There are 367 ratings for the drug: LOTREL in the Askapatient database.

The average rating for lotrel is 2.5.
Results are sorted by Gender with males listed first.    
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Key to ratings for lotrel:
5-Very Satisfied: this medicine cured me or helped me a great deal.
4-Satisfied: this medicine helped.
3-Somewhat Satisfied: this medicine helped somewhat.
2-Not Satisfied: this medicine did not work to my satisfaction.
1-Dissatisfied: I would not recommend taking this medicine.

                    
Page: 1  2 3 4    Results are sorted by Gender with males listed first.
Rating   Reason Side Effects Comments Sex Age Time Taken
and Dosage
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 5  high blood pressure I do not remember any side affects worth mentioning I started taking Lotrel 10/20 (4) years ago after a physical at work revealed HBP and I was told by the nurse to get medicated .. everything was fine until I retired & when I was going to have to pay for it myself, I decided to just quit taking it .. anyway I had been monitoring consistently, both at home & at work .. I was in the 120/60 range on the Lotrel .. when I quit it the BP started going up, sometimes 180/90 or even slightly higher, which is no big deal to me considering some of the propaganda you read nowadays saying high blood pressure may not be that bad after all .. anyway, I started getting these, what I call Ice pick headaches maybe a few time a week & lasting only a second or two, so decided to go back on Lotrel to see if the headaches subside .. just picked up a prescription today & will update progress in a month or two .. or M 68 2 years
1/29/2010
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 5  HBP None, Maybe because I am only 35, but geez some people are just weak or over-responsive to drugs I guess. Worked in lower BP from 135/85 to about 120/80. Not a huge change, but helped. M 35 4 years
10/20 1X D
5/13/2010

 5  HBP None. I read many negative comments about this drug. All I can say is that for me it dramatically lowered my BP. Before taking it BP was 150/95 after 134/74. Don't think that you will have every side effect that people here have had. If your DR orders it, give it a try and keep an open mind. The HBP is much worse. M 62 45 days
5/40 1X D
5/13/2010

 5  hbp none Had an aortic valve replaced[st judes] with an aortic root disection due to a 6.2 aneurism. The disected aneurism was replaced with a dacron sleeve.My BP needs to be low because of the aneurism. BP is 108/60...PR 58..I run a landscape business with no shortage of energy. Best BP medicine on the market. M 62 8 years
10/40 1X D
8/25/2010

 5  High blood pressure I was on Diovan and Altace but my blood pressure did not drop significantly. Been on Lotrel for about 3 weeks now. No side effects at all, and my blood pressure has gone from 150/110 to 124/82 or lower. M 51 3 weeks
11/3/2005

 5  high bp none M 53
10/20 1X D
3/8/2010

 5  HBP Felt a little tired for about 2 weeks. BP was at 190/127, started taking 5/10 dose, 30 days later BP was at 120/80, now 105/65 and holding steady. My (almost daily) headaches are gone. M 35 7 months
1/15/2008

 5  HBP The first week or so I was easily winded and short of breath, but that has subsided and I don't have any problems now. Works great for me. I used Norvasc before which had little effect on my blood pressure. With Lotrel 5/10 I now run about 115/70 and am very happy. M 48 1 months
6/15/2006

 5  HBP The only side effect I've experienced is minor foot swelling. However it is a lot less than when I was on Norvasc only. With Norvasc it was everything from the ankle down. With Lotrel just my toes mostly. Have the "hot foot" in general to the point that I can't wear my boots anymore. Toes so sensitive it's uncomfortable to trim my toe nails. No sexual side effects. Actually the vasodialator part works really well. :) It works and I'm staying with it. I've had the swollen foot side effects with every BP med I've taken. Lotrel is the least and my BP is under control. I like it. M 42 1.5 years
12/29/2006

