GLUCOPHAGE Reviews (METFORMIN HYDROCHLORIDE)

Average Rating: 3.4 (586 Ratings)

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 Type: Rx Drug

  

GLUCOPHAGE  (METFORMIN HYDROCHLORIDE):  Metformin is used with a proper diet and exercise program and possibly with other medications to control high blood sugar. It is used in patients with type 2 diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke. Metformin works by helping to restore your body's proper response to the insulin you naturally produce. It also decreases the amount of sugar that your liver makes and that your stomach/intestines absorb.   FDA Approval Date: 1995-03-03 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Gender with females listed first (reviews with no gender reported listed before females).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on GLUCOPHAGE: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR GLUCOPHAGECOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  pcos definitely had upset stomach/diarrhea for the first two weeks, plus no appetite the first time i started taking glucophage i lost 29 pounds, which was a miracle, usually im like a compulsive eater but it made me have no appetite to the point that i COULDNT eat, i stopped taking it in college cause i couldnt drink on it and have gained atleast the thirty pounds back, i have no been on it again for a week and all the side effects are the same (so i hope the weight comes off again too!) F 22 1 weeks
7/6/2006
 5  PCOS No side effects at all!! Taking 1500mg metformin-XR in the morning with breakfast. I have had no diarhhea or stomach upset. I have been taking this since october 2006. I seem to have lost 5 pounds or so without even trying. I haven't altered my diet at all and I still eat lots of carbs but I hope to change that and increase weight loss. One thing I have noticed is that I am not as "groggy" in morning when I wake up. It used to take me at least an hour to feel awake in the morning, but now it only takes ten minutes or so. So far it has not totally regulated my periods but I did get pregnant the second month of taking it(ended in m/c though). It is hard to tell if it improved my cycle length since I have not gone through any complete cycles because of the pregnancy and miscarriage. F 37 4 months
2/18/2007
 5  PCOS none started taking it yesterday I was wondering if anyone had a low carb high protein diet they could email me. I am 19 yrs old and have had multiple miscarriages, so my doc finally after I went to another doctor and had some tests done prescribed me glucophage only 500 mg a day, I was also wondering any of you guys know the stats on having multiples while on this medication [email protected] Thanks F 19 1 days
3/13/2007
 5  PCOS Terribly constipation and constant naseau It worked! Never got my period because I got pregnant! No continuing to stay on until end of 1st trimester to help prevent gestational diabetes. Constipation and naseau could have been from pregnancy, I've heard that some women get those symptoms from moment of conception, and I sure had them until I was about 8 weeks along. F 24 3 months
3/6/2007
 5  PCOS I haven't had any bad side effects at all. No diarrhea or any stomach problems. I take 500mg 2x daily. I have lost 60 pounds this year, and I am FINALLY down to my weight in high school of 120. I'm graduating college this year and will finally be able to wear what everyone else wears my age. With this medicine my menstrual cycle started after an eight year lapse. It has really helped. I have taken it with Spironolactone (diuretic) for the past five months, and that is when I really noticed the weight fall off. No diet changes, only changed from Cherry Coke, to Cherry Coke Zero; one can a day. F 22 1 years
4/23/2007
 5  insulin resistant Gas and bloating the first couple of weeks but went away. I have been taking it for about 6 weeks and have lost 8 pounds. I have more energy and less of an appetite. F 35 6 weeks
2/26/2006
