TAXOL Reviews (PACLITAXEL)

Average Rating: 3.5 (99 Ratings)

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TAXOL  (PACLITAXEL):  Paclitaxel is used to treat various types of cancer. It is a cancer chemotherapy drug that works by slowing or stopping cancer cell growth.   FDA Approval Date: 1992-12-29 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR TAXOLCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Triple negative breast cancer Severe joint pain/stiffness in fingers knees and hips and shoulders.mild tingling to bott of feet. Crazy hot flashes. Occasional headaches. I received 12 weekly rounds of taxol.i had to stop carboplatin after 4 doses due to severe neutropenia F 39 3 months
6/16/2016
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 5  IDCS Breast Cancer Continued form previous post:week 5: mouth sores for a couple of days. Very achy from the granix-. I never dip below 4 again so did not take additional shots for the rest of the chemo. Hair continues to fall out, but still cant notice. Week 6: severe itching/tingling of feet, mostly at night. Drives me crazy. Double my L-Glutamine to 1500 mg/2x day and it goes away. I stay on that for the next 11 weeks. Hair coming out more. Week 7: Noticeable difference in energy level. Days 3-5 tired. Hair continues to fall out. Nausea in middle of night which wakes me up, but lasts only a few minutes. Week 8: tired, hair falling out. Week 9-12: Tired. Hair really falling out. Weird cold sensation in my veins when I get the chemo, but not sure if from taxol or the premeds. I almost passed out week 11 so they stopped it for 30 min and waited until I felt better. Week 13.Felt the worst I did the entire time. Tired, low energy, with some nausea in the night that woke me up, but again short la #2 of @ post with week by week descriptions for Taxol F 49 12 weeks
80 mg/KG 1X W
12/31/2014
 5  IDCS Breast Cancer, post lumpectomy I really wanted the week by week, so here is what it was like for me. This is a blow by blow but overall let me say that on a scale of 1-10 (10 being awful), even on the worst days I would give it a 4. I never missed a day of work, though I did go to bed earlier and sometimes slept in. At week 14 I did a fast, 1 week turn around trip to Africa, and though tired, actually felt mostly OK. Week 1: No side effects Week 2: mouth sores for about 3 days, the first day it felt like a burned my mouth (like after you eat a hot piece of pizza) The third was somewhat sore, like having a bunch of cold sores. Then it just went away on its own Only came back for a couple of other days around week 5. Also low white blood cell count (3) from a starting point of 14. They give me neupogen the day before next session (Week 3). It works (WBC 27) but really makes me feel achy in my bones for a day. Insurance will not cover, so they switch me to granix. Went for a 3 day 35mile backpacking trip aft Diagnosed at 48. Triple positive so had weekly taxol for 12 weeks starting 5 weeks post surgery to remove lump. Also taking Herceptin which I started first. Side effects worse than Herceptin alsone, but overall quite manageable. I worked the entire time, continued to exercise (but was more tired). F 49 12 weeks
80 mg/KG 1X W
12/31/2014
 5  LB Mastectomy (After AC chemo x 4) As the cycles progressed - extreme fatigue (could never have imagined it happen to me, It overwhelmed me) Metallic taste in mouth (drove me insane) Finger and Toe nails affected (mainly index fingers and large toe nails) Brain Chemo My hair fell out almost immediately with the AC chemo, but with Taxol, the last of it fell out and then my eyelashes and eyebrows all fell out and my body hair followed suit. If it works, go for it! as much as I did not like the side effects of it, you manage to get through it. The recovery from the side effects after the 12 cycles has been fairly rapid for me. So I am delighted. F 60 12 weeks
80mg 1X day
8/31/2014
 5  Stage 4 Breast cancer Total hair loss for entire body, peripheral neuropathy, joint pain, neutropenia , tolerable fatigue, rapid heart rate Saved my life and thankful for this drug. Breast tumor and 2 small areas in liver were completely gone after first month (3weeks on & 1 week off ) of treatment with concurrent palliative radiation of lower back. Now 7 months later and addition of Avastin at month 5 , I am NED (no evidence of disease) and even bone detioration is gone. I started with mass in left breast, 2 small areas in liver, 3 metastases to the spine and severe pelvis, ribs and sternum bone lytic lesions. F 45 7 months
90mg
5/26/2014
 5  Breast cancer stage 1 removed Loss of hair, still have eyebrows/lashes. A little fatigue comes unexpectedly but then back to normal. Half way through hope all goes well. Taxol is an insurance policy for me not to get cancer again...so I am happy if it works! F 50 6 weeks
1X W
1/6/2014
 5  Breast Cancer Fatigue. Taxol helped save my life. I was Stage 2B when I started treatment with a tumor 4 1/2 cm in size. Opted for neo-adjuvant chemo in the hopes of saving my breast. Started with dose dense A/C for four treatments every other Tuesday and ended with dose dense Taxol, four treatments every other Tuesday for a total of 16 weeks of chemotherapy. Because of the positive response to chemo my tumor was shrunk to 1.1cm and removed successfully. Followed with daily radiation for 7 weeks. Six years post treatment I am completely disease free. F 58 8 weeks
2X M
3/6/2013
