Drug Ratings for VALTREX

Average Rating: 3.3 (539 Ratings)

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    Charts & graphs: Reviews Summary for VALTREX  | Top 10 Adverse Effects (reported to FDA)

RATING  REASONSIDE EFFECTS FOR VALTREXCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
sort down sort up F  M  
 2  Cold Sores Depression, headaches, extreme fatigue, irritability, brain fog, feeling spaced out, lack of concentration and memory, anxiety Yes this medication does seem to help get rid of the cold sores but the side effects aren't worth it. Still not feeling myself after being off of it for 3 days. Wondering when side effects will subside. F 27 7 days
7/3/2017

 5  Genital HSV2 Loss of appetite for the first few months, minor but perpetual shaky hands, possibly increased depression and anxiety but already have both, once or more daily lower right back pain or nerve seizing up Got it from a now ex who says they didn't know you had to specifically ask to be tested for herpes. Experienced increased anxiety and depression after about 2 month taking one pill daily, but was already taking meds for those so may be unrelated. I also experience an immense sharp pain in my lower back on the right side at least once daily, usually a couple times. May be just due to the herpes as it's a possible side effect of the virus. But it has possibly made all the difference. Still in my first year and not a single outbreak since my initial one. I believe that Valtrex is a big part of that. Supplementing with lysine and turmeric help greatly as well. F 25 10 months
500mg/day
4/12/2017

 1  Genital Herpes I did not know that Valtrex was causing my deep depression, irritability, anxiety attacks; aggressive behavior and overall darkness in my life because starting the drug coincided with a huge and stressful event in my life. In addition, I had dysthymia and had been on a low-dose of antidepressants for years. Consequently, my doctor thought my worsening depression was a situational problem and not the side effects from the drug. I got so bad at one point that I was on an anti-psychotic drug. I went through almost seven years of torment until I stopped the drug last December Within a week I was feeling better: the darkness had lifted; the anxiety stopped; I was happy for the first time in years. I began to wean off the huge dosage of Wellbutrin and now I am completely stable on 75mg Wellbutrin and 10 mg Prozac. the situational stressor is still a part of my life, but I am at last normal again. DO NOT TAKE THIS DRUG IF YOU HAVE HAD A PREVIOUS DEPRESSION. This drug is useful for certain conditions; however, if a person is prone to depression or has a history of depression this drug is NOT for them as the medication makes all those symptoms exponentially worse. F 68 7 years
1 gm 1X D
4/12/2017

 2  High HSV1 tigers, no outbreaks Dizziness, metallic burning taste in mouth, insomnia, feeling like my skin is crawling, tingling and burning in arms and legs, heart palpitations, increased anxiety and moodiness, uncontrollable crying F 42 1 months
500mg 2x
4/7/2017

 5  Genital herpes Contracted the herpes virus from an idiot ex who never told me he had it. Doctor prescribed me valtrex, I didn't have any bad side effects and it cleared up my breakout instantly. Haven't had a break out since and it's been 3 months on the medication. I do take one once a day. In the beginning I was very depressed, didn't want to get out of bed. But I don't believe it was from side effects of the drug more so just coming to terms w me having the virus from someone I loved and trusted. Needless to say, we broke up. And I've been in a relationship for 7 months, my partner has not contracted the virus and was so supportive when I told her about me having the virus. So for anyone feeling like their love/sex life is over it's not! Like my doctor says, if someone doesn't want to stay w you because of this, then their an idiot and at their just not the one. F 22 3 months
2/18/2017

 3  Hsv2 Dry mouth, red pinpoint spots on my body, rash on face, burning mouth and geographic-looking tongue, headaches and body aches Wondering if anyone else had tongue issues after taking valtrex (valacyclovir ) F 37 1 days
500mg
2/12/2017

 1  Shingles Had severe allergic reaction and ended up in ER. Shortness of breath and tightness in chest. Had to be taken off med!! F 54 5 days
1gram
1/6/2017

 1  Cold sores Nausea, vomiting, chills, headache, abdominal pain, lower back pain, restlessness, insomnia I took this medication at 9:30pm last night and haven't stopped vomiting every couple hours... I will never take it again! F 27 1 days
12/30/2016

