SEROQUEL Reviews (QUETIAPINE FUMARATE)

Average Rating: 2.9 (1505 Ratings)

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 ANTIPSYCHOTICS ANTIMANICS

 Type: Rx Drug

  

SEROQUEL  (QUETIAPINE FUMARATE):  This medication is used to treat certain mental/mood conditions (such as schizophrenia, bipolar disorder, sudden episodes of mania or depression associated with bipolar disorder). Quetiapine is known as an anti-psychotic drug (atypical type). It works by helping to restore the balance of certain natural substances (neurotransmitters) in the brain. This medication can decrease hallucinations and improve your concentration. It helps you to think more clearly and positively about yourself, feel less nervous, and take a more active part in everyday life. It may also improve your mood, sleep, appetite, and energy level. Quetiapine can help prevent severe mood swings or decrease how often mood swings occur.   FDA Approval Date: 2005-10-04 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on SEROQUEL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR SEROQUELCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  Bi-Polar Disorder Tremendous Weight Gain, Lack of energy Seroquel has done wonders for my bi-polar disorder, but I have gained 100lbs in 4 years time. I was 150lbs when starting and am now 247lbs. This is a salt-based medicine which leads to the weight gain, love the drug hate the side effects. I basically have to choose between being sick or crazy. For now Im living with the excess weight gain, but unfortunately my body cannot keep taking such a beating. Great drug, but please do not use it for long term purposes you will become hooked and the side effects will take a major toll on your health. M 26 4 years
300mg 1X day
4/23/2011
 3  depression and anxiety Neurological symptoms: numbness and tingling in feet and legs, tripping and falling, severe enough that I was tested for MS. After stopping Seroquel, symptoms improved without reoccurrence. It did improve my depression and anxiety. From what I have researched, my side effects were very rare. F 33 1 years
200 1X day
4/21/2011
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 1  sleep/possible bi-polar II disorder Weight gain, high cholesterol, high triglycerides I was prescribed Seroquel for sleep/possible bi-polar II disorder. I had full blood work done prior to taking it and everything was within normal range. After two weeks, I had packed on 15 pounds. Over the course of the six months that I took 100mg per day, I had gained over 20 pounds. I had follow up blood work done at that point and my cholesterol and triglyceride levels were off the charts! It was as if I had eaten nothing but cheeseburgers and milkshakes for breakfast, lunch and dinner the whole time I took it when realistically, I hadn't changed my diet at all. My levels were that dangerously high. I immediately contact my prescribing doctor and told her I wanted off the medication asap. I weaned off it over a three week period. It's been about a year since I'm off it. Some of the weight has come off and I'm not as 'puffy' as I was. My blood work is still not great but is slowly going back to normal. This medication was GREAT for sleep but when it has such horrible side effects, it's not worth the BIG sleep it could put you in. F 36 6 months
100 1X day
4/20/2011
 4  Depression and anxiety Dry mouth and daytime sedation. I have chronic depression and anxiety and, over the years, was prescribed the more common SSRIs, SNRIs, and NDRIs with little to no effect on symptomatology. After beginning Seroquel initially for irritability, anxiety, and insomnia, I noticed improvement in as little as one week. I am approaching my 3rd week on Seroquel and, aside from daytime sleepiness and dry mouth, I am quite satisfied. I have noticed an overall improvement in my mood, ruminative/obsessive thinking, anxiety, irritability, and sleep. M 44 20 days
100 MG 1X day
4/11/2011
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 4  insonima and high anxiety it would turn me into a zombie state so i could only take it just before going to bed. its really helped with being able to sleep and my overall anxiety is a bit lower. I havent had any side affects from seroquel. F 25 3 years
600 mg 1X day
4/7/2011
 2  OCD, panic disorder destroys sleep completely. digestion problems, gave me chronic abdominal pain on my right, which would get worse after food even with low amount of fat, destroys memory and impairs you cognitively. yes it took care of my ocd very well - instantly. i was on 25 mg-50 mg a day for about 3 months. then it started worsening ocd and panic attacks. i had to reduce my intake and took it as needed. it worked well. even severe ocd episodes were reduced immediately. but as soon as i started taking it regularly again, the adverse effects came back. after about 2 years of using it on and off (3-10 times a month) i developed an almost chronic abdominal pain on my right and jaundice. i went off it for about 6 months and it subsided. however, it destroyed my sleep. i had a very hard time falling asleep and i was waking up every 2 hours. it's next to impossible to get your sleep back after this medication, i tried very hard (excluded all caffeine, tried to maintain good sleep hygiene, etc) never actually got it back completely. even if you do start sleeping a bit better after being off seroquel for many months, taking one 25 mg pill will throw you back to square one. i think when you're on these medications you really should listen to your body more than to your doctor sometimes and you should never ignore pains. yes for some people the benefit outweighs the side effects. but in my case it was replacing one problem with a bunch of others. F 37 3 years
