MIRAPEX Reviews (PRAMIPEXOLE DIHYDROCHLORIDE)

Average Rating: 2.8 (431 Ratings)

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 EXTRAPYRAMIDAL MOVEMENT DISORDERS

 Type: Rx Drug

  

MIRAPEX  (PRAMIPEXOLE DIHYDROCHLORIDE):  Pramipexole is used alone or with other medications to treat Parkinson's disease. It can improve your ability to move and decrease shakiness (tremor), stiffness, slowed movement, and unsteadiness. It may also decrease the number of episodes of not being able to move ("on-off syndrome"). This medication is also used to treat a certain medical condition (restless legs syndrome - RLS) that causes an unusual urge to move the legs. Symptoms usually occur at night along with uncomfortable/unpleasant feelings in the legs. This medication can decrease these symptoms and thereby improve sleep. Pramipexole is a dopamine agonist that works by helping to restore the balance of a certain natural substance (dopamine) in the brain.   FDA Approval Date: 1997-07-01 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Satisfaction highest to lowest.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR MIRAPEXCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Restless legs and muscle spasm Slight nausea for 1st few weeks This has made a huge difference too my quality of life. Night time restlessness and jerking spasms of arms legs and sometime whole body sometimes quite violent . Within a day of starting these decreased and after gradually increasing dose are Gone completely. M 72 2 days
0.75mg 1X day
7/16/2022
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 5  Rls Sudden onset of extreme drowsiness. I have fallen asleep in mid -sentence. Obsession with sex. Issues with erectile dysfunction. 67 2 years
2 50mg per 2X day
6/28/2021
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 5  Treatment-resistant depression At first I experienced tingling/ticklish sensations throughout my body along with feeling lightheaded. I had orthostatic hypotension also and some mild headaches and ringing in the ears. To counter this I got up slowly and increased my sodium and fluid intake. I also take cetirizine (Zyrtec) if I experience nausea and this resolves it. The side effects dissipated after a few days and increased the dosage very slowly over the next few weeks. My depression and anhedonia went into remission and I finally have my life back again. I'm currently taking 0.25mg t.i.d. I don't understand why some people experienced obsessions or compulsions because I haven't. I just feel normal and very emotionally stable now. Pramipexole is now being used by some psychiatrists for treatment-resistant depression. M 48 27 days
0.25mg
6/10/2020
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 5  RLS Low bp 90/60 and high heart rate of 120.can not say if these side effects are due to mirapex. Since last 5 days when i started taking mirapex i feel i got anew lease of life. My life had become miserable. I was in constant pain and sleepless since last 4 years. The medication that doctors tried on me during last 4years were 1. amitriptyline 0. 5mg 2. chlordiazepoxide 0.5mg 3. gabapentin 625mg 4. pramipexole 1mg I found mirapex as a wonder drug. Can not say if the low bp and high heart rate is due to mirapex or these are the withdrawal symptoms of the drugs that i have taking all these years. Presently i fell as if i never had rls. Mirapex has helped me to that extent. How long it will work only god can tell. M 68 5 days
0. 25 mg
8/21/2016
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 5  Restless leg syndrome. Headaches sometimes. I am so greatful for Mirapex! It has made such a difference in my life. F 57 3 years
.25 mg
3/20/2016
 5  rls I have been taking this drug for many years and it has saved my life my legs are so bad I go crazy but with this drug I am hole sorry for the haters I have no side affects M 55 10 years
3mg
2/20/2016
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 5  for rls Requip gave me severe nausea. I have had no side effects from Mirapex. F 60 1 months
o.50 mg
8/30/2015
 5  rls Weight gain, memory loss, confusion, insomnia, anxiety, twisting and tightening of my muscles compulsively. In the first few yrs of taking mirapex, i was taking low dose and only when i needed it. Of course the rls beast continued to grow and i now cant go a day without mirapex. But now that i take it constantly and at much higher dosage, i am experiencing crazy side effects. Rls is a living hell, it really is. I have experimented with a few other meds like requip and they did nothing. Im terrified because the beadt is out doing the mirapex and my body is not handling the increase well. But the thought of having nothing to ease the hell is something i cannot even fathom. What am i supposed to do? F 50 5 years
1mg daily
1/24/2015
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 5  RLS Originally it made me somewhat nauseous and dopey. I stopped it, went back on Requip, quit that, and tried Mirapex again. Never had a problem after that. I was originally prescribed Requip for RLS, but found that it stopped working after a relatively brief period of time. Switched over to Mirapex and never looked back. Works like a charm. An added benefit is that is makes me drowsy. I take before bed so that's perfect. F 58 5 years
.50 1X day
12/21/2014
