MIFEPREX Reviews (MIFEPRISTONE)

Average Rating: 3.6 (68 Ratings)

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 Type: Rx Drug

  

MIFEPREX  (MIFEPRISTONE):  This medication is used to control high blood sugar in people who have a certain condition (Cushing's syndrome), and who have failed surgery or cannot have surgery to correct the condition. Cushing's syndrome is caused by the body producing too much of a certain hormone (cortisol) which can cause glucose intolerance or type 2 diabetes. Mifepristone works by blocking the effects of cortisol.   FDA Approval Date: 2000-09-28 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on MIFEPREX: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR MIFEPREXCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5   The pain medication (vicodin) gave me an upset stomach and made me tired but that was it. I had no side effects with the mifeprex its self. The cramping was no worse than a normal period for me, probably because of the vicodin. The "women" on here that say it was horrible and very painful are trying to scare you away from abortion. It's hard to find real patient experiences on the internet, this was the only one I could find. After reading these comments I was hesitant, just as the person below me. I went to the clinic. The procedures were easy and painless. The worst part was having a vaginal sonogram because the doctor couldn't see the pregnancy with a regular sonogram and it was only slightly uncomfortable for a couple seconds. You take the cytotec vaginally 3 days after your visit to the clinic at home and it does require you to lay down and not get up for 8 hours. My cramping started about an hour after I took it and I started to bleed 4 or 5 hours later. The cramps are mild to slightly painful and the pain medication helps a lot. I suggest clearing out your schedule the day after and having someone to help you that you trust. I was terrified of a surgical abortion and decided to try this is an F 19 4 days
4/11/2008
 5  early pregnancy termination 5 weeks I had zero side effects from the mifeprex(the first pill taken orally) 24 hours later I dissolved the 4 other pills in my cheeks. Different clinics use different procedures. Some give you 4 pills(Cytotek) that you insert vaginally. I had to dissolved them in my cheeks for half an hour. That itself wasn't too pleasant, they tasted horrible. Before the pills were even entirely dissolved I began to feel cramping in my stomach. This cramping became severe within about 2 hours. I had a prescription of 4 tylenol with codeine pills. That was all for the pain. Even with the codeine the pain was excruciating. Enough to keep me moaning and I had bouts of crying that I endured. Maybe after about 5 hours I began to feel better. Then I just slept. It took a lot out of me, however it worked. I had morning sickness before taking the pills,,,within about a day or two after, I felt like a million bucks. Besides the bleeding, that did last for about two weeks. Started out with a lot of F 29 2 days
4/21/2008
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 5  unplanned pregnancy The side effects.. I went to the Dr's they did blood work, urine test and then ultrasound (all within 30 minutes) and found out I was exactly 6 wks 5 days pregnant. Dr. gave me the mifeprex pill to take orally which i did. Then handed me a small bag with the 4 misoprostol tablets and told me to insert vaginally within 72 hours. Side effects w/just the oral mifefprex were nausea and sluggishness but not enough to miss work or be in pain. I noticed a slight brownish discharge about a day after taking the oral pill but had no cramping until after inserting the 4 vaginal tablets I waited to insert the vaginal tab's because I went out of town so I waited almost 2 days after taking the oral mifeprex.The Dr. told me not to wait too long after because the abortion may not work...Woke up at 3am took Tylenlo 3 and waited... 4am, inserted the vaginal tablets and just went back to sleep, woke up at 8am and got up to use the bathroom and was already heavily bleeding with clotting. I did take the Tylenol 3 before inserting the tabs but the cramps were pretty strong..The really bad cramps lasted from about 8am to 1pm that day. Had to use a pad for the next 5 days because of heavy bleeding. I only took 3 more Tylenol 3 pills throughout the 5 days and mixed it up with ibuprofen and then midol. About day 4 I noticed some heavy cramps and pain in the abdomen but also discharged more clots with may have been the last of the embryo. It's now day 6 and I am almost done with the bleeding and cramps. I'm going in to get an IUD asap. F 37 6 days
7/25/2009
