SEROQUEL Reviews (QUETIAPINE FUMARATE)

Average Rating: 2.9 (1505 Ratings)

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 ANTIPSYCHOTICS ANTIMANICS

 Type: Rx Drug

  

SEROQUEL  (QUETIAPINE FUMARATE):  This medication is used to treat certain mental/mood conditions (such as schizophrenia, bipolar disorder, sudden episodes of mania or depression associated with bipolar disorder). Quetiapine is known as an anti-psychotic drug (atypical type). It works by helping to restore the balance of certain natural substances (neurotransmitters) in the brain. This medication can decrease hallucinations and improve your concentration. It helps you to think more clearly and positively about yourself, feel less nervous, and take a more active part in everyday life. It may also improve your mood, sleep, appetite, and energy level. Quetiapine can help prevent severe mood swings or decrease how often mood swings occur.   FDA Approval Date: 2005-10-04 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on SEROQUEL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR SEROQUELCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  Bipolar Disorder for Mania Weight gain, sleeping too much, bad dreams I have been prescribed Seroquel for about two years. The plus of this medication is that it is the only anti-psychotic I have taken that doesn't give me a serious physical reaction. Another good thing about this medication is that it made it possible for me to quit taking anti-anxiety medication. It is a sleepy enough medication to take care of any anxiety as well. It can actually take care of mania too. But, I want to quit because the dreams I have on this medication are pretty bad. They are extremely vivid. At first, I got kind of a kick out of how real the dreams were but now they become bad nightmares at times. My psychiatrist has suggested that maybe it is becoming a little to concentrated in my system, so I break the pill into a smaller piece and that seems to help. My problem is that if I try to stop taking it, even after staggering it into smaller doses for awhile, I can't quit it. I can't sleep if I try to make it through the night without it. I hate it now, because sometimes I can't wake up on time, and my other doctors keep warning me that it could cause diabetes and I have a bad family history of diabetes. But, I can't quit, it keeps me from Mania and my doctor is against me quitting. Think twice if you can stay away from this medication. F 41 2 years
150 mg. 1X day
7/14/2010
 2  depression/anxiety and sleep While taking I was like a zombie. Hard to get anything done. Loss of appetite. I was pretty much out of it for the entire day. Withdrawal horrific muscle fatigue mainly mid back and arms were tired and limp, stomach cramps memory loss can not remember a thing as of 3 days off of it. For me I did not like this medication did not help me with what it was prescribed for. I fear long term damage of my muscles and my eyes. M 39 4 weeks
150-50xr 1X day
7/8/2010
 3  Bipolar Disorder Massive weight gain, possibly addictive? Far too sedating too quickly. I am currently being weaned off Seroquel. My dose over five years has ranged from 50mg twice daily to 500mg a day. It hasn't really worked for my mania or anxiety, but I do now get a decent night's sleep for the first time in my life. However, as my Psych Doc pointed out, sleeping tablets would do the same thing so I'm being taken off it. I gained five stone (70 lbs) on this stuff, but have gotten that off now and am being placed on Lamictal. What pains me is that I knew it wasn't working for me for five years and told the doctors this and they argued with me until last year, when suddenly the reports about Seroquel started to filter through and they realised that we, the patients, were right. I accept that for some people it's wonderful and like all meds, it's a lottery as to which works for each of us, but the doctors need to listen when we say something isn't doing the job. We inhabit our skulls, and we know when something is amiss. F 36 5 years
250mg 1X day
7/4/2010
 5  Bipolar Depression/Sleep It causes my nose and sinuses to close up tighter than a drum, sometimes creating an alarming sensation of choking or suffocating. I think it also causes swelling of the prostate, making it difficult to pee when you want to. I generally have been pleased with SEROQUEL. Starting in my middle-age, I have been plagued with insomnia... racing thoughts very much a part of that. I had tried "baby" sleep aids like RESTORIL and AMBIEN, but they were just pi$$-in-the-ocean: Basically I am like an elephant in the wild who needs to be brought down with a dart of elephant tranquilizer! So I needed a more "heavy duty" sleep aid like SEROQUEL. A relative of mine takes about 700mg daily for schizo-affective disorder... There is no way in hell I could take a dosage like that, because 100mg alone is enough to knock me out cold for hours, swell up my nasal passages completely and dry up my mouth. SEROQUEL does indeed allow me to sleep like a baby for about 8--12 hours, and get plenty of refreshing REM sleep, too. In fact, it is the first good sleep I have had in all my adult years. I am just naturally "wired" by nature, and SEROQUEL eases that. Interestingly, once you awaken, you are not groggy at all... 10 minutes, say, for the fog to lift... and you're good. I have in fact, gained much weight since I've been on psych meds (ten years now) and have developed Type 2 Diabetes as well... but I attribute these developments more to DEPAKOTE... which I'll "diss" on a different page... As a diabetic, I probably should not be taking a drug which metabolizes in the liver (as SEROQUEL does)... It would be prefe M 47 5 years
