SEROQUEL Reviews (QUETIAPINE FUMARATE)

Average Rating: 2.9 (1505 Ratings)

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 ANTIPSYCHOTICS ANTIMANICS

 Type: Rx Drug

  

SEROQUEL  (QUETIAPINE FUMARATE):  This medication is used to treat certain mental/mood conditions (such as schizophrenia, bipolar disorder, sudden episodes of mania or depression associated with bipolar disorder). Quetiapine is known as an anti-psychotic drug (atypical type). It works by helping to restore the balance of certain natural substances (neurotransmitters) in the brain. This medication can decrease hallucinations and improve your concentration. It helps you to think more clearly and positively about yourself, feel less nervous, and take a more active part in everyday life. It may also improve your mood, sleep, appetite, and energy level. Quetiapine can help prevent severe mood swings or decrease how often mood swings occur.   FDA Approval Date: 2005-10-04 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by length of time drug was taken from shortest to longest duration (reviews with no time reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on SEROQUEL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR SEROQUELCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  Bipolar NOS - psychosis - anxiety Currently I am on 400mg daily (split doses 3 times a day). No sleepiness, fatigue, or lethargy as others report unless more than 250 mg are taken at 1 time. So far I've noticed that I crave sugary foods, although I do not eat much at all anymore. Actually losing weight (probably because I eat sugar-free candies instead of the sugar I crave). No more roaring in my ears, weird out of body experiences, and my mind doesn't play tricks on me so much. I actually like this med ALOT. When I feel myself talking way too wicked fast, and very confused in my own head, and hearing/seeing things, I know my next dose is due. Kicks in about 25 minutes later and I feel serene - a rare feeling for me. F 26 14 days
3/17/2007
 4  lamictal drug induced psychosis rapid heart beat, sedation lamictal gave me a psychosis, that means drug induced psychosis, what helped so far is abilify and seroquel. i am currently taking 100 mg twice a day for this condition, i will talk with my doc to increase to 200 mg, it has helped me but it has side effects M 14 days
2/23/2008
 3  Bipolar 1 It relieved the teeth clenching and tight neck muscles that I've had, mainly from Lexapro, for several years. Dry mouth (in addition to dry mouth that I already had from Lamictal). I'm just starting Seroquel, some of the side effects might go away. I do feel a little stoned an hour or two after taking 200 mgs or more. Then of course there's the sleep-inducing effects, which I find excellent at bedtime. Hasn't been a problem during the day at all. I think I'm more awake and productive during the day now than before. I was diagnosed with a sleep disorder (nonspecific hypersomnia) years ago. I've got my fingers crossed, hoping that Seroquel might be the perfect marachino cherry atop my cocktail of Lithium (20 years), Lamictal, Wellbutrin XL and Lexapro. M 14 days
5/13/2006
 3   Groggy, grumpy, cranky. I took it for anxiety and sleep problems. It help's a tiny bit, but then after a couple days I was too cranky and moody to continue medication. Felt like I drank cheap wine the next day, kinda like Trazadone. M 47 14 days
50 MG 2X day
2/2/2015
 2  sleep weight gain, increased hunger and skin rashes It did help for falling asleep sometimes but it keeps causing purple scaly rashes on me so I had to stop taking it. I took it for about three days recently and developed scaly cracking bleeding knuckles on my hands. It hurts and my hands feel like sandpaper. I have been taking it off and on for about three months and also have gained I think roughly 10 lbs. If you stop taking it some of the water weight will come off if it causes that for you. If you are of asian genetics or native american please do not take this. I am half native american, so I think that's why my skin is having problems. It's kind of scary. I hope it heals. F 32 14 days
25 MG 1X day
12/8/2020
