MIRAPEX Reviews (PRAMIPEXOLE DIHYDROCHLORIDE)

Average Rating: 2.8 (431 Ratings)

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 EXTRAPYRAMIDAL MOVEMENT DISORDERS

 Type: Rx Drug

  

MIRAPEX  (PRAMIPEXOLE DIHYDROCHLORIDE):  Pramipexole is used alone or with other medications to treat Parkinson's disease. It can improve your ability to move and decrease shakiness (tremor), stiffness, slowed movement, and unsteadiness. It may also decrease the number of episodes of not being able to move ("on-off syndrome"). This medication is also used to treat a certain medical condition (restless legs syndrome - RLS) that causes an unusual urge to move the legs. Symptoms usually occur at night along with uncomfortable/unpleasant feelings in the legs. This medication can decrease these symptoms and thereby improve sleep. Pramipexole is a dopamine agonist that works by helping to restore the balance of a certain natural substance (dopamine) in the brain.   FDA Approval Date: 1997-07-01 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by length of time drug was taken longest to shortest.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR MIRAPEXCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  Parkinson ? I have been taking Mirapex since 2001 for Parkinson's but I think I was diagnosed wrong. I think I'm addicted to Mirapex now . My PD has not progressed, but can't seem to go off of it.I have a tremor in left hand only and toes were moving .Wish I had gotten other opinions. Fall asleep watching TV suddenly. I am taking 1mg of Mirapexs and 100 mg of Stalevo. Mirapex's made me sleepy so instesd of increasing dosage I take Stalevo (a wearing off drug) F 66 2001 years
5/24/2007
 5  RLS No side effects that are apparent to me. If I do not take mirapex exactly at the same time each night, my restless legs will begin and I am reminded how intolerable the syndrome is to my quality of life. I too, was diagnosed with RLS, before it was widely accepted by doctors. It was a neurologist who prescribed it for me and I cannot imagine what life would be like without this drug. I am concerned about compulsivensss but I honestly can say that I loved shopping as much before mirapex as I do now. F 55 15 years
1.5 MG 1X day
6/6/2010
Email
 4  Restless Leg Dullness of thinking, fatigue, increased headaches, ebay obsession for a while, eating excessively, weight gain, more vivid dreams, anti-social feelings (want to be left alone, not interact with people) I've had RLS for about 20 years. Think my father had it, too. As many of you know, back then the doctors did not know anything about RLS. About 15 years ago, my husband went to a "sleep doctor" told her about me and she prescribed Mirapex. The .25 mg pill did not do the job, so I started taking 1.5 pills. Then that was not enough. Now I am taking .50mg, but finding I have a headache every day and feel more fatigued. I am going back to the 1.5 pills. I have found I must take it about 5:30 pm everyday. The more I eat, the less the pill works. This should be a good way to diet and I must really do that. I do have vivid dreams, but I always did have dreams, even with color. However, I've noticed my dreams now are more stressful, which is another reason to go back to the lesser amount. If I am really involved in an activity and forget my pill, which I frequently do, when I take it later, it takes hours to kick in. I like to paint. I find when I have taken the mirapex, my "creativity" goes downhill. All in all though, I must learn to recognize the bad side effects and deal with them. I would have a miserable life if it were not for Mirapex. F 69 15 years
.50 1X day
8/22/2010
 1  Orig Clinical Study in 1997Park Dis SEVERE Sleep Attacks, SEVERE Impulse Control Disorders, Cellulitis from swollen ankles, SEVERE Dopamine Agonist Withdrawal Syndrome-Included suicide attempt. Restless Leg Syndrome, Inability to Sleep. Interesting to find another person who has also fallen down a flight of stairs during a sleep attack. I was not so 'lucky' After two spinal surgeries I have rods and pins in my back. I had my first car accident , plus over ten more. In the one I totaled I was told the pressure on my knees was the car engine. I've been on anti-seizure meds a year since I started DAWS Studies have shown the longer you ingest this drug the less your chances for full recovery. The Dr. who titrated me off this Hell-go-Round saved my life, what's left of it. INGESTER BEWARE! There s/b a zero rating. F 60 14 years
1.5 3X day
3/7/2012
Email
 1   RLS My husband has been on mirapex for about 12 years. He has uncontrollable actions. From fishing for hours,golfing, spending hours playing unline poker(morning, noon, night), shopping online, playing poker twice a week in our community, and now started driving 50 miles to a casino. What ever he does, he does it to the extreme and coversup and lies about the time he fill his addiction. The doctors just keep increasing his dosage. He falls asleep without warning, lies, mentally and verbally abusive, He can't just rest, he has to be filling one of his addictions. He now takes two or three 1.5 mg day. Along with 0.5 mg Clonazepam and prozac. (He just stopped the clonazepem, after a recent eppisode where he couldn't even talk.)It is distroying a 39 year marrage. HOW does he get off this terrible drug. M 57 12 years
8/13/2009
