxiety Weight loss. Dilated pupils. Tired all the time! - Sleep a lot. Probably sleep away half my life :( Helped with my random deep depressions that I would previously have, but seemed to cause a more prolonged mild depression. Don't think it helped with anxiety at all, in fact it may have caused me to have more social anxiety. Took me many years to realize this but I have great difficulty concentrating & loss of motivation ever since being on this drug. I used to be a lot more physically active, I used to always turn my homework in on time and be on time to things. Straight A student. Now I am the opposite, I sleep all the time, have no energy to work out, I procrastinate, struggle focusing on my reading for class. Also - when I first started taking this medication I noticed I had difficulty having an orgasm for the first few months, but this went away later on. It may be more difficult for me to have one, but I am now able to. F 25 6 years
150mg 1X D
12/13/2010

 2  migraines, anxiety and depression Mainly, insomnia, and migraine headaches got worse! Initially, it really helped with my depression but as time went on, had trouble staying asleep--averaged 5-6 hrs./night and I need at least 8-9 hours of sleep! Also, as time went on, I would wake up in the morning (after 5-6 hrs. of sleep) with a migraine coming on and pain in the back of my head/neck like someone had hit me with a frying pan! I even tried cutting back (1/2 of 37.5 mg) but that did not work either. It took about 10-12 days after I quit taking it before I started feeling better with my head and sleeping 8-9 hours. F 60 6 weeks
37.5 mg 1X D
12/6/2010

 1  Depression and OCD I tried to overdose on 1375mg of this drug. F 16
1X D
12/5/2010

 4  counter acts tamoxifen for breast c none a little weight gain stoped hot flashes from tomoxifen an anti breast cancer drug F 50 6 months
75 1X D
11/29/2010

 4  Suicidal Depression/Anxiety At first I had some nausea, excellent wet dreams, insomnia, dilated pupils. I guess I can't complain. The drug has indeed lifted my depression when Lexapro started failing. I don't really enjoy my life though. I feel like I could do anything and it wouldn't really matter. The drug has a pretty big zombie effect on me more so than others I've taken. Maybe I'm on too high a dosage. But I have to say I like it since it pretty much saved me from committing suicide. It's just gonna be hard to reclaim my life and emotions. M 28 5 weeks
300mg 1X D
11/26/2010

 1   more depressed and aggitated. All I wanted to do was sleep and I had to have help taking care of my children because I was too tired to. =( 2nd worst med I've ever tried. Topamax was the worst. F 33 2 weeks
37.5 1X D
11/23/2010

 5  Major Depression/Anxiety Initially erectile dysfuncion, used Viagra, then didn't need it anymore. ED went away after a few months. Through the entire time I was on Effexor skipping a dose was a real problem-- disjointed thoughts, anger, truly strange dreams. I switched to Effexor XR after a couple of years on Paxil. Paxil saved my life from obsessive suicidal thoughts, but after a couple of years I started abusing my son's Ritalin (he has ADHD). My doctor switched me to Effexor XR. It worked beautifully. I was on for about 5 years and felt so good I titrated off it with help from Prozac. I've been off Effexor (and all anti-depressants) for almost a year with no negative effects. I feel like the Paxil, the Effexor and staying busy, focused and positive "changed my mind" from tending to depression, drug/alcohol abuse and anxiety to health. M 48 5 years
225 MG 1X D
11/22/2010

 4  PPD, GAD First week was a little rough. Felt jittery and nauseous. Occasional night sweats. SLEEPY, but had difficult time falling asleep at night. Increased appetite. Short term memory wasn't very good while on it. Effexor absolutely worked for me. I started to feel relief from my PPD in 1 week while on it. Then my anxiety went away, been dealing with that all my life. I felt great! At times even euphoric. I still felt emotion, I could laugh and cry when appropriate. No change in my libido(yay!). If it weren't for the side effects I would probably stay on it. The side effects are not cool. WEIGHT GAIN, hungry ALL the time! SLEEPY, but had a hard time getting to sleep at night. Short term memory loss, felt ditzy at times. It was mostly the weight gain that made me quit taking it. I worked out 5-6 days a week but could not control my cravings and continued to gain weight. I tapered VERY slowly. I opened the pills and would slowly increase the amount of the little balls that I would take out. I had ZERO withdrawal symptoms. I would recommend Effexor to others and would consider going on it again if I were going through a rough time (although as briefly as possible). F 33 1 years
75mg 1X D
11/19/2010
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 4  Anxiety Disorder First 2 weeks: Nausea, drowsiness, loss of appetite, weight loss, night sweats, heart palpitations. These actually go away after awhile. After a few months: brusing, increased risk of bleeding, decreased clotting time, bleeding gums, decreased sexual interest, breakthrough menstral bleeding. Was on 150mg at one point, but wasn't able to have emotions (never really happy & could not cry when appropriate) so dose reduced to 75mg. Do not skip doses, or stop taking "cold turkey" or will get withdrawal effects: feeling of electric shock or zapping through nerves, sweating, heart palpitaions, crying spells, difficulty sleeping. Works well for anxiety & preventing panic attacks... but takes a few week to get full benefits of medication Go up slowing on dose to reduce side effects and go back down in dose slowly when going off to prevent withdrawal. If your emotions are too flat (never happy or sad when appropriate) your dose is too high. Take with food to reduce nausea. I don't take anymore b/c I don't need right now, but would consider it during times of stress. F 29 6 years
75mg 1X D
11/15/2010