 5  HBP Absolutely none. Have been taking it for over 3 years. My blood pressure problem was the low end. It was 100-110. Lotrel lowered it to 72-80. What many blood pressure patients don't understand and I don't care what a doctor tells you, caffiene raises your blood pressure as well as a poor diet (meaning don't skip meals, eat at normal intervals). Also if you have something like chronic back pain, like myself also adds to your blood pressure. You mix these with a stressful job and you are sure to get high blood pressure. Unfortunately, it's the good people who try to do an excellent job and care about their performance who this affects. If you don't care you don't have anything to worry about and you won't get high blood pressure. Continue taking, don't drink anything with caffiene, exercise, eat at normal intervals, do stretching exercises if you have back pain, talk with your boss and let him know your blood pressure problems. If he doesn't care go to Human Resources or Safety, they do. If all else fails tell your boss to kiss your ass, because my 2 year old daughter would rather me working at McDonalds than not having me around. M 45 3 years
1/27/2007
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 5  Hypertension none works well M 46 8 years
7/7/2005

 5  HBP NONE TE GREATEST BP MED EVER M 57 2 months
12/8/2006
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 5  hypertension Worked great for about 2 years then severe edema clicked in. Could not wear any shoes without laces. Dr. switched me to Diovan hct (80mg/12mg). BP went up and stayed that way for months. Called Dr. and he doubled the Rx to 160/25. Came down but still high (anywhere from 200-150/103-86). Will see Dr. to discuss alternatives. Seemed to work very well for a few years, then ????? M 65 3 years
1/7/2007
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 5  HBP Did not think any, until reading the postings. Have knee pain and wondering if this could be associated. I've been on Lotrel so long that I can't be sure the two are assoicated. Lotrel 5/20 lowers my BP from 160/90 to around 140/80. Regular (3-4 times per week) tread mill / occasional jogging has reduced it down to ~120/70. Suffered severe headaches for many years prior to finding I had HBP. After struggling on serveral different types found Lotrel, and think its working fine.. M 53 9 years
6/18/2006

 5  HBP BP is perfect, hard for me to get BP up while cardio gliding, seems like it stays at heart rate of 90, not enough even though I gasp for breath and sweat profusely, erections not as hard,wasnt a problem with HBP< now is, was on Lisinoprel for 2 years and BP always high, now taking HZCT diuretic in combo with Lotrel, cant seem to lose weight either, dont know if age or poor eating habits, or like I said cant get BP up to burn calories, I feel it was a life saver with my BP so high, now is low but at what cost? yes I would recommend it and talking to doctor regularly, take BP every day keeping a record of it, M 46 1 years
7/18/2006

 5  hbp I had a slight cough, but it has gone away. I was on Diovan. With it was tired,had blurry vision, slight dizzniess and had gained weight. So far on Lotrel, I have more energy, vision has cleared some and have been getting good night's sleep-with vivid dreams! Waiting to see if the weight loss comes into effect. M 52 9 days
7/25/2006

 5  high blood pressure love lotrel" there are no side affects M 54 5 months
3/27/2007

 5  Hypertension Slight drowsiness. My doctor prescribed Lisinopril first, then added Verapamil. These medications did not regulate my BP sufficiently. He then prescribed Lotrel 5/20, and it is working very well at regulating my BP at 120/80. Unmedicated, my BP averages about 180/120. M 46 1 years
10/9/2006

 5  Lotrel 5 mg I was taking Diovan 160 mg for 365 days with no improvement; my doctor will not change the medicine but kept on increasing it (From 80 Mg to 160 Mg. From once daily to twice daily) until I went to a cardiologist and he prescribed Lotrel 5 my only, it changed my life. I have more energy and productivity. My family doctor did not do any testing to determine the problem but the cardiologist performed an EKG, Ultra-Sound and Stress Test to ensure functionality and everything is perfect. M 37 365 days
11/21/2004
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 5  High Blood Pressue I was taking Diovan 160 mg for 365 days with no improvement; my doctor will not change the medicine but kept on increasing it (From 80 Mg to 160 Mg. From once daily to twice daily) until I went to a cardiologist and he prescribed Lotrel 5 my only, it changed my life. I have more energy and productivity. My family doctor did not do any testing to determine the problem but the cardiologist performed an EKG, Ultra-Sound and Stress Test to ensure functionality and everything is perfect. M 37 5 days
11/21/2004

 5  High Blood Pressue No major side-effect, but after taking Lotrel and eating I usually very drowsy. Lotrel has may blood pressure at or close to normal. My doctor just love it when I go in for my three month check and my blood pressure is great! M 39 2 years
10/19/2004

 5   M 57 3 years
10/1/2004

 5  hbp possibly a little sluggish in the beginning bp down from 160-170/85 to 124/65 M 68 90 days
8/10/2004

