TAXOL Reviews (PACLITAXEL)

Average Rating: 3.5 (99 Ratings)

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TAXOL  (PACLITAXEL):  Paclitaxel is used to treat various types of cancer. It is a cancer chemotherapy drug that works by slowing or stopping cancer cell growth.   FDA Approval Date: 1992-12-29 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR TAXOLCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  metastatic laryngeal cancer to lung 1x weekly for 3 weeks then 1 week off ,just finished week 3, hair is thinning out mild bone pain and moderate fatigue. 15 more treatments ,hope it doesn't get much worse!! M 57 3 days
1/29/2008
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 5  Metastatic Bladder Cancer Following my diagnosis of metastatic bladder cancer to the bone of my neck and spine I was put on unlimited morphine & cycplatin & Gemzar. Lasted only one cycle on regime, Scans showed the cancer was progressing with treatment. Went on a 9 day bucket list cruise. Was put on Taxol & Gemzar. After the first treatment spent day 2 post treatment in bed with chills, fever & fatique. By day 5 fatique subsided. I am now 2-1/2 months into treatment. Side effects are predictable. Day 2,3,4 post treatment some fatique, loss of hair, including nasal lining, I always had osteoarthritis so I can not attribute joint & muscle pain to taxol. Taxol was prescibed as pallative, but I now am almost normal, scan show the cancer has stopped progressing and bone mass in regenerating. The results of Taxol have been nothing short of miraculous. Prior to treatment I required vicodin every three hours, I have reduced my pain medication to every 6 hours and often forget to take the drugs. Prior to Taxol I could not stand or sit erect for more than 15-20 minutes due to pain in neck and spine. I am now remodeling my home, washing cars and driving again. My diagnosis in Oct was terminal, but I now think I may again have a future. M 66 2.5 months
6/4/2008
 4  breast cancer After my mastectomy, I did AC-T chemotherapy. 4 treatments of AC, then 4 of TAXOL. Treatments were intraveinous, once every two weeks. With the TAXOL, I got severe pains in the legs two days after the treatment. I took one ARCOXIA pill - and was pain free for the next 2 weeks. This happened for all four treatments. Hope this works for you too !! M 63 60 days
1X AN
10/30/2010
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 4  Stage 4 lung cancer Slight neuropathy and swelling of feet; slight tingling of fingertips; almost complete hair loss including all body hair. Side effects not suffered include nausea, intestinal problem, heart or kidney problems. I have had 20 injections (each lasting 2 hours) of Taxol in the last 26 weeks. I take 3 weeks in a row, skip a week, and then start another 3 weeks of injections. Currently I will be skipping 3 weeks (impending cataract surgery) and resuming weekly injections on June 13th. I have found that this skipping allows my body time to rebuild and not leave me completely drained and weak..The day of and the day after chemo are my coming down from the steroids days. Days 3 and 4 after chemo are generally my "don't do anything" and rest days. Days 5 and 6 are my "normal" and productive days. The latest CT scan shows that Taxol has reduced the cancer mass in my lung to one-third the size it was before Taxol. Prior to Taxol I was on Carboplatin every 3 weeks, however this chemo still allowed for the effusion to build up in my lung. Since starting on Taxol last November I have not had the need to have my lung drained of effusion (thoracentisis). As a comparison, between my diagnosis in June 2011 and my last thoracentisis in Nov 2011, a total of 11.3 liters of fluid at 7 different times were removed from my left lobe. M 66 26 weeks
180 MG 1X W
5/17/2012
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 5  Breast Cancer Fatigue. Taxol helped save my life. I was Stage 2B when I started treatment with a tumor 4 1/2 cm in size. Opted for neo-adjuvant chemo in the hopes of saving my breast. Started with dose dense A/C for four treatments every other Tuesday and ended with dose dense Taxol, four treatments every other Tuesday for a total of 16 weeks of chemotherapy. Because of the positive response to chemo my tumor was shrunk to 1.1cm and removed successfully. Followed with daily radiation for 7 weeks. Six years post treatment I am completely disease free. F 58 8 weeks
2X M
3/6/2013
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 5  breast cancer I experienced severe myalgias & neuralgias while on the drug, plus neuropathy in hands and feet. The neuropathy in my feet is still there to a lesser degree after 5 years. I have experienced a loss of cartilage at my great toe and foot joints - something the orthopedic MD says he does not frequently see in "someone like me." It is extremely painful and there is really not much you can do about it, except surgery to fuse the toe. I am concerned that the cartilage damage has been caused by the Taxol and that other joints will be affected. Has anyone else experienced this???? F 8 weeks
11/30/2005
 5  stage I grade 3 triple negative BC intermittent very mild neuropathy, some stumbling, but not too bad. a little fatigue, but not too bad. After the Epirubicin and Cytoxan, the Taxol is wonderful I think the pre-meds are the primary cause of my tiredness and malaise for a day or two after the treatment. my WBC and RBC counts are low, but staying constant I am ravenous due to the dexamethasone pre-med, but try to eat lots of proteins to keep my blood counts up. I take a couple tablespoons of blackstrap molasses every day, and I'm convinced that that is helping with the blood counts. F 49 6 weeks