25-100 MG 1X day
3/31/2011
 1  Insomnia Blurred vision Palpitations Could not swallow Loss of self-control – smoking; major eating Lethargy Apathy Memory loss Hair loss Fatigue Weight gain (not very much but bothered me lots) Dry mouth The WORST drug I have ever taken. Taken for sleep. Ended up taking 25 - 50 mg. nightly. Would knock me out BUT got palpitations, Would need crackers then sweets (for no reason) including chocolate (which I hate). (I would have eaten a cardboard box). Could not swallow (even fluids) Finally would go to sleep and wake up breathing chocolate. Last straw was I have 2 cats and chocolate is toxic to cats. I dropped some chocolate and normally would have searched the floor with a magnifying glass but on that night (4:00 AM) I did not care enough to look and just covered area with a sheet. (December 26, 2010) never took it again. Question: Although I was *only* on 25-50 mg. nightly, it had MAJOR effects. It has been 3 months! But 2 weeks ago, I developed severe bone / muscle / joint pain (hip, sacroiliac area) and ankle swelling to the point I cannot hardly walk or get to my doctor due to pain. Could this be a late withdrawel reaction? F 40 7 months
25 - 50 MG 1X AN
3/27/2011
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 3  Borderline Personality Disorder MAJOR WEIGHT GAIN. Heart palpitations, dry mouth, slurred speach, hang-over feeling, loss of memory and concentration, sedated, extreme hunger. This drug worked wonders for my mood swings and insomnia. However I gained 60 pounds in 1 year! After taking 100 mg/per day for a year and a half, I was forced to stop taking it because I gained way too much weight in such a short amount of time. Now, 2 years later, I was just diagnosed with diabetes. and the doc. said its becuase of the Seroquel. I have not been able to lose the weight with dieting and excersize. i am only 23 and am now stuck with a major self esteem issue because i look like a fat cow. seroquel was great for what i needed it for - but PLEASE stop taking it if youre on it (with the help of a doctor, of course!). ist not worth the long term effects of your health. If you have any questions feel free to email me: [email protected] (no spam please) -- Rachel F 23 1.5 years
100 mg 1X day
3/23/2011
 3  Anxiety & Depression The worst thing is the tiredness. I was almost passing out the first few days. I also had dry mouth. I noticed that after a few weeks that my sexual libido went way up. It also makes sex more pleasurable for me. I also noticed that my food tastes better to me and my appetite is way up. That's not a good thing. M 39 20 days
50 2X day
3/22/2011
 2  Schizophrenia Seroquel caused me to have a rapid heartbeat, uncontrollable shaking of the hands, memory and coordination problems, confusion and loss of awareness. I ended up in a Mental Hospital for two weeks because of this drug. I started on 600mg at night and then Psychiatrist increased to 800mg. I could not think clearly, it affected my memory, I experienced acute confusion which resulted in me not being aware of where I was. I felt like I had lost control of my mind, a truly frightening experience. It had no effect on the paranoid delusions I was suffering from, it made me suicidal and all these symptoms continued for weeks after stopping the drug. Eventually these horrible side effects subsided, and I am now stable on Zyprexa (Olanzapine). This drug may work for some people, but for me it was a living nightmare. M 28 14 days
800mg 1X day
3/21/2011
 3  Self-destructive behaviors/insomnia Depression improved dramatically over time, insomnia disappeared, no major side effects but now after so many years somewhat concerned about long term dangers of Seroquel 300mg/Effexor XR 150mg. I plan to taper meds as soon as I move out on my own. I know still living at home under the tremendous stress/anxiety I am under, it is not a good time yet to get off meds which help at the moment cope better with my living situation. My father/brother alcoholic and my my Depressed/Borderline Blind elderly mother who depends on me for everything. Whatever you decide please consult with your doctor first. God bless us all and free us once and for all from Mental Illness. Awi :) F 43 6 years
300mg 1X day
3/20/2011
 1  Depression Seroquel caused severe restlessness to the point it felt like my skin was being torn off, emotional liability, unusual behavior, nightmares and horridly painful muscle spasms. I had to put rolled up wash clothes in my hands at night so my fingers wouldn't curl up into my palm.I jerked so badly I slept in an upright recliner. It make me so sedated I was unaware of what was happening. One night I ended up in the Emergency Room with Seroquel-induced Pancreatitis/Diabetes (this is a documented side effect). I spent 3 months in the hospital with a tube down my nose.A physician diagnosed me with the worse case of drug toxicity he'd ever seen so I went off the Seroquel. Make sure someone who really knows you can monitor your behavior when on Seroquel. A doctor who only prescribes this may NOT notice how it has caused you to became erratic (Iatrogenic Illness).Seroquel is a major anti-psychotic and very very powerful.Consider NOT taking this drug at all. M 52 2 years
300mg 1X day
3/18/2011
 4  Bipolar, anxiety, BPD, ASPD cant not take it or ill not sleep but dosnt help a lot to sleep weight gain i want to stop but every time i try i cant sleep get agitated worked up agressive anxious i would like to get off seroquel im currently taking the XR 300mg morning and 900mg at night F 21 5 years