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 5  stage I grade 3 triple negative BC intermittent very mild neuropathy, some stumbling, but not too bad. a little fatigue, but not too bad. After the Epirubicin and Cytoxan, the Taxol is wonderful I think the pre-meds are the primary cause of my tiredness and malaise for a day or two after the treatment. my WBC and RBC counts are low, but staying constant I am ravenous due to the dexamethasone pre-med, but try to eat lots of proteins to keep my blood counts up. I take a couple tablespoons of blackstrap molasses every day, and I'm convinced that that is helping with the blood counts. F 49 6 weeks
12 weeks 1X W
5/15/2011
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 5  MD Anderson I am in my 9th week of Taxol treatments and have not experienced any major side effects. (oh, except for my hair thinning out) i take my treatments on Saturday mornings so I have the weekend to rest. I still work full time in upper management. Everyone responds differently to treatment. F 40 9 weeks
1X W
2/22/2011
 5  BC Stage3A Hair loss, nausea, neutropenia and anaemia. I continued working (office), but had to quit the gym, which I resumed 3 months after the last chemo and surgery. I had a giant tumor, which after Taxol reduced to 10.5 cm but had free margins. I'm currently finishing my rads and taking Armidex. Apart from the anaemia and neutropenia, which required some extra care the treatment went smoothly. 3 months after I still have a bit of neutropenia but my quality of life is OK, besides the doctor says I'm cancer free! F 48 6 months
1X O
2/5/2010
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 5  Stage IIA Breast Cancer After 4 treatments of AC, Taxol although isn't a walk in the park is easier. Side effects include bone aches days 3 - 5 usually starting in the afternoon. Fatigue. Bowel problems. Mucous in stool and stomach pain. No nausea. Nose bleeds. New side effect - rash on hands. Lost my hair during AC and seem to be losing more with the Taxol. Currently on 8th cycle of a 12 week low dose Taxol. Looking forward to having some energy again. F 51 12 weeks
10/26/2009
 5  Stage I Breast Cancer Some fatigue, short-term memory loss (but not enough to affect my work), very upset stomach for three days following treatment, diarrhea/constipation and loss of menstrual cycle. NO mouth sores, joint pain, nail problems, neuropathy, or total hair loss (just some thinning of my hair, but not my facial or bodily hair). I was prepared for the worst, but found Taxol to not be as bad as I thought it would be. I just finished my last dose on August 13th. I participated in a clinical trial where I received Taxol weekly for 12 weeks. I think the data is showing that a lower dose administered weekly is easier on patients. At least is was for me. I was able to work every day but the day I got the Taxol. The worst symptom for me was my stomach/bowels. I didn't lose my hair. It continues to fall out, now 3 weeks post Taxol, but I never lost enough that I had to wear a wig. I did, however, have to have high does of Decadron because I had a severe reaction to my first infusion. After that (which wasn't fun), it was faily unremarkable. I have three children under the age of 4 and was able to care for them without them ever knowing I was sick. So, I recommend Taxol, and definitely given weekly over 12 weeks. Hope this helps :-) F 37 12 weeks
9/6/2009
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 5  Breast Cancer Stage IIIB Neuropathy in hands and feet; rash on my face, progressive memory problems/light headedness; weight loss/loss of appetite; loss of hair on entire body I am sure this is what helped me to have complete response; more and more research is showing weekly dose is the way to go; I did it because of side affects I had with AC; I still have back pain and numbness 3 months later but I show no cancer on my scans and path report F 53 12 weeks
8/29/2009
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 5  metastic breast cancer F 50 3 weeks
8/8/2009
 5  Stg.4 OvarianCancerPrognosis 2 mos. Tired, weak.#10 pain @times in feet and legs.It has been 16yrs. this June and is difficult to remember everything about the treatments. But I have SUFFERED incredible pain since then. Every hair on my body was lost during treatment but came back.That was nothing compared to this last 16 yrs. I would take it again because it helped save my life. I have memory loss and difficulty concentrating. Just something else to work on. LOL. Thanks to my Dr for putting me on anti-depressants. That in itself helped so much. Knowing that I am mind, spirit and body I went to work on all three. I "raged against the dying of the light", that ol' cancer. I suffer daily but would have missed so very much. Peripheral neuropathy and shortly after I completed the Taxol and Cysplatin I was diagnosed with Fibromyalgia.Some folks think I'm lying about having Ovarian C.especially metastasis but I have the papers to prove it. First I had to decide whether I REALLY wanted to live. Then I started kicking butt My story is too long to tell now but I'm still amazed that the bark of the Yew tree helped save my life. After 3 rounds we did another CT scan and the mass of 3 tumors in my pelvic area the size of grapefruit were gone. Still had many small tumors "lining the wall of my abdominal region." They had to put me in intensive care to administer it every 21 days because it was so strong. I was diagnosed June 1, 1993. I'm still here.The staph in my port. almost took me out! Sometimes when it gets so bad you just gotta laugh..it helps. F 65 9 months
6/22/2009
