SEROQUEL Reviews (QUETIAPINE FUMARATE)

Average Rating: 2.9 (1505 Ratings)

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 ANTIPSYCHOTICS ANTIMANICS

 Type: Rx Drug

  

SEROQUEL  (QUETIAPINE FUMARATE):  This medication is used to treat certain mental/mood conditions (such as schizophrenia, bipolar disorder, sudden episodes of mania or depression associated with bipolar disorder). Quetiapine is known as an anti-psychotic drug (atypical type). It works by helping to restore the balance of certain natural substances (neurotransmitters) in the brain. This medication can decrease hallucinations and improve your concentration. It helps you to think more clearly and positively about yourself, feel less nervous, and take a more active part in everyday life. It may also improve your mood, sleep, appetite, and energy level. Quetiapine can help prevent severe mood swings or decrease how often mood swings occur.   FDA Approval Date: 2005-10-04 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on SEROQUEL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR SEROQUELCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  Schizophrenia 1. Ridiculous sedation - I slept between 14-18 hours per day every day on the drug. It never got better. In fact, it simply got worse. 2. Cognitive sluggishness - this is easily the worst antipsychotic for ruining the intellect. I could not comprehend subject material that I used to find extremely basic. It was embarrassing to be honest. Yes. The side-effects were bad, but not the worst of any drug I have been on. However, the true problem was the the drug was ineffective for my Positive Symptoms. 300 mg is not that high of a dose (the max dose I took), but I simply could not bear to go any higher because I was sleeping 16 or more hours per day. It was totally ridiculous. I was still having strong psychotic breaks and all I was getting from the medication was sedation. M 25 10 months
300 1X day
3/25/2013
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 2  Bipolar I Pisa Syndrome(please google) *weight gain* Seroquel is a very effective drug for me. I am now getting off Seroquel. It's the weight gain thing. If your genes are set up for you to gain weight on this, you will, probably very quickly. I've had enough and I usually put up with most side effects. At 60, putting on 40 pounds is dangerous. Really at any age. Hopefully Lithium and Lamictal will keep me afloat because I'm not gaining another pound on this. M 60 2 years
300 mg 1X day
4/1/2013
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 2  sleep No side-effects. Withdrawal causes problems. Switch to zyprexa 20mg and cold turkey it. Alternatively increase seroquel to 600mg and stop it but doses above 400mg make seroquel work like mild SNRI and are not long-term. Never start antipsychotics voluntarily. Always use neurologists and sleeping pills. M 32 2 years
400 1X day
5/16/2013
 2  schizophrenia grogginess, flat mood, irritability, unmotivated, hopeless It's maybe good as temporary relief from psychosis but nobody should try to build a life around this..it will be a shitty empty life I promise you. M 41 4 years
75 1X day
1/4/2012
 2  Schizophrenia Seroquel caused me to have a rapid heartbeat, uncontrollable shaking of the hands, memory and coordination problems, confusion and loss of awareness. I ended up in a Mental Hospital for two weeks because of this drug. I started on 600mg at night and then Psychiatrist increased to 800mg. I could not think clearly, it affected my memory, I experienced acute confusion which resulted in me not being aware of where I was. I felt like I had lost control of my mind, a truly frightening experience. It had no effect on the paranoid delusions I was suffering from, it made me suicidal and all these symptoms continued for weeks after stopping the drug. Eventually these horrible side effects subsided, and I am now stable on Zyprexa (Olanzapine). This drug may work for some people, but for me it was a living nightmare. M 28 14 days
800mg 1X day
3/21/2011
 2  Bipolar type II Nightmares, anxiety, short term memory loss, decrease in appetite, stuttering, passive-aggressive behavior, uncontrollable eye movements, trouble concentrating, From taking this drug I got nothing but waking up in the middle of the night sweating from nightmares. I also lost my ability to communicate and express how I felt which made things worse with the friendships I had with people, which eventually destroyed those relationships and made me more depressed. I now know how people feel when they say these drugs turn you into zombies. I have vowed to never again take this drug ever again to let big pharma get a hold of my life. I have never been more lonely than I have been after taking this drug, I started to develop mild schizophrenia during and after it; not to mention severe withdrawal and "brain zaps". Do yourself a favor and stay away from this drug, oh by the way I use to like smoking bud from time to time but I can't even do that now because it worsens my anxiety and panic attacks. I think the worst part was not being able to just be myself, I felt as if I was desperate most of the time when at social functions and the uncontrollable eye movement only made things worse with the opposite sex. F* Seroquel. M 23 1 months
25mg 2X day
6/23/2010