 5  HSV2 Non that I notice, just very happy with drug Not a word of a lie.I contracted HSV2 at 20 years old.Started talking Val at 40. At 42 I battled stage IV lung cancer and lung mets to the brain, without Val I doubt I would have kept trying. I have had 5 major surgeries and 2 weeks of whole brain Radiation. Before Val I use to get out breaks once a month and sometimes even more frequently.Now I have not had an OB for years. I just turned 58. With all that pain and stress I do not think I could have kept fighting the cancer if I had to fight out breaks too. Antiviral saved my life. M 58 18 years
500mg 1X D
12/9/2016

 3  Genital Herpes Outbreak in genital and anal area Diagnosed with genital herpes in my early 20s. No outbreaks until I had my first child at 36, then mild itching over the next 2 years. It was manageable but annoying. My doctor put me on suppressive therapy at 500 mg daily. After 3 days I had the worst outbreak ever. Lesions on genital and anal area, red bumps on my buttocks, arms and underarms. I stopped taking it a week later. Two weeks into the outbreak and the itching was unbearable. I started taking the Valtrex again but upped my dose to 1000 mg a day. After 2 days, the sores are starting to slowly heal but the itching and weeping is still there. I wish I never started taking Valtrex because from what I've read, I will likely have full blown outbreaks if I stop. This outbreak was worse than my first. F 37 4 weeks
500mg
11/19/2016

 1  Cold sore Extreme nausea and vomiting, hot flashes, shaking, headache, extreme stomach cramping Started taking because of a cold sore and after first dose I started feeling nauseous but I thought it was due to taking it without food. So I tried again with food for my second dose and I still felt so sick. Had to call my doctor because I was considering going to the ER. Its now 2 days later and I've thrown up 3 times since stopping the medicine and I still feel extremely nauseous. Definitely not worth the long lasting side effects. F 18 1 days
2x 12 hour
9/18/2016

 1  Genital Herpes Devastating Depression Most horrible drug I have ever taken. Within a few day I started to experience extreme depression. When I stopped the drug the depression has lasted for years. While I have no proof it affects or causes long term depression, I am positive it was the cause of my initial depression. Please so not take this drug! M 61 5 days
1 g 1X D
7/25/2016

 1  Suspected Genital Herpes Started medication at 1230pm yesterday and wiithin two hours of first dose severe tingling/stinging started in exterior vaginal area (inner labia majora - the totality of the soft tissue burns/tingles/stings). After second dose last night the soft tissue inside my mouth had exactly the same symptoms and the symptoms in my genitals worsened significantly. Hershey's milk chocolate actually BURNED my mouth like it was a jalapeño.... I Havent eaten a single thing since --it's the next day, now. I will NOT be continuing this medication! I had zero herpes symptoms/diagnosis and went to doc yesterday for BV test which was positive. At that time the doc noticed a lesion and took a sample with a swab and it Hurt like hell. That was the only time I was aware it was there and the pain stopped immediately. I didn't start my Rx until 4 hours after the swab and had zero symptoms until two hours AFTER taking it.. During my research many people have denied Valtrex has this effect, I assure you, IT DOES! The blood work and swab results haven't come back yet but I'm giving the doc the benefit of the doubt. I have no idea which type I have (HSV1 or 2) or how long I've had it since I had lesions that didn't itch or hurt until she sampled it. My only symptoms were bacterial infection or yeast infection related. My husband has HSV1 so I suspect I got it from him. We have been together for 15 years. I will let this virus run its course naturally, I can barely sit down because the burning/stinging is SO SEVERE F 42 7 days
1000MG 2X D
4/29/2016

 2  Hsv2 Slight tingle in throat once I took the pill 30min in very slight cotton mouth ears seem stuffy 2 hours in upper body itching and mild headache pressure.. mild burn in abdominal area .....icy hot feeling in upper body head pressure still there some feelings subside now Extreme fatigue! I can't do this If it helps you with no side effects like headache or fatigue keep taking you are lucky I'm not ..........God speed! M 32 2 days
1gram
4/23/2016

