MIFEPREX Reviews (MIFEPRISTONE)

Average Rating: 3.6 (68 Ratings)

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MIFEPREX  (MIFEPRISTONE):  This medication is used to control high blood sugar in people who have a certain condition (Cushing's syndrome), and who have failed surgery or cannot have surgery to correct the condition. Cushing's syndrome is caused by the body producing too much of a certain hormone (cortisol) which can cause glucose intolerance or type 2 diabetes. Mifepristone works by blocking the effects of cortisol.   FDA Approval Date: 2000-09-28 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on MIFEPREX: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR MIFEPREXCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  Medical Abortion Very painful, heavy bleeding, blood pressure dropped low. Having said said that it was over quickly I was tired for a day or two. Would do it again if I had to. Feel my doctor could have told me how quickly the pain came on and how bad it would be but over in a few hours. I wasnt goingto tell my husband but I am glad I did as for a few hours it was bad. M 40 1 days
1X O
2/13/2011
 4  Abortion None. I was satisifed with how well it worked, but waiting two weeks for my follow-up apptmt. to find out if it was complete was excrutiating. Only do this if you can take the wait. Surgery was too scarey for me so if I had to I would go this route again, but I think it works best really early in pregnancy. I was only about 3 weeks preg. Also, please don't do a home preg to see if it worked. You'll drive yourself crazy. My test said positive almost two weeks after taking Mifeprex, although I wasn't preg anymore. My doc said the hormones can hang around for a while so let your doc tell you if you're still pregnant. It will keep you off the emotional rollercoaster. M 36
6/5/2006
 5  Unplanned pregnancy First off, I want to Start by stating that this is a excellent choice for a woman who is doing this for the first time, it basically causes you to have a miscarriage. Day one: I went to a clinic my doctor referred me to, and there they had me fill out paperwork regarding the experience/ consent form. Then I waited in the waiting for a moment(horrified ofcourse) I was called in by the nurse into the room where they gave me a ultrasound. Using a probe. It determined I was 6 weeks and 2 days pregnant. They were able to see on the screen there was a embryo present. I went back into the waiting room, later I was called in to do a blood test to determine my blood type. Then back into the waiting where then a counselor called me in to a office where she had a personal talk about my decision. She asked me over and over again if I was 100% sure about the medical abortion, I assured her that I have never done this before, and that I was to scared to do the surgical. She went over the facts about the pill. Afterwards I went back into the waiting room where I waited 2 hrs. The nurse called my name, I went In to a room where the doctor gave me a pelvic exam to make sure my uterus and everything else is in place. It only took 5 mins. They gave me the first pill to take In the office with ginger ale. The doctor reminded me that cramping may occur instantly or hours later, or maybe after you take the other set of pills the day after. I was sent home. Didn't feel much pain, but was very nausea F 23 1 days
3/13/2013
 5  Medical abortion I did not experience any symptoms until I took the 4 abortion pills roughly 26 hours later. Within the hour I experienced moderate cramping that came in waves and lasted only a few minutes at a time. I passed the sac no more than 2 hours later and the cramping stopped altogether shortly after that. The bleeding also slowed but was never really heavy to begin with. I know everyone's body reacts differently but for me this was virtually painless and I would recommend it to anyone. F 24 1 days
1X D
1/8/2012
 5  Abortion I was told I was about 5 weeks 4 days (based on missed period) pregnant. I believe I was only 3 weeks 5 days pregnant (based on possible conception date) . My sac measured 7 or 8 mm not exactly sure. I took the mifeprex in the drs office felt nothing. No bleeding or anything. 2 days later i went back and the dr inserted 2 tabs of misoprostol (sp?) vaginally. I was told to take 2 more of the same pills by mouth 2 hours later. About an hour before I had the pills placed vaginally i had taken 4 200 mg ibuprophen pills. I felt slight cramping and bleeding about 2 hours after receiving the misoprostol vaginally. It started with the sac passing then bleeding fresh bright red blood. After 2 hours I took 2 more misoprostol pills orally. Just swollowed like normal pills. Then after everything i just bled like a light period. Not even filling my pads all the way. I was worried that i wasnt bleeding enough. I kept taking the ibuprophen every 3 hours id take 3 then the 4th hour id take one more. I didnt want to feel anything !! I also took 1 vicodin which did nothing. I went to sleep after this. The next few weeks i bled like a normal period then i had some spotting. It was a natural experience. Now. Im a Catholic. Grew up Catholic my whole life. Even in pro life clubs and went to the marches yearly in DC. You dont know what its like until you are in a certain situation. You can never judge anyone. I feel stupid for ever wanting these rights to be taken away. I think that every woman sho F 24 1 days
9/15/2012