 5  6 weeks pregnant / medical abortion I took the first pill of mifeprex in planned parenthood ct on day one felt pretty nauseous. then four others at home in cheek n gum two each side abiut 34 hrs later.. I was prepared for the worst after reading so many frightening outcomes but after disolving the four pills at 1115pm I felt nauseated so I laid down around 11:40pm. fell aslp and woke up at 2 am my husband asked if I was ok I said yes nothing is happening I feel fine I figured it didn't work. so I went back to bed and woke again at 440 had to pee still no pain no cramping nothing. I did have a bloody pad on and after peeing I felt a gush of blood than a good size clot came out and then I had cramping and it was over. no side effects just slight nauseous. I was so worked up and terrified to take the remaining four pills I was crying and ill over the whole thing. I am a mother of four this was a big accident but I feel ok. not all that much bleeding either. just do it and you will have your own experience. everyone is diff but id say try not to work yourself up by reading everyone elses experience on here. you are promted to seek medical help right away if you have certain issues. you will be ok as most have. thank you F 32 1 days
12/28/2013
 5  6 weeks pregnant Took the first pill at the clinic , no side effects at all. Next day inserted the 4 other pills vaginally but about an hour before I did that I took 3 Tylenol 3. Which helped the pain a lot. After insertion about and hour later I started to bleed then about an hour 30 later the sac came out. The pain is about a 1 on a scale of 1-10. F 21 1 days
12/5/2013
 5  3 weeks pregnant I took 1 tab orally. Then 4 buccal 2 days later....... had light bleeding for about 10 hours..... medium cramps. But definitely tolerable. F 31 1 days
4/17/2014
 5  6-7 weeks pregnant For anyone taking Mifeprex, 800mg of Ibuprofen will not help you with these types of cramps. The cramps are very strong labor cramps. You need to take another strong type of medication with it and you will be fine. Be somewhere comfortable and make sure you are on a full tummy. People do not understand that Ibuprofen alone will do nothing for you. Put on a maxipad. Take some STRONG medicine. And sleep it all away! I had a good experience, I was knocked out the whole time and I did not go through any of those horrible stories I have read. I did have 1 huge clot when I woke up. It will not be as fast as the surgical, but it is much less invasive in my opinion. I took it a couple of days ago and now I am having what feels like a regular period. I have not gone to the follow up yet. All i want to say is Dont be scared, girls. And I wish all of you the best. This is what worked for me. F 19 1 days
4 pills 1X O
10/1/2014
 5  Abortion Cramps bleeding nausea I was only 3 weeks and 2 days pregnant but the ultrasound woman lied and told me I was 6 weeks and 6 days which I knew was impossible. They do this to get more money out of you. Took the first pill mifepristone at the clinic and felt nothing at all. Took mifeprex the next day at 4:30 held them in my cheeks for about 10 mins. Cramps started to set in about an hour and a half later so I took 2 ibuprofen. Another 30 mins and the cramps start to get worse and worse then the ibuprofen sets in and they subside to mild cramps. I laid in bed watching TV for about 3 hours waiting on the bleeding to start and eventually around 10:00 is when I started to bleed. I had small clots and mild bleeding due to not being that far long I'm guessing. I bled moderately all night and when I woke up the worst was over. After that my nausea was gone (thank god) and I spotted for about 2 weeks then got a very mild period a week after that. Overall my experience was easy and not bad at all. F 23 1 days
5/28/2015
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 5  Medical Abortion Nausea, cramps I went to the clinic Thursday morning. They did an ultrasound. I was 8 weeks and 1 day. They did my labs to make sure I wasn’t anemic. I had to watch a short video and counseling session to make sure it was really what I wanted. At 1:30pm I took my first pill at the clinic. I went about my day with no side effects. I ate dinner around 4pm Friday and started to have some bleeding. After I ate, I took the prescribed pain medicine and nausea medicine. I waited 30 minutes for it to kick in. At 6pm I took the 4 pills (2 in each cheek) and waited another 30 minutes. I swallowed the remainder of them and almost IMMEDIATELY I feel the pains and nausea. About 15 minutes later, I got sick and that was the end of my nausea. The cramps were bad but they were not unbearable! I took 2 Tylenol extra strengths and used my heating pad. The cramps came and went for a few hours. At 10:30pm I got sick again and the cramps were getting worse. I felt another big fish of blood. At 10:45 the biggest “clot” I had came out and I distinctly knew it was the sac. Immediately after the cramps, nausea, everything was completely gone. I got a good night sleep and got up the next morning feeling 100% back to normal. Since then I have had very light bleeding. I got back for another check up Friday to make sure everything worked. I worked myself up reading all the reviews. I was terrified to take the pills. Ultimately I am very pleased with the process. For someone that does not do pain very well F 22 2 days
