WELLBUTRIN SR Reviews (BUPROPION HYDROCHLORIDE)

Average Rating: 3.5 (997 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

WELLBUTRIN SR  (BUPROPION HYDROCHLORIDE):  This medication is used to treat depression. It can improve your mood and feelings of well-being. It may work by restoring the balance of certain natural substances (dopamine, norepinephrine) in the brain.   FDA Approval Date: 2002-06-14 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on WELLBUTRIN SR: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR WELLBUTRIN SRCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  binge eating, ocd muscle and joint aches, like speed feeling. I loved it because I have been able to loose 40 lbs in 1 year. Haven't been able to get the scale to move in 15 years! F 49 365 days
5/22/2008
 4  Chronic Depression The first 3 weeks were awful. Major dry mouth, insomnia, and so much anxiety that I didn't even think about being depressed. Also have lost about 22 lbs which is a good thing. I stuck it out and almost all of the side effects went away. I still don't feel compelled to eat but I'm fine with that. Biggest difference is that I now feel hopeful not hopeless. Best advice is to stay on the meds for at least 2 months-it gets much better! F 49 4 months
2/3/2009
 3   Been on this drug since 21 December when I realized I was suffering (another)bout of major depression. Started at 100mg for 3 days then up to 200mgs. I have now been on 300mgs for about 4 or 5 days. Ruminating thoughts are awful - I have faith this will kick in soon. If I didn't, I don't know if I could handle all the side effects such as increased anxiety and insomnia. I hope I can update soon and say "Wow, it finally kicked in!" But as of today, I am still an emotional mess. M 49 24 days
1/14/2009
 3  depression always too warm, heart racing in the night. I have no change in weight....darn, would be a plus to this!! I think I am stopping . I dont like the insomnia. I am so glad to see that others are having some of the same problems with this drug. I only take 100mg 2x daily and did not think it could be the reason for the heart palpitations. I even went to my Dr and he did an EKG and never mentioned that it could be from this!! F 49 6 months
4/26/2002
 3  depression Felt somewhat better but had memory loss and that really bothered me. I was taking 150 mg. daily. F 49 2 months
7/31/2006
 2  depression/anxiety nervousness, short-temper, insomnia I started this as an add-on to prozac in an effort to reduce the sexual side effects of prozac. It helped only slightly. When I tried using wellbutrin alone, without the prozac, my depression returned. This drug, by itself, did not work for me, although it does give some benefit when taken with prozac. M 49 3 years
3/30/2007
 2  depression I have experienced nausea, body pain and tiredness. But the side effect that concerns me is the rage. I feel like i could kill someone and I am taking only 150 mg per day. The last week I have been crying a lot for any reason. I am taking small dosages of Alprazolan to cope with the anger and anxiety that I am feeling because Weebutrin. I have taken several antidepressants in my life , most of then SSRI and some have made me feel better like Cipramil or Effexor but they always have severe sexual side effects, like total anorgasmia.Those sexual side effects donīt happen with Wellbutrin. I will take Wellbutrin for another month and see what happens. Good luck for you all.Itīs tough but we have to go on. Just be aware of the anger and irritability because those side effects donīt show when the laboratory describe this medicine,and our kids and spouses may get hurt because of it. M 49 3 weeks
5/8/2007
Email
 2  Major Depression I feel a little bit of mild anxiety and a feeling of being sped up. I've been on Wellbutrin XL 450mg for almost 2 wks. It doesn't have any positive affect on my depression, yet. In fact my depression has worsened since I started. I want to sleep all the time and cannot do normal activities. When I started, my depression was mild. Now it's very severe. Before Wellbutrin, I was on lamictal, but had severe memory problems and quit. Has anyone else waited >2 weeks for this to kick-in? I thought it was fast-acting? Has anyone had problems with depression worsening w/ Wellbutrin? Thanks M 49 12 days
8/9/2007
Email
 1  depression Rage, vivid & disturbing dreams, anxiety. Over many years as a Registered Nurse, I've had many jobs. Good relationship with employers and coworkers except twice. Ten years ago took wellbutrin for one month & was fired due to the rage it caused. One year ago was fired a 2nd time after taking wellbutrin SR for 2 weeks, same story...uncharacteristic rage and hostility. If there's ever a class action for actual, real losses, I'm signing up. Why? Not because it causes rage and extreme irritability, but because no-where on the label, websites, or any associated literature do the side effects state rage as a possibility. I wonder how many precious children have been beaten, spouses abused, or other tangible violence or loss (like jobs), this med has caused. The manufacturer I believe, is trying to keep this quiet. F 49 4 weeks
8/16/2006
