GLUCOPHAGE Reviews (METFORMIN HYDROCHLORIDE)

Average Rating: 3.4 (586 Ratings)

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 Type: Rx Drug

  

GLUCOPHAGE  (METFORMIN HYDROCHLORIDE):  Metformin is used with a proper diet and exercise program and possibly with other medications to control high blood sugar. It is used in patients with type 2 diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke. Metformin works by helping to restore your body's proper response to the insulin you naturally produce. It also decreases the amount of sugar that your liver makes and that your stomach/intestines absorb.   FDA Approval Date: 1995-03-03 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Gender with females listed first (reviews with no gender reported listed before females).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on GLUCOPHAGE: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR GLUCOPHAGECOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Type 2 Had taken plain Metformin in past with very bad stomach issues. Now am taking Metformin HCL ER (extended release) with almost no issues. F 66 1 years
500 2X day
11/9/2015
 5  PCOS The only side effect I've had is diarrhea, only on the first day of taking it. I see so many horror stories about this medicine. If you do not want to get violently ill, you have to eat right! This medicine does not tolerate carbs, so every meal has to be limited to a small amount of good carbs (i.e no white carbs). If you eat something bad, it's going to come out in the form of horrible diarrhea and nausea. Take the pill in the middle of your meal to avoid side effects as well. My period arrived in the first 2 days of taking it, I've lost 4 pounds, and my face is clear. I feel much better already! F 28 5 days
500 2x/day
11/21/2016
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 4  Insulin Resistance & PCOS somewhat loose bowels, weight loss, decreased appetite I've struggled with PCOS for years and was recently diagnosed with Insulin Resistance. Started taking Metformin 4 days ago and have lost 5 pounds. I've had somewhat loose bowels, but no diarrhea. I've struggled to eat over 1000 calories in a day. I've lost all cravings for sweets and carbs :) F 28 4 days
1/23/2010
 4  Pcos insulin resistance Second day loose stools few days later fatigue. But OK after that taking it with vitamin b12 and a vegan multivitamin also went on Mediterranean and plant based diet exercising for hour and half a day. Was put on other brands of metformin that I cudnt tolerate then my local chemist recommended glucophage life saver. Diet control and exercise cudnt shift the pounds and menses came early. Glucophage made my period come around 27-28th day taking it with progesterone cream. F 42 7 days
750-1750 1X day
8/19/2023
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 4  PCOS I have been on this med once before and couldnt handle the diaherrea. Now back on started at 250m now up to 1500m a day. Had some diahrrea the first few weeks with nausea and stomache pain but now am doing better. Me and my Husband decided to do this to try for baby #2. I finally got my period after several months without. Now I am 10d post period and am having light spotting. Does anyone know what this could be from? I have never had this problem and am a little nervous. F 25 4 weeks
1/9/2010
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 4   Constipation, otherwise great Blood Glucose control, A1C 6, FBS 80-110. ONLY The GENERIC BRAND worked for me. I first started with the ROACHE brand for 4 weeks, it did NOTHING for my blood sugar. I switched to a generic brand made by another company and it worked perfectly, same dose, and has worked perfectly for 2 years. I take 500mg 3 times daily b/f meal. Wonderful. F 52 2 years
11/20/2009
 4  A1C was a little high/poss. PCOS I am wondering if anyone had these side effects as well: tiredness, hungry feeling (almost right before it's time to take another pill), & got a slight "period" earlier than normal even though I'm on the pill. Also, I "accidently" forgot I wasn't supposed to drink and had 2 beers while taking Metformin and I felt drunk so quickly and was hot in my face. I hope I can still drink eventually and this doesn't happen to me next time. (Even though I am not even a big drinker!) I am taking Metformin. Just started this week with 250/2x day, now 500 mgs/2x day. Will be going up to 1000mgs/2x day. Hoping this helps me to regulate my blood sugar and also lose weight (my "gut"). I am hoping this pill doesn't affect my birth control pill! I was TERRIFIED to start taking this because I am extremely scared of throwing up! But I've been "OK" so far. :) Since I have only been this for a week, it's hard to give this a rating. I give it a "4" for now. F 36 7 days
12/11/2009
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 4  Insulin Reistance Taking 1 x 500mg GLUCOPHAGE just before breakfast and again before dinner - no side effects. If I increased to 3 x 500mg or if I took it without food, the side effects were terrible stomach upset and loose bowels. Energy levels are more 'steady' and weight that was impossible to shift before is shifting (-15lbs in 36 days). I already had low carb diet and gymmed 6x a week - so transitioning to recommend program was not difficult. Only problem now is I've not had my usually regular period. Doc put me on HRT yesterday. I don't want to take it. F 46 36 days
11/7/2009
