GLUCOPHAGE Reviews (METFORMIN HYDROCHLORIDE)

Average Rating: 3.4 (586 Ratings)

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GLUCOPHAGE  (METFORMIN HYDROCHLORIDE):  Metformin is used with a proper diet and exercise program and possibly with other medications to control high blood sugar. It is used in patients with type 2 diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke. Metformin works by helping to restore your body's proper response to the insulin you naturally produce. It also decreases the amount of sugar that your liver makes and that your stomach/intestines absorb.   FDA Approval Date: 1995-03-03 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on GLUCOPHAGE: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR GLUCOPHAGECOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  PCOS The only side effect I've had is diarrhea, only on the first day of taking it. I see so many horror stories about this medicine. If you do not want to get violently ill, you have to eat right! This medicine does not tolerate carbs, so every meal has to be limited to a small amount of good carbs (i.e no white carbs). If you eat something bad, it's going to come out in the form of horrible diarrhea and nausea. Take the pill in the middle of your meal to avoid side effects as well. My period arrived in the first 2 days of taking it, I've lost 4 pounds, and my face is clear. I feel much better already! F 28 5 days
500 2x/day
11/21/2016
Email
 5  Type 2 Had taken plain Metformin in past with very bad stomach issues. Now am taking Metformin HCL ER (extended release) with almost no issues. F 66 1 years
500 2X day
11/9/2015
 5  Trying to conceive / pcos I got pregnant! I was diagnost with PCOS about 15 years ago. I was using BCP and didn't have a period for about 10 yrs. Went off BCP to try to have a baby, and nothing happened for about 2 yrs. Doc put me on Met to help with ovulation and such. I had sporatic periods, and then just didn't monitor them. I went in for an exray and was asked if I possibly could be pregnant. I said "anything is possible". Nurse came in and told me I was! Turned out I was 3 months along :) That was 4 yrs ago, and our baby boy is 3 yrs old and healthy. If you have PCOS and trying to get pregnant with no success, try this med! I stopped it after finding out I was pregnant, and after I gave birth, my periods have slowly dissapeared again (which is fine with me!) F 35 4 months
500 3X day
12/21/2013
 5  insulin resistance I lost 60 lbs on it not even trying. Definitely curbs sweets cravings. Horrible explosive diarrhea with cramping tho. But overall makes my periods 100% regular and on time.. and I conceived. F 24 3 years
1500-2000
12/2/2013
 5   I am 28 years old and and was recently diagnosed with PCOS, although I think I've had it for years and years. I started menstrating at 11! I had such severe cramps that I'd stay home from school and in my mid 20's pretty much stopped having a period and started the most devastating acne:( I am not pre-diabetic or really overweight (I always have 10 pounds to lose) but I am taking it to regulate my cycle, possibly clear up my hormonal and cystic acne:( and start to ovulate so one day I can have babies! My fiance is a family physician and was weary about me trying this med because of the side effects but we did some research and found almost definite ways to prevent the gastric and bathroom problems: -Always eat before and a little after taking the med. -Stay away from dairy, carbs (sugar and flour) -Limit your fruits to only a few a day If you stick to this plan you really shouldnt have any drastic side effects:) I have noticed an IMMEDIATE change in appetite and seems it is MUCH easier to eat a healthy diet because the carb cravings are pretty much non-existent!!! Feels like a miracle! I was always always a sugar and carb feen! Felt like it was controlling my life and it was so so difficult to resist junk. I've only been on it 4 days but really feel like its a life changer! Hopefully it sticks around! I will update again giving it more time:) F 28 4 days
500mg 1X day
3/5/2013
Email
 5  Pcos/insulin resistance First week it was rough. I adjusted my eating to be more low carb and lost 40 pounds in 3 months. My blood sugar is perfect now. Love it. F 38 2 days
500mg
1/2/2013
 5  Insulin Resistance/Pre-Menopause I have not experience any major side affects except some brief nausea which passes as quickly as it comes. I am thrilled and I am only 3 days into it. I have already lost 2.3 lbs(and this is my PMS week where I usually gain 4-5 lbs) and have energy like I haven't had in a while. My appetite has decreased and my cravings for real sugary foods have pretty much disappeared. I will repost weekly to update this information. F 40 3 days
