GLUCOPHAGE Reviews (METFORMIN HYDROCHLORIDE)

Average Rating: 3.4 (586 Ratings)

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 Type: Rx Drug

  

GLUCOPHAGE  (METFORMIN HYDROCHLORIDE):  Metformin is used with a proper diet and exercise program and possibly with other medications to control high blood sugar. It is used in patients with type 2 diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke. Metformin works by helping to restore your body's proper response to the insulin you naturally produce. It also decreases the amount of sugar that your liver makes and that your stomach/intestines absorb.   FDA Approval Date: 1995-03-03 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Gender with females listed first (reviews with no gender reported listed before females).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on GLUCOPHAGE: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR GLUCOPHAGECOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  type 2 diabetes I am truly frustrated my doc just raised my dosage 3 days ago from 500mg 2x to 1000mg 2x a day wow!! The gas pains and diarrhea was awful the first couple of days. I have less of an appetite and my legs hurt a lot...joint soreness...i am grateful i am off of work for a week to adjust to this new dosage :( Hopefully it will further lower my glucose level I am not excited about shooting up insulin. Hopefully my body will adjust to this new dosage. F 38 9 months
4/12/2007
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 4  Pre-diabetes/TypeII-Dx in flux Loose stools; GI pain, gas & bloating; Fatigue Worked up to 1500 mg over 3 weeks. GI discomfort at first w/extreme fatigue upon each increase in dose. Added B12 vitamin & Citrical -seems to have helped w/energy level. BG levels have been great from the beginning. Decreased appetite. Worth sticking it out through adjustment period. F 33 4 weeks
7/27/2007
 4  PCOS, OBESITY, & ISULIN RESISTANCE Lots of loose stools, explosive diarrea at first, when you eat greasy food or high carbs or high sugar, you will feel like death... If you alter your diet, you feel better and look more beautiful... Skin is clearer ( *I Look Radiant...when I eat better and tough out the 1st part) ask your dr. about welchol or something like that for diarrea ( it helps me) only if you continue to avoid greasy foods... I get muscle weakness when I work out, and I have had an easier time, breaking pills in half and then gradually increasing dosages, I call my doc. to check in... and we adjust the doses based on how I'm feeling. A bit of weight loss. Need to lose 8- - 100 pounds... I'm on cafe mom... so look at PCOS support groups... I'm "wow_you_get_me"... or on myspace I am www.myspace.com/dontalkcrapaboutme (It was a weird time period I was much younger.) I love metformin's ability to minimize my worst hair and acne and cystic problems so far.... Being off of it made me realize, I have no energy and I am miserable even without it. F 24 1.5 months
8/14/2007
 4  PCOS / Trying To Conceive Diarrhea / Very Minor Dizziness On Occasion / More Energy Each Day I'm On It I currently taking 500mg twice a day, both with a meal (one around lunchtime and a second about six hours later with the evening meal). I only have a loose bowel or maybe one bout of diarrhea if I eat higher carb foods....but if I eat anything greasy (even two thin slices of pepperoni), I get the sudden bouts of diarrhea. I think there is a definite correspondence with oily / greasy foods and the diarrhea. I have been on it for five days now and have already lost about six pounds. I expect that that will probably slow down. The diarrhea is also decreasing now that I'm recognizing what I can and what I cannot eat. I will stick with it, in hopes of becomming pregnant. We have been trying to conceive since I was eighteen, and Clomid didn't work. So we're doing the Glucophage in addition to a double dosage of Clomid to see if that will help any. F 25 5 days
7/29/2007
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 4  Pcos, infertility When I first started taking Metformin 500mg it caused major GI tract issues for the first 2 days. As I have increased my dosage (now up to 1500mg per day) the GI issues have become much better. Just be careful about what you eat. Not too much food or too much fat. F 31 1 months
11/2/2007
 4  PCOS Diarrhea, Less Fatigue, Some weight loss Glucophage has given me hope that I might be able to conceive and has started making my periods regular again. I was sometimes going 6 months with no period. I have now had two 45 day cycles and my last cycle was 42 so I hope they keep getting shorter! My doctor tells me it will take a few months for me to regulate. I never thought I would be so happy to have a period! I have been on the drug for a few months now and have noticed that I don't experience those days when I just want to fall asleep...I have more energy now and I find myself plucking less hairs on my face. Although I haven't really changed my diet, I have lost a few pounds. I started out taking 500mg twice a day (after breakfast and after dinner) for two weeks. I am now taking 1000mg twice a day...so 2000mg. F 30 4 months
10/20/2007
 4  PCOS Nausea, Diarrhea, Fatigue I took over a year ago in hopes of getting pregnant. I got pregnant within a month, continued it into my first trimester and now have a healthy beautiful baby boy. Back on it to treat PCOS and having terrible diarrhea. I'm also on birth control at this time and needing to loose 20 lbs. I've dropped 2 lbs so far in only a week. F 34 7 days
5/26/2007
 4  PCOS/infertility diarrhea I took metformin four years ago and then again two years ago, resulting in two successful pregnancies after being unable to get pregnant. Now I am taking it again to help with insulin resistance and weight loss, but I am having a harder time with my body adjusting to the diarrhea. I had my gall bladder removed after my second pregnancy, and so I wonder if that has something to do with the bigger problem with diarrhea? F 36 3 weeks
