TAXOL Reviews (PACLITAXEL)

Average Rating: 3.5 (99 Ratings)

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 DNA DAMAGING DRUGS

 Type: Rx Drug

  

TAXOL  (PACLITAXEL):  Paclitaxel is used to treat various types of cancer. It is a cancer chemotherapy drug that works by slowing or stopping cancer cell growth.   FDA Approval Date: 1992-12-29 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Gender with females listed first (reviews with no gender reported listed before females).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR TAXOLCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Return of tumour Nauseous, constipation, breathless, fatigue, extreme tingling in feet and hands. Could not have hot shower as it seemed too hot for my skin. Hair loss, lost some control over bladder but this has returned. A dreadful chemo . Skin rash covering entire torso, under arms etc the rash changed the colour of my skin. 73 14 weeks
10/12/2019
 1  2b met. Breast Cancer Terrible neuropathy in feet had nerve test permanent nerve damage. Should have used different drug or been administered drug differently. I blame doctor for that. But after nine years cancer free but also thank the Lord for that It has destroyed my life 56 3 months
??
11/20/2019
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 5  Breast Cancer Stage IIIB Neuropathy in hands and feet; rash on my face, progressive memory problems/light headedness; weight loss/loss of appetite; loss of hair on entire body I am sure this is what helped me to have complete response; more and more research is showing weekly dose is the way to go; I did it because of side affects I had with AC; I still have back pain and numbness 3 months later but I show no cancer on my scans and path report F 53 12 weeks
8/29/2009
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 5  Stage I Breast Cancer Some fatigue, short-term memory loss (but not enough to affect my work), very upset stomach for three days following treatment, diarrhea/constipation and loss of menstrual cycle. NO mouth sores, joint pain, nail problems, neuropathy, or total hair loss (just some thinning of my hair, but not my facial or bodily hair). I was prepared for the worst, but found Taxol to not be as bad as I thought it would be. I just finished my last dose on August 13th. I participated in a clinical trial where I received Taxol weekly for 12 weeks. I think the data is showing that a lower dose administered weekly is easier on patients. At least is was for me. I was able to work every day but the day I got the Taxol. The worst symptom for me was my stomach/bowels. I didn't lose my hair. It continues to fall out, now 3 weeks post Taxol, but I never lost enough that I had to wear a wig. I did, however, have to have high does of Decadron because I had a severe reaction to my first infusion. After that (which wasn't fun), it was faily unremarkable. I have three children under the age of 4 and was able to care for them without them ever knowing I was sick. So, I recommend Taxol, and definitely given weekly over 12 weeks. Hope this helps :-) F 37 12 weeks
9/6/2009
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 5  Stage IIA Breast Cancer After 4 treatments of AC, Taxol although isn't a walk in the park is easier. Side effects include bone aches days 3 - 5 usually starting in the afternoon. Fatigue. Bowel problems. Mucous in stool and stomach pain. No nausea. Nose bleeds. New side effect - rash on hands. Lost my hair during AC and seem to be losing more with the Taxol. Currently on 8th cycle of a 12 week low dose Taxol. Looking forward to having some energy again. F 51 12 weeks
10/26/2009
 5  Stg.4 OvarianCancerPrognosis 2 mos. Tired, weak.#10 pain @times in feet and legs.It has been 16yrs. this June and is difficult to remember everything about the treatments. But I have SUFFERED incredible pain since then. Every hair on my body was lost during treatment but came back.That was nothing compared to this last 16 yrs. I would take it again because it helped save my life. I have memory loss and difficulty concentrating. Just something else to work on. LOL. Thanks to my Dr for putting me on anti-depressants. That in itself helped so much. Knowing that I am mind, spirit and body I went to work on all three. I "raged against the dying of the light", that ol' cancer. I suffer daily but would have missed so very much. Peripheral neuropathy and shortly after I completed the Taxol and Cysplatin I was diagnosed with Fibromyalgia.Some folks think I'm lying about having Ovarian C.especially metastasis but I have the papers to prove it. First I had to decide whether I REALLY wanted to live. Then I started kicking butt My story is too long to tell now but I'm still amazed that the bark of the Yew tree helped save my life. After 3 rounds we did another CT scan and the mass of 3 tumors in my pelvic area the size of grapefruit were gone. Still had many small tumors "lining the wall of my abdominal region." They had to put me in intensive care to administer it every 21 days because it was so strong. I was diagnosed June 1, 1993. I'm still here.The staph in my port. almost took me out! Sometimes when it gets so bad you just gotta laugh..it helps. F 65 9 months