 1  anxiety slight depresstion social a After a few hours of taking effexr xr generic form became very disoreinted cconfused dizzy swimmy headed. Felt like I was not in my head very odd strange undesciable feeling. By next morning was having seizures had never had seizures prior to this. Could not walk on my own and it was a blessing that I was at home and not out in public alone somewhere. Single mother of 4 teenage kids scared my kids to death. I took effexor a few yrs back but didn't remember how it effected me untill my ex husband reminded me that it done the same thing last time. I don't recommend anyone try this medication, after only one dose I experienced what could have been life threating effects. I'm on day 2 of not taking it and am still loopy feeling. Seizures have slowed down. Extreme hot flashes then cold chills. My brain is still swimmy and my dr says that this can continue for an unkown amount of time even though I only took one dose.everybodys body reacts differently to this med and it stays in some peoples system longer than others. I am now being ordered by my dr to be under "watch" by family or friends untill this passes or go into the hospital. It scares me to think how bad this could have turned out if I had continued to take this medication one day longer. It may work for some but make sure you do your research before taking. More bad effects with this medicine than good. F 35 1 days
75mg 1X D
11/11/2010

 2  Major Depressive Disorder I have MDD and have had depression for over 20 years. I have also had severe anxiety and agoraphobia in the past. I have had Effexor a few years ago and remembered that I had a terrible time coming off it. But this time around because I've had one of my worst meltdowns ever my doctor has prescribed it again even though I expressed concerns about the effects of the eventual withdrawal. I have beern on it for four days so far this time around and I feel very strange, like the world around me is unfamiliar and strange and frightening. I got in the car to go to work this morning and ended up having a panick attack. I drive around the block a few times and in the end came back home and called in sick. I work in a high pressure where I need to constantly think outside the box and I'm worried that I'll start freaking out and failing. I also cannot reach orgasm on this med. I really hope I can overcome these feelings of strangeness and unfamiliarity of my suroundings and my fear of going back to work. This is my fifth day off sick and this drug is giving me a haunting fear of going back. F 36
75 1X D
11/7/2010
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 5  Depression, Anxiety At first, nausea and headaches similar to what I experienced with Zoloft and Celexa in the past. After a couple weeks, nothing. This drug made a huge difference for me. I gradually have worked up to 225 mg (37.5 mg for 6 days, 75 mg for about a month, 150 mg for a couple weeks, and now 225 mg the last three weeks). People complain a lot about withdrawal on this med, but a lot of them don't taper like they should. A lot of family practice docs don't have enough experience with antidepressants to know exactly how quickly to taper the dose. At first this was a concern for me too, but my psychiatrist assured me that by tapering correctly, most people avoid major withdrawal symptoms. I'm a second year medical student, so I think I a reasonable amount of knowledge to know that he isn't just trying to make me feel better for the time being. Anxiety ruled my life before Effexor, and my latest episode of depression was the worst of many. I was having almost constant GI problems, which have been attributed to my mental health struggles. I came closer than ever to killing myself. THANKS TO EFFEXOR I feel like I have my life back again. M 24 3 months
225 mg 1X D
11/3/2010

 2  Mild Anxiety Profuse sweating, which was unbearable at times. It is very hard to discontinue this drug, even if weaning slowly off. Nausea, head feels funny, bad overall feeling. I will not go on antidepressants again. F 50 3 months
37.5 - 75 1X D
10/28/2010

 2  anxiety panic attacks agoraphobia irritability, severe weight gain, insomnia, really bad withdrawal symptoms from missed doses I wanted to tell other people that I think there is a way to get off this drug. I'll tell you what I am doing that seems to lessen the withdrawal effect. First get a notepad because you are going to want to write everything down because you will be decreasing your dosages. Your effexor XR capsule will have little white beads inside of it. Depending on your dosage, that is how many beads are in it. My dose is 75 mg, so I have 75 little white beads in it. Step 2 is to get a small dark colored bowl and a pencil. Next wiggle "cap" off the capsule. This is the shorter end of the capsule. Once you have it off then set it to the side. Now you will see that there are the tiny little white beads inside. Do not dump the entire content of beads into the dark colored bowl! (I use the dark colored bowl since it's easier to spot and count the beads). Now while holding the capsule, tip it slightly to loosen the beads up and grab your pencil. With the pencil tip, easily scrape the beads out one at a time if you can. Always check your bowl and COUNT the white beads because you need to be exact. EVERY DAY YOU WILL REDUCE YOUR DOSAGE BY 5 WHITE BEADS! DON'T REDUCE BY ANYMORE THAN THAT OR YOU WILL DEFINITELY EXPERIENCE WITHDRAWAL SYMPTOMS! Once you remove 5 beads from the capsule, screw the top "cap" on snug. You will have to wiggle it back on. Discard the beads preferably in an old medicine bottle with a child-proof cap. Take the capsule with at least a bottle of water to wa F 31 10 years
75 mg 1X D
10/26/2010
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 5  Psychosis No side effects at all. Lifesaver drug. M 23 2 weeks
150mg 1X D
10/24/2010
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 3  depression, bullimia crazy dreams, sweating, weight loss I can trully say it worked when I was on it. Actually went out and had fun, looked good and felt ok. It was the getting off that is scary. Tried once and was hospitalized for dehydration. Second day with no pills vomiting, diareah, had dreams of dying, sweating buckets, dizzy as hell. Second time around I was prepaired, loaths of white bread and gatorade withsome ignatia for 4 days. Stayed in bed for 3 days sweating and dizzy...But got off it! F 27 2 years
150 1X D
10/20/2010
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 3  Anxiety, Depression Weight gain (12kgs), Constipation, Fatigue, Hair Loss (permanent), Bleeding (nose). Side effects became noticeable after 2 years and worsened after 4 years. Worked perfect on anxiety. Also noticed personality "change" (more outgoing, calm etc.). I quit after 4 years due to the side effects. After 10 months without any medication, anxiety and mild depression is back. M 37 4 years
150mg 1X D
10/20/2010

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