GLUCOPHAGE Reviews (METFORMIN HYDROCHLORIDE)

Average Rating: 3.4 (586 Ratings)

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 Type: Rx Drug

  

GLUCOPHAGE  (METFORMIN HYDROCHLORIDE):  Metformin is used with a proper diet and exercise program and possibly with other medications to control high blood sugar. It is used in patients with type 2 diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke. Metformin works by helping to restore your body's proper response to the insulin you naturally produce. It also decreases the amount of sugar that your liver makes and that your stomach/intestines absorb.   FDA Approval Date: 1995-03-03 (Sources: U.S. Centers for Medicare Services, FDA)

  

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More on GLUCOPHAGE: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR GLUCOPHAGECOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Pre diabetic I started this medicine a few months ago because of A1c was 5.7. It made me tired and just not feel good. Dr said stop for 3 months and recheck labs. Felt better but decided to start again because afraid labs would be bad. I've taken it for about 3 weeks now and I an depressed foggy no energy and leg pain. Took my last one this morning. I will check with Dr to see if there's something else that doesn't cause this awful feeling. F 71 3 months
500 2X day
6/4/2023
 1  Type 2 Diabetes endometrial lining build-up, fatigue, weakness, depression, suicidal thoughts, emotional highs and lows very extreme. extreme anger and rage. Hair loss, skin itching, loss of taste. I was diagnosed 3 months ago with Type 2 diabetes. He immediately put me on Metformin. Told me there would be stomach effects but they would go away over time. They weren't too bad as long as I took with my first mouthful of food. My blood sugar NEVER came down over 3 month period (he wanted to move me to 1500 mg which he said was standard) instead I quit. I experienced depression, weakness, suicidal thoughts, and then started having problems with my period which my gyno said had nothing to do with this. Then I had to have a biopsy and tests because even though I wasn't having a period my endometrial lining was still building up. Turns out there are studies on this and papers written, but when I told my doctor this she dismissed it. This drug is horrible but the doctors keep pushing it!! F 40 3 months
500 2X day
9/16/2021
 1  diabetes Diarrhea even on low doses and burning in my abdomen, bloating and discomfort. Unable to leave home because of digestive problems. Also lowered my TSH values for thyroid maintenance. It did effectively lower my glucose and A1C but at what cost to my lifestyle. F 78 20 years
1000 mg 2X day
1/2/2021
Email
 1  Insulin resistance My symptoms while on Metformin included the following: Constant burning across my upper epigastric region, insomnia, severe left leg pain on the lateral upper and lower side of my calf and at times in my left thigh. I also had a horrible weakness in my legs. If I had been sitting at a restaurant in a booth, or in a chair for some time, I had trouble getting up. I felt like a 90-year-old woman (I’m a young 60-year old) when I got up to walk. Near depression and fogginess with lack of motivation to do anything. I had an appendicitis a year ago, and I often wonder if the Metformin caused the inflammation that set off my appendicitis. Now, I’ve only been off the Metformin for 2 days, and the fog has lifted, and I have no more pain in my left leg. The burning in my stomach is gone too. On Metformin I had no joy in my life. So glad I discovered what was causing my pain and lack of joy in my life. It’s like a cloud has been lifted now that I’m not taking Metformin, and F 60 2 years
500 2X day
1/27/2020
 1  High blood sugar Nausea vomiting with no warning gas pains Horrible drug. I took it for two years. Did nothing to lower blood glucose and I was always sick from it. Don’t take this crap!! M 62 2 years
1000
7/8/2018
 1  impaired glucose levels severe allergic reaction to this drug after 20 minutes Thank GOD I'm allergic to this drug, I've seen the vomiting and explosive diarrea it causes. The 'cure' is worse than the illness!!! F 56 1 days
500 1X day
9/24/2015
 1  Sugar Explosive diarrhea and or vomiting with NO warning. Often happened in public. I got off it. It got to the point that I was No longer able to leave my house for fear I would get sick and embarrassed. M 59 3 years
30
6/24/2015
 1  insulin resistence Heart palpitations,pain in breast bone,weak,tired, no appetite,pin in left arm going down to left hand and fingers.pain on stomach Made me feel ill from the start but I thought will continue maybe its just my first time but I just got worse F 39 3 months
500mg
6/2/2015