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 4  PCOS Stomach Pain, Fatigue, Aches My doctor told me that if you reduce eating fatty foods you will experience less gas and stomach pain. I have tried to do this and I think this is true. Ive noticed that when I eat less fatty foods, I have less stomach pain. That may help those who are having bad gas or stomach pain. Im on my second week of 500 mg and I am now taking it twice a day and next week I will take it 3 times daily. F 21 2 weeks
11/10/2009
 4  PCOS F 20 1 years
10/5/2009
 4  PCOS Stomach cramping, loss of appetite, light headed if I go too long without eating. 500 mg a day. Dr says that those symptoms with go away within 2-3 weeks. I have been on Glucophage for 5 days. I have already started a period after not having one for 2 months. F 29 5 days
9/21/2009
 4  PCOS I started taking 500gms once a day for a week, I had diarrhoea for most of the days. I then increased the dosage to 2 lots of 500gms a day. Still had the same diarrhoea problem with this but it was only in the mornings so it wasnt too bad. A week after that I increased the dosage to 3 tablets of 500gms a day. I straight away had quite bad abdominal pains, back ache and headaches. On the plus side tit seemed to bring back my periods which I havent had for 4 months. Which I think is why I had the abdominal pains. Overall as it has brought back my periods it is well worth taking if you can handle going to toilet few times a day. F 21 3 weeks
8/29/2009
 4  Insulin resistence-hypothyroidism Started 500mg 1x day for 2 wks increasing to 2000mg. was told to take it at dinner. threw up 4 nights a week. Split the dose taking 1000mg in am and 1000mg in eve. MUCH BETTER!!!! I don't care if it said XR. I couldn't live like that. Diarrhea and vomiting all the time. Now that that I split it, I just am sure to take it with food. Now I am constipated - lots. Can't win but... and this makes it worth it, I have lost 25 lbs in 3 months. It is just a question of managing the side effects. I have respect for how miserable it can make me if I abuse carbs. I also take lots of B vitamin supplements. Helps with mood swings, lethargy, depression, and malaise I was experiencing. I will continue to take it, just carefully. F 47 4 months
7/17/2009
 4  weight gain from anti-psychotics Diarrhea the second day. Occasional light headiness, some days super tired (fell asleep even after taking Adderall), just one mild headache, mouth tastes weird, more thirsty I take 500mg twice a day. Definitely take it with food or you are more likely to experience stomach issues. Don't go too long w/o eating or you get light headed. Overall, the side-effects have been mild and short lived. Like it so far (lost 3 lbs the first week) F 27 14 days
6/14/2009
 4  for my insuline resistance actually my side effects are unlike most of the other patients who are experiencing diarhea, am experiencing constant constipation! and very bad nausea and tiredness! F 33 30 days
6/10/2009
 4  PCOS and Infertility Dizziness, nausea, and muscle pain for the first month, soft stool thoughout entire time taking meformin, pain and acheness in upper back, and recently began noticing that I am losing hair (on my head) - now my hair is only about half as thick as it use to be. Does anyone know if hair will grow back after stopping medication? Other than the hair loss I can deal with all of the other side effects. I was really hoping that this med would work because my husband and I really want to have a child however I do not want to contiue taking it if I am going to loose all of my hair. F 27 3.5 months
6/11/2009
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 4  Insulin Resistance / PCOS terrible diarrhoea, nausea, lost all desire to eat, gas I have lost 11 pounds in about a week, I have cut my carb intake to under 75 grams a day and I also eat 25 grams of fiber a day. I can only eat lean meats or I get very ill. The thing I miss most is butter. But PCOS was dominating my life, well no more. I take 1000mg a day 1 500mg am with FOOD (and 10 mg fiber from food not supplament) and 1 500mg pm with food (and fiber from food not supplament). I have energy again. Stick with the med and know your limits as far a diet and you'll be amazed with the results. Eat the fat and sugar and pay later! F 28 2 weeks
5/4/2009
 4  Weightloss/PCOD No serious side effects, only a little diarrhea. I am only taking 500mg per day. I feel like I have more energy, also, I feel full very quickly and do not eat more than I need as a result. F 50 14 days
9/25/2008
 4  pre diabeties I have noticed i sweat tons more than before just runs off me. I feel a bit sick after i take it but, not bad I have been on it for 1 week 500 m a day first week than 1000 per day than it goes to 500 with each meal.Weight loss, about 1 pound a day.... F 39 1 weeks
7/28/2008
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 4  Insulin Resistance Initially I had a bit of diarrhea and cramps with the metalic taste but the doctor said to take it after a meal and no more problems and he also started me off on a low dose. What I have found though is I have become constipated and lots of hair loss which I never put down to the Glucophage...can it be? I have now started on Antagolin and wondered if it's okay to take with my meds...I'm on 1000mg twice a day. Is it safe to take on long term? F 46 5 years
8/14/2008

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