MIRAPEX Reviews (PRAMIPEXOLE DIHYDROCHLORIDE)

Average Rating: 2.8 (431 Ratings)

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 EXTRAPYRAMIDAL MOVEMENT DISORDERS

 Type: Rx Drug

  

MIRAPEX  (PRAMIPEXOLE DIHYDROCHLORIDE):  Pramipexole is used alone or with other medications to treat Parkinson's disease. It can improve your ability to move and decrease shakiness (tremor), stiffness, slowed movement, and unsteadiness. It may also decrease the number of episodes of not being able to move ("on-off syndrome"). This medication is also used to treat a certain medical condition (restless legs syndrome - RLS) that causes an unusual urge to move the legs. Symptoms usually occur at night along with uncomfortable/unpleasant feelings in the legs. This medication can decrease these symptoms and thereby improve sleep. Pramipexole is a dopamine agonist that works by helping to restore the balance of a certain natural substance (dopamine) in the brain.   FDA Approval Date: 1997-07-01 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Date added.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR MIRAPEXCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  treatment resistant depression none went off of Mirapex for just a few days (to try a different yet conflicting med), extreme suicidal thoughts and was ready to self-admitt to be hospitalized. Went back on, was fine. F 33 2 years
0.75 3X day
11/10/2010
 3  RLS Weight gain, compulsive behavior I started with .25 mg and I am now at 1 mg. It really helps with the severe RLS. But I once again need to increase to a higher dosage, it is not working. I am afraid to increase dosage due to compulsive shopping and gambling issues, and severe weight gain. But I am afraid to stop the medication due to severe RLS. F 45 4 years
1 mg 1X day
11/1/2010
 4  for restless legs None I actually only take it every 3 days. It has helped me that much. F 63
30 mg 1X day
10/4/2010
 5  Fibromyalgia, Parkinson's Some weight gain (5-8 lbs) that seems to have stopped since I no longer want to eat too often, Some excess sex drive and romantic inclinations that are annoying, Some sleep problems at night and drowsiness in afternoon. First med that I have tried (out of many over the past 10 years) that actually took away the fibromyalgia pain. It fixed moderate bradykinesia and stiffness. It seems to have helped flagging memory and cognition to some degree. It also seems to have enhanced stress tolerance and boosted low self-confidence. I think it is important to not take too high of a dose - increment and wait until your system has adapted to current dose before incrementing again. Avoid eating protein within an hour of taking the pill. F 38 60 days
0.25 2X day
9/30/2010
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 2  RLS, FBM Intense sleepiness (all day, short 2-3 hours deep sleep 4-5 times per day), vivid and anxiogenic dreams, nausea, slight fever, skin reaction (red), lack of concentration, and... increased RLS and FBM symptoms Sleep much better, but too much, and the side effets are so unpleasant that I stop after 4 days. It is not fun to be uncomfortably numb! M 48 4 days
0.125mg 1X day
9/22/2010
 1  spouse has Parkinson's For the first almost three years Mirapex was working well. Side effects were minimal, as the initial dose was .5 mg three times a day. In May 2010 it was increased to 1 mg three times a day. By August 2010 sexual urges increased drastically. Every toy imaginable was bought. Erectile dysfunction but it didn't stop the sexual urges. By the end of August the cross-dressing started. This has been totally affecting our relationship. I will not accept it. One week ago he stopped taking Mirapex, per his doctor's decision. When will symptoms beging to subside as they still are very strong?????? We are both receiving therapy for this. This is not what I wanted to have happen to our relationship. He is now telling me he is unsure if it is a side effect for him or it is a new part of his life. F 58 3 years
1 mg 3X day
9/21/2010
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 3  RLS OCD, irrational irritation, hallucinations, concentration problems, falling asleep(narcolepsy), extreme sweating with sweet vanilla scent, swollen feet with discoloration, weight gain. I increased the dosage about 2 years ago and 1.5 years ago I lost my job with a very prestigious university because of the side effects. I was not even aware of that I had side effects until I read the comments on this site. I need to get in touch with others that have taken legal actions, please email me if you are taking legal action. M 43 10 years
2.8mg 1X day
9/20/2010
