WELLBUTRIN SR Reviews (BUPROPION HYDROCHLORIDE)

Average Rating: 3.5 (997 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

WELLBUTRIN SR  (BUPROPION HYDROCHLORIDE):  This medication is used to treat depression. It can improve your mood and feelings of well-being. It may work by restoring the balance of certain natural substances (dopamine, norepinephrine) in the brain.   FDA Approval Date: 2002-06-14 (Sources: U.S. Centers for Medicare Services, FDA)

  

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More on WELLBUTRIN SR: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR WELLBUTRIN SRCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  None Feeling like something is stuck in my throat, difficultly swallowing , muscle aches, frequent gagging. I don't think I am going to continue this medication. F 25 10 days
150 2X day
4/11/2022
 1  hypersomnia, binge eating None- neither positive or negative. But WB generics have long proven inadequate. Your query concerns Wellbutrin SR ($2000 month). You should ask about Buproprion and must ask reviewers to identify the actual maker (sandoz, Mylan, Slate Run) as they differ greatly. Otherwise you are comparing apples and oranges. Few can afford Wellbutrin and few are actually reviewing it here. This is irresponsible Generic brands continue to prove inadequate. FDA is unwilling to test generic time release or to enforce simple laws not respected by drug companies in India etc. F 68 45 days
300 mg 2X day
3/30/2021
 1  Major Depression Muscle/nerve pain, fever, intense sweating, hot and cold flashes. I am not on any other medication, taking this alone. I was prescribed Wellbutrin SR 100mg twice a day to start. First day was ok, felt some dizziness and relaxed, just wanted to lay down. 2nd day, started feeling muscle and nerve pain. Then came the slight fever flu symptoms towards the end of the day. 3rd day, felt like full blown flu. Had a lot of body aches and pain, sharp needle pin pain through random parts of the body, fever with a lot of sweating and intense hot/cold flashes. Unbearable, so I decided it wasn’t safe for me to continue and so I stopped. Next day, fever went away, still some sweating but felt much better. It was Saturday, so had to wait til Monday to call MD. Don’t think I will continue on it with those side effects. I’m very disappointed in this drug. I was so hopeful it would help me but instead gave me a very bad adverse reaction that I never felt before. All I can say now to those who wants to try this med is be cautious with it and take it with supervision in the first few days. F 40 3 days
100mg BID
9/29/2019
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 1  Depression SEIZURE I started on Wellbutrin 150 1x a day for 6 days then increased to 150 2x a day. On the 4th day I had a grand mal seizure. Thank God my daughter was home. I had my keys in my hand to go to grocery store the next thing I knew there were paramedics standing over me. I hit my head, bit up my tongue, uriniated on myself and have to now under go multiple tests. I have no history of seizures. I've since stopped the medication. This is a scary drug and I would never recommend this. F 44 10 days
150 2x
9/27/2016
 1  Bipolar depression Positive: increased sex drive Negative: increase in suicidal thoughts, increased negative thoughts, worse depression, crying, feeling disconnected from world, time distortion, stiff neck, vivid dreams. No effect on appetite, no effect on sleep after day 3. I really wanted this to work, and the first two or three days were promising - I felt slightly wired, more awake, no desire to rest during day, but was able to sleep at night. Depression remained about the same. During the second week (still on 150mg), I started to feel disconnected from everybody else. Depression got worse, with feelings of total worthlessness and hopelessness, and could not concentrate on anything, constantly distracted. On day 14 I doubled the dose to 150mg twice a day. Big mistake. Thought about suicide all the time, felt I was already dead, like a ghost. Time moved very slowly, every minute felt like an effort to live through. Also became scared of being left alone and asked my husband not to leave me alone for a minute (very unusual for me, I'm usually quite independent). Stopped medication yesterday and already feel a bit better. F 56 17 days
150 1X day
5/1/2016