6/26/2007
 4  Infertility / PCOS / High Insulin Weight Loss, Diarrhea, Higher Energy Levels I've been on this for 6 weeks at the 1000mg per day dosage (two pills with the evening meal). I get diarrhea or loose stools multiple times a day, but find that I feel better on days that that is happening. On days that I don't get the diarrhea, I feel pretty lousy. It's a very noticable difference. I've lost about 25lb in these past six weeks...no other changes in my life-so it has to be the medicine. I have a healthy appetite now....not eating constantly like I was before because I ACTUALLY FEEL FULL FOR THE FIRST TIME IN MY LIFE!!! I sometimes have to remind myself or force myself to eat, and even then, I eat a small amount and am good. Too soon to tell whether my periods are becoming more regular or not... F 25 6 weeks
9/8/2007
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 4  PCOS/trying to conceive Some headaches and diarrhea.Has eased tremendously since starting 5 months ago. I have been on Glucophage since June 1st. My period regulated to 35 day cycles.I added my first round of Clomid last month and I am now 6 weeks pregnant.My last post on this website was on 7/17/07. Again, if there are any questions,please feel free to email me. Good luck to all of you. F 34 5 months
11/20/2007
 4  PCOS/Insulin Resistant/pre-diabetic Nausea - to help decrease side effects, take AFTER a meal! If I do that, I don't have any side effects. My doctor slowly increased my dosage, which helped me deal with the side effects: I did 500mg 1x/day for 2 weeks, then 2x a day, I now up to 3x a day. I usually have nausea for a few days when I increase my dosage, but by the end of 2 weeks, I'm fine. I've lost almost ten pounds in the 6 weeks with NO diet changes on metformin/glucophage. My period hasn't come back yet, but I'm hoping that with continued weight loss, it will. F 38 6 weeks
12/30/2007
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 4  Insulin resistance/rising BG My mother and grandmother died of complications from Diabetes. When I was 40, I suddenly started gaining lots of weight -- over 100 pounds in 5 years -- all docs said "to lose weight" and that I was insulin resistant. I am now 57. Been holding off diabetes just barely as my BG has been climbing. I read about metformin and asked my GP to put me on it. Only taken for 12 days. 500 am; 500 pm. Sides are same as others -- lots of diarrhea. BG has gone from 120-130 in am to LESS THAN 110 already. No weight loss as yet, but I sure hope that this helps as I eat very well -- low carb, small portions -- but have not been able to lose weight in 20 years unless I do a complete fast. Primary thing, however, is to prevent diabetes, and I will be very happy if this does so and hopefully the side effects will lessen. F 57 12 days
4/6/2008
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 4  PCOS related Insulin Resistance pro: more energy, more focused, BG stable (last tolerance test was 212 after 1hr/ 74 3 hrs later) con: alternating diarrhea and constipation Reading the comments I see that I will have to keep a food diary to see what I'm eating that may cause the GI probs. I lost both my ovaries to cycsts (13 and 16 years ago) but since PCOS is not a problem with my ovaries but rather a metabolic disorder - I still have the impaired glucose tolerance. Lucky for me I had my girls at 18 and 21 - before my ovaries went into severe cyst formation. Both of them have PCOS... thank goodness they've got better solutions for them than ovary removal! F 39 21 days
3/10/2008
 4  pregnancy diarrhea, nausea, dizziness, hair growth, for some reason I have increased facial hair growth since I've started taking this...hope we get pregnant though so the stomach problems & hair growth are worth it...but I found that if I take pepto after I take my dose with the meal then my stomach doesn't bother me as much... F 24 8 days
5/10/2007
 4  IR and PCOS Upset stomach, loose stool, nausea So far the GI affects haven't been that bad. I mostly feel sick when I take WITH food or when I eat/drink something with alot of sugar in it. My appetite is almost non-existent but when I do force myself to eat my stomach hurts for hours afterward and I feel pretty nauseous. So far I've lost 5 pounds in 5 days but a good portion of that is likely water weight from taking Spironolactone too. F 32 5 days
3/4/2007
 4  Diabetes On it for about two years. Very loose bowels - often! But got better. Some stomach pain, then shooting diarrhea, but now only occasionally. Saw that some people said hair loss - I've had a lot of hair loss since I've been on it, but never associated it till now. Also, I've been experiencing muscle soreness in my legs for over a year and muscle weakness in general now. Could this be a side effect, and is any one else experiencing this? F 50 2 years
3/5/2007
 4  PCOS Diarrhea--bad at first, not so terrible now (only if I eat something high in fat); nausea and vomiting (at first); bloating; loss of appetite and WEIGHT LOSS! YEAH! So far, so good. Not sure the weight loss is caused directly by the Met or indirectly through the diarrhea it causes. I hope it's the former... and that I keep on losing weight ('cause I definitely need to). Dose is 850mg times 2, taken at bedtime each night. F 24 1 months
5/11/2005
 4  weight loss gas, diarrhea, insomnia Love it.Lost 3 lbs in one week.Have much more energy. F 46 8 days
4/20/2007
 4  DM 2 non insulin dependent none Great medication, has kept me in good control with A1C levels in the 6-7 range. F 42 10 months
2/4/2005
 4  PCOS/IR On the first day of increasing dosage I get GI upset, I sometimes have that metallic taste, the side effect that I am most pleased with is the decrease in hunger. Over all I am happy with my results, My menstrual cycle has returned to pretty much normal, and I have lost 25lbs. F 29 4 months
1/20/2002

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