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 1  RLS All the crazy behavior listed. My answer was Abilify. My psychiatrist first thought I was Bi-polar based on my behavior. Once he realized I was on Mirapex, he immediately took me off and started Abilify at 5mg. It has something in it that helps the RLS. Once it was in my system he reduced the dosage to 2mg every other day. About 2 weeks after I stopped the Mirapex, I realized that the fog had lifted and I started to feel normal again. F 48 5 years
1 1X day
9/15/2010
 2  Parkinson's I am writing for my husband, who was taking Mirapex for Parkinson's and RLS. He soon began having blood pressure drops, causing him to fall into a deep sleep to the point of my having to call 911 to revive him and take him to the hospital. After several days, they released him, with no explanation as to what was happening. His cardiologist could not regulate the highs and lows of his blood pressure, since he was experiencing both to the extreme, so one medication was counter-acting the other. He was beginning to fall asleep in his food every time he ate. His Parkinson's doctor put him on Mirapex ER once a day, hoping that would better regulate the meds, as he wasn't good at taking it properly. Until then, he was still able to be out doing some things around the farm. When his BP dropped one morning to 49/32, I phoned and told his doctor that the Mirapex seemed to be dropping it too low and he immediately took him of all Mirapex. For the next 2 weeks, he was falling into a deep s When I checked the warnings on the Prescription print-outs, there it was. Not the BP part, but the falling asleep part. I can't believe that not only the doctors, but myself as his caregiver, had missed that for so long. It could have killed him. He is doing well now, except for the RLS, which came back with a vengeance. He is on Neurontin for that, but it isn't controlling it during the night.I would only recommend this drug if ALL the warnings were conveyed to the patient by the doctor and that the doctor was monitoring all of them faithfully. I cannot believe that our PCP, our Cardiologist and our Neurologist all knew what was going on with him and that he was taking Mirapex, but not one of them connected the two or the gravity of his situation. M 85 5 years
25 3X day
9/4/2010
 2   I echo everyone here with the side effects. Shopping, obssesive internet activity, not able to focus, depression, weight gain etc... Starting with 1mg, I slowly lowered my dose to .25 & if needed, I add in .12 increments, & the lower dose has helped with the side effects; but they are still present. I am trying natural remedies such as Leg Calm & Mind Soothe to get off of Mirapex & have gone on a low carb diet, not no carb, but low carb. I have lost 4lbs. in 5 days which is just water but is a start. I already feel a lot better. I also walk 4 times a week (at least) & eat fresh, not frozen or canned, produce; fish or chicken only 3 times a week...no red meat. Today is my first day with the natural remedies & I am very calm & will see how tonight goes. I'm on a quest. I'm suffering as are all of you with Mirapex changing our personality to the point we don't know who we are & for some of you, no longer recognizing your loved ones. This is not acceptable. I'm not medically trained; just someone willing to experiment & determined to throw my Mirapex down the toliet. F 55 2 years
1mg to .25 1X day
8/31/2010
 4  Restless Leg Dullness of thinking, fatigue, increased headaches, ebay obsession for a while, eating excessively, weight gain, more vivid dreams, anti-social feelings (want to be left alone, not interact with people) I've had RLS for about 20 years. Think my father had it, too. As many of you know, back then the doctors did not know anything about RLS. About 15 years ago, my husband went to a "sleep doctor" told her about me and she prescribed Mirapex. The .25 mg pill did not do the job, so I started taking 1.5 pills. Then that was not enough. Now I am taking .50mg, but finding I have a headache every day and feel more fatigued. I am going back to the 1.5 pills. I have found I must take it about 5:30 pm everyday. The more I eat, the less the pill works. This should be a good way to diet and I must really do that. I do have vivid dreams, but I always did have dreams, even with color. However, I've noticed my dreams now are more stressful, which is another reason to go back to the lesser amount. If I am really involved in an activity and forget my pill, which I frequently do, when I take it later, it takes hours to kick in. I like to paint. I find when I have taken the mirapex, my "creativity" goes downhill. All in all though, I must learn to recognize the bad side effects and deal with them. I would have a miserable life if it were not for Mirapex. F 69 15 years
.50 1X day
8/22/2010
