MIRAPEX Reviews (PRAMIPEXOLE DIHYDROCHLORIDE)

Average Rating: 2.8 (431 Ratings)

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 EXTRAPYRAMIDAL MOVEMENT DISORDERS

 Type: Rx Drug

  

MIRAPEX  (PRAMIPEXOLE DIHYDROCHLORIDE):  Pramipexole is used alone or with other medications to treat Parkinson's disease. It can improve your ability to move and decrease shakiness (tremor), stiffness, slowed movement, and unsteadiness. It may also decrease the number of episodes of not being able to move ("on-off syndrome"). This medication is also used to treat a certain medical condition (restless legs syndrome - RLS) that causes an unusual urge to move the legs. Symptoms usually occur at night along with uncomfortable/unpleasant feelings in the legs. This medication can decrease these symptoms and thereby improve sleep. Pramipexole is a dopamine agonist that works by helping to restore the balance of a certain natural substance (dopamine) in the brain.   FDA Approval Date: 1997-07-01 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR MIRAPEXCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  It was the only med that worked After I had been taking Mirapex for about 3 years, at gradually increasing dosages, I started gambling. I did not connect this to the Mirapex until I read some things on the Internet recently, but previous to the onset of this compulsive behavior I had been very proud for years that I had never gambled, and that I had never even played the lottery. I have also been diagnosed with sleep apnea (severe) and have increased weight, but do not know if Mirapex is the cause of those things. For many years, I called Mirapex, my "miracle" drug, but now I am not so sure. I don't know what to do though, because I have an advanced case of RLS, and I can't live without a medication to relieve those terrible symptoms. By the way, I describe it to others in this way: It is like I am a human capacitor, and I can feel an electric charge building up in me, which then discharges causing my body to spasm. But it feels as if there is an almost constant low electric charge going through my body. It is terribly uncomfortable. M 55 8 years
4.5 MG 1X day
6/7/2010
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 5  RLS No side effects that are apparent to me. If I do not take mirapex exactly at the same time each night, my restless legs will begin and I am reminded how intolerable the syndrome is to my quality of life. I too, was diagnosed with RLS, before it was widely accepted by doctors. It was a neurologist who prescribed it for me and I cannot imagine what life would be like without this drug. I am concerned about compulsivensss but I honestly can say that I loved shopping as much before mirapex as I do now. F 55 15 years
1.5 MG 1X day
6/6/2010
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 1  Parkinson's Disease I'm writing this about my uncle who we are trying to get off Mirapex right now. He has had almost every side effect. The scariest so far being the change in attitude. He has become a sexual deviant who has a "girlfriend" who i learned is actually a prostitute. He has also gone through about 50 thousand dollars in the past year on what i believe to be gambling. He is no longer the kind old fashioned man who was like a 2nd grandfather to me. Please make sure you have friends and family watch you if you are on this drug. It messes with your brain and changed the person you are. Keep an eye out for strange behavoir with loved ones taking this. It may do some good but they must be monitored. If your thinking about taking this. Please dont. Its far too hard on your family if you end up with serious side effects. THERE ARE NO CURES AND MIRACLE DRUGS. DONT EXPECT IT TO BE. BEWARE ANYTHING THAT MESSES WITH YOUR BRAIN CHEMISTRY !!!! M 25 3 years
1X day
4/26/2010
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 3  restless legs Mirapex has helped my legs. I have had increased compulsiveness (mostly eating), water retention, songs stuck in my head, trouble concentrating and a feeling that I am just not myself. Not completely sure if all of these side effects are due to the Mirapex. I am still not sure if all of the side effects are due to the drug (my doctor says the dose is too low to be experiencing some of these things). I would be interested in hearing from anyone who has similar side effects on a low dose. I am trying to wean myself off the Mirapex to see if some of these symptoms go away. F 47 8 months
.125 mg 1X day
4/2/2010
