ARIMIDEX Reviews (ANASTROZOLE)

Average Rating: 2.5 (1431 Ratings)

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 ANTINEOPLASTICS AROMATASE INHIBITORS

 Type: Rx Drug

  

ARIMIDEX  (ANASTROZOLE):  Anastrozole is used to treat breast cancer in women after menopause. Some breast cancers are made to grow faster by a natural hormone called estrogen. Anastrozole decreases the amount of estrogen the body makes and helps to slow or reverse the growth of these breast cancers.   FDA Approval Date: 1995-12-27 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on ARIMIDEX: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR ARIMIDEXCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  Ductal Breast Cancer-Stage 2,1 node severe joint and bone pain, abdominal weight gain - impossible to lose, fatigue, difficulty sleeping, itchiness, hot flashes taking fish oil - wonder drug! 2000 mg. daily ...has helped tremendously with pain; pain still severe but frequency and duration has diminished. switched to tamoxifen but hot flashes were unbearable so went back to anastrazole. found no difference between arimidex and generic. F 55 21 months
1mg 1X day
9/22/2011
 1  Breast Cancer Joint pain, weight gain, hot flashes, vaginal dryness, memory loss, tingling in feet, brittle bones, tiredness I have been on Arimidex for 3 years. My side affects have worsen. I have gained 20 lbs and cannot lose it even tried dieting. The joing pain is awful and I fractured a rib by bending over to get something out of the floorboard of my car. I am tired all the time and have to take a nap when I get home from work. F 64 3 years
1 mg 1X day
9/15/2011
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 2  breast cancer Extreme joint and muscle pain, short term memory loss and confusion, severe depression (anxiety/panic attacks), tired, weak............. Is there a study of how long people have lived and or their quality of life post five year treatment of Arimidex? F 55 3 years
1mg 1X day
9/13/2011
 2   Joint pain - hands, knees, hips, shoulders, elbows. I have been in remission from RA for years and feel like I am back to the beginning with the pain. Going on an Arimidex vacation with the hope that the SEs subside. This is not the way I want to live my life and hopefully it can be reversed. F 54
10 1X day
9/12/2011
 5  Stg2 Breast Cancer-hormone+ The past 4 years of negative side effects have been challenging, but the alternative is far worse. I just celebrated 5 year, cancer-free anniversary & I'm happy to be alive - side effects & all. F 54
1X day
9/11/2011
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Patient History
 3  stahe 3 breast cancer + lymph node Joint pain, receved dignosis of rheumatoid arthritis 2 years in. I think it is the generic arrimadex, this is when it started. Fatuge, joint swelling, pins and needles in hands and feet, at least 30 hot flashes a day, fuzzy thinking, dizzyness, vaginal dryness and vaginal atrophy, no sex drive, depression I am to affraid to stop taking it because I has such a long (4yr) and 2 diagnosis cancer. took tamaxifen for 2 years and had re occurance so went of arrimadex total of 6 years now on either or drug.. also I had hystorectomy F 46 4 years
1mg 1X day
9/9/2011
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 5  Early stage breast cancer Most of those listed by others, in the last year my cholestorol, blood sugar, and triglycerides began inching up. I have been off arimidex for 2 weeks now and am feeling much better. I have also lost 7.4 lbs. of the 22 lbs I put on while taking the arimidex. I am glad I took the arimidex since I did not have to take chemo or radiation. It was my only treatment other than the bilateral mastectomy that I had. My joint aches, fatigue and carpal tunnel symptoms have already improved greatly. I am certainly not sorry I took it and put up with the side effects but I am very glad to be off of it. F 62 5 years
10 MG 1X day
9/8/2011
 5  STAGE 4 METASTISED BREAST CANCER WITH THE RETURN OF BREAST CANCER,AFTER 45 MONTHS ON CHEMO,I HAD HOT FLASHES VERY BAD,THIS SUBSIDED AFTER THE SECOND MONTH. F 63 5 months
25 1X day
9/8/2011