100mg 1X day
6/29/2010
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 5  bi polar it is wonderful to experience deep sleep. F 46
300 1X day
6/29/2010
 4  Bipolar, OCD, BDD, Insomnia Drowsiness, Increased Appetite I think that this drug has helped me greatly in overcoming my BDD, and it totally levels out my moods, but I never really feel any intense emotions... It's not helping with the OCD part, if anything it's made it worse. But I no longer freak out in situations I can't control. I'm just more organized if anything. It helps with my lack of sleep, it's easy for me to get 8+ hours a night when before I started taking Seroquel I slept maybe three hours a night if that. It does take me awhile to actually get up and function in the morning when usually I'd be up and fully alert within a minute. No weight gain as I'm good at managing my weight, but I do feel hungry ALL THE TIME. But self control helps, lol. F 16 6 weeks
100mg 1X day
6/29/2010
 2  Bipolar type II Nightmares, anxiety, short term memory loss, decrease in appetite, stuttering, passive-aggressive behavior, uncontrollable eye movements, trouble concentrating, From taking this drug I got nothing but waking up in the middle of the night sweating from nightmares. I also lost my ability to communicate and express how I felt which made things worse with the friendships I had with people, which eventually destroyed those relationships and made me more depressed. I now know how people feel when they say these drugs turn you into zombies. I have vowed to never again take this drug ever again to let big pharma get a hold of my life. I have never been more lonely than I have been after taking this drug, I started to develop mild schizophrenia during and after it; not to mention severe withdrawal and "brain zaps". Do yourself a favor and stay away from this drug, oh by the way I use to like smoking bud from time to time but I can't even do that now because it worsens my anxiety and panic attacks. I think the worst part was not being able to just be myself, I felt as if I was desperate most of the time when at social functions and the uncontrollable eye movement only made things worse with the opposite sex. F* Seroquel. M 23 1 months
25mg 2X day
6/23/2010
 4  bipolar - episode of mania Drowsiness, difficulty focusing, no motivation, can't stop eating It does seem to work it brought me back to earth. That having been said I'm going to stop taking it the side effects are too much especially the lack of motivation and drowsiness. It's a real effort to accomplish anything significant which is a bit of a problem. M 32 45 days
100 1X day
6/17/2010
 5  Bi-Polar II w/Pyschotic Tendencies A little twitchy- But only noticeable to myself. No weight gain, no increased appetite, no high cholesterol, no TD, no headaches, no insomnia, no bad side-effects at all. Seroquel has greatly improved my existence. I no longer have hallucinations, delusions, depression, insomnia, nightmares, or suicidal thoughts. Since Seroquel came into my life I have been free and easy to live life to it's fullest. I believe Seroquel, combined with my morning dose of Paxil 20mg has saved my life. As someone said before, Seroquel puts my demons to sleep. <3 F 20 2 years
25 MG 1X day
6/16/2010
 1  Bipolar Disorder, Insomnia Overeating, fatigue, no sex drive, feeling foggy, depression After stopping this medication, I have been UNABLE to sleep! I have taken several medications (including Ambien) and I still cannot sleep through the night. Seroquel gave me terrible withdrawls and killed my ability to SLEEP!! F 24 5 years
400 1X O
6/11/2010
 5  bipolar disorder/insomnia/anxiety slightly more sleep, and heartburn this drug has been my savior for me atleast( i know different people handle drugs differently) gets me to sleep good i'll take and extra hour or so of sleep a day over no more than 1~3 hours per day ^.^ and as for the heartburn well it didnt start till i started taking it would probably go away if i stopped drinking mt. dew so much, has completely eliminated my insomnia, my moods are much more stable now and my life has become very carefree and happy since i started seroquel. also taken along with 150mg a day of effexor xr that i take for depression. M 28 5 months
200mg 2X day
6/10/2010
Email
 4  Insomnia wt gain 60 lbs, hi cholesterol F 59 3 years
400 mg 1X day
6/10/2010
 3  Bipolar, OCD Loss of Libido, Munchies, Weight Gain, Agitation, Anxiety, Depression, Learning Disorder. I was put on this when I was 14, I constantly had to rearrange my class schedules in high school because this medication made me feel sedated the entire day, I was eventually put in home school because I had absolutely no credits by the end of my first year. Seroquel for me did have a huge therapeutic tendency when I took it at the right time but the day after was a completely different story. I would constantly be agitated and fatigued and had a lot of difficulties functioning in the real world. But once I got used to juggling my social life with the side effects things somehow worked out especially when I was taking an anti-convulsant with the seroquel. About a year ago I was taken off of this drug because I had gone from 120 pounds to 160 and was severely anxious and depressed, I then got a balance disorder shortly afterwards and was put back on it and eventually taken off of it again when I noticed that It was making me really moody and depressed. M 21 7 years
25 MG 1X day
6/9/2010