 3  Severe RLS / PLMD I gained 48lbs with one year of starting this medicine. Year two I noticed water retention, headaches, and chest discomfort which I mentioned to my doctor. ECG was normal. After four years I have strange dreams, daytime hallucinations, behavioral changes, heart rythym disorders and insomnia. My symptoms before taking this medicine were so severe that I was existing on an average of 2 1/2 hours sleep a night. I was barely able to function. My symptoms started about noon and continued throughout the day and night. Mirapex controlled the symptoms and seemed like a miracle at first but now, I'm looking for an alternative as I am spending money like there's no end to it, unable to stay asleep, exhibiting OCD tendencies, short term memory loss, disorientation, slacking responsibilities, and having fits of rage and/or crying that I can't control. I guess the miracle is over. F 57 4 years
.75mg 2X day
8/22/2010
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 5  RLS and Fibro none has worked great! F 51 2 years
0.25 1X day
8/2/2010
 4  RLS Frequent urination at night. Every half hour or so. Vivid dreams, exhaustion during days when meds do not work. muscle cramps in legs infrequently, tics. Nausea and the spins only when taking max does of 4 pills. I would not stop using this drug. Tried the other drug for RLS and side effects were insane. Vomitting, flulike symptoms nausea. This drug still does not totally stop RLS but helps make it less frequent. F 44 1 years
30MG 1X day
8/2/2010
 4  RLS No known or noticed side effects. However I think I may be developing a tolerance to this current dosage, I am experiencing more bad nights. I may need to talk to my Dr. about increasing the doseage. Meripex is the only thing I have found that has given me relief of my moderate to severe RLS. Before meripex I spent MANY sleepless nights walking the floors and walking outside and taking several hot showers, while holding down a full time job (in law enforcement). With Meripex, I was able to sleep and rest and be norml again. Now I am having trouble with my legs again, I may need an increased doseage. F 61 2 years
.25 1X day
7/22/2010
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 3  Taking for restlessleg and sleep I Have noticed I am acting out my dreams more often than normal,now, once to 3x a night, from about one to two times a month before,(befor Mirapex.) Very vivid dreams,with lots of physical activity,standing,reaching, grabbing kneeling,clearing off my nightstand,talking,arguing,grinding teeth.Luckily I have not left my bedroom during these activities.I have read one others posts that it seems to go away after a short while,"I'm not so sure."I did a little research yesterday and saw that hallucinations were a possible sideffects,witch I was also unaware of, but slightly relived.I have been seeing (what seems to be transparent like objects or things) like something's their but ,it's really not.Like bugs crawling around, or people passing by, that are not their.This medication was intended to help me sleep, the one positive thing I can say is it dose make me sleepy,but you do really need 8hours of real sleep to let this drug wear off. F 28 4 months
.75mg 1X day
7/6/2010
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 3  RLS Helped RLS in the initial 20 days , after that I was nort sleeping at night , falling asleep during day , vivid dreams, lots of shopping , compulsive behavior ,increased sexual drive , having sex non stop , my boyfriend could not keep up. slight headaches, binging cravings at midnight , but once i fell asleep all was ok legs were ok , Some muscle weekness in legs during day. all in all it is a 50/50 lots of side effects but the RLS would go away. F 48 60 days
0.125 2X day
7/5/2010
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 1  parkinsons I had hallucinations but I could handle that. I had a very high desire for sex that I thought was normal but over the past year I have found that I fantasize and even try to act on some that I know is wrong. If I don't get off now I know that it is going to ruin my marrage , family and life. I have always been respected but that is going to change if I don't get off this this med. Right now my marrage is the at risk. Will I lose this addiction when I get off or what can I expect? does any one know? M 64 4 years
.25 4X day
7/4/2010
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 1  PARKINSONS DISEASE first of all the doc told me it would slow the progression of PD! then I started falling asleep suddenly while driving, then I began gambling, and up until then, I hated gambling! then I went through a divorce, lost my family! lost my mind, horrid horrid bad drug!!! I hope the makers of mirapex are put out of business! insane assylum drug! warning... F 30 2 days
1X day
6/25/2010
 5  restless legs Never had a problem or a side effect Wonderful - wouldn't be without it. F 49 6 years
.10 mg 2X day
6/8/2010
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