 2  depression/anxiety and sleep While taking I was like a zombie. Hard to get anything done. Loss of appetite. I was pretty much out of it for the entire day. Withdrawal horrific muscle fatigue mainly mid back and arms were tired and limp, stomach cramps memory loss can not remember a thing as of 3 days off of it. For me I did not like this medication did not help me with what it was prescribed for. I fear long term damage of my muscles and my eyes. M 39 4 weeks
150-50xr 1X day
7/8/2010
 2  Bipolar - paranoia/anxiety No motivation, lack of concentration/focus, feeling stupid, occasional seroquel hangover/difficulty getting out of bed in the morning I have had an on again off again relationship with this med over a number of years I have previously taken daily doses as high as 200mg but that turned me into a zombie. I don't think seroquel agrees with me even on 25mg a day I still get the side effects I listed. No where near as severe as when I was taking 200mg but it still messes with my cognitive functioning. That having been said given my previous experiences with other anti psychotics seroquel's side effects are mild. I'm going to stop taking it though I can't keep up with my peers seroquel is making me look an idiot. M 32 3 months
25 1X day
8/27/2010
 1  Insomnia Went from about 130 to 200 pounds in about.. 4 months. Worst medication possible for sleeping, it helped me sleep sure. I had realistic dreams of killing people, nightmares, I'd eat 3 meals a day which several servings, I stopped dreaming after I stopped taking it for almost a year, I don't care for life anymore, anti-social, feeling as if you can't relate to anyone. Zombie/sluggish to the point where you're an observer of life as it passes by each day. This shit's horrible, I strongly suggest you stop taking it, or any other medication. There's a reason most of them CAUSE suicidal thoughts, help sleeping or whatever they intend to help, but in the end come back to bite you in the ass with their side effects, some short and others long that cripple your life, socially/personally/ and mentally. I use to love life, now I can't get motivated to do anything. You could put a gun to my head and threaten me, I'd take the bullet. M 18 8 months
250 1X day
8/30/2010
 1  Anxiety/ Sleeplessness sensitivity to heat, especially in the sun, easily fatigued after doing small work, lightheaded, dizziness, loss of focus/concentration... I work in an office 8-5 mon-fri, then go to work as a logsplitter for a fire wood business on nights and weekends. It's a strenuous job but I've been doing it for years, and never had fatigue problems like this. I started Seroquel for sleep and anxiety when it was still cold and overcast outside. Around mid-April, when it started to get hot, my muscles would fatigue seemingly out of nowhere when I was outside, muscles I wasn't even using. My body temp spikes out of nowhere. The rest of the time I cant concentrate, and it's a strain to do anything. I've taken it, fallen asleep, then bolted upright in bed like someone had shocked me. There are other effects, but I'll stop there. Bottom line, I wouldn't recommend this med to anyone. Yikes. M 28 8 months
100 1X day
8/22/2010
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 1  anxiety, stress, some insomnia No many side-effects during use. After withdrawal I CANNOT sleep and this causes major mental health problems. Seroquel had either changed my sleep architecture or permanently damaged my serotonin receptors/systems. Using doses (<200mg/day) seem to cause brain damage/insomnia as well as using only a high single dose per day (instant release). Taking BCAA supplements before bedtime (after discontinuation) seem to help with insomnia symptoms (BCAA reduces dopamine and serotonin). M 29 3 years
400 1X day
7/19/2010
 1  Sleep/mania If I take more than 200 mg, I will fall a sleep fast, but will wake up an hour later with a racing heart. Sometimes, I have to get dressed and run around the block a couple of times. In six years my weight has gone from 145lbs to 206lbs. Currently, I weigh 188. I work in a laboratory. I have noticed that my fasting blood sugars have been creeping up a little higher than I like. For the last several months, I have been very manic, and filled with anxiety. I am taking myself off this drug. In the beginning, Seroquel mad me sleep like a baby.The first night I took it, I fell a sleep on my dinner plate. I have been thinking of quitting seroquel for the last couple of years. I have not been sleeping for the last two years, so the medication is no longer working for the reason it was prescribed. Tonight, I'm going to cut my dose from 200mg to 150mg. I will do this for a week. Then, I will cut my dose to 100mg for a week, and so on until I am off the med in four weeks. M 44 6 years
200 mg 1X day
8/8/2010
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 1  Bi-polar I now have diabetes, with high blood sugar, no family history. I was not told of the increase BS issues and the questions surrounding this med, otherwise I would have never taken it. That said, It did a good job getting me to sleep at night. Don't know if it's helped anything else though. M 33 2 years
50 1X day
8/9/2010