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 2  Schizophrenia Seroquel caused me to have a rapid heartbeat, uncontrollable shaking of the hands, memory and coordination problems, confusion and loss of awareness. I ended up in a Mental Hospital for two weeks because of this drug. I started on 600mg at night and then Psychiatrist increased to 800mg. I could not think clearly, it affected my memory, I experienced acute confusion which resulted in me not being aware of where I was. I felt like I had lost control of my mind, a truly frightening experience. It had no effect on the paranoid delusions I was suffering from, it made me suicidal and all these symptoms continued for weeks after stopping the drug. Eventually these horrible side effects subsided, and I am now stable on Zyprexa (Olanzapine). This drug may work for some people, but for me it was a living nightmare. M 28 14 days
800mg 1X day
3/21/2011
 2  Insomnia and bipolar Dry Mouth, clumsiness,grogginess. I couldnt get out of bed in the morning and getting up with my kids at night was almost impossible. I couldnt hear them because I was so knocked out. F 31 14 days
8/8/2006
 1  cronic insomnia Worst hangover I have EVER felt from any sleep medication, and I was only taking 25mgs. Even at such a low dose, it was miserable. Sure I fell asleep - out cold, unconscious within a half an hour of taking the medication. But i could never wake up, even 10-12 hours later, groggy all the next day, felt like my head was in a cloud, and I have no recollection of most of my mornings. I stopped taking it after a few weeks because I couldn't handle the side effects. oh yeah, weight gain like crazy!! F 20 14 days
2/12/2007
 1  Mania extreme dizziness; unsteady balance; extremely dry mouth; painful constipation; excruciating headache on left side of head; extreme thirst It has terrible side effects. I stopped taking it after 2 weeks because I thought my brains were going to explode out of the left side of my head. F 51 14 days
4/11/2009
 1  Depression, anxiety Sleeplessness and EXTREME anxiety I was put on Seroquel after a death in my family. I had been on Paxil for years and I absolutely loved that drug, but it started to give me anxiety attacks and I weened off. I tried a whole mess of medications afterwards, but Seroquel is the one that caused me the most dissatisfaction. I was up all night for days.. my heart was racing and my anxiety was 10x what it usually is. It is amazing for me to read that so many people got sleepy with this medication because it has the opposite effect on me. I guess it is true that brain chemistry and the drugs it responds varies drastically. F 14 days
9/12/2009
 3  heroin withdrawal blessed sleep, unconsciousness during withdrawals. I've cold turkey detoxed off heroin and oxycodone many times. This time I had a large heroin IV habit. I was prescribed soroquel 25 mg. twice a day for relief from withdrawal effects. It allowed me to sleep for most of the first three days (the worst of the withdrawals). The only problem is, luckily I had family attending me 24/7 because I was so out of it, I vomited while lying on my back and unconscious. I would have choked to death without their help. Not to mention falling while trying to make it to bathroom. M 55 15 days
9/23/2009
 1  Bipolar disorder Horrible. I have tried lamictal and abilify. I am 61 years old, had OCD since age 12. Have been taking Prozac with complete success for 25 years. Started crying or feeling eurphoric. All of these meds have made me feel like I am no longer me and I hate it. Seroquel does make me sleep great but I'd rather cry all the time and feel like me than this other person. I feel like I am becoming unconscious. I'm off of these now, too, effective tonight. I believe this is my third bipolar episode. Had one 10 years ago. I started taking 2 Prozac instead of only one and it happened. This time my psychiatrist told me to take 2 again for the depression and constant crying, I told him I couldn't and he told me to do it anyway. Big mistake. Prozac is my "get out of jail free" card, and I won't do without it but the seroquel is horrible for me. I only took 25mg last night. I was perscribed 100mg, then he decreased it to 75. I decreased it to 50, then 25, and now zero. Makes me feel unlike myself. F 61 15 days
1/1/2009
 3  manic depression and aniexty,sleep weight gain...cant not stop the weight gain,sleepy, I first wrote on this site a few months ago but know Iam back because my doc thought it was a good idea to cut my meds in hald so he ahd me take 200 mg instead of 400mg but once I cut it in half I couldnt sleep and I was real cranky and had aniexty attacks I couldnt stop, so I toold him we needed to go back to 400mgs I just need to know if anyone else is having a hard time with the weight gain ? He wanted me to switch to somehting else similar to Seroquel that wont make me gain weight I'm just not sure if I should switch or not cause you never know if the new meds will do better or not.Ive been taking Seroquel since june of 07 it made my mood great and aniexty go away and I slept good,,, F 30 16 days
