ZYPREXA Reviews (OLANZAPINE)

Average Rating: 2.5 (585 Ratings)

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 ANTIPSYCHOTICS ANTIMANICS

 Type: Rx Drug

  

ZYPREXA  (OLANZAPINE):  Olanzapine is used to treat certain mental/mood conditions (such as schizophrenia, bipolar disorder). It may also be used in combination with other medication to treat depression. This medication can help to decrease hallucinations and help you to think more clearly and positively about yourself, feel less agitated, and take a more active part in everyday life. Olanzapine belongs to a class of drugs called atypical antipsychotics. It works by helping to restore the balance of certain natural substances in the brain. Talk to the doctor about the risks and benefits of treatment (especially when used by teenagers). See also Precautions section.   FDA Approval Date: 1997-09-09 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR ZYPREXACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  As a mood stabilizer for Bipolar Suprisingly, the only side effect I really notice is sleeping for 10-12 hours a night. I do feel a bit lethargic during the day, but nothing too bad. Overall its probably been the softest med, side effect wise, that I've ever taken. I take 10mg of it along with lexapro, the lexapro keeps me out of the deep depressions, and the zyprexa keeps me from getting too manic off the lexapro. Funny how that works lol. Overall though I've been very impressed with the zyprexa....worked fast and works well. I've put 10-12 lbs on in the couple of months I've been on it....but the gain has seemed to stabilize now (hopefully). I'll need to be on meds the rest of my life though, and unfortunately, I'm not sure I'm willing to take the chance of developing diabetes, or cholesterol problems, down the road. And zyprexa's track record in those area's isn't very good. I think zyprexa's awesome for what it does, but I don't think its a good long term choice. I am going to miss the effectiveness though. But I'd rather have a little safer long term mood stabilizer....even if it is less effective. M 46 60 days
10/21/2009
 5  anxieyt, PTSD, Irrational fears I know that Zyprea has know metabolic side effects, but it has been a life saving drug for me Shortly after I started taking it, it was like the veil being lifted from an aweful nightmare. To date no major side effects, I exercise regularly and and am very consicous of my diet. No major side effects for me other than fatique when my dosage was increased zyprexa has been a "miracle" drug for me. Thank you Eli Lilly for producing it!! M 46
5/17/2009
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 5  bipolar 10 lb. weight gain, sleep good but tired upon waking for 30 min. or so I had been taking wellbutrin and depakote for the last several years and they had quit helping. The zyprexa has been excellant for bipolar. Has stopped most needless worrying. I am much calmer. Some might say it takes away personality but without it I tend to be manic. My employer seems to like the calmer me. So far its great. I needed the 10 lbs. as I lost 45 due to cancer treatment and I need another 10 and I will be happy with that. M 46 50 days
4/24/2005
 5  GAD & major depressive disorder Huge appetite, slightly forgetful, Feel a bit sluggish for the first 30 mins after waking up. Shaky hands in the early to mid morning. I have suffered with general anxiety disorder and major depression since a teenager which has got progressively worse over the years. I 1997 I was hospitalised twice for major depression and again in 1998. I was prescribed Leponex, a very similar drug to Zyprexor. I felt better immediately but my doc took me off it because of the issue with blood testing. Years passed and I forgot about Leponex. I tried Prozac, Ciplapram, (Depramil) cognitive therapy and psychotherapy on and off for years. Nothing ever took away the continuous anxiety, unwarranted guilt, feelings of hopelessness, racing thoughts and varying depressive episodes. My life, my choices and my thinking has been crippled with this awful condition for most of my life. I have almost become a recluse. Over the last two years I have slipped into suicidal depression. Ten days ago I told my psychiatrist how wonderful Leponex made me feel in 1997. He put me on Zyprexa 5mg for 7 days then 10mg to follow and warned me about the possible weight gain. Fortunately I am a tall thin guy and I don’t mind something that will increase my appetite as I eat poorly. The following day I felt great almost immediately. No anxiety, no panic attacks, no dark pits of hellish depression. Ten days later I want to declare to the world that this is nothing short of a miracle, a life saving drug for me. I feel wonderful and Zyprexa is AMAZING! I am now calmer, I can concentrate better, I am more confident. M 46 10 days
10mg 1X day
9/28/2012
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 4  bipolar 1 Weight gain like everybody does. I'm trying to FORCE myself away from the table since I've gained the weight because I EAT MORE. And I think it causes diabetes because I CRAVE sugar. Anyway, I love it and just wish it didn't cause weight gain and possibly diabetes. I'm staying with it for another year to see if I can drop some weight and level off. Seems that developing diabetes usually occurs within a year of starting, so I've passed that mark.It just works so well! F 46 1 years
9/11/2006
 4  bipolar 1 Lots of weight gain! I ate a lot more, had a bigger appetite. Craved carbs and sugar.No other side effects. It works so well on my mania, anxiety, insomnia etc that I'm willing to deal with the weight gain. I try to resist carbs and sugar binges as much as I can. I'm afraid of the diabetes scare. F 46 1 years
9/11/2006
 4  depression and anxiety Gained 25 pounds in a month Works well for severe depression and anxiety. Will aleve intense anger very quickly. Great drug if necessary but your stomach will grow. M 46 6 months
15
2/17/2016
 1  Bi-Polar paresthesia, peripheral edema I lost all sensations in my hands and my feet were so swollen I couldn't walk. I thought the side effects would go away but they did not. Finally stopped the drug a month later and have permanent damage to my right hand, still unable to grasp small objects. Sublingual B12 helped my hands as much as it could. F 46 1 months