 3  RLS No real side effects for 9 or so yrs, worked well but I steadily had to have dose increased from . 25 mg daily to present 2 mg daily as RLS rolled over the meds. Now I'm sure Mirapex has augmented since RLS NOW affects one or two legs at a time, going into thighs, happens anytime day or nite, can last 20 min. or all nite (lately all nite), have more and more leg jerks and my tricks (like hot water on my legs from shower or laying down for awhile) do not work. I've, of course, developed a horrible sleep pattern of absolutely no sleep or if I'm lucky 3-4 hours per day. Becoming scared to drive, afraid of nodding off like I have when talking with people. I'm being switched to Requip but am not expecting much. My sister takes Requip for mild RLS symptoms, nothing like mine. To finish up, I hate RLS with a passion ... It steadily gets worse and control is near to impossible the longer it goes on. Unless yr doctor has had personal experience with this condition, I don't think they ge F 72 11 years
1 mg 2X day
1/19/2015
 1  rls My Husband was diagnosed around 1999 with Rls.This diagnosis was just a verbal diagnosis from Doctor Frank Chiampi with my husband explaining his symptoms to the doctor.The symptoms being the irratating feeling as his legs and feet had worms and bugs crawling through them so bad that he would be trying everything to relieve them banging them against the wall etc.My husband was immediadley perscribed Mirapex.Not long after my husband developed a compulsive gambling addiction.He has decribed this as urges so strong and would be thinking about gambling all the time .He also describes this as just gambling to gamble not for gain but to fulfill really bad urges. He has got really high amounts of money online and just gambled that away.I had once found sheets of paper with numbers written down as like as to find a pattern or something.I had to keep our bank accounts in my name after many times of online gambling .He eventually did the unthinkable and stole from his job.This record has been e M 11 years
5 mg 3X day
4/3/2012
Email
 1  Restless Leg Syndrome Severe paranoia and paranoid delusions including shooting at neighbors believed to be hurting me; compulsive behavior in terms of shopping, hoarding, eating; impulsive behavior such as acting without thinking of the consequences; lost career; was arrested for the first time for a felony in my 60s; detached retina; had pneumonia including hospitalization about 9 times; was hospitalized three times for syncope; experienced excessive sleepiness during the day and had difficulty driving and staying awake; herniated disk (L4-L5); stenosis; curved spine; problems breathing and weezing that mimicked asthma; Mirapex pretty much ruined my life over the course of 11 years and the doctor failed to recognize that the Mirapex was causing problems. The symptoms of Mirapex resulted in countless misdiagnoses of other conditions such as narcolepsy and asthma, and it did untold amounts of damage to my eyes and teeth. I had a detached retina in which I lost half of the sight in my eye; I had three tooth I believe it is criminal for doctors to prescribe a dangerous drug like Mirapex for a relatively benign condition like restless legs. The drug companies involved have made out like bandits by extending their patent to restless legs when the patent for its use with Parnkinson's was about to expire. F 61 11 years
2 MG 1X day
9/10/2013
 5  RLS None that I'm aware of - I was taking Permex previously. My Mother, Sister, and Daughter also have severe RLS and take Merapex- with no apparent side effects. It has been a "lifesaver" for us. F 68 10 years
50 mg 2X day
7/20/2011
 5  to hope it would stop aching legs Only brief nausea the first week of starting on mirapex. I have been taking mirapex for over 10 years. For me it was a life saver. With a very ill husband and maybe three hours sleep a night I was living in a sleepless daze. I was reading everything on line and in magazines when I ran across an article about mirapex helping rls. My arthritis dr. had received information from Mayo Clinic and prescribed it for me and it has helped me from day one. I never take it during the day and drive because of falling asleep side effects. So far it has helped me during the day until late in the afternoon and may have to increase to four .125mg pills instead of three .125mg in the evening two hours before bedtime. I now know I have had fibromyalgia since childhood and never had restless legs. I moved my legs because they ached not because of a creepy crawly feeling. F 79 10 years
1/4/2007
Email
 5  rls I have been taking this drug for many years and it has saved my life my legs are so bad I go crazy but with this drug I am hole sorry for the haters I have no side affects M 55 10 years
3mg
2/20/2016
Email
 5  RLS None whatsoever has been completely effective from virtually the first day M 73 10 years
2/25/2009
 4  Head injury that gave me rls I stopped mirapex for requip but had bad withdraws from mirapex body locking up like my jaw and every joint on my body hurt I have now returned to taking mirapex M 55 10 years
3 mg
10/9/2015
 4  rls/fibro The side effects stink...weight gain, urges etc. but my life isn't worth much without this drug. I don't sleep at all. I have had rls since my 20's and I just wish I had this drug back then. F 44 10 years