 5  hypertension No major side effects except a little insomnia here and there. I experienced a little grogginess at first, but subsided and able to carry on normal including cardio and weight training 3 to 4 times per week. My workouts are energetic and have notice a loss of about 15 pounds over the past 60 days since taking Lotrel, could be increased creatine (which seems a side effect) My BP was 150/125 before taking Lotrel,now seems to range anywhere from 135/95 to as low as 112/80. M 48 60 days
8/24/2004

 5  hbp none M 57 1 years
3/31/2004

 5  high blood pressure Possible fatigue M 64 2 years
8/14/2002

 5  HBP None I take Lotrel/Diovan and Ziac - BP is 130/90 - no side effects. I've been on Diovan and Ziac for over 4 years - been taking Lotrel for 2 weeks. ( And yes the plumbing works fine! ) M 45 14 days
4/25/2007

 5  HBP Little to no swelling in lower legs compared to norvasc. I notice a slight dry cough some days. Small sacrifice for taking my normal reading from 155/92 to 125/78. I reccomend to give it a try. M 32 45 days
4/25/2007

 5  high BP I would say that I have a rare dry cough but much better than when I was taking Lotensin. It does on excellent job of maintaining my BP. The cough is a well known side effect of all the ACE inhibitor drugs, and Lotrel is nowhere near the worse. Besides why would you just blindly do anything, after all it is YOUR health, take some responsabilty and learn about your condition the diffrent types of meds for it, and known side effects. There are now 4 classes of meds for HTN, one of which more than likely will work for you. Just remember not everyone is effected the same way with any med. Because someone else has problems does not mean that you will. I think that if your MD suggests a med at least give it a try, you can always stop taking it if you do run into problems. To those who are saying that this, or any other, med should be pulled from the market or other such silliness. For each of you there are several others that are taking this med with no difficulty what so ever, and it is M 55 12 months
6/14/2007
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 5  high blood pressure great drug - I'M HORNEY ALL THE TIME,THE WIFE LOVES IT !!! M 8 months
4/13/2007

 5  Essential hypertension Initially, minor dizziness when taken on empty stomach (Lotrel 10/20). When taken with food, dizziness diminished. After a couple of weeks, dizziness disappeared. No side effects since then. Hypertension is under control with most BP readings being low 120's to low 130's over low 70's to mid 80's), but attempts at reducing dose diminished control (despite losing weight, joining a gym and regular aerobic/weight lifting exercise). Had to resume the higher dose. Previous medications (beta blockers and diuretics) either alone or in combination did not mitigate hypertension (frequently BP readings were mid 140's over 100 to 110). Side effects with other medications were present (uneasiness, nervousness) of which most alarming was a heart rate which dropped into the high 40's, never seemed to exceed 60 bpm. M 43 2 years
6/30/2007
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 5  BPH None Greatest feeling as it has virtually eliminated daily headaches and I have had no evidence of repeat strokes. I now work out for an hour, 3x week and last BP reading was 95/54. M 61 4 years
12/22/2007
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 5  High Blood pressure I have experienced no side effects at all My BP was 160/90 it brought it down to 125/70 also the headaches I had from my high BP disappeared instantly..I feel great, I would recommend this for people to try M 41 1.5 years
2/20/2008
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 5  HBP None that I can really attribute to the drug. I am routinely 130 or 120/80 from a high of 165/110 so it is doing the job. I'm a generally upbeat person, but there may be something to the feelings of depression and lower sex drive. Also, genetically I would not be prone to hair loss yet my hair seems to be more brittle than in the past. M 37 2 years
2/24/2008