 5  breast cancer fatigue I am on weekly taxol for twelve weeks, just finished my fourth. So far my only side effects are some fatigue after the decadron steroid wears off, and a little stomach acid so I avoid spicy foods. No hair loss yet, although I'm expecting it. No neuropathy or joint pain as others have described. No other side effects. I was on AC for four cycles before and it was horrible. Compared to that, this is a walk in the park! F 48 12 weeks
6/19/2009
 5  Stage 1 Uterine cancer Hair Loss / temporary very mild neuropathy I began Taxol on a weekly basis (3 weeks on 1 week off) in Nov. 2008. Due to thinning I finally cut off my hair the middle of Jan. 2009 and went to a wig. I have not had any of the normal side effects - no nausea, fatigue, body aches. I work 32+ hrs. a week (75% on my feet)and have not missed a day of work. I take myself to and from treatments. My treatment effectiveness is being monitored by CT scans and CA125 blood tests for tumor markers. Both show my tumors are rapidly shrinking. I was determined not to let Taxol get the better of me. F 61 9 weeks
1/19/2009
 5  Stage IIIb ovarian cancer I began taxol and carboplatin following my surgeries, partial hysterectomy when cancer was found, then removal of my ovaries (both cancerous), debulking of largest tumors in the abdominal/chest cavity, and staging 3 weeks following my initial surgery.I took 6 treatments of taxol and carboplatin, I think every 5-6 weeks, and was in remission on PET scan upon completion of treatments.I did have problems with decreased white cells and had injections daily for 5-7 days following chemo to boost my white cells (which added more extreme bone pain).I took scheduled doses of Phenergan for 3-4 days following treatments to control nausea.I had flushed face, shoulders, and chest on the second day of treatment (which I was told was a side effect of the steroids given with treatment to prevent side effects of the chemo).On day 2 following the chemo I had severe bone and muscle pains and learned to take scheduled doses of Lortab the day of treatment for 3-4 days to keep pain under control.About 4 day Started just taxol 2 months later.The day of my 3rd treatment they discovered my heart rate was 144, treatments were stopped.I went through an extensive cardiac workup.Question if chemo caused the problem,I had never had trouble before.Treatments were resumed.I have now had 9 treatments/3 more to go.CA125 levels are 5-6.Have had no problems with low white cells just on taxol.Treatments 8&9 I have noticed worse side effects for longer period of time with bone, muscle, nerve pain.Also have extreme pain both knees,trouble walking after sitting for a prolonged period of time.Walking does seem to ease these problems but I still move slowly.I was a very on-the-go,energetic person before all this.My energy level is now zero.I find it difficult to accomplish half of what I used to.I work 37 hrs. a week, barely get through it & and take care of my pets.Have had a 50+ lb wt gain from the steroids with treatments,fluid retention.Have bouts of depression, back pain (have DJD but back pain F 54 15 months
11/10/2008
 5  Metastatic Bladder Cancer Following my diagnosis of metastatic bladder cancer to the bone of my neck and spine I was put on unlimited morphine & cycplatin & Gemzar. Lasted only one cycle on regime, Scans showed the cancer was progressing with treatment. Went on a 9 day bucket list cruise. Was put on Taxol & Gemzar. After the first treatment spent day 2 post treatment in bed with chills, fever & fatique. By day 5 fatique subsided. I am now 2-1/2 months into treatment. Side effects are predictable. Day 2,3,4 post treatment some fatique, loss of hair, including nasal lining, I always had osteoarthritis so I can not attribute joint & muscle pain to taxol. Taxol was prescibed as pallative, but I now am almost normal, scan show the cancer has stopped progressing and bone mass in regenerating. The results of Taxol have been nothing short of miraculous. Prior to treatment I required vicodin every three hours, I have reduced my pain medication to every 6 hours and often forget to take the drugs. Prior to Taxol I could not stand or sit erect for more than 15-20 minutes due to pain in neck and spine. I am now remodeling my home, washing cars and driving again. My diagnosis in Oct was terminal, but I now think I may again have a future. M 66 2.5 months
6/4/2008
 5  stage 3 breast cancer I have been off taxol for 1 year.The right leg is inflammed and has spasms,with pain.Right down to the big toe.I used to enjoy dancing and I do,nt feel light on my feet.I won,t give up yet! Yes,I sat most of the year and I,m better than 6 months ago when I had to hold on to a shopping cart in the store and if i let go ,I couldn.t make it to the car.I take the super greens ,I eat lots of green salads,drink detox teas.Your bodies must become more alkaline than acidic.Acid foods cause joint pain right down to cancer.Meat,dairy,sugar,white flour,coffee ect.are to be eaten sparingly, if not at all! Try salads of spinich,other hearty greens ,avacado cucumber,lime juice.Don.t forget berries,cherries,strawberries.olive oil,nuts fish,omega oils,vitimins too. F 54 2 months
3/10/2008
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TAXOL  (PACLITAXEL):  Paclitaxel is used to treat various types of cancer. It is a cancer chemotherapy drug that works by slowing or stopping cancer cell growth.   FDA Approval Date: 1992-12-29 (Sources: U.S. Centers for Medicare Services, FDA)

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