MIRAPEX Reviews (PRAMIPEXOLE DIHYDROCHLORIDE)

Average Rating: 2.8 (431 Ratings)

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 EXTRAPYRAMIDAL MOVEMENT DISORDERS

 Type: Rx Drug

  

MIRAPEX  (PRAMIPEXOLE DIHYDROCHLORIDE):  Pramipexole is used alone or with other medications to treat Parkinson's disease. It can improve your ability to move and decrease shakiness (tremor), stiffness, slowed movement, and unsteadiness. It may also decrease the number of episodes of not being able to move ("on-off syndrome"). This medication is also used to treat a certain medical condition (restless legs syndrome - RLS) that causes an unusual urge to move the legs. Symptoms usually occur at night along with uncomfortable/unpleasant feelings in the legs. This medication can decrease these symptoms and thereby improve sleep. Pramipexole is a dopamine agonist that works by helping to restore the balance of a certain natural substance (dopamine) in the brain.   FDA Approval Date: 1997-07-01 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by length of time drug was taken from shortest to longest duration (reviews with no time reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

Page: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22


RATING  REASONSIDE EFFECTS FOR MIRAPEXCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  restless legs unsure since I am taking other medications such a blood pressure.Tremblings?/overall weakness? M
9/13/2008
 5  no M 28
6/10/2009
 4  for restless legs None I actually only take it every 3 days. It has helped me that much. F 63
30 mg 1X day
10/4/2010
 4  Restless Leg Syndrome Compulsion to purchase items in general but I can control it. I have severe RLS so that without drugs I stay up 24 hours a day and spend most the time pacing because I cannot even sit down. With Mirapex taken at night and other medications during the day I am able to lead a normal life. Without sleep I cannot work or enjoy life at all. Mirapex has been the only drug that allows me to live a good life. I probably should give it a 5 but I am giving it a 4 because of the fact that it gives some people compulsions such as I have with it. M 57
.50 mg 1X day
12/16/2012
Email
 3  PLMD Initially while adjusting my brain felt Took Sinemet several years. On Mirapex over a year. Couple months ago went for weeks sleeping 2-4 hours a nite. Has improved again, 4-5.5 hours is norm. Take 1.5 in late eve and another at bedtime. My PLMD has progressed to flailing wildly even when dozing or just relaxed. Reluctant to switch meds due to torment during transition. F 53
11/18/2004
 3  Parkinson's Disease Sleepiness (often fall asleep at the computer), nausea,ankle edema, constipation, joint pain. I've been on mirapex for about a year now and I really don't see much difference. My biggest problem with the PD seems to be my typing and hand writing. The mirapex hasn't seemed to help this at all. F 73
4/23/2004
 3  
4/28/2004
 3  Re-Boost SSRI effect The usual stuff at first: Sleepiness, followed by suicidal thoughts probably due to panicky feelings. Then I get hyper. Mood definitely stabilizes. It's just the jitteriness of the med that makes me feel uncomfortable. Requip never made me feel jumpy like Mirapex does. I only use Requip a few days every couple of years to boost my Zoloft's response. F 45
10/17/2009
 2  Fibromyalgia neurological twitching I made 2 attempts to try Mirapex. Both were terminated within 48 hours due to severe side effects. During the early hours of the 2nd attempt, hives, itching and rash resulted in my needing to immediately discontinue using this medication. Mirapex did seem to lessen the constant twitching. Unfortunately, the side effects made it intorerable to continue taking this medication. F 53
2/8/2005
 2  Parkinsons Horrific nightmares during the first 3-4 months (now rare, but still occur). Sleep disorder. Regardless of when I go to bed, rarely sleep beyond 0330. Am on only 1.5 mg/day. So far, don't think it's helped much. Right hand/arm/shoulder shake like a leaf in the wind when chilled or fatigued. M 66
11/1/2006
 2  For Secondary Progressive MS F 45
1.5mg 1X day
12/21/2010
Email