 5  rls I have bad compulsive disorder for gambling. I need to change mirapex to something that wont cause complusiveness.but it must work for my rls thank you 69 1 days
60 mg day
11/7/2014
 5   After 40 yrs on all types of medication for depression mirapex has finally helped me with my depression. Only side effects are swollen ankles and stiff lower legs ( arthritis like) to the point that I have trouble moving after being in any sitting position and begin to walk. When walking notice some stumbling and stiffness in writing. M 68 3 months
.25 MG 1X day
10/10/2014
 5  RLS I had RLS so bad. My Dr prescribed Mirapex, 0.25 at first and now I'm taking 0.50 every night. I'm really amazed that Mirapex has helped me this much. I have not had any symptoms of RLS since day one. I have had no side effects. I've actually lost almost 30 pounds in 4 months. F 42 4 months
0.50
12/13/2013
 5  MS induced RLS I am not aware of any side effects. Very surprized reading all the bad reactions - I guess I am VERY lucky. Mirapex has been a godsend for me. I don't think I could function without it. Started 5 yrs ago taking as needed but now increased to daily. Of all the meds I take, I think Mirapex would be the last one I would give up. F 60 5 years
0.50 mg 1X day
11/13/2012
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 5  RLS Possible memory impairment. I don't care. Mirapex is a miracle for me. No obsessive/compulsive behaviors, narcolepsy, nausea, etc. I can SLEEP! My RLS is so awful that my legs jump by themselves if I don't move them proactively. It's unbearable torture. I'd rather be in pain. Thank you Mirapex! F 51 1 years
0.25 mg x2 1X day
4/29/2012
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 5  RLS Initially some drowsiness. Some obsession with a particular relationship and increased sex drive while taking bioidentical hormones also, for first two years. Recently some fibro type stuff. But all these could have other explanations or have appeared anyway. Overall a life saver the last five years. Previously had RLS for 35 years, had gotten to be nightly two hour sessions. I started on half a min. dose: .125 mg once a day at dusk, and that worked (unless I forgot) for 4 years. Then, along with some stressful life events, RLS would break through some and I increased it to .2 mg. Now I think I better up it some more, a year later. F 61 5 years
.125 mg 1X day
8/17/2011
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 5  RLS None that I'm aware of - I was taking Permex previously. My Mother, Sister, and Daughter also have severe RLS and take Merapex- with no apparent side effects. It has been a "lifesaver" for us. F 68 10 years
50 mg 2X day
7/20/2011
 5  RLS This drug has saved my life. I could not sleep without it. I have had no side effects from taking Mirapex. I have had no side effects at all with Mirapex. It truly has been a "Miracle" pill for me. I have been taking it for 2 years. F 64 2 years
0.5 1X day
5/28/2011
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 5  Restless Leg Syndrome slight morning headache at first; none now drowsiness This drug was an excellent fit for my situation. The sleep study results indicated 'involuntary periodic limb movements' and I exhibited the symptoms of RLS over the years. My sleep was disrupted and not restful. Now, I sleep through the night and am very comfortable. I take one .5 about three hours before bed. It is possible that .75 might be needed when I go in for my 90 day follow-up with my primary care physician-I still have some symptoms during the afternoon but counter that by doing some physical labor--weed, clean the pool, vacuum. I have a lot of energy! F 56 2 months
.5 mg 1X day
2/14/2011
 5  RLS Minimal side effects. Nasal congestion 30 minutes after daily dose. Poor sleep habits, frequently awake at night, drowsy while driving. To be fair, have had sleep issues since onset of RLS and could never stay awake while in a car. Mirapex could be your miracle drug. I spent 10 years in pain and insomnia before RLS was diagnosed 8 years ago. Without Mirapex I would be a basket case. Based on what I read here you will want to proceed with caution. M 54 5 years
2mg 1X day
1/18/2011
 5  treatment resistant depression none went off of Mirapex for just a few days (to try a different yet conflicting med), extreme suicidal thoughts and was ready to self-admitt to be hospitalized. Went back on, was fine. F 33 2 years
0.75 3X day
11/10/2010
  

MIRAPEX  (PRAMIPEXOLE DIHYDROCHLORIDE):  Pramipexole is used alone or with other medications to treat Parkinson's disease. It can improve your ability to move and decrease shakiness (tremor), stiffness, slowed movement, and unsteadiness. It may also decrease the number of episodes of not being able to move ("on-off syndrome"). This medication is also used to treat a certain medical condition (restless legs syndrome - RLS) that causes an unusual urge to move the legs. Symptoms usually occur at night along with uncomfortable/unpleasant feelings in the legs. This medication can decrease these symptoms and thereby improve sleep. Pramipexole is a dopamine agonist that works by helping to restore the balance of a certain natural substance (dopamine) in the brain.   FDA Approval Date: 1997-07-01 (Sources: U.S. Centers for Medicare Services, FDA)

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