 5  Hypertension (High Blood Pressure) None. Keep in mind that this is only a one day sample thus far. I plan on documenting it's progress as the days go on. This in my opinion, will give people a realistic view of not only what occurs (if any side effects occur), but in the stages it/they may occur. I didn't have HBP until I suffered a fall from the second story balcony (landing head first onto concrete) in December of 2007. So far, I have taken one pill and within 30 minutes, my blood pressure decreased from 160/04 to a little less than 120/70. While some may see this as a negative (too much), I see it as a great start. I don't smoke, don't drink too often (one drink on occasion on a one occasion per three months average), don't drink coffee, very active, never been overweight, and I eat moderately in the middle (pretty balanced; not too bad, not too healthy). Over the last 24 hours, my blood pressure has stabilized at the normal level without any signs of side effects with the strange exception that my body aches have decreased and I no longer feel stressed as I have over the last four months on a constant. More to come...see you at the end of week one. M 45 1 days
4/9/2008
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 5  HBP Had some lower leg edema at first after sitting for fairly long periods, but this has abated about 90%. (NB, I walk quite a bit & am in generally good health; age 57.) Otherwise no side effects after about 2 1/2 years. Have had good results w/ this med but it is still very expensive even out of patent, at about $3 a pill. M 57 2 years
4/16/2008

 5  High Blood Pressure None BP was usually 150/90, and at times up to 185/120. After taking Lotrel 10/20 (purple capsule), BP dropped to 95/65. Medication was then changed to Lotrel 5/10 (yellow capsule), and BP now runs 110/75. That's better than my BP as a teenager. M 54 2 years
12/10/2008

 5  HTN None This medication is a combination of a Ca++ channel blocker and an ACE inhibitor. I have had no tiredness or lethargy. This medicine is known for having less of those type side effects.I do not doubt you, I am just surprised. Wow, I feel tired now. M 55 13 years
3/11/2009

 5  Hpertension None About 3 years ago, my BP became uncontrolled & frequently spiked to 200/110. I was prescribed Lotrel 5/20 & my BP stays right at 120/80. Lotrel is doing a great job of controlling my hpertension. M 47 3 years
7/6/2008

 5  Hypertension Did not face any notable side effects It should not be taken along with few drugs like Aspirin, Heparin and few other mentioned at https://www.internationaldrugmart.com/lotrel.html which will increase the intensity of side effects. M 50 3 years
4/9/2009

 5  Hypertension None I've been on the 5/20 dose for almost a year. Very healthy and active, although hypertension runs in the family so started taking Lotrel. Maintaining my BP level very well with no side effects. M 28 11 months
7/9/2009

 5  Hypertension No side effects. sex hasn't slowed at all and my wife is mad. Came off of Tarka 4/240 because it didn't lower my bp enough. Lotrel brought my bp down lower and the cost is much better. M 55 9 months
9/15/2009

 5  HTN only first week, nausea, dizzy and Lightheaded when standing up to quickly. After week mild general weakness, week 2, no general complaints now. All my symptoms are normal, and were expected. I went from a normal non active bp of 160ish/100ish, up to 180/120ish active. You have to remember going from a high BP like this to 120/70ish is a big change for your body to adapt to. There will be side effects for a short time, and they should eventually level out, if you don't feel these side effects, the drug is probably not working for you. How many years did you have HTN as the norm, vs how long have you experienced normal BP? 3-4 days vs 20-50 yrs plus?? Plus, ALL drugs have side effects. M 31 6 months
11/2/2009

 4  hypertension I had headaches Lotrel increases the side effects when taken with few drugs like aspirin and heparin. You can find the list of other drugs that interact with lotrel at International Drug Mart M 50 3 years
4/9/2009

 4  Stage 1 Hypertension None. I've read all the other posts but have had none of the symptoms described. The first drug I tried resulted in back spasms so bad I could barely move. I quit taking it after the first day and they persisted for 3 weeks. After 1 year on lotrel (5-20) I still experience no side effects and my BP is a constant 25-35pts lower M 42 1 years
4/20/2009

 4  HBP Terrible cough at first, lasted 3 months, now cough free. Just began to have dependent edema. That may mark the end of Lotrel for me. My BP is great! M 58 3 years
12/21/2008

 4  hbp none. BP lowered from 150/94 down to 135/80....libido is lower, but I blame that on my ex-wife. Overall very effective. I'm also a private pilot...Lotrel 10/20 is on the 'approved' list with the FAA. M 51 2 years
1/5/2009