 3  Herpes in the eye Nausea, feeling very tired not in great mood M 22 4 days
2X D
4/8/2016

 1  Shingles I have taken two 1 gram doses which has given me a severe headache. I have MS and occasionally have balance issues. This morning I almost feel down the stairs at a school in was teaching at. I have a headache now for six hours. I will not continue taking this medication. F 58 1 days
4/8/2016

 5  Hsv2 Can't sleep and some sharp stomach pain. I have only slept with six people in my entire life and the sixth person is my husband now of 22 years. Unfortunately I did not know what it was until after we had intercourse I did contract this to him and I will never forgive myself and I do not know how I got it so to everybody out there go celibate :( My poor husband he doesn't even look at me the same I don't think except he did stay with me but I can't help but thinking that it's because he doesn't think anybody will have him in his condition :( F 40 2 days
500 mg
3/30/2016

 3  Shingles On the 3rd day of Valtrex, I started having a vagina itch. It is very uncomfortable. The rashes from shingles are drying up but the itch is very unbearable. I will be done with Valtrex tomorrow. I hope the itch subsides. F 47 7 days
1 3X D
3/13/2016

 5  HSVI/II Periodic GI disruption. I am a healthcare practitioner and am writing to encourage patients to try Valtrex if recommended. It is a very safe and effective drug. Understand that replies to forums such as this are often only submitted by those who are dissatisfied. Most of the negative reactions I've read are those of the virus, not necessarily the drug. Find out for yourself! I have many patients who never knew suppression therapy existed for "cold sores," HSVI. It can be life changing! Though you can still infect others on suppression therapy, with Valtrex I have no outbreaks and my partner remains HSV free! Valacyclovir is a Godsend to most patients and could be for you too. F 49 10 years
1-3g daily
3/2/2016

 1  Herpes 2 Cleared up my outbreak (first and only one so far) but am having truly unbearable side effects. Bladder hurts so bad I can't walk and when I go to pee, which is a very urgent feeling, nothing comes out. Badly bloated - sooo thirsty, tired all day long, depressed, can't sleep through the night. Not taking last four pills - I can't take this anymore already have been to ED and I just got pain meds no explanation. F 47 7 days
1 gram
3/1/2016

 5  Herpes outbreak Disorientation, extremely tired, very sleepy, sore throat, chills, stuffy runny nose. This stuff works but I think it shouldn't be taken every day. It's just herpes and it is what it is. So take it when you need it. M 50 3 days
500 2xday
2/27/2016

 1  Shingles Shingles is much worse Severe stomach cramps, headaches M 58 10 months
500 MG
2/24/2016

 3  HSV Type 2 Extreme fatigue, loss of appetite, diarrhea, stomach ache. First outbreak and I felt flu-like symptoms before I started taking it so I'm not sure if it is the effects of the Valtrex or the virus. F 33 2 days
2xd
2/20/2016

 1  HSV2 suppression therapy No noticible side effect for first 30 days other than insomnia. In next 30 days experienced Insomnia, dizzyness, disoriented, sleepy all the tine, took hours to fully wake up in morning, couldnt stay awake all day, violent and angry nightmares, angry and agitated for no reason, rapid heart rate,tingling in legs,constantly felt dehydrated, sore throat, dry mouth, metallic taste in mouth. Stopped taking and slept great, woke up refreshed and no nightmares the first day. Other symptoms not as bad, but will probably take a few days to get medicine out of my system. May be ok for a couple days to treat an outbreak. Everyday dose was not safe. Central nervous side effects are listed on manufacturers documentation, but not on sheet from pharmacy. F 48 2 months
1/29/2016

 1  Type 1 First night I took it I had horrible nausea along with tingling all over my body. 3 weeks in and I can barely walk from all over joint and muscle pain. Have sever headaches with TMJ and depression. I'm in a constant fog and now having severe anxiety attacks during my sleep. I'm 2 days off the meds and fog has lifted but the rest of the symptoms are still around. I almost feel like my legs are paralyzed and won't move. This is bad bad stuff! F 40 3 weeks
500mgdaily
1/19/2016

 1  I was told 6mos ago I have need new Is makes things kinna better it's makes me sleepy. I dnt know if any othervthinks tht hace happened to me I'd because of it I'd like to think this wht the vpeo bkemid is it would be greagtvknothtim not really mentality . I have 2 beautiful children tht is need and they need me not a half she'll of a mother has anyone have it kind of side affect look me up on fb pease 42 5 months
12/14/2015