 5  PCOS/infertility Felt light headed, had some nausea and then a loose stool only the first day. Then switched to taking my dose at night before bed and my symptoms went away. I'm only on 1000mg once per day for my mild PCOS. However, it has significantly changed my life! I've lost 10 lbs in about 6 weeks, without changing my diet, and I was not even overweight to begin with. I'm less hungry and my digestion seems somehow better (less bloating/gas). Acne cleared up completely. My cycle seems to be perfectly regular as well now at 28 days. Before taking this drug I was in denial about having PCOS, but I am now convinced that I have it. Just waiting to see if I can get pregnant as well. I have hope again after 14 mos of trying to conceive. F 33 6 weeks
4/28/2006
 5  Insulin Resistance Syndrome After starting metformin, she did have the abd side effects on and off (abd pain, diarrhea) for about 2 weeks, then they decreased sharply. I am a mother of a 6 year old girl, who was 4'6" and weighed 111 pounds. Being a nurse, I noted that she started gaining weight awfully fast and eating constantly. I took her to a Pediatric Endocrinologist and after testing she was diagnosed with insulin resistance syndrome in May 2006. She started on 1000mg with breakfast and dinner. She is now on 500 mg twice a day and, 4"7" and 93 pounds, without any diet change. Her appetite was cut almost from dose one and she is a totally different child, energy for days and eats a serving of food and does not ask for seconds or thirds. This has been a blessing for us. F 35 6 months
11/18/2006
Email
 5  Type II Diabetes Gas, cramping first couple of weeks. Dizziness, muscle cramps and HAIR LOSS. Periods returned despite previously having an endometrial ablation. Take 500 mg twice a day. ACH1 was over 10, now 5.4. Have lost 64 lbs (90 total) since taking this drug, however, I am on a rigorous diet and exercise program. I don't think it is a "magical" weight loss drug. Hair problems could be due to the tremendous weight loss since this has happened before when I've lost weight, it just seems really excessive. The return of periods is disappointing, but it's nowhere near the severity of pre-ablation. Dealing with it since the good outweighs the bad at this point. F 44 5 months
11/18/2006
Email
 5  Weight loss, Pre diabeties The first day bad diarrhea! I've been very thirsty for water too. I've lost 5 pounds in 5 days! I'm very excited!! I feel like mentally it's easier to not over eat. I went from 334 to 329!! Hooray!! F 23 5 days
12/10/2006
Email
 5  insulin resistance and pcos gas, bloating and loose stools. I have been taking the generic form of Glucophage, Metformin for 6 days and already have lost 5 lbs. I am so excited about this drug. I was always a thin person, but started rapidly gaining weight in the last 4 yrs. I am 5'9 and 229lbs. Hope to lose about 75-85 lbs and get back to my old size. F 29 6 days
12/5/2006
Email
 5  PCOS nausea,gas,tired,felt like i was unbalanced I have lost 8 pounds and I'm starting to see less of a brake out on my face. Acne and My weight gain has trouble me for 3 years after the birth of my 3 child. If there are any websites for better communication I love to join! F 38 2 weeks
12/7/2006
Email
 5  PCOS Nausea I've been taking met for 3 weeks now. 500mg 1st week rising to 1500mg in the 3rd week. I got a period in the second week for the first time in nearly a year. I've also lost 8lbs. F 34 3 weeks
12/4/2006
 5  PCOS, Insulin Resistance nausea, diarrhea, lots of gas and burping! :-) They eventually went away, thankfully. I lost 40.5 pounds the first year. I've now been on 1.5 years. I tried to step down this year and began rapidly gaining weight again. I have now gone back up a dosage and my weight has seemed to stablize. In the final outcome I've now gone from taking 4 500mg tables per day to taking 3 500mg tablets per day. I am hoping that additional weight loss will make me healthy enough to step down further on the medications. I do a cardio workout 4 to 5 times per week. And, I've now added strength training three times per week through Curves for Women. F 47 1.5 years
7/7/2007
 5  pre-diabetes, lack of energy maybe some nausea at first.. still experience frequent constipation & the drug totally changed my bowel habits (sorry..eww) I'm using Metformin 500 (twice/day) in combination with Wellbutrin XL 300 (anti-depressant), and now I have much more energy, lost 15 pounds without changing food habits, now I've lost a total of 36 pounds with the drugs & food plan. I have more motivation, and I don't feel like I have to eat all day. Before Metformin, I'd graze on snacks because I felt tired all of the time.. not anymore! No more lazy couch potato days! F 27 1.5 times