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 5  RLS I have noticed an increased interest in sex especially for a 77 year old man Th benefits of Mirapex completely relieving my RLS syptoms far outweighs any negative side effects. M 77 5 years
2 MG 1X day
3/25/2010
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 2  Parkinson At first,no side effects.very vivid and wierd dreams, disoriented, a vague feeling of being disassociated. I've gained 42lbs . when I go off it I to am like a shakey wobbley old lady. This drug has caused hell to everyone I come in contact with. It got worse overtime the longer I take it.I am hungry all the time. obsessed with shopping and would buy things I couldn't afford. I am very suspicious of my husband, no trust in him. my mind is so clouded that I believed I am right and everyone else was wrong. My concentration and decision making is a total mess. compulsive computer use; restlessness - need to be active; tired all the time, but can't rest; all of these behaviors are totally new to me - I don't like having these feelings.compulsive gambling! started mirapex on lowest dose it worked great but had to increase to 1mg. after about a yr. Then the gambling started and became gradualy uncontrolable. I have to try to overcome this terrible compulsion, slight memory problems. But the I ditto many comments so I cut and pasted and altered them in my side effects. Will Someone - please tell me what are the alternatives!!! F 58 6 years
1.5 3X day
3/10/2010
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 2  parkinson's disease I am writing on behalf of my 49 year old mother. This drug has caused hell to everyone in our family. It got worse overtime the longer she was taking it. She gained about 40 lbs and she was hungry all the time(thats not the severe part). She was obsessed with shopping and would buy things she couldn't afford and just return them. She repeated this behavior 24/7. She would redecorate the house constantly! She started to get extremely paranoid and suspicious of EVERYONE! She trusted no one and thought everyone was out to get her! She did was abit delutional also. My dad divorced her over this was he couldn't take it anymore. Her mind was so clouded that she believed she was right and everyone else was wrong. She concentration and decision making was a total mess. It was like giving direction on common sense situations to a 13 year old. Her sex drive was out of control to the point where she wanted it so much that she even slept with my friends boyfriend( something she would If anyone feels any of this feel free to email me if you have questions. My email is [email protected] F 49 5 years
1 mg 3X day
2/26/2010
 2  RLS At first, I had no side effects. Until reading this forum, I thought I was coming down with Parkinson's because I have a chronic shake! I don't drink or smoke and eat well, healthy life style. Now I shake, I have chronic headaches, very vivid and wierd dreams, disoriented, heavy night sweats and a vague feeling of being disassociated. I've gained weight and it only helps my RLS a little. I think I'll go off of it and just exercise my RLS away, gotta be better than walking around like a shakey old lady. I usually only take 1/2 of .25 mgs, still have many side effects. Tired of the shaking and headaches. F 52 6 months
.25 1X day
2/3/2010
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 5  Sleep Behavior Disorder Possible weight gain.....I take a lot of other meds also:-( Has really helped, along with klonipin, to keep me from acting out my dreams. Consequently I now get a good nights sleep. F 52 5 months
1/28/2010
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 3  RLS Try taking Tonic Water or Quinine pills instead, I do not want the weight gain or the nightmares within 5 mins of FIBNA::Y drifting off to sleep!!! F 50 1 days
1/20/2010
 5  RLS Some numbness on the bottom of my feet, between the 2-5 toe, but nothing inhibiting any activity. I found that when sitting on an airplane, if the rls started kicking in, I could take a mirapex, and within 20-30 minutes the symptoms were gone. It was a great help since walking around in flight isn't an easy task. It was only after taking mirapex that I was able to get a restful period of sleep at night...after about 15 years of complaining to doctors. My RLS started as I was going through menopause. That wasn't a surprise, because during both my pregnancies, I also had RLS symptoms that would go away as soon as I delivered. Of course, nobody called it RLS at the time...they just looked perplexed when I described the symptoms, and tied my feet with strips of fabric! for relief. In August, 2008, I had to start a very aggressive cancer chemotherapy program, and the mirapex seemed to lose its ability to control the rls. I had to find other medicines to control it during that time. F 68 6 years