500MG 1X day
3/12/2012
 5  Pcos & weight loss & insulin resist Mild nausea, horrible migraines NSAIDs didn't help, complete loss of appetite, no sugar or carb cravings. I love this medication! My migrains have subsided and the nausea is bearable but the real kicker is the fact that i have absolutely no appetite whatsoever... Everytime i even think about food i feel sick. Thats extremely strange for me considering i used to love food. i guess you could say that i had a sweets/carb and grease addiction. i also used to drink nothing but diet coke and now i can't stand the thought of it... and i quit smoking too! this medication has been a life saver :-) F 25 1 months
2000mg
12/15/2011
 5  PCOS and weight loss Horrible diarrhea and vomiting the first few weeks until I realized that I needed to space 6 hours between doses. Now I just have loose stools and the occasional diarrhea. I love this medicine. After 4 years of constant weight gain no matter what I did (100 ibs in 4 years) and a doctor that wouldn't help me, I switched doctors and within 4 days of my first visit she put me on Glucophage. I have already noticed a big difference. I'm no longer hungery all the time. I have much more energy. My acne has cleared up somewhat and my facial hair is starting to disappear. I find out next week just how much weight I've lost, but I can already tell that I've lost some. F 22 4 weeks
500mg 3X day
11/2/2011
Email
 5  Insulin Resistant/Possible PCOS Lack of appetite/no sugar or carb cravings (HUGE achievement)/frequent urination In the past 3 years, I've gained 50-60lbs for no apparent reason. My mom has lived with this weight around her waist for years with no explanation. Finally, my OB-GYN diagnosed me with Insulin Resistance 3 days ago, and it seems like I have ALL the symptoms! I never would have guessed that my acne and severe fatigue could be associated with this. Anyway, I am taking 500mg once daily, and I will continue to add 500mg weekly until 1500mg daily. So far, I have not had a BM (which is normal for me because of my severe constipation). No stomach upset so far. I have increased urination from 3 times daily to 6 times daily, and this is hopefully solving my water retention! I have no desire for sugary or fatty foods, and my carb cravings are finally something that I can manage!!! So far I'm quite optimistic, but I will update in a few days. Lets hope for some weight loss/regularity/and a menses this month!!! F 25 3 days
500mg 3X day
9/10/2011
Email
 5  PCOS Diarrhea & stomach cramps over the 4 weeks buiding up to the full dose (+500mg per week util I reached 2000mg)...but symptoms were eased with a low carb diet It has worked wonders for me, after a few weeks my periods were every 33-35 days (rather than every 3-9 months)...I have lost weight (12 kg to date) but through a low carb diet & gentle exercise rather than the Metformin alone (I think if I upped the cardio & cut back further on the food the results would be more drastic)...I am more energetic and am sure the facial hair is less noticeable....It has transformed my life (and will hopefully enable us to create one in the near future) xxx F 37 7 months
1000mg 2X day
6/9/2011
 5  type 2 diabetes A bit of nausia and loss of appetite until I lost about 30 pounds. I'm sure the weight loss helped me a lot. I am off medication now, but I stuggle to keep my blood sugar normal. Type 2 diabetes is reversable. M 57 9 years
500Mg 3X day
3/5/2011
Email
 5  Insulin resistance Nausea the first few days, "buzzed" feeling but focused and energized, appetite decrease, less obsession with food, totally turned off by carbs Didn't experience too much of the gastro side effects (I think) because I have been eating minimally processed / paleo / whole foods for several years before starting Metformin. I'm sleeping better and stopped snoring 3 days after starting. I know I've lost a few pounds but haven't stepped on a scale in a while so don't have exact numbers. I do get pretty hungry when it's time to eat but it is a physical hunger. I'm not suffering fogginess or confusion from highs and lows of blood sugar. I am very hopeful. Nothing else has helped me lose this abdominal fat. Will keep you posted. M 47 1 weeks
500mg 3X day
2/25/2011
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 5  PCOS F 23
1500 XR 1X day
2/19/2011