 4  Toprol 10/20 caused depression, anxiety, cough, chest pains, pain in hip insomnia. Switched back to 5/10 hardly no side efects except for weakness at times. Some sleep interruption. Lowered bp from 170/96 to 135/80. M 56 60 days
3/26/2008
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 4  HBP Ankle swelling, coughing at first, anxiety (might be work related), hypotension with strenuous exercise. Taking 10/40. Stuff worked OK -- got BP down to 120/80 from 140/100. I feel OK generally, but excessive ankle swelling has my wife concerned. Also experienced same in hands once (during 9 mile hike). I also took a pill (first one) right before a 90 minute game of 3-on-3 full court B-Ball. I won't do that again. I could barely lift my arms over my head and felt really weird. BP was about 90/50 when I got home. I'm going to see if Doc can adjust something to minimize or eliminate swelling. M 43 2 months
8/20/2007

 4  High Blood Pressure Mild to severe cough which triggered bronchitis Lotrel worked fantastic for 2 years until I developed a mild cough. Treated the cough and a few months later it returned worse than before. My doctor took me off Lotrel and the cough cleared in 4 days. Unfortunately, the new BP medication did not work well and in 2 months I again returned to Lotrel 10/20mg. However, a severe cough developed in the first week and cleared the 3rd day after stopping Lotrel. I will not try it again. It worked great but my body just started rejecting the ACE inhibitor part. Now to find a new BP that does just as good! M 44 2 years
5/13/2005

 4  Hypertension Some dizziness. M 58 2 years
5/16/2005

 4  BP None at first then about a month into taking Lotrel started experiencing coughing spasms due to tickling in the throat getting progressively worse to the point of gagging. Will be looking to move to a different med, side effect to severe. M 48 60 days
1/21/2005

 4  HBP None Diet, excersise and Lotrel have all contributed to lower BP. M 52 1 years
2/13/2005
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 4  Hypertensive/High Blood pressure I’ve only experienced grogginess when waking up each morning; then again, I only get about 6.5 hrs sleep each night (my fault). If I take it on an empty stomach, I can feel the reaction of it the drug as it opens up into the stomach – sort of a ‘hungry’ feeling. I always listen to my Doctor. I was off this drug for about 2 years, and my pressure got back up to 140/95. I do not smoke or drink and I am very active in the gym 5 days per week, much cardio work in the gym and bike riding. All blood work performed on me is ‘super’ normal. I’m an ‘off season’ type of bodybuilder, so maybe it’s the extra 10 pounds I’m carrying? I have no clue. My parents have no heart disease, no diabetes; no nothing! I only eat junk food on weekends. Email me if anyone is fit-as-a-fiddle, yet have hypertension. Thanks. M 43 2 years
7/27/2005
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 4  High Blood Pressure Swelling of feet went away ofter a month or so on it.I get up 2 to 3 times a night to urinate. I do not have diabetes.Lowered B/P from 180/110 to 130/85 taking 10/20 mg. I feel calmer and have no anxiety attacks. I can tolerate the heat in the summer without feeling hot, sweaty or slowed down by the heat. I cannot tolerate the winter any more. Lotrel has made me chilly in the winter.Have better erections with it.. M 50 1 years
4/26/2005

 4  hypertension On Lotrel for about 2 months. Developing severe lower leg and knee pain. SO severe at time unable to walk.Also on corzide. BP is great though. M 48 2 months
4/28/2005

 4  Hypertension For the first three days I suffered from a debilitating headache - however, that was attributed to the change in BP, and it did subside completely. I am currently experiencing some muscle fatigue - we'll see if that's the Lotrel or not. Within one week, my BP dropped from 235/130 to 140/95. I am VERY satisfied with this drug thusfar. M 41 7 days
4/29/2005

 4  BP Angina for the first 10 days and increased urinary output after taking pill. lowered my BP M 58 20 days
12/18/2004

 4  HBP I posted earlier, a few days ago: I don't smoke, nor hang around anyone else that does. I have a drink maybe once every other month. My cardio is superb! The only high sodium foods I eat are pizza, pretzels, and soda, but only on weekends. My parents have no HBP history. M 43 2 years
7/28/2005
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 4  High BP Lower sex drive. Usual ED meds are not effective while useing Lotrel. Going to Boston Medical today for evaluation. Male 50 yrs, sex life is important. Anybody have optional suggestions? M 50 6 months
1/29/2007
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 4  High Blood Pressure Grogginess upon waking. I take 5/10 before bedtime. My libido is definitely lower. No coughing, only a slight occasional tickle when exercising. M 64 2 months
11/15/2006