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 1  Anxiety Depression After 18 -you can only put up to 10 on the drop down menu here- 18 years plus on wellbutrin sr and thinking all of the hell I was going through on a daily basis was ME and that this was helping me from being even worse- I stopped taking it because I had extensive dental surgery and found out how it felt to be "normal"..even happy... I was put on many SSRIs that did not work. Doctors targeted my depression which was caused by my horrible anxiety. I got stuck with this drug as it is not an ssri as we found out the hard way, I could not tolerate ssris. People with anxiety READ THIS. 1. Docs are told to rx benzos with wellbutrin because it CAUSES anxiety. 2. Wellbutrin is processed by the body and turned into an AMPHETAMINE!! I started out life as a productive member of society and was turned into a sleepless, anxiety-ridden zombie reliant on benzos to keep the effects of the wellbutrin in check. Up to 6 mg of ativan. It took my memory, my patience, my ability to sleep...everything. If you have anxiety do not even consider this med. It may work for depression, but exacerbates anxiety!! Please let my story help you. Docs never told me this during my many hospital stays, reg. pdoc visits etc. Even though I was in horrible pain from my dental surgery... my mind felt happiness I have not felt in over 20 years once off wellbutrin sr. If you need to taper, look up how. I didn't. I went back on it two times and that was two times more hell, nightmares and prayers to God that my body could make it through one more time...I had to be sure wellbutrin was the cause though. Also, get your hands on Dr. Claire Weekes books, tapes whatever and listen to them over and over. They will bring you some peace while you recover. She is an angel for people like us! Good luck! Contact me if you want. F 48 10 years
400 MG
10/23/2015
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 1  Bipolar, Cig Smoking No side effects, but this medication was pure crap! Might as well have taken a placebo. I didn't have any side effects at all but it didn't do a thing for me. My doc kept raising my dose, still didn't help, finally told her I refused to keep wasting money on her upping my dose for an ineffective med. I have bipolar and my docs insist I take an anti-depressant even though I am manic type bipolar, I don't have depression but they insist it will help ease anxiety. It was about as effective as a placebo. Also, I was told it'd help me quit smoking. Wrong. Went from smoking one pack of cigs every 4 days to smoking almost an entire pack per day. It made me feel like I wasn't getting nicotine at all, unacceptable to be running outside to smoke every 45 mins. F 29 42 days
50 1X day
5/6/2015
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 1  depression Terrible! Increased heart rate and blood pressure that is worse during and after any exertion. I really want this med to work for me but I'm not sure. It's Sunday so can't call my psychiatrist until tomorrow. But that will be the first thing I do. F 31 3 days
150
10/26/2014
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 1  Depression, anxiety Stomach pain, rapid weight gain F 34 1 months
150 mg 2xd
5/26/2014
 1  Depression-Quit Smoking Aid Weight gain, anger, binge eating, constipation, weird dreams It did help take the edge off smoking, but the other side effects were too much. Plus I thought I'd lose weight but gained it instead and couldn't go to the bathroom and felt full of you know what all day.... M 39 18 days
150mg 1X day
3/24/2014
Patient History
 1  Depression, bipolar In the beginning it worked well on the 3rd, I was increased to 450mg, had a Grand mal seizure, went to the er. Did all the tests EEG MRI ct scan. Everything came back normal. Neurologist thought it was the saphris, so my pdoc kept me on it lower to 150mg twice a day. 4months later 2nd grand mal seizure. This time not quite lucky last thing I remember, I was standing by kitchen top juicing (seizure happening here) then the next thing i remember in a extremely dream state, I was struggling with someone(my wife) trying to 'escape' to our front door. We struggled to door that's when I start to really come to and realize that person I was struggling with was my wife & she was repeating 'you had a seizure...' Over & over. I sat down in disbelief that it happen for a 2nd time. Went thru the same battery of tests everything was clear. Seizure could only been drug induced the neurologist said. When my pdoc say On a lower dose it is safe. I have no medical history of seizure nor tested positive for being epileptic. It's sad because this was the only drug that was working for me. But it's not worth the risk. It's 1 in every 1000 at low doses that's not a low. And the actual seizure that gets reported is way higher than that. So if you are on it or put on it watch your dosage closely. M 32 6 months
150mg 2x
9/21/2013
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 1  Depression I spent this one year trying to find out why my stomach hurt so bad. I went to various doctors. No one could find out what it was. HORRIBLE stomach pains. Every day. I told them all I was on Wellbutrin. They said no it wouldn't cause that but it did. I stopped taking it and got better. I "tried" taking it one day, several years later, because depression came back. Whattaya know, HORRIBLE stomach pain! Its not in your head. This drug is powerful and scary. It did not help with depression. F 37 1 years
1X day
6/1/2013
