WELLBUTRIN SR Reviews (BUPROPION HYDROCHLORIDE)

Average Rating: 3.5 (997 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

WELLBUTRIN SR  (BUPROPION HYDROCHLORIDE):  This medication is used to treat depression. It can improve your mood and feelings of well-being. It may work by restoring the balance of certain natural substances (dopamine, norepinephrine) in the brain.   FDA Approval Date: 2002-06-14 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on WELLBUTRIN SR: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR WELLBUTRIN SRCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3   F 44 60 days
4/10/2004
 3  depression weight loss (good thing), teeth grinding, jaw clenching, urinary hesitancy, dry mouth. When ititially starting it, increased depression, anger, thoughts of death Restarted several times and felt the same increase in depressive symptoms. Paxil worked much better for me, but the weight gain and 0 orgasms were enough to make me quit. Loved the weight loss. Somewhat effective for depression. I think I just need the serotonin effect, also. F 44 2 years
2/6/2004
 3  Depression and anxiety I have had a sore throat, itching (not bad), gas, feel like I am in a fog and feel like something is in my throat. I take 150 mg of Wellbutrin XL daily. I bump up to 300 mg on day 5 and couldn't stand the amount of medicine. I can't tell if it is working. F 44
9/30/2005
 3  Depression dizziness, nausea, headache I started taking 150 mg a day of Bupropion (generic) as I was weaning off of Effexor. The Effexor worked but made me gain weight. I did notice that for the first two weeks, I felt angry. I stopped taking for a few days and the anger went away. I started the Burpropion again two days ago and I have no anger, but I started with the headache. I am hoping it will go away as I think it is helping otherwise. I feel more upbeat and able to cope. F 44 21 days
1/9/2010
 2  Depression and Anxiety I was on Wellbutrin (regular dose) for 8 months. I pretty well felt like a zombie or an alien from another planet. It caused me to sleep more (my depression takes that form anyway, hence it was enhanced). It did not help my social anxiety. I didn't like it. F 44 8 months
11/2/2005
 2  Depression See my review of 2/12/2012 under 'Zyban' on this site. Exact same drug bupropion hydro but marketed under this name in Australia and UK. F 44 18 days
150 1X day
2/18/2012
 2  Depression See my review of 2/12/2012 under 'Zyban' on this site. Exact same drug bupropion hydro but marketed under this name in Australia and UK. F 44 18 days
150 1X day
2/18/2012
 1  Depression SEIZURE I started on Wellbutrin 150 1x a day for 6 days then increased to 150 2x a day. On the 4th day I had a grand mal seizure. Thank God my daughter was home. I had my keys in my hand to go to grocery store the next thing I knew there were paramedics standing over me. I hit my head, bit up my tongue, uriniated on myself and have to now under go multiple tests. I have no history of seizures. I've since stopped the medication. This is a scary drug and I would never recommend this. F 44 10 days
150 2x
9/27/2016
 1  depression anxiety loss of appetite. low labito, still depressed. anxiety is worse than before insomnia is worse than ever this drug is not for me M 44 1 months
2/14/2005
 5  Depression None When I started taking Wellbutrin SR I was depressed to the point of being suicidal. On the sixth or seventh day of Wellbutrin the drug kicked in and I just couldn't stop smiling. It's hard to be suicidal when you're smiling. After a day or two, the euphoria went away and so did the depression. It's over two years later and no depression. M 43 2 times
4/22/2005
 5  Double Depression After taking 300 mg for 2 1/2 years all of a sudden I started not being able to stay awake. Initially they thought I was suffering from a sleep disorder; however, when I started to take the Wellbutrin SR in a single dose instead of splitting the doses I became a new woman. Like others I have found my sex life greatly improved. It's good to enjoy life again!!! F 43 3 years
3/7/2005
 5  Depression For the first 17 days I experienced light headedness, MAJOR sleep disruptions, racing thoughts, headaches, muscle spasms, bad taste in my mouth. I was also tired all the time, still as insecure as ever, and to top it all off - grumpy. I was taking Novo-Bupropion SR, 150 MG twice a day, 8 hours apart, 7:30 am and 3:30 pm. On my 2nd appt with my dr. at 17 days of being on this dosage, I told her my symptoms. She recommended only taking 150 mg in the morning. I took her suggestion and have been feeling great ever since. My libido has increased incredibly (better than ever maybe), I feel good enough to start exercising again, and to start doing good things for myself (improving myself spiritually and emotionally). Much better than the Celexa I was on previously. Maybe part of the problem in the first 17 days was that my dr. took me off Celexa cold turkey to put me on Wellburtrin. I'm now able to live in the moment, leaving stressful situations at work. I don't come down on myself so hard for mistakes I make. F 43 5 weeks
5/7/2006
 4  quit smoking Craving for cigarettes completely gone... In fact the sight or smell of them makes me irritable. No other changes other then I feel depressed the day after taking alcohol. Am going to stop that too. I don't want to start having the side effects others have experienced since I am very happy about the cessation of smoking. M 43 21 days
150 mg 2X day
4/18/2010