 4  High blood pressure Sluggishness; muscle fatigue; numbness in hands when laying with hands on chest. Very pleased with drop in blood pressure to normal range. The lower blood pressure is well worth the side effects; but, I plan to ask doctor whether I should try another med. M 61 6 months
11/16/2005

 4  B/P none I went from 168/101 to 128/60 in 3 weeks the Lotrel 5/10 wasnt strong enough...it lowered initially but wore off by morning...the 5/20 lowers 24 hrs for me M 42 21 days
9/17/2005
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 4  high blood pressure None BP went from 200/120 to 160/84 in 8 days. Headachs are also gone. M 57
5/17/2006

 4  bp M 54
10 40 1X D
6/22/2010

 3  HBP Greatly helped my blood pressure, but has knocked my you know what in the dirt. Also found the need to take a 2-3 hour nap after work each day. Started having problems with kidney function ranging between could not urinate to urination frequently. Today is the last day that I will have taken this medicine - I am calling my doctor on Tuesday. M 46 40 days
5-40 1X D
7/4/2010

 3  High Blood Pressure This is my first day and I feel tired, depressed, and lathargic. I feel like I don't want to do anything but sleep. I know my BP is down, because I feel zoned out and mellow. If I don't shake this, I will not stay on it. BP was 130/90 with Enalapril, but surged to 150/101 in the evenings. Doctor put me on Lotrel. M 38 1 days
8/8/2006

 3  Hypertension Attacks of extreme drowsiness at some times of the day. My BP is in a good range with the 10/20 dose, close to 120/80 most of the time. Take it with a diuretic. My Dr. hasn't seen this drug make anyone drowsy before me. This makes him wonder what's going on, so he had some blood tests done. Don't have results yet. M 47 2 months
8/25/2005

 3  Essential Hypertension Dull ache in right leg; difficulty sleeping - which I attribute to the leg discomfort. Stopped taking Lotrel and the leg pain went away. Had deep sleep last night. M 46 14 days
8/21/2006

 3  high blood pressure dry cough, not severe; feet swelling, moderate to painful; sexual side effects, difficulty ejaculating. M 56 12 months
9/17/2005

 3  HBP Swollen ankles, dermatitis (darkened skin in a single blotch around feet/ankles and wrists), periodic dizziness (light-headedness), weight gain, ED. Have tried many BP drugs. I'm taking Lotrel with HCTZ and it works, BP lowered from 184/120 to 117/60, side effects stink but are manageable. Worst is swollen ankles (which can be lessened by remembering to move around) and ED (mild compared to other drugs but still no fun). Calcium channel blockers have always made me sick to my stomach but no problems with this. M 48 1 times
11/3/2006

 3  HBP Swollen ankles, dermatitis (darkened skin in a single blotch around feet/ankles and wrists), periodic dizziness (light-headedness), weight gain, ED. Have tried many BP drugs. I'm taking Lotrel with HCTZ and it works, BP lowered from 184/120 to 117/60, side effects stink but are manageable. Worst is swollen ankles (which can be lessened by remembering to move around) and ED (mild compared to other drugs but still no fun). Calcium channel blockers have always made me sick to my stomach but no problems with this. M 48 1 years
11/3/2006

 3  High Blood Pressure I noticed a dry cough within the first 2 days of taking Lotrel. have been on this medication for over 6 months and still have same nagging cough. Blood pressure has improved, but pulse remained in the 100's, now have started taking Lopressor which has done wonders. M 30 8 months
5/6/2005

 3  high blood pressure cramps in calf muscles, aching joints in hips and hands, aching lower back, headache, light headed this is on Lotrel 10/20 M 43 30 days
3/29/2005

 3  High Blood Pressure I have been on 10/20 Lotrel for a week or so. My eyes and sinuses are very dry, if this persists its too annoying to continue with the drug M 48 10 days
2/17/2005
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 3  high blood pressure cough, aching hands and legs, muscle cramps M 43 30 days
3/21/2005