Patient History
 1   Took for leg cramps at night. Caused high blood pressure. The side effects listed for this drug include low blood pressure but it affected me exactly the opposite. I took this drug at night for about a week and the nightly leg cramps had stopped. Then the next few nights, when I awoke at night, I just didn't feel right. The last night, I woke in the middle of the night and thought I was having a heart attack - the pressure on my chest was very intense. I took my blood pressure and it was very high (for me). I immediately discontinued this drug and have had no further symtoms. If you are prone to high blood pressure, I would NOT recommend this drug! F 68
0.125 1X day
12/30/2010
 1  Parkinson's this medication seems to destory all emotions. There's no right/wrong. no good/bad. Nothing to cry about. M 60
1.0 1X day
3/7/2011
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Patient History
 1  RLS worked but led to compulsive shopping i would not recommend this drug to anyone, and feel that patients should be warned about these side effects when this is prescribed (i was not ) F 58
0.18 1X day
11/29/2010
Email
 1  Parkinson’s Disease The popular prescription medication Mirapex used to control tremors associated with Parkinson’s Disease and Restless Leg Syndrome by millions of Americans has been linked to linked to serious side effects including gambling addiction and other unhealthy compulsive behaviors. M 29
6/30/2006
 1  restless legs on this several yrs, Doc.s increasing the drug, and # of times he was taking it, with NO CONSERN.looking back, urine prob, falling alsleep while driving. memory, depression, ocd, shopping, gambling, 70,000. to 100, 000. gone. more if adding the shopping, paying for sex, tried to kill self, ended up in mental hosptial. was also beginning to drink, and smoke again, even with copd. horrible drug, been trying to get help from Dr.s for most of this yr. zip! began running tests with neuro dr. when he bought a gun, and tried to kill himself. this is a good, hard working, honest, loyal, husband before this and have watched him become "someone else" Possible his water retintion problems, are also all/part caused by this as, since off it and home 2 weeks, he is having no problems at all. breathing is better too. no OCD, just feeling very guilty and trying to deal with what he has done. This should be taken OFF the market. I am reporting to FDA, and going to see about legal rights Had 2 drug changes, one in Hosptital, that was not holding the RL. 2nd drug is new! Horizon ??? or something that makes me think of that. 3 nights of horrible, uncontrolable shakes, kicks, twitches of whole body. huge workout, of all muscles, sweat pouring off. fell, 2nd time. tried massages, with different things, hot bath, heatpad, cold, muscle relaxers. took 3 days and nights, before we got any sleep. then started getting better. not perfect, but good. M 69
1X AN
12/6/2012
Email
 1   Mirapex made me extremely nauseous. Took it before bed and woke up power-puking, and was sick to my stomach all day - could barely get out of bed. This was not a 24-hr. flu. I did not feel at all sick. It was from the medicine. F 54
1X day
2/21/2016
 4  RESTLESS LEG SYNDROME I BEGAN TO TAKE DOSE OF 0.25 MG SINCE 2 YEARS TILL THAT DOES NOT HELP FOR RLS SINCE MY RLS BEGAN GOT WORSE SO MY DR GAVE ME TO INCREASE TO 0.5 MG TWO DAYS AGO SO I HOPE IT HELP MY RLS BE CALM. I WISH MY PARENTS STILL ALIVE SO I CAN ASK THEM THAT IF THEIR PARENTS HAD RLS ? SINCE I HAVE IT THAT CAME FROM INHERIT. F 63 2 times
2/21/2004
 1  Parkinson's This drug causes compulsive sexual behavior. Twice it has cost me time in jail! Under un-watchward physician care and mostly from the use of this drug that was prescribed to me my my doctors. It has cost me two felony charges and 9 months in jail! It has cost me a small fortune, and my life has been nearly ruined. I can't recommend its use. Avoid it! I feel that the company has been more than negligent in not warning the public or physicians properly of its dire effects on people, especially with a high suceptability to the adverse effects of oral medications. I was prescribed this drug twice by doctors(neurologists-so called), and twice in a very short time unbeknownst to me I began behaving in compulsive sexual way hughly untypical of myself. I ended up breaking the law and spent time in jail and lost virturally all I owned! I was living in a place where there were few people whom knew me well enough to properly detect that something was very wrong and that and inept "doctoring" and the very compounded effects of a very dangerous drug, -specifically MYRAPEX- I found myself in jail and a having become so compulsive in my behavior from the side effects of this drug that I became criminal in my lifesyle and mental state of mind. This drug is dangerous. The makers of MIRAPEX owe me big time! They taken no steps to comp M 52 2 times
9/13/2008
 5  Parkinson's Disease Vivid dreams, occasional brain fog I have had Parkinson's Disease for 7 years. Including DBS, Mirapex (1 mg. 3 x day) is the first drug that has stopped the tremor and given me back a mostly "normal" life. I take it in combination with Amantadine. I was shocked to read the reports in this column. My experience has been positive. F 60 1 days
6/28/2008
  

MIRAPEX  (PRAMIPEXOLE DIHYDROCHLORIDE):  Pramipexole is used alone or with other medications to treat Parkinson's disease. It can improve your ability to move and decrease shakiness (tremor), stiffness, slowed movement, and unsteadiness. It may also decrease the number of episodes of not being able to move ("on-off syndrome"). This medication is also used to treat a certain medical condition (restless legs syndrome - RLS) that causes an unusual urge to move the legs. Symptoms usually occur at night along with uncomfortable/unpleasant feelings in the legs. This medication can decrease these symptoms and thereby improve sleep. Pramipexole is a dopamine agonist that works by helping to restore the balance of a certain natural substance (dopamine) in the brain.   FDA Approval Date: 1997-07-01 (Sources: U.S. Centers for Medicare Services, FDA)

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