12 weeks 1X W
5/15/2011
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 5  MD Anderson I am in my 9th week of Taxol treatments and have not experienced any major side effects. (oh, except for my hair thinning out) i take my treatments on Saturday mornings so I have the weekend to rest. I still work full time in upper management. Everyone responds differently to treatment. F 40 9 weeks
1X W
2/22/2011
 5  BC Stage3A Hair loss, nausea, neutropenia and anaemia. I continued working (office), but had to quit the gym, which I resumed 3 months after the last chemo and surgery. I had a giant tumor, which after Taxol reduced to 10.5 cm but had free margins. I'm currently finishing my rads and taking Armidex. Apart from the anaemia and neutropenia, which required some extra care the treatment went smoothly. 3 months after I still have a bit of neutropenia but my quality of life is OK, besides the doctor says I'm cancer free! F 48 6 months
1X O
2/5/2010
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 5  breast cancer fatigue I am on weekly taxol for twelve weeks, just finished my fourth. So far my only side effects are some fatigue after the decadron steroid wears off, and a little stomach acid so I avoid spicy foods. No hair loss yet, although I'm expecting it. No neuropathy or joint pain as others have described. No other side effects. I was on AC for four cycles before and it was horrible. Compared to that, this is a walk in the park! F 48 12 weeks
6/19/2009
 5  stage 3 breast cancer I have been off taxol for 1 year.The right leg is inflammed and has spasms,with pain.Right down to the big toe.I used to enjoy dancing and I do,nt feel light on my feet.I won,t give up yet! Yes,I sat most of the year and I,m better than 6 months ago when I had to hold on to a shopping cart in the store and if i let go ,I couldn.t make it to the car.I take the super greens ,I eat lots of green salads,drink detox teas.Your bodies must become more alkaline than acidic.Acid foods cause joint pain right down to cancer.Meat,dairy,sugar,white flour,coffee ect.are to be eaten sparingly, if not at all! Try salads of spinich,other hearty greens ,avacado cucumber,lime juice.Don.t forget berries,cherries,strawberries.olive oil,nuts fish,omega oils,vitimins too. F 54 2 months
3/10/2008
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 5  Stage IIIb ovarian cancer I began taxol and carboplatin following my surgeries, partial hysterectomy when cancer was found, then removal of my ovaries (both cancerous), debulking of largest tumors in the abdominal/chest cavity, and staging 3 weeks following my initial surgery.I took 6 treatments of taxol and carboplatin, I think every 5-6 weeks, and was in remission on PET scan upon completion of treatments.I did have problems with decreased white cells and had injections daily for 5-7 days following chemo to boost my white cells (which added more extreme bone pain).I took scheduled doses of Phenergan for 3-4 days following treatments to control nausea.I had flushed face, shoulders, and chest on the second day of treatment (which I was told was a side effect of the steroids given with treatment to prevent side effects of the chemo).On day 2 following the chemo I had severe bone and muscle pains and learned to take scheduled doses of Lortab the day of treatment for 3-4 days to keep pain under control.About 4 day Started just taxol 2 months later.The day of my 3rd treatment they discovered my heart rate was 144, treatments were stopped.I went through an extensive cardiac workup.Question if chemo caused the problem,I had never had trouble before.Treatments were resumed.I have now had 9 treatments/3 more to go.CA125 levels are 5-6.Have had no problems with low white cells just on taxol.Treatments 8&9 I have noticed worse side effects for longer period of time with bone, muscle, nerve pain.Also have extreme pain both knees,trouble walking after sitting for a prolonged period of time.Walking does seem to ease these problems but I still move slowly.I was a very on-the-go,energetic person before all this.My energy level is now zero.I find it difficult to accomplish half of what I used to.I work 37 hrs. a week, barely get through it & and take care of my pets.Have had a 50+ lb wt gain from the steroids with treatments,fluid retention.Have bouts of depression, back pain (have DJD but back pain F 54 15 months
11/10/2008
 5  Stage 1 Uterine cancer Hair Loss / temporary very mild neuropathy I began Taxol on a weekly basis (3 weeks on 1 week off) in Nov. 2008. Due to thinning I finally cut off my hair the middle of Jan. 2009 and went to a wig. I have not had any of the normal side effects - no nausea, fatigue, body aches. I work 32+ hrs. a week (75% on my feet)and have not missed a day of work. I take myself to and from treatments. My treatment effectiveness is being monitored by CT scans and CA125 blood tests for tumor markers. Both show my tumors are rapidly shrinking. I was determined not to let Taxol get the better of me. F 61 9 weeks
1/19/2009