.25 4X day
1/5/2011
Email
 3  RLS OCD, irrational irritation, hallucinations, concentration problems, falling asleep(narcolepsy), extreme sweating with sweet vanilla scent, swollen feet with discoloration, weight gain. I increased the dosage about 2 years ago and 1.5 years ago I lost my job with a very prestigious university because of the side effects. I was not even aware of that I had side effects until I read the comments on this site. I need to get in touch with others that have taken legal actions, please email me if you are taking legal action. M 43 10 years
2.8mg 1X day
9/20/2010
Email
 3  RLS Weight gain, increased sexual desires, RAGE, falling asleep while driving, aches and pains, RAGE, obsessed with death although not suicidal, confusion, RAGE, overall addictive behavior, tremers, balance issues, pain, and did I mention RAGE. My RLS is fine though. (.75 nightly) Tried to quit cold turkey and spent two days flopping like a fish. The RLS came on like a f***ing bullet train over my entire body. However, even though I was so tired, the aches were gone. I'm back on it now and back to being a psycho. AND WHAT ARE YOU LOOKIN AT!!! Sorry, I just do that from time to time. The RLS is fine though. M 39 10 years
7/22/2009
 1  Restless leg syndrome Severe gambling addiction and shopping addiction I would not recommend this drug to anyone. It has ruined my life. I have lost everyone close to me. Since discontinuing this medication, I am no longer addicted to gambling I have suffered severely from taking this drug. Any comments from anybody else who also affected with an addiction from taking this drug or Its generic, Pramipexole, please don't hesitate to contact me. F 65 10 years
3 MG
1/4/2015
Email
 1  Restless Legs Compulsive-Impulsive spending; Hyper-sexuality; gambling; theft; reckless driving; binge drinking/drug use; legal trouble The drug is a "MIRAcle" for the condition itself, but not worth the hell you go through personally or put others through with the crazy side effects. Try Neupro the patch for RLS. F 42 10 years
1MG 2X day
4/16/2018
Email
 1  RLS My husband takes Mirapex for RLS. Excessive Gambling, Cocaine use, compulsive behavior, memory loss, Poor sleep habits My husband started taking Mirapex for RLS and at first it was a miracle drug for him. He could finally have a restful night's sleep. I strongly believe this drug is changing him in a bad way and destroying our marriage. He always enjoyed gambling, but now he spends so much money its scary. He started using cocaine over the past few years while we'd be away on vacation then started using it at home over the past year. He only admitted to the cocaine use after me questioning it for a year and finding evidence of use and threatening to leave our marriage. He says he isn't doing it anymore. I strongly believe this drug is changing him into someone else. He goes from one compulsive thing to the next. Gambling, drug use, smoking too much, drinking too much, distancing himself from family, lying. Help! I want him to go to the DR to get a full physical and to see if this drug has anything to do with the compulsive strange behavior. He doesn't even have to go to the Dr for regular physicals each year to check this med and what it's doing to him. The Dr just continues to prescribe it when prescriptions run out without any medical evaluation. I'm positive its the Mirapex that's changing him. He started on .25mg and just recently had taken 4mg to find relief and then had an episode of such a terrible headache he was in bed for 24 hours. F 40 10 years
1mg + 1X day
1/12/2012
Email
 1  Restless Leg Syndrome Highly addictive!!! Would sometimes bring on the RLS; but mostly just didn't really do much after the first couple of years. Mirapex worked great for the first year. Then it slowly lost its effectiveness. My doctor tried increasing the dosage and changing the frequency and times of day I was taking it. We tried drug holidays which worked for the first couple of times then stopped. We added other drugs and I even tried many, many non medical treatments. But the real problem is that it just really didn't work any more and when I tried to stop using it, my RLS became unbearable. I used to believe this drug was a miracle. Now I would not recommend any one starting it. Just go on the web and you will find hundreds of stories of people who can't find a way to get off it. M 64 10 years
.5 Mg 2X day
6/10/2012
Email
  

MIRAPEX  (PRAMIPEXOLE DIHYDROCHLORIDE):  Pramipexole is used alone or with other medications to treat Parkinson's disease. It can improve your ability to move and decrease shakiness (tremor), stiffness, slowed movement, and unsteadiness. It may also decrease the number of episodes of not being able to move ("on-off syndrome"). This medication is also used to treat a certain medical condition (restless legs syndrome - RLS) that causes an unusual urge to move the legs. Symptoms usually occur at night along with uncomfortable/unpleasant feelings in the legs. This medication can decrease these symptoms and thereby improve sleep. Pramipexole is a dopamine agonist that works by helping to restore the balance of a certain natural substance (dopamine) in the brain.   FDA Approval Date: 1997-07-01 (Sources: U.S. Centers for Medicare Services, FDA)

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