 2  Shingles Terrible anxiety!! Never had anxiety for absolutely no reason. It could be a bright sunny day and I feel like the world is ending. Calling my doctor on Monday to see what the alternative is. Stopped the shingles from spreading but the side effects weren't worth it! M 35 3 weeks
1000 mg
12/12/2015

 2  Herpesvirus on lip I took 1 Gram last night and 1 gram when I woke up this morning. Last night, pain all the way up my left arm. Today,, severe headache with TMJ pain. Took 800mg of Advil. Not getting rid of the headache. But the Valtrex did wipe out my cold sore quickly . I don't think the painful side effects are worth it though. Will try Lysine next time. F 43 1 days
1000mg
11/25/2015

 1  Cold sore within 1hr of taking 4 valtrex i had very bad side effect. It made my lower back hurt so bad i was crying on the floor can't even walk..Maybe its damaged my liver and kidney! F 34 1 days
11/7/2015

 4  Herp Racing heart rate and night sweats. Wake up drenched in sweat F 24 10 days
2000mg
10/17/2015

 4  Cold Sores nasty metallic taste, loss of appetite Worked wonders on my huge cold sore; however, the metallic taste was unbearable. It felt like I am licking a metal dumbbell non-stop. Needless to say, brushing my teeth, gum chewing and drinking water excessively didn't help at all. F 23 1 days
1000 2X D
10/9/2015

 2  Shingles Nausea, bloating, extreme fatigue, dizziness, weird dreams, occasional racing heart, very slow reaction, headaches, ear ache While it did help clear up the shingles, I am not taking any more of this medicine. I cannot function or concentrate at work or home. F 30 2 days
1g 3xd
10/7/2015

 4  Shingles Insomnia, after the second day my sleep pattern that I had been on for over two years was off. Couldn't fall asleep racing thoughts for hours them couldn't get up when I did fall asleep. It did speed up the shingles blisters healing process. They were completely scabbed over in a few days. M 42 9 days
1gram
9/28/2015

 1  Cold Sores Severe restlessness. It was like horrible restless legs syndrome but all over my body. Difficulty breathing, I felt like I had to keep moving to breath right. I sat in my bed and rocked for a long time just to breath. It was horrible. I was very moody. Had nightmares and in the morning I am usually about ready to pee myself but felt I couldn't pee. I finally did. I will never take again. Next day my body is sore and with my first cup of coffee the restlessness started again. F 52 1 days
2 GM 2X D
9/18/2015

 1  flat warts & weak immune system Severe headache, heart racing, jittery, yet lifeless, no-good feeling all over! Not 4 me F 40 1 days
1gram tablet
9/16/2015

 1  genital herpes I started taking Valtrex and then started feeling better in vagina but I don't feel good shaky and dizzy and nausea pain shooting in my left leg like nothing I ever experienced. Would recommend this med.we dont know how much damage is doing. F 45 10 days
9/13/2015

 1  Suppressive therapy for cold sores This an update to my original post on 12/30/13. All of my many symptoms resolved within approximately 1 month of discontinuing; however, I have permanent joint damage in my right foot, which still causes pain. About a year ago, I attempted taking a dose to clear a cold sore and the return of symptoms was immediate. I haven't taken them since and won't. I've found that, once my body no longer was dependent on this drug, my own natural immunity strengthened. It took a few months. Now, I take 1000 mg of Lysine twice daily. I just happened to think of updating my original post today. I hope it is helpful to someone and saves you the frightening experience I went through. F 43 2 years
8/16/2015

 5  Herpetic whitlow First time: anorexia, lethargic, felt like crap (but might have been symptoms of a bad outbreak) Second time: so far no side effects I don't want to jinx myself but I took this at my very first sign of an outbreak coming and no blisters pooped up yet. LOVE this stuff!! F 28 3 days
500mg 2x d
6/20/2015