6/22/2009
 5  metastic breast cancer F 50 3 weeks
8/8/2009
 5  Breast cancer stage 1 removed Loss of hair, still have eyebrows/lashes. A little fatigue comes unexpectedly but then back to normal. Half way through hope all goes well. Taxol is an insurance policy for me not to get cancer again...so I am happy if it works! F 50 6 weeks
1X W
1/6/2014
 5  Stage 4 Breast cancer Total hair loss for entire body, peripheral neuropathy, joint pain, neutropenia , tolerable fatigue, rapid heart rate Saved my life and thankful for this drug. Breast tumor and 2 small areas in liver were completely gone after first month (3weeks on & 1 week off ) of treatment with concurrent palliative radiation of lower back. Now 7 months later and addition of Avastin at month 5 , I am NED (no evidence of disease) and even bone detioration is gone. I started with mass in left breast, 2 small areas in liver, 3 metastases to the spine and severe pelvis, ribs and sternum bone lytic lesions. F 45 7 months
90mg
5/26/2014
 5  LB Mastectomy (After AC chemo x 4) As the cycles progressed - extreme fatigue (could never have imagined it happen to me, It overwhelmed me) Metallic taste in mouth (drove me insane) Finger and Toe nails affected (mainly index fingers and large toe nails) Brain Chemo My hair fell out almost immediately with the AC chemo, but with Taxol, the last of it fell out and then my eyelashes and eyebrows all fell out and my body hair followed suit. If it works, go for it! as much as I did not like the side effects of it, you manage to get through it. The recovery from the side effects after the 12 cycles has been fairly rapid for me. So I am delighted. F 60 12 weeks
80mg 1X day
8/31/2014
 5  IDCS Breast Cancer Continued form previous post:week 5: mouth sores for a couple of days. Very achy from the granix-. I never dip below 4 again so did not take additional shots for the rest of the chemo. Hair continues to fall out, but still cant notice. Week 6: severe itching/tingling of feet, mostly at night. Drives me crazy. Double my L-Glutamine to 1500 mg/2x day and it goes away. I stay on that for the next 11 weeks. Hair coming out more. Week 7: Noticeable difference in energy level. Days 3-5 tired. Hair continues to fall out. Nausea in middle of night which wakes me up, but lasts only a few minutes. Week 8: tired, hair falling out. Week 9-12: Tired. Hair really falling out. Weird cold sensation in my veins when I get the chemo, but not sure if from taxol or the premeds. I almost passed out week 11 so they stopped it for 30 min and waited until I felt better. Week 13.Felt the worst I did the entire time. Tired, low energy, with some nausea in the night that woke me up, but again short la #2 of @ post with week by week descriptions for Taxol F 49 12 weeks
80 mg/KG 1X W
12/31/2014
 5  IDCS Breast Cancer, post lumpectomy I really wanted the week by week, so here is what it was like for me. This is a blow by blow but overall let me say that on a scale of 1-10 (10 being awful), even on the worst days I would give it a 4. I never missed a day of work, though I did go to bed earlier and sometimes slept in. At week 14 I did a fast, 1 week turn around trip to Africa, and though tired, actually felt mostly OK. Week 1: No side effects Week 2: mouth sores for about 3 days, the first day it felt like a burned my mouth (like after you eat a hot piece of pizza) The third was somewhat sore, like having a bunch of cold sores. Then it just went away on its own Only came back for a couple of other days around week 5. Also low white blood cell count (3) from a starting point of 14. They give me neupogen the day before next session (Week 3). It works (WBC 27) but really makes me feel achy in my bones for a day. Insurance will not cover, so they switch me to granix. Went for a 3 day 35mile backpacking trip aft Diagnosed at 48. Triple positive so had weekly taxol for 12 weeks starting 5 weeks post surgery to remove lump. Also taking Herceptin which I started first. Side effects worse than Herceptin alsone, but overall quite manageable. I worked the entire time, continued to exercise (but was more tired). F 49 12 weeks
80 mg/KG 1X W
12/31/2014
 5  Triple negative breast cancer Severe joint pain/stiffness in fingers knees and hips and shoulders.mild tingling to bott of feet. Crazy hot flashes. Occasional headaches. I received 12 weekly rounds of taxol.i had to stop carboplatin after 4 doses due to severe neutropenia F 39 3 months