1/18/2010
 4  RLS None Wake more rested. F 56 9 years
1/10/2010
 3  Parkinson's Disease Extreme weight gain 40+; sleeplessness; compulsive eating (espec. in middle of night); compulsive computer use; compulsive shopping; restlessness - need to be active; tired all the time, but can't rest; all of these behaviors are totally new to me - I don't like having these feelings. I take mirapex in conjunction with stalevo and it has controlled the tremor associated with PD. I hate the side effects, but continue to take it because I don't want the tremor to return. I wish there were a natural alternative. F 61 4 years
1/5/2010
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 2  PLMD severe Worked to help with sleep....but the side effects make it unacceptable. I have gained 30 pounds/ have obsessive need to keep busy....can't relax...edgy...irritable....am going to MD this week. This drug helped my PLMD, but has made me feel like someone I don't recognize. Have been off/on Mirapex several times over the past ten years. Have reduced my dosage to 1mg. I could almost accept the obsessive cravings for sweets and the accompanying weight gain; can no longer accept the personality changes.....edginess....irritability....compulsive shopping/computer use etc. F 63 8 years
1/2/2010
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 1  RLS Woke up groggy with the worst sinus congestion I have ever experienced; horrible headache and neckache; weakness in limbs; nausea. This scared the heck out of me - I only took a very small doseage because I am so tired of RLS symptoms. I did feel, for the first time in years, my body totally relax and the RLS vanished - NOT WORTH IT! When I woke up, the side effects started. Thank God I found this website - I'm just now coming out of it - the half life time is about 12 hours for someone my age. I'm on my way to the health food store to see if there are any natural ways to help control RLS. F 64 1 days
12/28/2009
Email
 5  RLS Very vivid dreams, but would not classify them as nightmares. This drug has been wonderful for me. I now am able to cut the .25 mg doses in half, and combined with alcohol (which is probably not a great idea, but I'm a drinker) I always get a good nights sleep and no rls symptoms. M 60 8 years
12/15/2009
Email
 5  RLS Before taking Mirapex, I never remembered dreams. Now, not only do I remember dreams, they are very detailed and vivid. In addition, I've had nasal congestion since starting the drug. Mirapex has completely resolved my RLS symptoms. However, I do have to take it regularly (at the exact same time every night and at least 2 hours before going to bed) for the RLS symptoms to not occur. F 23 3 months
12/4/2009
 1  RLS compulsive gambling! started mirapex on lowest dose it worked great but had to increase to 1mg. after about a yr. Then the gambling started and became gradualy uncontrolable. I have to try to overcome this terrible compulsion, I have a drs. appt. but not for another 2 weeks, I pray he can give me something else to relive the rls as it is the most miserable pain I'v ever experienced. I also have dizzeness, nausa, slight memory problems. But the gambling is running my life. Ican't deal with the self louthing as well as the finacial devistation after a binge (for lacke of a better word) I saw the warning this med causes but thought gambling,thats crazy. Take the warnings serious. DO NOT START THIS DRUG!!!!!!! F 57 2 days
11/18/2009
 1  Parkinsons Compulsive drive towards non-typical behavior which seems to circumvent rational oversight and sense of responsibility. As a result, my wife is now considering divorce. I would like to communicate with someone who has also experienced this compulsive drive to understand if your experience is similar to mine in the sense of how much conscious control we have or does it circumvent \ bypass the normal thought mechanisms. Your help could help me save my marriage so thank you in advance. M 53 4 years
11/16/2009
Email
 1  RLS Severe weight gain 50+ excessive sleepiness during day, incontinence Worked for the RLS but didn't figure out the problems I experienced were from the medication until I did research on the Web. I would never take this again. F 53 1.5 years
11/12/2009

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