 3  shingles I experienced swelling of my stomach after the 3rd pill on the first day. Awful stomach ache and terrible gas pains that were stuck in my stomach continued to get worse. Mild Nausea, diarrhea in the a.m. and constipation in the p.m. with an urgency to go, fatigue, muscle twitching which was mild after the first day. I made it through day 6 and only took one pill on day seven. Doc. told me to the just toss the final two pills. It has been 48 hours and the pain and gas is there but subsiding and I hope it continues to get better because these were awful side effects! The Valtrex did reduce the shingles outbreak significantly so I guess it did its job but not without creating another problem...Both my shingles pain and my rash were tolerable on the drug but my stomach was out of control! F 33 7 days
1GM 3X D
6/12/2015

 4  Cold sores I was very very sleepy. I slept for hours at a time I took the dosage twice since I still had some small postules the morning of day 2. 6 hours after my second course and the postules have began to dry and scab. Nothing better out there for cold sores F 27 2 days
2000
6/7/2015

 4  cold sore Joint pain in fingers and lower back. HORRIBLE NIGHTMARES. Dreamed wife was a zombie and attacking me. Kicked her in my sleep so hard i hurt my foot defending myself from her. Nightmare has been recurring 6-8 times a night.... Not cool. Took care of multiple cold sores in about 4 days Aside from the side effects i am happy with the performance M 46 10 days
1 gram 3xd
5/29/2015

 5  Shingles Very mild stomach discomfort for about an hour after taking each pill. Small shingles outbreak on my back (first for me) was almost gone after the first day on the drug, although I still have some numb patches. Nice side effect: By the end of day 2, my back acne was noticeably improved, and seems to be better every day. M 39 4 days
1 gram 3X D
4/27/2015

 4  HSV2 Never had side effects before. Always take one pill when I first start to feel funny like an OB coming on. Then another about 8 hours later then another 8 hours later. Those 3 usually nip it in the bud and prevent an OB from ever coming to fruition. This time however I started getting a spotty rash on my chest. It doesn't itch. Just very blotchy. Took one in PM 2 days ago and one in AM and one in PM yesterday (my usual 3) and both today and yesterday I woke up with these splotches. I don't recommend taking this or any other medication directly before bed. Other than that to prevent an OB it works really well. I just try to use it as a last resort and keep my immune system up so I don't let the virus in. Smoking is the number one OB causer for me as well as around the time of my period. Don't smoke around the time of your period or you're asking for it. Lots of sleep and vitamins and hopefully you won't have to take Valtrex at all. Last resort ONLY. F 26 4 years
500MG 1X O
4/9/2015

 5  HSV-2 None Works really well for occasional outbreaks; relief within an hour or so; I took it right away just one a day for two days and then symptoms gone. Is effective even a few years after it has expired (not recommending that but this is a med you might not need for a year or two and then you are glad you have some on hand when needed) F 50 1 days
500 mg
4/2/2015

 1  shingles I am experiencing cold chills and lower back pain,every now and then a few stomach cramps I have my heat on 79 degrees and still feel cold F 47 2 days
500
4/2/2015

 5  Cold sores None I used to have cold sore breakouts monthly. I have been taking this medication for 4 years now and I ONLY have a breakout when I forget to take the medication for over a month. F 28 4 years
500mg
3/29/2015

 3  infrequent cold sores Started taking for an infected cold sore. Side Effects experienced: Severe headaches, hot flashes/sweating, fatigue, increased heart rate/palpitations, dizziness, anxiety couldn't get enough to drink. I will try and find other alternatives the side effects aren't worth it. F 32 2 days
1gm
3/17/2015

 3  Shingles Lightheadedness, extreme fatigue, loss of appetite, headache. Made my hair feel very dry. It did help with shingles rash. Not sure it helped with nerve pain. F 59 7 days
I gram 3X D
3/15/2015

 3  HSV1 +2 chronic cause of Borrelia First I got yeast infection symptoms: ulcer in lip/mouth that won't heal, been there 4 weeks now. Then feeling like vomiting and lack of appetite. When falling asleep minor shaking inside my head: like small epilepsy seizure. (I never had anything like that before) F 40 4 weeks
1x500mg
3/2/2015

 4  shingles I was initially afraid of the potential side effects, but only feel a little light headed and tired. I hope not to have shingles again, but if I do, I won't hesitate to take Valtrex. F 59 7 days
1 gram
2/19/2015

