GLUCOPHAGE Reviews (METFORMIN HYDROCHLORIDE)

Average Rating: 3.4 (586 Ratings)

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 Type: Rx Drug

  

GLUCOPHAGE  (METFORMIN HYDROCHLORIDE):  Metformin is used with a proper diet and exercise program and possibly with other medications to control high blood sugar. It is used in patients with type 2 diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke. Metformin works by helping to restore your body's proper response to the insulin you naturally produce. It also decreases the amount of sugar that your liver makes and that your stomach/intestines absorb.   FDA Approval Date: 1995-03-03 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Gender with females listed first (reviews with no gender reported listed before females).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on GLUCOPHAGE: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR GLUCOPHAGECOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  insulin resistant really bad gas...and occasional diarrhea....other then that this pill is a miracle!!! where do i begin...after not having a period for 3 months i went to my doc for some blood work and found out i was insulin resistant so she prescribed metformin. i take 500 mg twice a day with meals...i have totally changed my eating habits and along with walking every other day i have lost 20 pounds in 3 months! and not to mention my periods are regular again. i have so much more energy...and it has also cleared my acne....its a miracle pill!!!!! F 22 3 months
3/27/2009
 5  PCOS Diarrhea Metformin has helped. Within 4 months my period came back (I am now on a regular 33 day cycle). However, periods are very heavy and experience a lot of cramping. Since starting Metformin 1 1/2 years ago I have lost 25 lbs (back to the weight & size I was 10 years ago!) I'm not sure if I will be able to conceive, as we haven't tried that step yet. First I wanted to see if my period would come back (and they have). I still have loose stools on a daily basis & if I eat anything fried will be on the toilet all morning (this is a small price to pay considering I have periods again & the weight loss is a plus) Metformin has worked for me & I expect to continue with this medication for many years. F 33 1.5 years
7/27/2008
 5  Impaired Glucose Intolerance Slight headache the first day. No other side effects so far. No problem with diarrhea or abdominal pain. Decreased appetite. I noticed that my appetite has decreased. I couldn't finish a sandwich. I have alot more energy. I didn't have to take a nap today. I had energy to exercise 30 minutes on the elliptical. I was able to keep up with my 7 year old son..usually he wears me out and I have to lay down. Now he is sleep and I am up. If appetite reduction and energy stay the same then I can see why so many people lose weight. I need to lose 40 lbs. I will post again with further results. F 41 2 days
9/27/2008
 5  pre diabetes sometimes a little acid stomach which is remedied by eating a small protein snack, nuts or something. Loose bowels once in awhile, no big deal. Smellier gas, but so what. My glucose readings have improved a great deal. I have lost no weight despite eating little and exercising regularly. But having better readings is great. So far haven't experienced hair thinning. Have been on it for about 6 weeks, 500mg extended release. F 63 6 weeks
5/1/2009
 5  Type II Diabetes Mild nausea starting dose was 500 and I also take synthroid for hypothroidism and between both health issues I was having difficulty losing any weight. I work out 3-5 times a week at a high intensity and nothing changed. Doc upped dosage to 2000 a day and so far so good, no side effects and I'm losing weight F 45 1 years
4/22/2009
 5  PCOS Gas, Gas, and more Gasssssss! Shooo WEEEEE! F 30 2 months
5/14/2009
 5  PCOS Bad GAS I like this drug, but I fart like crazy. Can anyone give some good advice about that. I'm a young lady, but I'm farting like a big brute! The smell is out of sight too! F 30 2 months
5/19/2009
 5  PCOS/Trying to Conceive I began the metformin about 5 weeks ago because I had been diagnosed with PCOS and clomid alone was not working for me. I struggled to get a period after stopping birth control in order to get pregnant. After about 6 months of trying to get pregnant (realistically it wasn't going to happen without a period) my doctor told me to go on metformin with clomid. I began the metformin about 5 weeks ago. I started out on 500 mg once a day, increased to 500 mg twice a day during week two, and 500 mg three times a day during week three and from there out. The first 3 weeks were rough... I had horrible diarhea many times a day and couldn't hardly take it. But I lost about 10 pounds in those weeks and my acne cleared. I have not had hairloss at all on my head like some others have reported. I have since found out that I am pregnant and that my levels are looking good so hopefully it can work for everyone else too. I totally 100% recommend it. If anyone has questions or concerns, feel free to email me! F 22 45 days
8/14/2009
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 5  insulin resistance F 54 90 days
8/27/2009
 5  Insulin resistance, PCOS Update of an update of an update - Metformin works wonder for me, even up to this day. Lost 23 pounds in all. Recommended! F 37 10 months
9/9/2009
 5  Weightloss PCOS diarrhea, heart burn, some stomach cramping, smelly gas I started Metformin on Monday 8/24/09 - 250mg twice a day, morning and evening. Medication to be taken with food. I need to lose 50 pounds and have been diagnosed with hypothyroidism, PCOS. I am 54 years old and have also had breast cancer, DCIS. I am hopeful that this medication will help regulate my PCOS. The first day I felt a bit strange, not dizzy but kind of not right if that makes sense. The second day I had diarrhea, not painful but had go GO NOW feeling. Today, I had 1/2 sandwich on wheat bread and made the mistake of putting a slice of cheese on my turkey sandwich. A few hours later I got stomach cramps and explosive diarrhea that lasted about 20 minutes and have had to visit the potty at least 4 times since then. Other than these episodes I'm doing fine. I see my doctor on September 7th for blood work. If all goes well, she will be increasing the dosage. I am not exercising right now but am pretty active. I'll keep everyone posted on my progress. I think cutting out carbs is the answer to this medication because I do feel much better if I've eaten a lot of veggies and protein. Would LOVE to hear from those who have lost a lot of weight with this drug, how long it took you and what type of diet you were on etc. Thanks so much!! F 54 6 days