 3  Stage 1 Breast Cancer no nodes None in the beginning, then started noticing how tired and sore I was. Went from an active lifestyle to incredible fatigue and pain in my hands, feet, lower back and shoulder. No hot flashes, maybe a little weight gain. I was on tamoxifen for 2.5 years and they swiched me over to the arimidex (once I found out it was generic and could afford it.) I figured I did fine on the tamoxifen, felt great, plenty of energy and no noticible pains. Started on arimidex a year ago and within a month, started noticing being tired and achey, was thinking it was old age creeping up on me. Then checked the SE of the arimidex and had an eye opener. So I decided to take a break from the arimidex starting september 1st. Woke up this morning for the first time noticing WOW, I am not sore. Could be a fluke, so going to stay off for the rest of the month. If I continue to improve, will call my oncologist and go from there. I just can't bear the though of feeling this crappy for 2 more years. F 50 1 years
1 mg 1X day
9/7/2011
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 3  Breast Cancer Chronic fatiuge. joint pain; knees and feet Absolutely no energy. Could not get enough sleep. Arms and legs felt very heavy. Swollen feet/ankles. Creaky joints F 41 6 months
1mg 1X day
8/17/2011
 5  For breast cancer; no chemotherapy. i had joint pain and hair thinning. After three years, I developed trigger fingers (middle and ring) and thumbs on both hands and had surgery. No problem thereafter. Some days with pain were worse than others; however, I kept focusing on the fact that I believed Arimidex was the BEST. I began in June 2006 and, happily, ended June 2011. F 73 5 years
1 mg 1X day
8/10/2011
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 3  Breast cancer - 3 nodes positive Joint stiffness, no energy, old lady at 45. Monday my oncologist are scheduling a follow up to decide to stop Anastrozole (Arimidex) and take Tamoxifen. I had my ovaries removed to reduce that risk and be able to take Arimidex because of the risk - 11 months in and I am old... I have 30lbs of weight gain. I was a very active and size 4 woman - now I am huge and my quality of life is obviously challenged. I struggle with my decision... F 45 11 months
1mg 1X day
8/7/2011
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 2  infiltrating ductal br ca Stage 1 after 1st month had severe burning shooting pain from hip to knee. told my oncologist but was told it wasn't the arimidex. Over the next 3 yrs I had increasing pain in knee, saw an orthopedic MD, went thru 3 orthovisc injections, 3 steroid injections with no help. Then this yr pain became worse, developing back pain, dexa scan showed I had developed osteopenia over the past 2 yrs, increasing osteoarthritis and DJD of knees and spine along with 4 bulging discs. The oncologist still is saying it's not the drug. My quality of life has gone from active to barely able to move, using a cane, and after a 10hr work day going home in tears because of the pain. Have used hydrocodone, ultram, aleve, flexeril, with no improvement. I'm 60 but feel like I'm over 80. I decided to stop the med for a couple of days to see what would happen. After only 1 day I am walking without a cane and feeling sooooo much better. I WILL be meeting with my oncologist about either stopping it, reducing the dose, or changing to aromasin although it has the same side effects. All I know is I am not going to continue the next 16 months to complete the 5 yrs of treatment in as much pain as I've been experiencing. I've seen other comments that it's quality of life that's more important and I am now a firm believer. I am a nurse so I did an extensive investigation of the drug and I will be sending my comments to the drug company to add to their list of side effects. F 60 44 months
1 mg 1X day
8/5/2011
Email
 3  breast cancer Bone pain in fingers ,arms, knees, and just all over pain. I have been taking arimidex for 2. years and thought I was in the clear of the side affects. about 6 months ago I started developing the pain in my hands. In the morning I wake up to fingers that I can barely straighten. Knee, leg, and foot pain. Not fun. After reading others side effects and seeing that others have had late side effects, I know that its not all in my head. F 56 2.5 years
1 MG 1X day
7/29/2011