1200mg 2X day
3/13/2011
 5  bi-polar, anxiety, depression Weight gain, higher sugar Been the best thing for me. Yes, I experienced weight gain, but I take into account that it's made my bi-polar managable, so willing to put up with the side effects. I sleep at night now, and my moods have stabalized. It was the best thing I could have done, it's working well for me. M 51 2 years
300 1X day
3/4/2011
 1  Paranoid Schizophrenia Seroquel caused me acute psychosis, visions and voices. It caused what it was supposed to heal. Affected the dopamine-center so that it caused the effects of early tardive dyskinesia in an age of 24. Trouble urinating. Blunt/drugged down feeling through out the day. Not a recommended medicine. Stay away if you can. WARNING: Causes severe blunt/drugged down feeling, tardive dyskinesia and Parkinsonism. M 24 1 months
350 1X day
2/28/2011
 1  depression Bad, likely permanent damage to abdomen/colon/digestion. Can no longer eat a large variety of foods. Weight loss, extremely low mood, suicidal ideation Began at 25mg as an addition to Cymbalta. No effect on mood; upped to 50mg. Great for mood, but immediate, severe bloating/hardening of abdomen esp ascending colon. Dropped to 25mg with immediate cessation of abdominal symptoms. A few weeks later, asked my doctor if I could return to 50mg, as I really appreciated the cognitive boost of 50mg. I knew the bloating would return but felt I might be able to control it perhaps by managing diet; otherwise go off the drug completely. Bloating came back immediately at 50mg, was unable to control it, so tapered down to 0mg as per doctor's instructions. However, this time the bloating, rock-hard feeling in my colon did not go away and has been with me for 8 months. Symptoms vary in severity depending on what I eat. There is huge swath of foods I can no longer consume. This, plus the shoulder-shrugging, "there's no one who will help you with this" has led to bad depression and serious consideration of comitting suicide. I will be seeing a gastroenterologist soon, but I'd essentially been ignored until I got very angry with my doctor. M 47
50mg 1X day
2/19/2011
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 5  Bipolar None Ive been taking it on and off but I like that it makes me high and sedated. F 18 4 years
400 1X day
2/13/2011
 1  insomnia Nothing. I'm now dying to withdrawal. Seroquel is garbage drug used to treat "mental health" problems. Constantly monitor your blood glucose and cortisol levels. Seroquel can elevate these (adrenergic blockade). YOU CAN DIE TO WITHDRAWAL! INFO: Do not just stop if. AFAIK You should withdraw to long-acting alpha1 blocker (alpha2?) and carefully monitor you blood glucose and cortisol levels as they can kill you (=> diabetes). YOU CANNOT SAFELY WITHDRAW FROM HIGH > 400MG/NIGHT DOSES (DOPAMINE BLOCKADE) DO NOT CHANGE DOSAGE WITHOUT HELP. YOU CAN DIE. GO TO EXPENSIVE AND REAL PRIVATE DRUG REHAB CLINIC (COSTS LOTS OF $$$) BUT THATS THE ONLY WAY I THINK. BE VERY CAREFUL THOUGHT BECAUSE "HELPFUL" DOCTORS CAN JUST KILL YOU. YOU NEED *REAL* PROFESSIONAL HELP. DO NOT USE SSRIs. M 30 3 years
400MG 1X day
1/30/2011
 1  bipolar disorder + extreme insomnia Complete psychological and physical deterioration: ataxia, tremors, seizures, depression + suicidal thoughts, severe memory loss, deficits in logical thinking, aphasia, myoclonus, and hallucinations after taking my dose if I did not fall asleep within a half hour.Due to my already terrible insomnia getting aggravated by other bipolar medications, my doctor "had no problems" with me taking as much as 1200 mgs of this medication nightly (he supplemented my maximum allowed pharmacy dosage with free samples), and made no indication to me that such a dose could be dangerous. . I cannot remember the length of time I was on Seroquel, but during this period I suffered immensely. I shook so terribly that I could not sign my name on receipts or eat with eating utensils, had such difficulty thinking that I failed out of school, and somewhere around the time I realized I was having total black out periods, I began falling a lot while walking, and was hospitalized for a week for suicidality. Despite the fact that I had begun to show severe neurological decline in the entrance physical (could not subtract 7 from 100 or stand on one leg w/o falling) and my overseeing hospital physician acknowledged that I was probably being overmedicated already, dosages of some of my other meds were increased and a new one was even added. Shortly after leaving said hospital, I was hospitalized for seizure activity. Here, it was noted in my chart (I don't remember anything other than getting to the hospital) that I completely lost the ability to speak and could only grunt for a period of time. After the seizures were under control, I then also had fits of myoclonic jerks and could barely speak. It took me almost a full year to taper off of this medication (while the others took only a few months at most) and regain control of my life. Although I was also on various other medications, this was the only one I took at a high dose. For three years I was prescribed more and more of these "relatively safe" drugs, and I was almost completely nonfunctional for two of th F 22
900-1200mg 1X day
1/30/2011
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 1  Anxiety Bad side effects M 60
200 1X day
1/30/2011
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