 1  PCOS Headaches, muscle pains, suicidal thoughts, behavioral changes similar to being high or drunk, loss of love for loved ones, loss of feeling in hands, dizziness, lightheaded. This drug ruined my life. Please, do NOT take Metformin. F 15 2 months
1000MG 3X day
4/26/2015
 1  Type 2 diabetes , pcos I had chest pain, diahreha, vomiting and nausea. I also had severe head aches and the medicine didn't help. I've lost my appetite for everything and everything hurts me. This medication has ruined my life F 15 3 months
2000mg
3/1/2015
 1  Type 2 diabetes It turned me into a ticking poop bomb. I could have sudden and explosive diarea at any time, as well as constant upset stomach. I stopped taking it and became regular again, and I felt a lot better. And it did nothing for my blood glocose level. M 55 3 weeks
500 mg 2X day
6/29/2012
 1  PCOS horrible, constant diarrhea at any dosage. could not live a normal life on this drug. F 31 4 months
2000
12/28/2011
 1  PCOS Nausea, loose stools, headaches I took metformin for my PCOS and never lost any weight. I never had elevated blood sugar levels. I am now unable to eat any meat products due to the nausea, and am suffering from a severe vitamin b12 deficiency. Since I quit taking to metformin, I can at least eat what little I can without running to the bathroom. Not sure if this drug caused all my problems, but beware ob/gyns who think this is the answer to PCOS. Now I can't even touch my hair without if falling out or breaking. F 36 7 years
850 2X day
3/21/2011
 1  type 2 diabetes @500MG had some stomach pains and diarreah.@1000MG had severe fatigue and chest pain.I had pains in my stomach with diarreah.left side of chest had numb deep pain. Kept explaining this to my doctor he was no help for months.I just finally told him I refuse to take it any more.I was so sick I thought I had cancer or something.I kept working and was in so much pain I thought I would have to quit my job because of the physical pain I was in. M 39 4 months
500 mg 2X day
9/3/2010
 1  Weight loss to counteract gain Constant liquid diarrhea. Horrible stomach cramps. Sometimes if I eat a banana it helps, but not every time. Can't go anywhere unless it has bathroom. It has limited my life and my families lives incredibly. I would NEVER recommend this to anyone! F 36 1 months
500mg 2X day
8/14/2010
 1  Weight loss, insulin resistant Extreme bloating causing painful abdomen, constipation, gas. I decided to add my feedback because my experience has been so OPPOSITE of everyone else. My bloating was so severe that I couldn't button my pants. I actually looked like I gained weight on this. The gas was awful too. I stopped taking it on my own because after 3 weeks my symptoms did not subside. F 47 3 weeks
9/26/2009
 1  weightloss due to lypodystrophy constant, explosive diarrhea I have left more pairs of dirty underwear in bathrooms than walmart sells in a month. Chronic diarrhea, explosive and uncontrolable. Constantly looking for the nearest toliet. M 38 1 years
9/21/2009
 1  type II FECAL INCONTINENCE-and it took me months to figure out it was the Metformin. I also have had a lot of trouble breathing and I never made the connection to Metformin. I broke out in a really bad rash, and stopped taking it, the FI went away, so I asked Doc to give me something new. DON'T TAKE METFORMIN! F 38 6 months
9/4/2009
 1  First time script for Diabetes II Nausea, dizziness, smell sensitivity to wanting to vomit, flu-like symptoms Don't even remember the dosage, probably low. Within 10 days, as it increased daily, I felt like I had the flu plus a few other symptoms. I had to leave work early, go to bed and hope I felt better in the morning after the drug had left my system. Doctor didn't change dosage. F 52 10 days
8/10/2009
 1  Type 2 Diabetes Diarreah, joint pain, nausea, weakness, weight gain, peripheral edema, blood disorders, High triglycerides, kidney and liver problems. I took it for a year and 1/2 and now all my health is messed up. I've got organ damage because of Metformin, Januvia and Glucotrol. Please, check always about allergic reactions to medications before taking them so you don't end up like me. Now I am allergic to all Diabetes Oral medications. Good Luck! You may email me if you need further info. M 40 1.5 years
7/28/2009
  

GLUCOPHAGE  (METFORMIN HYDROCHLORIDE):  Metformin is used with a proper diet and exercise program and possibly with other medications to control high blood sugar. It is used in patients with type 2 diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke. Metformin works by helping to restore your body's proper response to the insulin you naturally produce. It also decreases the amount of sugar that your liver makes and that your stomach/intestines absorb.   FDA Approval Date: 1995-03-03 (Sources: U.S. Centers for Medicare Services, FDA)

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