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 2  Bil triple+ IDC Stage 1,clear nodes Constant joint pain and stiffness, muscle weakness and pain, numbness, tingling and muscle spasms in hands and feet. Brain fog, apathy, depression. Loss of balance and falls. Escalating/abnormal liver enzyme values. Weight gain in abdomen. Brittle nails. Zero energy, constant fatigue. Insomnia. For me, it was as bad or even harder then being on chemo, especially in view of the long term (5yr) recommendation for taking the drug. No end. Chemo at least felt finite. I had bilateral mastectomies and sentinel node biopsies (stage 1, clear nodes) followed by chemo: Taxotere and Carboplatin x's 6 and Herceptin for a year. I stayed with the Arimidex for a year and nine months and quit due to the symptoms, especially the escalating liver enzymes and increasing brain fog. I started to feel better within a week, liver enzymes were back to normal within 3 weeks. I still have residual pain and stiffness in joints, especially hands and knees but much better than it was before. I should mention that my oncologists referred to my cancer as "curable" (early catch, not in nodes, ER+, PR+, HER2+) and treatment was aggressive. I also had a total hyst (no ovaries) years ago so - already reduced estrogen production. Stopping Arimidex was a quality of life decision for me which I feel comfortable with in view of my particular history. I'm an RN, this was a well considered decision. I am not advocating for or against the drug, simply sharing my experience. F 53 17 months
1mg 1X day
7/28/2011
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 1  stage 1 breast cancer no nodes invo I took it the first day and felt a sick head pressure and pain through my temples and forehead, not a headache. 2nd day the pressure/pain more intense. Fuzzy brained, couldn't concentrate sleepless, kept waking up tightening in my chest. I quit the meds. as I called the dr. and his nurse said to stop. After two weeks, my sleep is still not normal. It took days for the head pressure to leave. I got Sciatica too. Pain in my fingers. F 67 2 days
20 mg 1X day
7/27/2011
Email
 4  hormone+/invasive breast cancer Joint pain early on, take silicium, omega-3, gingko. Weight gain, gym classes regularly, mountain walking. i am lucky i have been able to cope with the side effects although the reduced level of energy is saddening. I am interested to know whether I will have any side effects when I stop taking A. in October this year. F 68 9.5 years
1 MG 1X day
7/26/2011
Email
 5  Breast cancer - stage 2 Almost constant deep-bone pain; fatigue; severe joint pain; and at least 10 pounds weight gain, mostly in tummy. Had to take a bone building med which was to counter-act the bone loss of Arimidex I've been cancer free a total of seven years, having stopped Arimidex 2 years ago. Although I had to use a diet system to get the weight gain down, all the pains are essentially gone. I've always had arthritis, but that's extent of my pain now. If you can hang on through all the nastiness, I think it's worth it! Face it - the alternative SUCKS!!!! F 69 5 days
1 M 1X day
7/14/2011
Email
 4  Inv BC stage 2/3; nodes - yes; Serious muscle/bone pain to the point that I could hardly walk let alone get out of a chair or climb steps. Shooting leg pains. Pains in hips, knees and ankles. Tingling in hands and feet that stopped on my 2 week hiatus from it. Had to get Handicap Card. Ache all over, all the time. Weight gain. Hot flashes. I originally wrote in Dec 2010. I was having awful side effects and my ankles felt so brittle I could hardly walk. After trying half doses, a 2 week break, aromasin, etc., I asked my dr to put me back on the BRAND. I took nothing for 2 weeks. Have been taking the brand now for over a month and I am feeling so much better. My ankles aren't swollen and they don't feel brittle. I still get tired and have some muscle pain and tingling (lyrica helps that) but now have a quality of life. My ct scan this week was great and all is STABLE. Shame the insurance won't pay the difference but my life is better so I will continue to stay on the brand. F 64 15 months
1mg 1X day
7/13/2011
Email
 1  stage 2 breast cancer so tired al the time and joint pain all over, hands and knees so stiff it takes me a couple of hours after taking pain meds in the morning to get going. wonder if it's worth continuing F 62 1 years
1mg 1X day
7/9/2011
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