 2  Major depressive disorder Tiredness, dry mouth, stomach problems, urinary frequency, urinary incontinence, constant sinus, low white cell counts. The tiredness near killed me, have found it very difficult to function - just need sleep. I found that abour 15-20mins after taking Seroquel my legs would become restless - I told my psychiatrist, who gave me Valium for that. Constantly fighting off hunger. Terrible wind and stomach pains, and possibly the worst side effect, which I had no idea was a side effect until I weaned myself off them - urinary leakage/incontinence. Gross. I am only 47, and that really killed my confidence. Have only been off it for 3 weeks, and I no longer stink of pee, and have dry duds ! I'll have to try and cope with my mind running amok, because I won't have my body doing it ! Also had low white cell counts and kept getting boils. F 47 8 months
100mg 1X day
6/8/2010
 1  Insomnia Extreme fatigue, clumziness, cannot focus, blurred vision My doctor gave me 10 Seroquel pills to see if it would help put me to sleep at night-I've only ever been able to sleep during the day and I hate it. I have 4 left in the bottle b/c I refuse to take them. I only took 1 tiny pill at a time-cannot remember the dosage but I think it was 25? This pill knocked me on my ass. It would put me out for 12 hours at a time-wake up-stumble to the bathroom, attempt to shower or get dressed, and would end up collapsing back onto the bed for another 4 hours. After I'd finally be able to wake up (which was HARD) I was in a fog for the rest of the day. No drug has ever gripped me the way this one has, it is completely overpowering and I have not a small woman. I understand that meds affect people in different ways, but based on my experiences with it, I would never recommend anyone going anywhere near this stuff. F 30 6 days
1X AN
6/8/2010
 1  Bipolar Rapid cycle Hair Loss, Rash, Canker Sores, Joint Pain, High Blood Pressure, Vivid Dark Dream, Stupor, Weight Gain, and the List goes on. I started with 25 mgs. of Seroquel and worked fine. As with others I too would wake up in the morning to find empty cereal boxes, jars of jam GONE! But my Dr. loved my progess so much he upped the dose again and again. Now that I am on 150mg XR I am $%^$%^$^ @#&* (Swear Words) The last 6 months I have complained of extreme hair loss, a rapidly spreading rash (3 different Doctors couldn't explain it, not even my Psych) joint pain so severe when I get up I have to hold on to furniture and can't sit for more then 15 minutes without being sooo stiff it at times seems unbearable. My legs ache continually, when I am at church I have to leave because of the sweating. I now can add high blood pressure, anemia, canker sores and again the list goes on. What really upsets me is I have been compaining of these side effects for 6 months without anyone helping me. My Dr. is soo pleased with my progress, I am actually stable for the first time in years that he is not listening to me. At what expense is it worth it???? Yeah, having my moods stable is great but so what. I have no life. I look life crap and feel like crap. So what to do now?? Just wanted to let someone else know if they are suffering with the same issues as me, get a second opinion regarding the side effects since my Dr. wasn't aware of all of them are just played mute at my expense. F 50 1 years
150 xr 1X day
6/7/2010
Email
 4  insomnia, bipolar II I woke up daily with food wrappers in my bed and only vaguely remember eating, difficulty waking up for the first week or so. It worked really well but there are some crazy long-term side effects. F 20 2.5 months
150 1X day
6/3/2010
 4  bi polar OCD pain Weight gain from 148 lbs(size 12-14) to 183 lbs(size 16). Memory issues both long and short term.Confusion,can't seem to keep linear thought processes, eyesight worsening, have to reason with myself not to eat, no willpower to resist! Very sensitive to sun and heat.Muscle cramps, chest pains, high cholesterol. Having listed the side effects, I am willing to live with them, because seroquel has helped me tremendously.I take 200 of the plain each night, along with 2@ 37.5 effexor xr for depression and fibromyalgia-like pains.Within 1 hour, I sleep serenely, and wake refreshed. Sleep, a precious commodity for bipolar people!I must stick to a rigid schedule or the side effects worsen rapidly.I experienced the rapid weight gain when I was put on seroquel XR- I gained 20 lbs in 3 months, and could not sleep.Back to plain seroquel and lost 5 lbs only.I take this med because it has quieted down the psychosis, allows me to order my thoughts, keeps me more even when combined with a rigid schedule.I can do some sustained work without going off the deep end, drive places without panicking, leave my house to do basic stuff, am able to live a more normal life within very confined parameters, have more empathy for others as my own condition is not the only thing in my brain... But, I have yet to complete any major projects, have less ability to concentrate, there is weight gain, it's a trade off because it is a novelty to feel 'sane' for extended periods although somewhat confused, less giving in to whatever crazy urges that have ruined my life, and more happiness, less psychic/emotional pain!I combine meds with a very quiet life. F 57 5 years
200 1X day
6/2/2010
 3  bpd anxiety stunned, extremely irritable, hungry all the time I feel that my anxiety has lessened. But I doubt I will stay on it because of the irritability factor. I scare myself. F 58 6 days
25 1X day
6/2/2010
 5  insomnia, OCD, anxiety. dry mouth, nothin' else. it is a wonderful antipsychotic to calm your mind, allow u to sleep like a baby and to reduce symptoms of anxiety. be warning to take it before driving, having sex, having exams or excessive work. for the first time, i do not shit an antipsychotic for akathisia or weight gain. M 24 7 days
50 mg 2X day
6/1/2010

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