7/9/2006
 5  pre-diabetes, lack of energy sorry.. I posted the previous comment.. I meant to put I've been taking Metformin 1.5 YEARS. F 27 1.5 years
7/9/2006
 5  Weight Loss/ Possible PCOS diarrhea, loose stool first 48 hours then stopped. Also experienced "sick back of throat feeling" someone else had on here-but I cannot be sure it was due to pill. Had no ill side effect until I had been on it for a week then I had neausea so bad I started thinking I was pregnant and had a test done! Came back negative and I find out this sickness is #1 side-effect of Metformin. BUT BOY DID I LOOSE WEIGHT! Naseua annoying, but not severe. 500 mg 20 minutes BEFORE lunch. ALSO, TAKING 1 500 MG OF UNSWEETENED VITAMIN C WITH PILL HELPS WITH NAUSEA. I believe the reason I experienced the nausea is because of the time I took this med. I was told 20 min before a meal and I would take it a few minutes before-having often forgot to take it. Also, my Dr. told me NOT TO EAT lrg. amounts of fruits, sugars, or carbs.Any unheathly food u eat will cause diarrhea,ie junk food or candy. LOST 10 LBS IN FIRST WEEK with no exercise. I believe this drug does it's job, you must do yours and make sure you eat properly and strickly adhere to medication directions. Severe hair loss and balding (as well as excessive hair-growth) is a sign of PCOS, so I would find it hard to believe this drug would cause balding. Great drug for weight loss and PCOS, but MUST BE FOLLOWED EXACTLY. Or your think your pregnant:P F 26 10 days
1/23/2007
 5  PCOS, Syndrome X, IR If taken WITHOUT a low GI diet that is high in sugar: headache, loose bowels, gas, bloating. If taken WITH a low GI/low sugar diet: minimal I have been keeping a journal of what I eat in order to minimize the side effects of this drug and track weight loss. I started on two 500 mg doses daily (breakfast and dinner) along with a good low glycemic index diet. Very unscientifically (admittedly) I have found that taking 2 tablespoons of benefiber (or other fiber suppliment) with the meal I eat after taking Glucophage nearly eliminates all symptoms. I know it is counterintuitive to take a fiber suppliment when fighting loose bowels, but fiber is a regulatory agent and may also form bulk that has (at least for me) mitigated the side-effects of the drug. I did find that when I ate a pint of ice cream there was nothing I could do to beat the side effects. I have lost 8 pounds in two weeks with a couple falls of the good diet wagon (I am worse on weekends). I hope it helps: take a fiber suppliment (powder more effective than pills--I reccommend benefiber because you don't taste it in foods) and stick to the low GI diet and you will F 32 2 weeks
1/29/2007
Email
 5  PCOS Some diarrhoea and nausea/vomiting first month or so (especially once I was up on 1500mg) and if I ate the wrong foods. Loss of appetite, metallic taste in mouth. I took met for 13months and lost 25kg (55lbs) in that time. I had more energy, less sugar cravings and I think hair growth slowed down too. I had previously done 11 rounds of clomid with no success. I got pregnant for the first time after 13 months on met. Continued taking it for the first 14wks to avoid miscarriage and now have a healthy alomost one year old baby boy! I have only just restarted met a week ago, I delayed starting it again because I am still breastfeeding but the Dr's have given me the go-ahead to start again since my son is only feeding 3 times a day now. I got pregnant again when my son was 8months (no meds, PCOS and breastfeeding!!) but unfortunately had a miscarriage at 8wks2days. I honestly believe it was because I wasn't on met. I have 10kgs (22lbs) of pregnancy weight to lose so I am hoping met will help me again this time! Happy to receive emails :) F 27 2 weeks
3/21/2007
Email
 5  PCOS PRO: clear skin, WEIGHT LOSS [ 25lbs and counting ], more energy, curbed appetite, regular periods. CON: slight diarreha. [ that is the only down fall] DEF go with this F 20 4 months
4/3/2007

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