Email
 4  Bi-Polar II Increase energy during initial titration. At 300 mg (or as the dose approaches 300 mg from 200 mg), I hear voices. At 400 mg, I went into full-blown mania with memory loss (I did not remember what I did in mania, whereas past episodes I remembered). 200 mg seems to be the mainstay for my extremely drug sensitive body. Approaching higher doses to 400 mg gets increasing variations of the above side effects. M 43 2.5 years
200 mg 1X day
6/27/2010
Email
 4  depression Side effects dry mouth for 2/3 weeks. Vivid dreams . Loss of appetite. Decreased appetitite for alcohol. Tired but maybe that because I am not sleeping as well as I thought I was due to intense dreams? I seem to be able to focus better on any single project. Feel spaced out but sinus' are not doing well the past 2 weeks so maybe it's that. I definitely feel different but in a very unfamiliar way. I am not sure if I can say my depression is gone but I am functioning, getting things done. F 43 26 days
2/27/2006
 4  Depression Dizzy, tinnitus (ears ringing), grinding teeth, joint pain Wellbutrin XL - Data base wouldn't allow the entry. It has been fantastic for the depression. I'm going to stick with it, some have said that these symptoms subside. The joint pain (Elbows) has subsided in the past three days. Damn though I can put up with these symptoms a lot more than the depression. I'm starting to feel human again. M 43 14 days
12/29/2004
 4  moderate depression, anxiety Nausea and insomnia during the 1st week only. Ringing in my ears - I'm starting to notice it more often as the days go by. The last couple of days I've had a constant, low-grade headache. Lack of appetite - have lost 4 pounds I didn't really notice any changes and kept waiting for it to 'kick in'. Then about the 10th day I realized that the background chatter in my head had settled down, and my thoughts were less negative and more....normal. And I'm less prone to anger at minor things. So, is it the medication? I believe so! F 43 16 days
2/15/2007
Email
 4  Depression Didn't need as much sleep, insomnia if I took it near bedtime. More energy and ambition, mild "butterflies" feeling in pit of stomach Took generic buproprion SR, 100 mg in morning, 50 mg in early afternoon. Helped me deal with longstanding but low-level, almost subclinical, depression. Started it when going through a super-nasty divorce where I was the target. It helped me have the drive and energy to not just function in my very demanding job, but to excel in it. Gradually the benefits seemed to wear off, and after about 18 months I didn't notice any effects one way or the other. At 24 months I stopped cold turkey. No side effects for me when quitting; your mileage may vary. Great thing about Wellbutrin/Buproprion is that there were NO sexual side effects for me, like with SSRI's. One long weekend my fiance and I were intimate over a dozen times, though I had some male help from Cialis on that one. I took my Wellbutrin in morning and afternoon, because if I took it in the evening I would have trouble getting to sleep. M 43 2 years
6/26/2007
Email
 4  Depression Bad taste in mouth, anger, insomnia, energy, weight lose, shakes, depression worsened Week1-bad taste in mouth began, had tremors and shakes the first 3 days only, couldn't sleep more than 2-4 hours a night (I usually sleep 7-8), and I noticed a wanting to distance myself from others (took all I had to go to work around other people) week2-bad taste still there, Extreme/irrational anger bordering on rage, sleeping better/more, withdrew from friends and family (only left my house for work and only talked when I needed to). Doc had told me to give it at least a month, maybe 6 weeks. At the end of week 2, I woke up one day feeling a little bit more like normal me....and the anger was gone. The next day was so much better! The only side effect now is the bad taste in my mouth. Food doesn't taste bad, just my mouth. OH! And weight lose. Been on celexa for years with about 40lbs weight gain and inability to lose no matter how hard I worked at it. Now I'm down 16 lbs!! Weight lose was a lot the first few days and has leveled off to a lb every few days. I really thought I was going to have to quit it after the first two weeks. I'm really glad I stuck it out. I feel normal again. F 43 18 days
1/24/2010
Email
 3  Anxiety Increased energy, immediate weight loss, increased moodiness and short-temperedness I began taking this a couple of years ago, and took it for approx 1 year. Within days I noticed a marked increase in energy, and the weight (from 8+ years on Prozac), just melted off. I was ecstatic, and easily kept up the exercise as I had all those years of pushing myself. Unfortunately, though I didn't notice this as the cause, my mood had also changed considerably. I lost my temper very easily with my daughter, and our fighting and tiffs occurred almost daily. I couldn't understand it, blaming it on other circumstances during that time. I got off of Wellbutrin, and things went back to normal (normal moods, control of temper, also weight came right back on). I tried it again more recently (about 6 months ago), and could feel the moodiness creeping back by the second week, so got off of it right away. Was on 150mg both times. Would love to try again, if only for the energy and weight loss, but worry about un-justified moodiness. Will speak to my doctor about halving the dosage. F 43 1 years
12/27/2009

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