 3  High Blood Pressure Some fatigue (sort of a It lowered my blood pressure - no problem. M 33 3 months
10/7/2003

 3  HTN Weakness in upper arms, especially the shoulders. An 'empty" sensation around the chest along with heaviness and fluttering heart sensation. Decrease in sensorum at times. Shortness of breath. The weakness in the shoulders feels like I had been doing push ups or carrying weights around, and this was just from the weight of my arms. The empty sensation in my chest made me feel tired at the same time experiencing a heavy sensation, racing heart, and flushing sensation that felt like a fever. These symptoms were exacerbated in the evening just walking around outside, some 8 hours after taking Lotrel 10/20. Decrease in sensorum included memory problems, a feeling of fullness or a band around ones head. My blood pressure was 182/122 without any symptoms. My doctor started me on Diovan which brought my blood pressure down to 160/108. I felt better with the Diovan, even though it did not lower my blood pressure to our treatment desire. However, the Lotrel can only get it down to 150/90 on most days, but the side effects make me feel really bad, espically the cough that makes me feel like I have pneumonia or something. My doctor then had me take Hyzaar 100/25 in the mornin M 42 2 months
7/22/2006

 3  High BP Severe muscle cramping in lower body.Palpitations and congestion.Ears plugged and overall ill feeling. Dr. increased dosage from 10 to 20's since BP bounced around all over the place.Seems to have lowered BP but constantly feel bad.Been athelete for entire life and train in gym 7 days a week.Keep good diet etc. Have never felt so bad. M 54 2 years
5/6/2004
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 3  High Blood pressure Dry cough has persisted since starting on Lotrel in August 2002. Did lower blood pressure to Doctor's satisfaction. M 56 5 months
1/5/2003
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 3  Hypertension Severe fatigue and headache for the first three days after starting and after dosage changes. Started on 5/10, went to 5/20 and am now on 10/20. Has brought my BP down to acceptable levels. M 39 2.5 years
8/5/2004

 3  hbp constant headaches, muscle cramps (neck and back) M 48 5 months
10/24/2004

 3  hbp constant headaches, muscle cramps (neck and back) M 48 5 months
10/24/2004

 3  hbp constant headaches, muscle cramps (neck and back) M 48 5 months
10/24/2004

 3  high blood pressure Sensitivity to sun, I burn very easily and am constantly fighting rashes and hives. M 60 2 years
6/11/2004

 3  High blood pressure None for the first three weeks, but then a dry cough developed. The cough is very annoying and comes 5 to 6 times a day and at night. No other side effects Worked well in dropping my blood pressure to 120/60. Never had any previous medication, but for several years could not control my bp until I started medication. M 59 4 months
6/14/2004

 3  hbp I recently switched from Norvasc to Lotrel and after reading the other comments here, now know why coincidentally (or not) the night cramps in my legs and dry coughs during the day began about the same time. I have not confirmed the connection but with all the comments here, it sounds like it. Even now, the slight cramps are happening during the day as well. This hbp is for the birds!! I have been VERY unsuccessful in finding a drug that will keep my bp near normal. M 48 2 months
6/5/2005

 3  hypertension Extreme hypo-tension immediately after mild exercise, such as biking/jogging. So bad that after a short ride this past weekend I collapsed in my driveway, too dizzy to stand and on the verge of blackout. After about 15 mins I was able to put my bike in the garage, but had to lay down again before attempting to get inside. Once inside, I took my blood pressure...108/61 hr-96. Considering my systolic averages 140-150 with this medicine, no wonder I almost blacked out. Have only experienced this since my doctor upped my dosage of lotrel. I have an appt tonight and will request we try something else. slight cough, nothing bothersome. Constipation M 31 6 weeks
8/7/2007

 3  HBP Muscle cramps in back and legs from the Norvasc portion. I know this because I had the same feeling with leg heavyness just walking a short distance when I tried plain Norvasc. Switched to plain Benazepril without the Norvasc and cramps went away. M 50 15 days
4/10/2007

 3  hbp swelling and rash around ankles, weight gain, sore legs,hips,arms, my mind seems to drift off at first the 10/20 took about 2 months to get swelling so was put on 5/20 and it was ok at least for the swelling but now it's getting bad , too. It also caused potassium level to be too high per blood test so you have to watch for that as that can be dangerous M 53 18 days
11/21/2007