 2  HSV2 Short term memory loss, HAIR LOSS, exhaustion, muscle/joint pain, vision blurred, sensitive to light & sound, no appetite, depressed, detached feeling, bad dreams, body odour, sweating, racing heart, tremors, dry mouth & oral thrush. Less outbreaks are not worth side effects equivalent to having Fibromyaligia, depression & the flu. F 32 3 months
500mg 1X D
2/15/2015

 1  Herpes simplex Head ache Nausea Not hungry Dizzy Crying Nausea Can't sleep Messes with my Trileptal Messes with my Trileptal F 47 1 days
2/8/2015

 4  HSV 2 dizziness, headache, cncentration This really works. I cut my pills in half helped with most negative effects and taken once at nighttime. I get bumps around period time and swollen neck so I tend to take 500 during these times. I dont break out as frequently nor do i notice them coming. Hot water/baths help a lot during a breakout a bump or two. no more wearing tight underwear for that seems to upset my area. F 25 5 months
250 MG 1X D
2/5/2015


History
 1  Hsv 1 I became severely depressed after 6 hours after the first dose. Then, I became suicidal and homicidal. The next day I didn't take any. I feel horrible. Headache, feel weak, depressed, and I feel like I have the flu.if I could rate it 0 stars I would F 29 1 days
1g
11/21/2014

 1  Genital herpes Severe headaches, nausea, dizziness, vomiting I was was told on Monday that I have herpes and was prescribed generic valtrex. I took one that night and one on Tuesday morning and have been nonfunctional since. I cannot stand light or any noise, I can feel my heart pounding in my head, and I have barely eaten because I can't keep anything down (thrown up twice with constant nausea). This is the worst headache I could ever imagine, and for awhile the pain was so bad that I was sure I was having an aneurism, and that just gives me anxiety. I skipped my Tuesday night dose and I will probably skip Wednesday morning. I plan on calling my doctor and hopefully trying something else, otherwise I might have have to just not finish the prescription because I cannot deal with these side effects, they have been much worse than my first break out. F 22 1 days
500mg 2X D
10/8/2014

 4  Hsv 2 I was recently diagnosed with hsv 1 & 2. Taking 500 mg twice a day. It has cleared up the sores and the pain has decreased. But I'm tired and in a fog most of the time. I will probably continue taking 500 mg twice for 5 more days then start taking one a day or when I feel an OB coming on. Don't think I can handle the side effects of feeling tired not being able to focus or concentrate. M 57 3 days
500 mg
9/22/2014

 4  beacause its gud My sister had genital herpes and has been cured with the herbal medication gotten from dr. Equity, he cures other diseases too herbal is a great medication. To hell with the government and their insane policy, he have a medication that is hundred percent assured to cure genital herpes and you don't need to spend so much money on anymore . I want you to contact dr equity on: Dr.equity@yahoo.com My family is now a brand new one, so stop your worries and go get your medication and set the family free of the deadly disease that hold no respect to family harmony. Thank you for reading my comment. F 27 2 days
10Mg
9/10/2014

 3  Shingles I had pain, tingling, numbness, several days before the rash appeared. I initially thought the symptoms were age-related because of a stressful situation, and thought I may have pulled a muscle. I went to the doctor's the second day after noticing the rash. Side Effects of the Valtrex: FATIGUE Headache (It was worse the first few days) Hotflashes and CHILLS Bloating and slight nausea The rash began to fade after the second day. Virus located on back of left arm, elbow and to wrist, side of hand, palm, both pointer and baby fingers, and back of hand. Physician confirmed Shingles, and said it was unusual to have a breakout in more than one place. (...along inside as well as outside of the arm). I still have a great deal of pain, but the rash is fading. Took Naproxen EC for pain x2 daily - Now only at bedtime Ranitidine x2 per day to lessen stomach upset with Naproxen F 54 7 days
500 MG 3X D
6/24/2014

 4  shingles Dizziness, hallucinations, sleeplessness,bloating, weight gain, hot flashes, sweats. F 45 7 days
5/27/2014

 5  Oral cold sore Bloating and gas. But the benefit far outweighs the side effect. Next time I will try using gas-x when I take it and in between doses. F 38 1 days
2grams BID
5/25/2014

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