8/28/2009
 1  ptsd raised blood sugar, compounded eating disorder problems as it made me ravenously hungry and i would binge eat, somewhat it worked great in terms of helping me sleep and stabilize when i was having panic attacks or flashbacks. unfortunately, the side effects were so severe that i had to switch to another medication (abilify) which doesn't help as much but hasn't had any side effects thus far. F 46 8 months
9/10/2004
 1  Bipolar Weight gain,very tired, confusion with memory loss. I agree zyprexa is a poor performing drug for many and should be taken off the market. M 46 5 months
40 1X day
3/28/2012
 1  Anxiety and depression Weight gain (50 lbs), craved sweets, drowsiness, passed out in public twice, tardive dyskinesia I took Zyprexa for four years and it wrecked my life. I gained 60 pounds, I went from a size 4 to a size 16. Before going on Zyprexa I took dance classes 6-8 days a week, and was in a dance troupe. After taking Zyprexa I was so drained of energy, I could barely get out of bed. So, I stopped pursuing my life long passion of dancing. I went from being one of the top employees in my division to a zombie, who couldn't string a sentence together. The drug made me so tired it affected my attendance at work. It didn't take long before I was fired. On top of that, many people in my company were gossiping about how fat and weird I had become. I also crashed my car three times while on this drug. I had to move in with my Mother, because my life was such a mess. Thank god for my Mother - because she finally saw what had happened to me. I stopped the Zyprexa. The withdrawals were horrible. For a good six months, I had severe mania, anxiety and insomnia. I threw up constantly. Those were just the physical withdrawal symptoms. It took a full two years before my cognitive abilities returned: my mental sharpness, sense of judgment, logic and reasoning. I also developed a mild form of tardive dyskinesia, which I still have. This all happened eight years ago, yes I lost the weight and I reclaimed my life. Doctors like to throw this drug and others like Abilify at people who are not bipolar or psychotic, but don't fall for that. Please, please think very carefully before taking this drug. F 46 4 years
2 mg 2X day
9/21/2010
 1  depression +3 pitting edema-this is when you have swelling, press on the area and a "dent" remains Ending up going from PCP's office by ambulance to ER due to arrythmia. Now have a permanent life threatening heart condition from this medication since the arrythmia can induce congestive heart failure (CHF). Lost 30# of fluid after 3 days in hospital and in compression hose from toes to upper thighs in the dog days of summer, not very pleasant, comfortable nor stylish! Now on 3 heart meds for life. Thank you, Zyprexa..... F 46 14 days
2.5mg 1X day
5/26/2010
 5  Depression weight gain but able to lose weight w diet and exercise Zyprexa saved my life. F 45 6 months
5 mg 1X day
9/1/2011
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 4  Depression & AADD dizzy first few days, bizarre craving for sweet foods...ate an entire lemon pie one night...in bed! Contacting my doctor now about trouble breathing last night, either a dream or real? Definitely helped with balancing my moods...much more focused. I combine my 10 mg tablet with 18 mg. of Concerta. So far, so good...except for that breathing problem (maybe not so good). M 45 7 days
12/15/2005
 3  bipolar II I have been on zyprexa for a couple of years. I just got my bloodwork back and I have dangerously high cholesterol. We are going to have to try and find something else. The zyprexa did help me with suicidal thoughts F 45 2 years
8/3/2006
 3  Bi-Polarity & Borderline PD Obesity, minor facial ticks, devoid of emotion or desire or most feelings. Overall, just rehearsing old normal behaviours without the emotional investment. Going through the motions, so to speak. Olanzapine is probably the best Psychiatry has to offer the extremely ill. It's a Purgatorial drug, no question, but it stops self-harm and harming others so long as it works on you, the individual. Some individuals are immune to all medications, so don't forget that Psychiatry is not mathematics. If they say they don't know, then they're being honest. That is science. At the end of the day, it comes down to this: do you want a certain quality of life with as little suffering as possible, despite the fact you will die earlier than most? Or, would you like to suffer intolerably until you're 75 years-of-age, so long as you don't stick your head in an oven beforehand? It is a lesser of two evils drug. PS: I chose the former for 8-years, chose the latter for 6-months, but now am wearing the consequences of it. Can I live with it? Who knows? Can I live without it? Who knows? But I think the inevitable will happen, and I'll forever futilely fight the reason they put me on that shit in the first-place. Welcome to the real world! Life's a bitch, and as the great Philip Roth stated: 'You have to hand it to life for the sheer amount of tools it has its disposal to bring a man down'. All the best. M 45 8 years
10mg night
9/16/2015
 2  Psychosis Rapid weight gain, constipation, odd sensations in arms and legs. Stopped psychotic thoughts and behaviour. Discontinued drug due to weight gain. M 45 1 months
1/31/2005
 1  Bipolar 1 Gained weight so much weight. Lethargic. No way to live life. Took about 5 weeks to get in my system. Never should have stayed on it 2 years F 45 2 years
1X day
6/14/2013
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 1  Anxiety Nausea and shakes feels like i have the flu and tired Dont take it F 45 1 months
5mg to 2.5
12/16/2016
 1  freak small elevation Feel like shit,lost my spiritually, and have not been able to eat due to so much body fat and weight gain. Can someone tell me if the weight will come off. I have taken myself off it for 8 weeks now, hope l get better. Have lost 5 kilo, another 5 to go, no sex drive because in so fat. Can anyone help. I am not usually suffering mental health problems, help. Help, i need a swim . F 45 1 weeks
5/29/2014
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