 5  abortion My doctor prescribed mifeprex to take for the first dosage, and 4 pills of cytotec to take the following day. I took the mifeprex at 4pm, and felt nothing whatsoever. The following evening, at about 10pm I was watching TV on the couch and felt a gush of blood leak out into the pad. I went to the bathroom and sat on the toilet, and immediately started bleeding heavily. There was still no pain, but it was obvious that the abortion was in progress as I could feel the blood clots falling into the toilet. This continued for about 2 hours and then slowed considerably. The next morning, there was still no pain, and one last clot (which appeared to be the grey/white gestational sac) fell into the toilet. This same day at 4pm (48 hrs after mifeprex) I took the 4 pills of cytotec orally and let them dissolve. About 30 minutes later severe cramping begun, but not more than a heavy crampy period. The cramping lasted until about 11pm that night. Bleeding was only moderate during this whole evening, I assume because I had already aborted the day before. My experience with this procedure was an overall 100% satisfaction. I was 6 weeks and 4 days upon taking this medication. F 26 1 days
1X day
8/10/2012
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 5  Unwanted pregnancy I was definitely nervous before going through with this method but, I am happy to say that is was so much easier than I anticipated. I took the first pill at the clinic I decided to go to. I was told I was 7 weeks and 1 day along. I didn't feel any side effects at all except for how I was already feeling (fatigue and nausea) due to the pregnancy anyways. The next day at 3:30 pm I took the 4 mifeprex pills (2 in each cheek for 30 mins to dissolve) as told. I was pleasently surprised that they did not taste like anything so it made it much easier. After the 30 minutes I drank some water to swallow what was left and immediately threw up. I think it was due to the consistency of the pills. About 2 hours later I felt a gush into the pad. I bleed heavily for about the next 4 to 5 hours. The most uncomfortable thing of the whole ordeal was everytime I sat on the toilet large amounts of bloodclots gushed out which freaked me out feeling. My cramps were minimal, I had taken the pain killers beforehand which definitely mustve helped. At about 11:30 pm the bleeding almost completely stopped and was like a light period. Next day I felt kind of tired from being up late but very relieved and much better. This is a great choice for anyone wanting to do this in the privacy of their home and very worth it. F 24 1 days
1
10/12/2012
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 5  Medical Abortion Vomiting, Severe Cramps, Uncontrollable Shaking I felt nauseated after I took the first pill at the Dr.s office and was very reluctant to take the other 4 pills because of everything I read about the drug. 24 hrs later I took the 4 pills in my cheeks and waited. About 1 hr later the Cramping started. I cannot take Vicodin because it makes me sick so I asked the dr. to prescribe me something else so he gave me Tylenol 3 with Codeine. This was the worst mistake. The tylenol kept wearing off during the whole ordeal which lasted 12 hours and was very painful for me. I couldnt stop shaking and during the most painful moments I was walking around my living room in circles crying because the pain was so bad. I also was breathing just like I was in labor. It was terrible. Throughout the whole ordeal, I bled very little and at about the 4th hour the sac came out but I was still in pain and had severe cramping for the next 8 hours. I finally was able to fall asleep and the next day I just felt really sore. Overall, Im glad that it is over and it worked.The only advice I can give is take the strong pain pills. I feel like it would've been a more tolerable experience if I would've just listened to the Dr in the first place with the Vicodin. F 27
1X day
11/12/2012
 5  Medical Abortion Felt weak. Heavy, heavy , heavy bleeding At 5 weeks I took the one pill on a Friday then on Saturday exactly 24 hours after taking the first pill I took the remaining 4. Two on each side of the cheek and let it stay for 30 minutes then swallow the rest. I waited an hour then took some percocet and I felt no pain. The bleeding and bloodclots however where alot. It is day 6 and I am still bleeding but not as heavy. Other than the heavy bleeding this is way better then going to the clinic and having it sucked out. It cost more but it is worth it and especially in the comfort of my own home and help. F 31 2 days
1X day
3/11/2011
 5  unwanted pregnancy in its 7th week Slight to moderate cramping which lasted for about an hour and a half. I was expecting the worst after all the horror stories I read online about Mifeprex but it turned out that I had stressed over nothing and the procedure was surprisingly not only tolerable but rather painless. I took two different strong painkillers half an hour before inserting the two misoprostol tablets vaginally, and experienced some slight cramping (I've had sharper and more painful menstrual cramps in past periods) which I napped through. When I woke up, I ate some breakfast and then over the course of the next two hours, I expelled a bunch of blood and clots with each trip to the toilet. The bleeding seemed excessive at first and came in big gushes at a time but according to the nurse I talked to it's normal. The bleeding tapered off significantly by the afternoon. I was so relieved afterwards how smoothly things went and was glad that my doctor talked me into this instead of the surgery. F 27 3 days