 1  For sleep and to calm behavior Trembling, shaking, rigid arms, muscles constantly moving in calves, weakness in muscles, difficulty walking, body jerks My husband was being treated by dr. for dementia, unable to sleep, wandering at night, so was given Seroquel to help him sleep and calm his behavior. He immediately began sleeping at least 10 hours, wetting the bed because he didn't wake up. Then he was in a zombie-like daze most of the time, stopped knowing or being aware of what was going on. Staring spells. After 6 months, he began having "body jerks" where he would be sitting holding a cup of coffee and involuntarily threw the coffee everywhere. I spoke to the dr. who asked if I wanted him to sleep or have these jerking spells, he seemed to get angry that I was questioning the use of Seroquel. 3 months later, my husband began taking little bitty steps, having to be assisted, 3 months ago, he began shaking as if he were shivering, he would shake the whole bed. Two weeks ago his neurologist (who prescribed Seroquel) saw him for a routine visit and was shocked at how he had deteriorated and said IT WAS THE SEROQUEL! DUH! He said it could cause rigidity and trembling. He advised me to cut back the dosage to 25 mg once every other day. Guess what! I stopped it. After 3 days the shaking stopped, but he still has the muscle movement in his legs and difficulty walking, not quite as bad, but it's still there. My advice: Don't take this crap, it can affect you in ways you never dreamed of, maybe long term, I will have to wait and see. This stuff is as lethal as rat poison. M 67 1 years
50 mg 1X day
3/14/2010
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 1  bipolar Extreme hallucinations, lethargy, drowsiness, increased appetite I spent all of my days on the drug lethargic without any energy. My appetite dramatically increased causing me to gain unwanted weight. I had to sleep an extra 2 hours per day. The hallucinations were so extreme, I had to stop taking the drug immediately. M 18 30 days
1X day
2/5/2010
 1  to help me sleep i was taking serequel 50 mg and the 200 at night that is until my insurance stop paying for it, and now i was forced to start taking the xr, at the time i asked my doctor to wean me off, but she just lowered my dose and hasn't lowered it again since. my problem with it is the tiredness, the stomach problems, and the weight i'm always very hungry after taking it, i wake up in the middle of the night looking for food. so i'm going to talk to my doctor and see if they can wean me off and put me on ambien temporarily, the stomach pain is bad. and not getting any sleep without it is not an option M 34 5 years
150 1X day
5/21/2010
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 1  depression Bad, likely permanent damage to abdomen/colon/digestion. Can no longer eat a large variety of foods. Weight loss, extremely low mood, suicidal ideation Began at 25mg as an addition to Cymbalta. No effect on mood; upped to 50mg. Great for mood, but immediate, severe bloating/hardening of abdomen esp ascending colon. Dropped to 25mg with immediate cessation of abdominal symptoms. A few weeks later, asked my doctor if I could return to 50mg, as I really appreciated the cognitive boost of 50mg. I knew the bloating would return but felt I might be able to control it perhaps by managing diet; otherwise go off the drug completely. Bloating came back immediately at 50mg, was unable to control it, so tapered down to 0mg as per doctor's instructions. However, this time the bloating, rock-hard feeling in my colon did not go away and has been with me for 8 months. Symptoms vary in severity depending on what I eat. There is huge swath of foods I can no longer consume. This, plus the shoulder-shrugging, "there's no one who will help you with this" has led to bad depression and serious consideration of comitting suicide. I will be seeing a gastroenterologist soon, but I'd essentially been ignored until I got very angry with my doctor. M 47
50mg 1X day
2/19/2011
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 1  Paranoid Schizophrenia Seroquel caused me acute psychosis, visions and voices. It caused what it was supposed to heal. Affected the dopamine-center so that it caused the effects of early tardive dyskinesia in an age of 24. Trouble urinating. Blunt/drugged down feeling through out the day. Not a recommended medicine. Stay away if you can. WARNING: Causes severe blunt/drugged down feeling, tardive dyskinesia and Parkinsonism. M 24 1 months
350 1X day
2/28/2011
 1   They just told Bai Ling on Celebrity Rehab that Seroquel is non-addicting! Perhaps some of you might like to email Dr. Drew and tell him otherwise! I'm fed up with the medical community hiding and lying about drug side effects! M 31
1X day
7/11/2011
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 1  Bipolar ii rapid cycling constant "drugged" feeling; pressurised headache; nasal congestion; mental dullness; blurred vision; vertigo; sweet cravings; dry mouth; muscle weakness; apathy. Out of all of the medications that I have been prescribed I can honestly say that no others have been quite so debilitating in their side effects. I'd even take the akathesia of typical antipsychotics over the sheer weight of sedation I have with Seroquel. I'm sure it works wonderfully for some people. Unfortunately for me I've had to put off returning to work because of it. M 29 10 weeks
300mg 1X day
1/17/2011

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