11/12/2017
 5  Abortion Intense cramping. I did not have any side effects at alll. I am very glad I did it this way. I went to planned parenthood on Saturday and I took the first pill at the clinic and 24 hours later took the 4 cheek pills and let it dissolve 30 minutes. At exactly 30 minutes I started feeling the cramping and the sac came out. The heavy flow lasted 3 hours. After the heavy flow it was just like a light period. The cramping was very intense was not able to fall asleep but took 3 Tylenol and it knocked me right out. The following day I felt like myself and went to work. F 22 2 days
1X day
10/27/2020
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 5  Abortion 8 weeks Cramping, heavy bleeding, nausea and diarrhea The first pill wasn't bad,the four I took the next day is what did it...I was in so much pain but I toughed it out.Just glad it's all over with F 31 1 days
1X day
2/18/2021
 5  Abortion Everyone's leaving a review about their own personal experiences, please stop telling people what will happen or what they should do because everyone's body is different. I was literally terrified to go through this process because of all the horror reviews I read. But my experience was so mild I was scared it didn't even work. I took the first pill with the doctor at 3pm, came home and by the night time I had some light bleeding. No cramping. 24 hours later, I took ibuprofen 800 30 minutes before taking the second dose of pills (2 in each cheek) I let them dissolve 30 minutes and swallowed the rest. I laid down and awaited my demise lol but literally guys these cramps were lighter than regular period cramps. I did experience some nausea and threw up my dinner, but I had been nauseas from the pregnancy every day so idk which to blame. After about 30 minutes I passed the sac, a few hours later a few more small clots and one more medium sized one. The next day was just bleeding of a heavy period. No bad cramps or major discomfort. More so the emotional pain and concern. Again everyone's body is different. Don't be afraid from someone's horror story because yours may be smooth sailing. And don't get too amped up over someone's smooth sailing because yours might not be that way. Either way you will make it through! You got this girl F 29 1 days
200 1X day
10/7/2021
 4  Abortion Intense cramping, feeling very warm I've had to use this method twice because, as we know condoms are not the best, and I was told by the lady that I would have terrible pains. There was another lady the first time who said that I am basically going through labor, therefore, I would get the same pains as a woman in labor would get. They tried to give me Tylenol with codeine but I refused it, seeing as I couldn't pay for it. They told me it would be worse pain if I didn't. It was absolutely TERRIBLE. I had I take it at night and I got NO sleep. However, I will say the cramps went away with the help of ibuprofen and a heating pad and after a few hours they were normal cramps and then gone. Although, each person has a different pain tolerance, so not everyone will feel the exact pain I felt. F 20 1 days
6/1/2017
 4  Medical Abortion Brief Fever, Itching, and Redness Severe Cramps Severe Fatigue Dizziness Nausea Vomiting Headache Muscle weakness Severe Diarrhea I took Mifeprex (the first pill) at my local Planned Parenthood, was all good except for some really slight cramping. As instructed 24 hours later I took the Misoprostol tablets, holding 2 in each cheek for 30 min. They don't completely dissolve in that time, so I swallowed what was left. While I was waiting, maybe 10-15 min into it, I started to feel the familiar pain of regular period cramps, every minute after the pain got worse. At that point it was just moderately increasing cramps, and what felt like gas pain/ diarrhea. At maybe minute 28 I drag myself to the bathroom, which was hella harder than it should have been due to extreme fatigue. Basically, rode waves of seriously intense pain. They say that your supposed to have an experience similar to your worst period, I don't know whose period I was channeling because I have NEVER EVER had a period remotely equal to this. I felt my face get hot, so much so I had to lean my face against the wall. My skin was burning hot. My palms started to feel the same way, swollen, itchy, and hot. It was hard to breathe, my chest was tight. I was shaking like a leaf in a blender on high. Luckily, common sense berated me into walking. I could barely stand my legs shook so much. Mash Emergency Care was less than a block away, normal walking distance. Figured can't hurt. Severe shakes turned a 3 minute walk into 15 min. Any smell close enough made me sick. Not so elegantly I sprawled on to the reception desk, signed in, and wait F 24 2 days
5/23/2016