3/27/2008
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 5  Mayjor depression bipolar schiz Ins First time i took em i liked it. Made me feel dizy like i was high. sex drive is down. i as well noticed that it dont have much energy. But i tend to get up and take a jog. Thats why people are getting fat off it.. Because they sleep to much on it. Im 174 and i tend to keep it low. My depression and mood swings are finnaly going away. At times i feel there not working so i think imma get a higher dose. There good... i really like them. Just a reminder, if you dont want to gain weight just get up and go for a walk/jog. dont be such a bum. I love to help people, as well helps me with my problems. ok im a bit drugged now M 18 20 days
3/28/2007
 4  Depression and anxiety Dry mouth and daytime sedation. I have chronic depression and anxiety and, over the years, was prescribed the more common SSRIs, SNRIs, and NDRIs with little to no effect on symptomatology. After beginning Seroquel initially for irritability, anxiety, and insomnia, I noticed improvement in as little as one week. I am approaching my 3rd week on Seroquel and, aside from daytime sleepiness and dry mouth, I am quite satisfied. I have noticed an overall improvement in my mood, ruminative/obsessive thinking, anxiety, irritability, and sleep. M 44 20 days
100 MG 1X day
4/11/2011
Email
 3  Anxiety & Depression The worst thing is the tiredness. I was almost passing out the first few days. I also had dry mouth. I noticed that after a few weeks that my sexual libido went way up. It also makes sex more pleasurable for me. I also noticed that my food tastes better to me and my appetite is way up. That's not a good thing. M 39 20 days
50 2X day
3/22/2011
 3  bi polar II and depression get sleepy within an hour of taking it, but can stay up if i want. headaches at first, but they have subsided after about a week. so far so good...it is seeming to help with mood, focus, regular sleep pattern, depression etc. i am concerned about its long term usage and plan on talking to my dr about it. i don't get the over eating problem that i am reading in many of the comments...my appetite has remained normal. i'm curious to see how i feel in another month of taking it. but as of now, i am starting to feel much better with each day that i'm on it. i rarely get side effects from RX drugs...dunno why. M 27 20 days
2/22/2009
 2  sleep issues Excema break-outs on my scalp worsened and began on my face (not cool); nightmares, tiredness in the day, forgetfulness and an inability to think properly (not good when trying to write papers for school); MUCH worsened parathesias in my left arm (already had these infrequently due to ulnar nerve damage; now they are much worse and my entire arm is constantly "buzzing"); think it is preventing weight loss; crazy-ass nightmares - vivid and disturbing 25 mg/night; I am going off of it, I've only been on about 2-3 weeks, switching back to melatonin; my Dr. gave me this to help me sleep, but after just a few weeks the side effects are just way too crappy - it does help me sleep, but I have a horrid time getting up and feel totally out-of-it and dull; plus the nightmares are just creepy; I am really not liking the excema that has broken out of my FACE - I am sure this drug is great for some PPL, but it definitely does not agree with me F 36 20 days
12/6/2007
 5  depression, anxiety sleepy F 59 21 days
5/28/2008
Email
 4  Imsomia I am concerned about the blood sugar rise possibility of other serious side effects. This is definitely the most potent sleep med I have taken (though it is NOT FDA approved for sleep) I would like to get off of it but have to say my sleep suffers without it. My problem with sleep is that I wake throughout the evening. Seroquel does not solve this but it does make it easy to fall back asleep. Its very hard to get out of bed when taking this medication. I am going to explore other options including a new drug that targets the sleep / wake cycle, and its approved for long term use. My true advice is to use this med with extreme caution and stop it if possible, depending on your condition. M 42 21 days
3/3/2009

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