6/16/2016
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 5  BC Stage3A Hair loss, nausea, neutropenia and anaemia. I continued working (office), but had to quit the gym, which I resumed 3 months after the last chemo and surgery. I had a giant tumor, which after Taxol reduced to 10.5 cm but had free margins. I'm currently finishing my rads and taking Armidex. Apart from the anaemia and neutropenia, which required some extra care the treatment went smoothly. 3 months after I still have a bit of neutropenia but my quality of life is OK, besides the doctor says I'm cancer free! F 48 6 months
1X O
2/5/2010
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 5  MD Anderson I am in my 9th week of Taxol treatments and have not experienced any major side effects. (oh, except for my hair thinning out) i take my treatments on Saturday mornings so I have the weekend to rest. I still work full time in upper management. Everyone responds differently to treatment. F 40 9 weeks
1X W
2/22/2011
 5  stage I grade 3 triple negative BC intermittent very mild neuropathy, some stumbling, but not too bad. a little fatigue, but not too bad. After the Epirubicin and Cytoxan, the Taxol is wonderful I think the pre-meds are the primary cause of my tiredness and malaise for a day or two after the treatment. my WBC and RBC counts are low, but staying constant I am ravenous due to the dexamethasone pre-med, but try to eat lots of proteins to keep my blood counts up. I take a couple tablespoons of blackstrap molasses every day, and I'm convinced that that is helping with the blood counts. F 49 6 weeks
12 weeks 1X W
5/15/2011
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 5  Breast Cancer Fatigue. Taxol helped save my life. I was Stage 2B when I started treatment with a tumor 4 1/2 cm in size. Opted for neo-adjuvant chemo in the hopes of saving my breast. Started with dose dense A/C for four treatments every other Tuesday and ended with dose dense Taxol, four treatments every other Tuesday for a total of 16 weeks of chemotherapy. Because of the positive response to chemo my tumor was shrunk to 1.1cm and removed successfully. Followed with daily radiation for 7 weeks. Six years post treatment I am completely disease free. F 58 8 weeks
2X M
3/6/2013
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 5  breast cancer I experienced severe myalgias & neuralgias while on the drug, plus neuropathy in hands and feet. The neuropathy in my feet is still there to a lesser degree after 5 years. I have experienced a loss of cartilage at my great toe and foot joints - something the orthopedic MD says he does not frequently see in "someone like me." It is extremely painful and there is really not much you can do about it, except surgery to fuse the toe. I am concerned that the cartilage damage has been caused by the Taxol and that other joints will be affected. Has anyone else experienced this???? F 8 weeks
11/30/2005
 5  Metastatic breast cancer Fatigue was the only important one; one day mostly in bed for each weekly cycle. My hair fell out, but who cares? None of the nausea/vomiting I've experienced with other chemo drugs. No peripheral neuropathy. Only very mild and occasional joint pain. I had 16 weekly doses of Taxol over about 6 months; 3 weeks on 1 week off with a long break over Christmas due to going on holiday rather than medical considerations. Having weekly doses seems to reduce the side-effects without reducing the efficacy (there is scientific evidence for this, not just my opinion). It was palliative in intent, and it has worked ie my various tumours have shrunk in size. F 44 6 months
3/12/2007
 5  breast cancer Side effects of Taxol were more severe than those experienced from Adriamycin/Cytoxin. With Taxol, slight numbness in fingertips and slight detachment of fingernails. Fatigue. Took glutamine and high-dose vitamin B6 to minimize side effects. Had GREAT result with first four A/C treatments. Tumor was further diminished by four treatments of Taxol to the point that my last treatment was optional. Took it anyway. I started chemotherapy very shortly after diagnosis in order to save my breast. My doc said neo-adjuvant therapy works in approx. 70% of patients. Glad I yook my chances! Chemo is no walk in the park, but it does help save lives (and breasts!) F 52 8 weeks
11/15/2006
  

TAXOL  (PACLITAXEL):  Paclitaxel is used to treat various types of cancer. It is a cancer chemotherapy drug that works by slowing or stopping cancer cell growth.   FDA Approval Date: 1992-12-29 (Sources: U.S. Centers for Medicare Services, FDA)

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