8/29/2009
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 5  PCOS/TTC Stomach Cramps,Going to the bathroom often and urgently I love this med. and hate it! It's sometimes a pain literally, but it works. I have been ovulating more frequently, but still long cycles around 35 days. I am just now starting Clomid with this and hoping that works. F 30 3 months
10/23/2009
 5  insulin resistence Little or no side effects, until the fifth month of use. Joint pain, lower back pain on right side, and began spotting about a month ago. Lost 17 pounds with no effort, but am finding it back again and feel depressed. Back pain is of major concern right now and joint pain. I've suffered with pcos and panic disorder for most of my adult life. Metformin has seemed like a miracle until now. I've had such tremendous energy! I've felt some a wonderful sense of calm and could almost stop taking xanax.Also leg pain that was intense after standing is all but gone. But in the fifth month of use, I've developed joint pain and lower back pain, some leg pain and beginning to spot after no periods at all in over a year. And before that, a complete year. I've been reading about having a B 12 problem while on this drug and am concerned. I'm more than concerned...I'm worried now that maybe this drug has brought on another set of problems. Any feedback would be very helpful. Thanks! F 54 5 months
11/27/2009
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 5  PCOS/insulin resistance nausea, bloating, diarrhea I was originally put on metformin by a fertility specialist after being diagnosed with PCOS and insulin resistance. When I was trying to get pregnant, I stopped taking birth control pills and my PCOS symptoms increased dramatically. I have always been a fairly healthy person- I like healthy food and anjoy being active. But regardless, I was usually about 20-30 lbs overweight. Metformin gave me regular periods, more energy, a small waistline (size 12-size 6), and allowed me to have a beautiful healthy baby girl. I did have have some very uncomfotable symptoms at first, but I slowly increased my dose starting from one pill a day with dinner. The worst symptoms disappeared- UNLESS I WAS EATING UNHEALTHY. One of the ways metformin works is to prevent your body from absorbing all the sugar from starchy food. If you eat food with a high glycemic index, that food doesn't get digested by you- it sits in your GI tract and gets fermented by bacteria. Hence the blaoting and diarrhea. So if you have a lot of symptoms while taking metformin, it may be due to eating the food that is contributing to your condition to begin with. F 33 6 months
12/2/2009
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 5  Type 2 diabetes Initially cramping,gas(toxic. Could be used as a WMD)47lb weight loss. Nausea. Now on the time release..much better. Good drug. Weight loss is from really no appetite. Some days I eat like a pig..others just not interested. Overall I feel great and my numbers are good as well. F 54 6 months
12/16/2009
 5  weight loss nausua, but only after eating carbs. I craved carbs before, and my weight loss dr gave me this to try. I take 500mg at night and its slow release. This is just enough to curb my cravings, and I have dropped weight. Now when I see sweets, I don't really want them. Plus the carb related nausua helps me regulate eating so much of them. F 44 6 weeks
12/27/2009
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 5  PCOS diarrhea for the first two weeks that now is gone. tiredness that also went away. I lost 13 lbs on this drug without effort (from 127 to 114), my sugar cravings and binges simply went away. I still eat some candy, but I eat a couple pieces and that's enough where as before, since I was insulin resistent, I was craving sugar non stop. I also now have much more regular periods which is a blessing. I also see a decrease in my acne (actually don't need creams any more). This drug literally changed my life. F 29 6 months
1/11/2010
 5  insulin resistance I lost 60 lbs on it not even trying. Definitely curbs sweets cravings. Horrible explosive diarrhea with cramping tho. But overall makes my periods 100% regular and on time.. and I conceived. F 24 3 years
1500-2000
12/2/2013
 5  Trying to conceive / pcos I got pregnant! I was diagnost with PCOS about 15 years ago. I was using BCP and didn't have a period for about 10 yrs. Went off BCP to try to have a baby, and nothing happened for about 2 yrs. Doc put me on Met to help with ovulation and such. I had sporatic periods, and then just didn't monitor them. I went in for an exray and was asked if I possibly could be pregnant. I said "anything is possible". Nurse came in and told me I was! Turned out I was 3 months along :) That was 4 yrs ago, and our baby boy is 3 yrs old and healthy. If you have PCOS and trying to get pregnant with no success, try this med! I stopped it after finding out I was pregnant, and after I gave birth, my periods have slowly dissapeared again (which is fine with me!) F 35 4 months
500 3X day
12/21/2013
 5  PCOS and Insulin Resistance Metallic taste in mouth and mild nausea when taking with an empty stomach. I first started taking this medication when I was 16. I weighed in at 170lbs. The first week was icky but not unbearable. I had no bowel symptoms just a metallic taste and nausea when I took it on an empty stomach. Six months later on a low-carb diet (Allowing a Saturday splurge - though most cravings had vanished) and a 30minute work out once a week I was down to 125. Being a foolish teenager and considering myself cured I went off the medication only to regain the weight and fall into the same slump I had been at 16. 8 years later I'm back on the medication and aside from the metallic taste (Which I know will go away in about a week.) I'm feeling fabulous but mourning the fact I no longer care for chocolate! F 24 2 weeks
1/20/2010
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