 5  depression None It has had a wonderful side effect: I GOT MY LIBIDO back! I was five years on Paxil and dead in that area. I can orgasm again, and actually I think better than before..I can often "come again" within five minutes of an initial orgasm, and often shortly after that again..I was never this orgasmic before! F 48 60 days
1/31/2007
 5  Depression/Anxiety WELLBUTRIN BENEFICIAL: Initially experienced some insomnia,racy/anxious feelings,confusion but these slowly past and rapidly diminished at the beginning of week 5. BE PATIENT, these type of drugs can take time to reset the brain chemistry. The Wellbutrin has minimal effect on Serotonin and primarily acts on Dopamine and Norepinephirine; in my case, this has worked. I am now in week 5 of using Wellbutrin (one week as a mono med) and I am finding it very effective in lifting mood and energy levels; plus,I have had an increase in concentration. As a number of other posters cautioned, it did take a full 4 weeks for the Wellbutrin to begin to achieve a good level of treatment effectiveness (and I certainly did want to throw the towel in a few times). My sincere thanks to everyone who shared their own experiences and emphasised the need to BE PATIENT and allow the drug time to level out the brain chemistry. As my anxiety seems to have improved with the Wellbutrin alone, I am now comfortable that, should I experience a serious anxiety increase, I can, per others experience and my discussions with my doctor, use Xanax to manage such a moment. My tip: If you are starting out on a new anti-depressant, copy and paste snippets of some of the postive med experiences you read about here and elsewhere. Print these words of encouragement out and post th M 48 5 weeks
11/15/2005
Email
 5  Bi-Polar II with depression Lightheaded, mild insomnia. Clear head, energy, improved libido. F 48 10 days
150 1X day
10/28/2010
 5  Depression Started at 100mg/day and worked up to 300mg/day (two 150mg tabs morning and night). The initial dose and each increase separated by weeks resulted in a "six expresso" caffine like event, couldn't sit still and lots of energy, which was OK. On going from 200 to 300 I had some tightness in the chest and a feeling that I couldn't catch my breath. These side effects went away after a couple of weeks at the higher dose. Increased sex drive. Persistant rining in the ears but not real loud. I've been on some other ADs and they had worse SEs. Nice to have sex drive. The ringing in the ears is the only persistant SE for me, and it is a willing trade for the regained desire to live and do things. If you are depressed and also lacking energy this may be a good choice. Some elevation of energy after 6 months of use but not much. I just feel much better. M 48 6 months
1/13/2009
 5  depression F 48 2 years
6/10/2002
 5  Depression and Anxiety The first 3 days were like how other describe as a mild acid trip. There was no sleeping. After that things normalized quickly until i did not even noticed i was on any meds except i was less depressed. The anxiety took a few years to get under control. I also get 30x0.5mg xanax a month to stop any panic attacks when they start. I have never needed to increase my benzo because i refuse to use them in a way that builds tolerance. I may go a few days without taking one then i will have an attack and may need 3 over the course of the day. I didnt think much about drinking on Wellbutrin because i didnt notice a difference. Then i have read horror stories about combining drinking and Wellbutrin. I do not have those or any other ill effects but i dont recommend it for others due to what i read M 48 1 days
300mg
3/5/2016
 4  Depression Worked pretty well except it kicked in hypomania sometimes because I'm bipolar II so we had to lower the dose. But unfortunately after a time, it made me lose 18 pounds and I was already very slim – 5'10" inches and size 6. I looked anorexic and I had to eat like a horse just to maintain my low weight. It was out of control. If you need to lose weight, I might be a great option for you. I love that it didn't suppress my sex drive . F 48 30 days
1X day
10/30/2015
 4  Stop Smoking Fogginess has decreased,dreams are still vivid Prescribed to double the dose after a week,twice a day, still smoking a few, but it's making it easier to put them down. I work in a bar that still allows smoking and I am noticing how bad they smell to me.So far so good. M 48 13 days
150 2X day
2/23/2011
Patient History
 4  Smoking cessation I did quit smoking. M 48
150 MG 1X day
9/7/2014
Email

Patient History
 3  depression Shaky hands in the morning & legs jerking while I am trying to sleep..I take this at 6pm with my Paxil..Don't know if need to change the time or see if it gets better.. Do feel happier. F 48 4 days
150mg 1X day
7/2/2013
Email
 3  clinical depression some anxiety, surface sleeping not a deep sleep, a sort of wired feeling It's hard to tell how this is gonna work since I just had hell withdrawing from Geodon and immediately starting wellbutrin 300mg. 150mg in the am and 150mg at lunchtime. I just want my life back. Hope this helps F 48 10 days
1/24/2006

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