1/28/2010
 5  early pregnancy termination minimal nausea and fatigue with the Mifiprex, moderate, but not intolerable cramping with the misoprostol I was very nervous about taking the misoprostol based on ratings here and other sites. Here is my experience: 5 pm- took Iburofen 800mg, 6 pm- took Percocet and Zofran (nausea), 7 pm- took misoprostol, allowing to dissolve in cheeks for 45 min, 8pm- mild bleeding, 10 pm-2 am- able to sleep, mod cramping, (feeling like I had the breath knocked out of me, in a way) took 2 more Percocet and 800 mg IBP. 9 am- cramping done, still had some bleeding with clots, but not painful. Much less traumatic than I expected, very little pain. I feel tired today, but am able to be up and about. F 37 1 days
1X day
5/3/2010
 5  abortion i guess everyone is different, but i had very little pain form this. it was like a heavy period to me. i was 6 weeks 3 days. i had a little nausea the morning after taking the dose at the office, then on the 3rd day did the 4 pills vaginally to dissolve. about an hour later i had some mild cramping and passed blood clots for a few hours but that as well as the crampling stopped with in about 5 or 6 hours. it is now day 5 and i still have some light bleeding but i feel good. i was very thankful that i was about to have a medical abortion instead of surgical. do what is right for you. dont believe all the horror stories online. just talk to your doctor and i am sure they can let you talk with some REAL people who have taken it. good luck to all. i know it is scary but you will make it thru everything. F 32
1X day
5/25/2010
 5  abortion almost none. biggest worry was throwing up which i experienced a couple times a day. only very mild cramping and very brief bleeding and passing of bloodclots. didnt even take the prescription pain meds, just 2 advil and still felt alright. F 19
1X day
7/13/2010
 5  Pregnancy Termination I took Mifeprex on day 1, on day 3 I was instructed to place the 4 remaining pills in my mouth on the inside of my cheeks where they would dissolve for a half hour, then I swallowed what was left of the pills. After washing the pills down with water, I threw up violently all of the water and my body insisted I keep throwing up when there was nothing left to give (due to nausea in the first place). About 30mins later I started to experience the worst pain I have ever felt in my lower stomach and staggered hunched over to the bathroom where I immediately started to bleed in the toilet. I waited on the toilet for as long as my body would allow me to sit upright and flushed without looking. I was sweating heavily but was freezing at the same time so I wrapped myself in a towel. Back in bed, I could not get comfortable. I tried turning on each of my sides in a fetal position and nothing helped so I frequently changed positions, wincing in pain, and squeezed the covers around me tight. !!!PLEASE READ FIRST!!! MY PHYSICAL CONDITION LEADING UP TO MIFEPREX: During my 6th week of pregnancy I was very nauseous everyday. I had only been able to eat small portions of blan foods such as pretzels and was drinking chicken broth and water the week prior to taking Mifeprex. Still, I think my body was very weak and dehydrated which may or may not have contributed to the side effects. I strongly suggest gatorade and pretzels or crackers, they were my only comfort during this process. Also get at least two days off from work during the bleeding. With as much pain and discomfort I experienced, I do not regret my decision for taking Mifeprex and would recommend it to others. It was difficult but I felt 100 percent better in the following days. F 23 3 days
1X day
8/12/2010
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 5  pregnancy termination Four weeks pregnant: One strong contraction with a gush of blood accompanied by diarrhea. No other problems. This review written 31 hours after taking misoprostol. After all the terror I suffered preparing for this ordeal (my first experience with birth control failure, religious upbringing, etc) I'm so happy. Day one I took the Mifeprex in a clinic. I asked for pain and anxiety meds. I felt great for the next two days, no side effects. After ~52 hours, I took a Vicodin, waited 30 minutes, placed the misoprostol between my cheeks and gums. One note - I only weigh 100 pounds so I took the liberty of reducing the dose from 4 to 3 pills without consulting a clinician. I was afraid of the severe pain I've heard of others experiencing. The 3 pills took an hour and a half to dissolve, which I didn't expect, therefore waited that long to take a 600 mg ibuprofen chaser. Even after that, I felt only minor lower abdominal cramps, and was so comfortable I got hungry on hour three and went out to dinner. Luckily I wore a pad because as soon as I began to eat I had to run to the bathroom as it felt like I had diarrhea. For about 10 seconds on the toilet I worried because it was really bad cramping, but it went away as fast as it came. I went home (finished my food!)waited for anything bad to happen, but there was just bleeding when I sat on the toilet. At about 11 hours, I woke up and took 2 Advil for minor cramping, and went back to sleep. I then got up and went to work this morning like a normal day. Have had clots and thick bloody discharge when I pee but minor spotting on the maxi pad, no pain. Feeling emotionally better than I have in 2 weeks. F 38 1 days