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Patient History
 5  PCOS stomache cramps and diarrhea after that, loose stools, tiredness so I take it at night As soon as I started taking it, my period that had gone on for 60 days just stopped. My energy level has improved significantly in the past 2 weeks, and my mood has been elevated a lot. I feel like this drug is going to change my life for the better. No weight loss, but I have the energy to get to the gym and really feel I can do things of my own volition now! F 22 14 days
500mg 1X day
12/14/2010
Email
 5  PCOS and insulin resistance I have occasional headaches and stomaches. Most days I have explosive diarrhea but other days it is regular. The smell is awful. I have very painful cramps before the explosive kind. I have to stop what I am doing because of the pain. I have lost more than 50 pounds while on this medication. I have less body hair and I have a lot more energy. I had a loss of appetite. It also regulated my periods. The pain was worth it, I feel great! F 21 2.5 years
750 2X day
12/1/2010
 5  PCOS/Insulin Resistant First night mild cramping, soft stools and nausea I have already notice an increase in my energy level. Thanks metformin, i'm so excited about our future relationship together.. lol.. im hoping to get pregnant in the near future, no rush but i am so happy because there is "HOPE" thats what i have been praying for. F 28
500mg 2X day
11/18/2010
 5  insulin resistance/to help wt loss none lasting. started slowly at MD suggestion, 500 mg then up to 1000 in one week My NP offered this to me to aid weight loss. I had excellent results - 296 to 215 in about 10 months and have kept it off. I was aware going in that I would only lose about 60% of what I needed to lose to be of normal weight, but was willing to give anything a try. I watched my portion size and carbs, but essentially the weight fell off. F 55 2 years
1000mg 1X day
9/4/2010
 5  PCO, Miscarriage,Insulin Res,Weight Explosive diarrhea intermittently for two weeks, stomach pain, then tolerance. Must follow a zone type diet (a bit of protein and low glycemic at every meal) or get light headed. I was on Glucophage before it was FDA approved for preventing miscarriage under the guidance of an OB Gyn in the research fertility field. This is a miracle drug for me. After years of miscarriages (at least 7) I was able to carry two beautiful children to term and now they are in gradeschool. All of the side effects are worth it for the use of preventing miscarriage. I have had PCOS for many years. I did not have any weight problems until after I got assaulted by a stranger and I had lingering Post Traumatic Stress Syndrome and the hormonal effects of it (high adrenaline, cortisone problems) and in addition my physical injuries from the assault were major so I had great pain and difficulty exercising. I gained a tremendous amount of weight after the assault. However I have read that some researchers think that PCOS and stress, especially great stress like this assault where someone tried to kill me and was not caught and may have been able to come back and find me (prolonging the adrenaline PTSD response and fear)... can trigger more severe symptoms as far as PCOS and Insulin Resistance. If there are any researchers in this area who are pursuing this theory you may contact me about stress and PCO, etc. I discontinued Glucophage after the first trimester in both pregnancies I believe, it has been a while so I have forgotten. I now have re-started taking the medicine in order to handle the PCO symptoms of weight gain, period irreg, hirsutism, acne, insulin resistan F 46 365 days
500 2X day
7/19/2010
Email
 5  Weight Loss VERY BAD cramping the first day. Never felt anything like it... But didn't accredit that to taking Glucophage. I am hoping for the best. I weigh over 350 pounds. So any weight loss help will be wonderful! We will see... F 25 2 days
500mg 2X day
6/3/2010
Email
  

GLUCOPHAGE  (METFORMIN HYDROCHLORIDE):  Metformin is used with a proper diet and exercise program and possibly with other medications to control high blood sugar. It is used in patients with type 2 diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke. Metformin works by helping to restore your body's proper response to the insulin you naturally produce. It also decreases the amount of sugar that your liver makes and that your stomach/intestines absorb.   FDA Approval Date: 1995-03-03 (Sources: U.S. Centers for Medicare Services, FDA)

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