 3  hypertension I just recently changed dosages from 10/20 to 5/40. "Negative" side effects include loss of libido, dizziness, loss of concentration (blew a red light yesterday...just not concentrating well; even though I don't use street drugs, I feel "stoned" sometimes), muscle weakness and cramps in the feet to thighs. It feels like my legs weigh 50 pounds more and it takes a lot of extra effort to move!I don't have the motivation to exercise and have gained 30 pounds in the time I have been on the medication. "Positive" side effects:I can sleep for 8 hours a night without awakening (even more on mornings I don't have to get up for work), unless I have an early morning leg or foot cramp. I also no longer have the headaches I used to have before I started the medication. I am guessing that I was heading for a stroke unless I started medications when I did. I also take atenolol 50mg daily. I wonder if the side effects might occur because I'm taking a combination of Lotrel plus atenolol. M 54 2 years
2/4/2009

 3  Yes Have been taking it for 4 days now after being on other BP meds. I'm experiencing insomnia. Same as I was when taking metroprolol. My Mom takes it and she has no side effects except for swelling in thew ankles. A little fatigued. If insomnia does not go away, I know I'll become depressed. I'll give it some time. M 57 4 days
5/25/2008

 3  high bp none none M 55 1 years
6/2/2008

 3  Blood pressue Lightheaded, dizzy, hard to concentrate, sensative to vision, upset stomach. I'm so glad I reviewed this site. Lotrel has worked in bringing my blood pressure down but I have felt for a long time that it was the medication that was making me feel this way. The strange part is that it comes and goes. I could go a few weeks with minor symptoms and then experience a rough period. My doctor kept saying that if it was the drug it would be a daily issue.I'm making an appointment to get me off this drug. The question is what medication doesn't have side effects??? I guess I'll keep trying until I find the right one. M 42 2 years
8/23/2008

 2  High Blood Pressure 5/10 Worked fine for awhile then started feeling weak no energy, some isnomnia and dreams. Generally felt terrible. Was on Toprol then Lotrel now on Lisinopril 20 mg and feeling much better. More energy and sleep much better. I hope this one works out. M 57 7 months
9/5/2008
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 2  Hypertension I have been on this drug for 4 years. At first I suffered a few reactions light headed and dizzy. They lowered y dose to 5/20 and that seemed to work. I developed ED which my doctor says is common with BP drugs. Tough luck. This year I developed Nervousness, anxiety, tremor in my lower lip, along with the ED. I read the side effects on the web and found all my problems listed as side effects of this drug. Not worth it, I made an appointment to see my PCP next week and I'm getting off this stuff. I have had itching and hair loss also but attributed it to getting older. Now I'm not so sure. I'm seeing several doctors to try and get rid of these problems so far no luck. M 64 4 years
8/28/2009

 2  high blood pressure I asked to be switched from lisinopril to lotrel because all of the recent published trial results. I've been on it only a week and I'll give it some more time. I can't exercise any more because I'm just too weak. I have lower back pain and a low grade headache and my blood pressure is higher than ever in the morning before I take my pill. I'm on a 2.5/10 dosage per day which is very low but I don't dare take more. M 76 6 days
8/10/2008
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 2   After having problems with other drugs i began to take lotrel about three months ago for three weeks everything was fine it brought my b/p down from 180/110 to 110/70 after three weeks i started to have terrible back pain upper and followed a week later by sharp terrible head pains. so i started taking the medication every other day which made the headachs better, but when speaking with my doctor he has suggested for me to take it each day. I now have terrible constipation, stomach painsaslight but sharp chest, from time to time and very red eyes. I have had an mri, ct scan, and several ekg tests since having these isues all of which have came back normal. i now have an appointment to see a stomach doctor and cardiologist. i will come back and update further as time progresses. This works very well on bringing b/p down but every drug can't be for every one. M 31 3 months
4/27/2008

 2  Blood Pressure Palpitations--somewhat severe with pounding heart beats. Stomach upset and inability to sleep at night. Fatigue. I am going to ask my doctor to put me on something else as I can not handle the heart effects. I thought I was going to have a heart attack today from the way my heart was jumping around. M 58 5 months
4/1/2009
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 2  high blood pressure I have been taking this drug for so long, I have almost forgotten what life is like without it. I have suffered from a mild depression for years and I have always wondered what was causing it. I am convinced that this drug is a "fly in the ointment" if not the direct cause. I would encourage all of you who use this drug to be very careful and mindful of all of your symptoms. M 65 20 years
6/25/2008


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