1 1X day
3/14/2011
 5  Abortion After the Mifeprex, I felt nothing until about 17 hrs later. Then, heavy bleeding began, but it was painless. At 7 wks, 3 days. I took a Vicodin and over-the-counter nausea medication at 7:45pm after eating a full dinner. At 8:35pm, I placed the 4 cytotec pills in my cheeks and spit them out at 9:05pm. Felt nothing until 9:25 when I felt moderate cramping and ran to the bathroom to throw up. Lost my dinner. The cramping got stronger and was painful, but bearable. Some light diarrhea and fever-like chills/sweating followed that was short-lived. I heated a water bottle for my abdomen, was drinking lots of water to replenish, and curled up with the bottle in bed around 10:30 and was able to sleep. The cramps had lessened. I woke up at 1:45am with heavy bleeding, clotting and mild to moderate cramping and sweating again. I took 1 more Vicodin, drankna bunch of water and went back to sleep for hours. I woke up with no cramps or nausea, just bleeding. Is this an unpleasant experience? Yes. Was it bearable? Absolutely, and it was completely over after a few hours. There is no more "humane" way to have an abortion. Abortion is inducing early labor and expelling a fetus. That being said, I'd recommend this process to a woman considering abortion and would tell her that she will be fine in no time. F 27 1 days
200mg 1X day
4/8/2011
Email
 5  Medical Abortion I took Mifeprex on a Thursday afternoon. By Friday afternoon I was very nauseated but was able to work through it all. About 30 minutes before I took the misoprostol I did throw up but I think it was from me taking my antibiotics on an empty stomach. After putting the Misoprostol in my cheeks I was hit with another wave of vomiting and barely kept the misoprostol in my cheeks. After throwing up about a dozen times I was fine and went and laid on the couch with a heating pad. I fell asleep for about 2 hours and woke up with some moderate cramping and had a mild urge to push. I did and passed the sac. I am only about 6 weeks along and the sac was the size of a golf ball. It was pretty obvious it was the sac as it was a light gray color and very different than the other clots. I've continued to have mild cramping but nothing unbearable. I've only needed to take pain meds once. I pass a lot of clots when on the toilet but barely any on the pad. This was by far a better option than surgical and much less painful. Well worth the additional price! F 28 3 days
200mg
12/3/2011
 5  Medical abortion Cramping, gas, nausea and vomiting, HEAVY bleeding. F 20 1 days
3/7/2012
 5  abortion i was given the drug at the abortion clinic. everything was fine. however i took it on an empty stomach and kinda felt dizzy after. then i took misoprostol 4 total inside of my cheeks. let it dissolve inside of my mouth. after an hour of taking it i threw it up. was real scared that it wouldnt work but it did. all of a sudden i got really bad shakes and HORRIBLE abdominal cramps as well as sharp back pains. it felt like contractions. i delivered a child before and know how it feels. the pain felt unbearable!!! i took 2 ibuprofens and it did NOTHING for me! i continued to toss and turn in my bed. then the bleeding came...it was really really heavy. i soaked in 2 pads in an hour. looked thick and buncha blood clots came out. i laid back down and put a warm pad on my belly. then the pain came back even worse then before. i felt a strong urge to push. ran back to the bathroom and as soon as i sat down something heavy came out of me. i got up and seen the baby sack. it was as big as an actual egg. everything on the inside of it was see through. i hunched over the toilet and cried. this is not for the faint of heart...it took me by surprise. after i put myself together i laid back down and the pain stopped within the next hour, after that light bleeding of blood clots but not like before. overall the drug did what i needed it to do... F 27 1 days
1X day
1/3/2012
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 5  unwanted pregnancy slight cramping (no worse than normal menstrual cramping), very little stomach discomfort. I went to the Houstons womens clinic and recieved ru486 after only a little research. when I came home I thought i would take a look at what other people thought of this drug and after reading just a few comments i was so frightened. People wrote of horrifying experiences and i was so nervous about the rest of the medication i had left to take over the next few days. But i made myself calm down to ensure that i didnt experience anything psycosamatic and i finished the drugs with no pain and very little discomfort. I am so pleased with the effects of this drug. I am beginning to believe that the only people that write on these bulletins are those who want to scare you away from abortion. F 19 4 days
8/10/2007
  

MIFEPREX  (MIFEPRISTONE):  This medication is used to control high blood sugar in people who have a certain condition (Cushing's syndrome), and who have failed surgery or cannot have surgery to correct the condition. Cushing's syndrome is caused by the body producing too much of a certain hormone (cortisol) which can cause glucose intolerance or type 2 diabetes. Mifepristone works by blocking the effects of cortisol.   FDA Approval Date: 2000-09-28 (Sources: U.S. Centers for Medicare Services, FDA)

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