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 4  Abortion Pain in stomach, tiredness, muscle cramps F 27 2 days
1X day
7/13/2016
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 4  termination of a 4 week pregnancy From the mifeprex alone, I honestly didn't feel much different - just a growing dread of taking the misoprostol to complete the process. I admit I was terrified of having a bad experience like most of what I've read here, esp the one comparing it to the surgical procedure and how the pill isn't "worth it". I'm glad i tried out the pill option, really. It went like clockwork and the pain was completely manageable with my lortab prescription and anti-nausea pills. No diarrhea, never vomited, and my cramps were of moderate to heavy period strength. I sat on the toilet after I'd been bleeding lightly for an hour (this was 4 hours after taking misoprostol) and passed what I think was the gestational sac and placenta. Every few hours after this, I would drop clots that seemed large but not painful or suspicious and so on until I fell asleep for the night. That's it. My bleeding basically stopped the day after. Now, on that next day, I would try to keep in mind how traumatic in comparison to aspiration abortion, the pain here was NOTHING! my experience with the surgical procedure was not as easy as some like to describe, but then my recent trial with the medical abortion was a walk in the park compared to some womens' horror stories. i prepared myself for the worst mentally and physically, but was relieved with how easily the process took care of itself. i'm grateful to have had the comfort of my home and partner to guide me through the emotional part of it. the absolute worst moment in all this was seeing what my body passed into the toilet and the thought processes that followed. in that respect, i wish that the US handled medical abortion the same as in the UK - with women undergoing their "miscarriages" in a hospital setting and then sent home to recover. it seems a little more humane in terms of tissue disposal and monitoring of all the side effects that can occur just after taking the misoprostol. Don't be scared to try this because of the more intense and negative experiences you find researching online. Not to discredit what these women went through, but if you're in the category of those who have this pill option, don't put yourself through a surgical procedure if you can avoid that type of invasion and (very different kind of) pain. F 20 1 days
11/1/2009
 4  terminate early pregnancy Cramps, tired, out of commission for a day I missed my period and went to the doc the next day. Much less traumatic than I thought it would be. F 22
7/27/2009
 4  Medical Abortion After taking the first pill, I had no side affects. I was actually worried that I was feeling too good. I was afraid the medication wouldn't work. After dissolving the four pills in my cheeks two days later, I had no doubts it was working. I was surprised by the intense pain of the cramping. I think it was the worst pain I've experienced, although, needed. They started slow at first, and then intensified for about two hours until I passed the tissue. I was given vicodin, which I took before hand, but I don't think I gave it enough time to kick in. Also, eat before you take the second set of pills!! I was horribly sick, and vomiting nonstop because they had upset my stomach.But, it is more private than a surgical abortion, and they highly recommended it because I was only 4 weeks pregnant. Overall, I think it was a better alternative and I'm still happy with my decision. F 19 3 days
9/5/2009
 4  unwanted pregnancy This is the second medical abortion ive had and this one is the worst. Idk why everyone else had them melt in their mouths i had to insert mine vaginally after takibg one ib the drs office. I woke up from a dead sleep 3hours after placong the pills internally covered in blood and in so much pain even laying in a ball didnt help. I chose this option again cause thr first time it was like nothing. I would recommend this deffinately but make sure u drink lots of water as for me i threw up the entire 24 hours before internally placing the pills. And take ur pain pills as directed as well goodluck. F 20 1 days
1/6/2012
 4  abortion The first hour or two after taking the four pills I had HORRIBLE cramping. I normally have high pain tolerance, I experienced kidney stones & all that was to me was uncomfortable, but these cramps were really bad. After the hour or two of cramping, it died down to regular period cramps. Every hour I would apply heat to my abdomen which helped a lot. The pain meds didn't really do anything for me but make me sick. It's been 7 days since I took the last 4 pills & I still have heavy bleeding & clotting but overall, it was SO worth it. I would recommend it to anyone in a situation like this. F 19 2 days
1X day
9/21/2011

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