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 1  Depression, weight loss I wanted to quit Lexapro b/c I had gained 50 lbs, so I asked for Wellbutrin. Switching to Wellbutrin SR was a big mistake. It gave me severe headaches that wouldn't respond to OTC pain relievers, vertigo-like brain zaps, and sent my anxiety levels thru the roof. Also made me feel very mean and snappish. After reading more online, I discovered that many people do not recommend it if you suffer from anxiety. Apparently Lexapro was doing more for my anxiety issues than I had realized. After one week on it, I called my dr, who said to give it a few more days. I gave it another week, but I just couldn't tolerate it any more. F 34 2 weeks
150 2X day
5/20/2013
 1  Depression It weakened the effect of the Adderall the first day, 2nd day I couldn't feel the Adderall at all. 3rd day didn't feel the Adderall and became very nauseated and stayed nauseated for 2 1/2 days. Now I am feeling the Adderall work again since I'm not taking the Wellbutrin SR. F 31 3 days
100mg
4/23/2013
 1  Depression Rage, anger, some difficulty sleeping, vivid dreams Incredible long-lasting orgasms.....better alertness then Lexapro, able to function well on 3-4 hrs sleep. Didn't do much to stop hunger. M 43 14 days
125 1X day
7/17/2012
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 1  smoking cessation headache, insomnia, indigestion, blurred vision, ringing in ears,constipation, dry mouth, increased urination, nausea, dizziness, erectile dysfunction. I'll figure how to quit smoking without this stuff. Not worth it. M 65 4 days
150 mg 2X day
6/15/2012
 1  Depression 3 days after taking this drug I became very angry at everyone and everything. The reason I switch to this anti-depressant was because Prozac was causing me to lose interest in sex and I was extremely fatigued. After taking Wellbutrin, I'd rather be sexless and tired than horribly angry at everyone and everything. Doctor gave me a new antidepressant Viibryd. Supposedly has less side effects....we'll see (it's only been 1 day) F 41 7 days
150 MG 1X day
6/14/2012
 1  Depression Seizure (grand mal) I started off 100 mg daily for 3 days, 100mg 2x day for 3 days, 150 mg in a.m. and 100 mg in p.m. x 3days, 150 mg x 2 day....on the 5th day of 300 mg I had a grand mal seizure at 9pm. Luckily I wans't driving but on a dinner cruise. I bit the side of my tongue as well as urinated all over myself. My bf said it lasted about 40 seconds. My CT scan at hospital was normal. However I just had an EEG test yesterday and the neuro said it showed abnormalities on left side of brain. I have to go back in a couple of weeks to retake it as well as a MRI. I'm so scared of having another one! Anyone else out there this happen to? My last dosage was Saturday 12pm. Prior to wellbutrin I took effexor for a couple of weeks and I broke out with itchy bumps so I had to stop taking that. Prozac and Celexa didnt do anything for me. F 43 2 weeks
150 2X day
8/4/2011
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 1  Depression I ONLY took this medication for 5 days. On the first day I experienced dry mouth. On the second day anxiety. On the third day I started having major side effects such as TOXIC OVERLOAD (LIVER AND KIDNEY PAIN), HEADACHE, anxiety, chills, and head fog. I stopped it and detoxed my system with herbal tea, water fruit and veggies. I feel 100% better! My best advice is to stay far away from Wellbutrin SR and try XL instead! If XL doesn't work, stay far away from this medication period!!!!!!!!!! I only took this medication for 5 days. I had to discontinue use do to Toxic Overload and Migraine! I detoxed with herbal detox tea, water, fruit and vegetable smoothies, and now I feel 100% better! My advice is to try Wellbutrin XL, and if that doesn't work for you, stay far away from Wellbutrin SR!! F 30 5 days
150mg 1X day
1/28/2011
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 1  depression interstitial cystitis or chronic bladder inflammation I believe this medication caused chronic bladder inflamation. It damaged the lining of my bladder. It is called interstitial cystitis and it may be a permanent and painful condition. It feel like you have a urinary tract infection, but it could be permanent and progressive. Now many things irritate my bladder tht didn't before. I can no longer drink coffee or alcohol. It feels like I constantly have to urinate. I had no idea this drug could do this much damage. It just says "frequent urination" for side effects. It doesn't say it could be damaging your bladder. I got a generic from Sandoz labs. Not sure if that makes a difference or not. M 53 60 days
150 2X day
1/8/2011
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WELLBUTRIN SR  (BUPROPION HYDROCHLORIDE):  This medication is used to treat depression. It can improve your mood and feelings of well-being. It may work by restoring the balance of certain natural substances (dopamine, norepinephrine) in the brain.   FDA Approval Date: 2002-06-14 (Sources: U.S. Centers for Medicare Services, FDA)

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