 5  2nd bout with cancer Dizziness, bowel disruption, tingling in extremities, muscle aches,incontinence,malaise.loss of body hair, metallic taste. horrific side effects This chemo was worse than the first time. I was unable to function for 5 days after sessions. But, although I said I could not handle another dosage, the reality is that I am alive. Three months after the last dosages, feet and hands still ache. I fell and fractured some ribs during a dizzy spell,so am still using a cane. But I am alive and am enjoying life. My hair has begun to grow again. F 72 6 times
11/24/2007
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 5  mastectomy/breast ca tingeling feet/hands-slight black fingernails-tired feeling-red rash on face from decadron(spell)taken night before.. took the once per week dose..did not loose eyebrows like everyone said I would..hair started growing back fast..still tingeling in feet/hands after last dose last week F 54 12 weeks
8/13/2007
 5  Metastatic breast cancer Fatigue was the only important one; one day mostly in bed for each weekly cycle. My hair fell out, but who cares? None of the nausea/vomiting I've experienced with other chemo drugs. No peripheral neuropathy. Only very mild and occasional joint pain. I had 16 weekly doses of Taxol over about 6 months; 3 weeks on 1 week off with a long break over Christmas due to going on holiday rather than medical considerations. Having weekly doses seems to reduce the side-effects without reducing the efficacy (there is scientific evidence for this, not just my opinion). It was palliative in intent, and it has worked ie my various tumours have shrunk in size. F 44 6 months
3/12/2007
 5  breast cancer Side effects of Taxol were more severe than those experienced from Adriamycin/Cytoxin. With Taxol, slight numbness in fingertips and slight detachment of fingernails. Fatigue. Took glutamine and high-dose vitamin B6 to minimize side effects. Had GREAT result with first four A/C treatments. Tumor was further diminished by four treatments of Taxol to the point that my last treatment was optional. Took it anyway. I started chemotherapy very shortly after diagnosis in order to save my breast. My doc said neo-adjuvant therapy works in approx. 70% of patients. Glad I yook my chances! Chemo is no walk in the park, but it does help save lives (and breasts!) F 52 8 weeks
11/15/2006
 5  pleural mesothelioma, The side effects quite predictable.Day one and 2 fine, symptoms appeared on day 3 lasting 4 to 5 days. Numbness in feet,hands constantly.Each session it seems more pronounced.Red face on day 2 and body rash for a few days.A HUGE amount of pain throughout body FOR A GOOD 4 TO 5 DAYS.Knees and hands of late have permanent discomfort.Joints in hands feel arthritic and are swollen. My CA125 LEVELS HAVE DROPPED PROMISINGLY WELL.Have had 6 Taxol sessions every 3 weeks and started another set of 3 every 4 weeks.Last one in 3 weeks time.Hair loss, but fabulous wigs to be found.Eyebrow and eyelash loss.Chest pains on 8th dose of Taxol.Nauseau each time but abated with drugs,Tastes different.Tiredness.Have found excercise( walking)as soon after as possible improves my condition.Wonder if I will ever get feeling in my extremeties again? Debilitating side effects , but worth it to drop my ca125 levels. F 46 8 months
4/24/2007
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 5  Breast Cancer Stage IIIB Neuropathy in hands and feet; rash on my face, progressive memory problems/light headedness; weight loss/loss of appetite; loss of hair on entire body I am sure this is what helped me to have complete response; more and more research is showing weekly dose is the way to go; I did it because of side affects I had with AC; I still have back pain and numbness 3 months later but I show no cancer on my scans and path report F 53 12 weeks
8/29/2009
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 5  Stage I Breast Cancer Some fatigue, short-term memory loss (but not enough to affect my work), very upset stomach for three days following treatment, diarrhea/constipation and loss of menstrual cycle. NO mouth sores, joint pain, nail problems, neuropathy, or total hair loss (just some thinning of my hair, but not my facial or bodily hair). I was prepared for the worst, but found Taxol to not be as bad as I thought it would be. I just finished my last dose on August 13th. I participated in a clinical trial where I received Taxol weekly for 12 weeks. I think the data is showing that a lower dose administered weekly is easier on patients. At least is was for me. I was able to work every day but the day I got the Taxol. The worst symptom for me was my stomach/bowels. I didn't lose my hair. It continues to fall out, now 3 weeks post Taxol, but I never lost enough that I had to wear a wig. I did, however, have to have high does of Decadron because I had a severe reaction to my first infusion. After that (which wasn't fun), it was faily unremarkable. I have three children under the age of 4 and was able to care for them without them ever knowing I was sick. So, I recommend Taxol, and definitely given weekly over 12 weeks. Hope this helps :-) F 37 12 weeks
9/6/2009
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TAXOL  (PACLITAXEL):  Paclitaxel is used to treat various types of cancer. It is a cancer chemotherapy drug that works by slowing or stopping cancer cell growth.   FDA Approval Date: 1992-12-29 (Sources: U.S. Centers for Medicare Services, FDA)

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