TAXOL Reviews (PACLITAXEL)

Average Rating: 3.5 (99 Ratings)

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TAXOL  (PACLITAXEL):  Paclitaxel is used to treat various types of cancer. It is a cancer chemotherapy drug that works by slowing or stopping cancer cell growth.   FDA Approval Date: 1992-12-29 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR TAXOLCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Breast Cancer I finished chemo six months ago, and I have had lingering side-effects from Taxol that make me regret having taken it for primary bc. I have very bad pain in all my joints (especially shoulders, elbows, knees, back). I also have a great deal of muscle pain in my arms and legs. I am 44 years old and I walk like a ninety-year-old. It is very hard for me to get around. My immune system is shot too: I have on-going shingles, sore throats, and mouth sores. No one told me my quality of life would diminish so severely. Question your doctor about future quality of life issues before you begin Taxol. F 44 4 times
9/25/2005
 5  breast cancer I experienced severe myalgias & neuralgias while on the drug, plus neuropathy in hands and feet. The neuropathy in my feet is still there to a lesser degree after 5 years. I have experienced a loss of cartilage at my great toe and foot joints - something the orthopedic MD says he does not frequently see in "someone like me." It is extremely painful and there is really not much you can do about it, except surgery to fuse the toe. I am concerned that the cartilage damage has been caused by the Taxol and that other joints will be affected. Has anyone else experienced this???? F 8 weeks
11/30/2005
 5  breast cancer Side effects of Taxol were more severe than those experienced from Adriamycin/Cytoxin. With Taxol, slight numbness in fingertips and slight detachment of fingernails. Fatigue. Took glutamine and high-dose vitamin B6 to minimize side effects. Had GREAT result with first four A/C treatments. Tumor was further diminished by four treatments of Taxol to the point that my last treatment was optional. Took it anyway. I started chemotherapy very shortly after diagnosis in order to save my breast. My doc said neo-adjuvant therapy works in approx. 70% of patients. Glad I yook my chances! Chemo is no walk in the park, but it does help save lives (and breasts!) F 52 8 weeks
11/15/2006
 4  ovarian the main side effects I have had is being somewhat tired and weak feeling, food tastes and dehydration the first few days after treatment. I received 8 cycles in 2005 and now am near the end of 6 cycles. I have experienced no neuropathy during or after either of these cycles. And taxol has decreased my CA125 down to normal each time. My doctors are amazed at how well my body is handling treatments. Frankly, I am too. F 44 4 months
2/27/2007
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 5  Metastatic breast cancer Fatigue was the only important one; one day mostly in bed for each weekly cycle. My hair fell out, but who cares? None of the nausea/vomiting I've experienced with other chemo drugs. No peripheral neuropathy. Only very mild and occasional joint pain. I had 16 weekly doses of Taxol over about 6 months; 3 weeks on 1 week off with a long break over Christmas due to going on holiday rather than medical considerations. Having weekly doses seems to reduce the side-effects without reducing the efficacy (there is scientific evidence for this, not just my opinion). It was palliative in intent, and it has worked ie my various tumours have shrunk in size. F 44 6 months
3/12/2007
 3  breast cancer Mostly just a little tired the day of and after taking taxol. Very little nausea. At the end of the treatments however, I experienced severe leg cramps, and neuropathy in hands and feet. 2 months later and still walking like Im eighty---always had strong legs and knees before---hope I get that back. F 45 3 months
3/21/2007
 1  Breast Cancer Taxol was horrific. This was my second primary breast cancer so I couldn't use Adriamycin again. From the very first treatment I could barely walk. Began treatment in May 06 and finished in August. I thought my symptoms would get better when I finished, but it only got worse. I have always been active and now have to struggle to walk or even move on some days. I am 43 and I walk like my grandmother. Feet, hips, shoulders and hands hurt terribly. F 43 4 months
4/2/2007
 5  pleural mesothelioma, The side effects quite predictable.Day one and 2 fine, symptoms appeared on day 3 lasting 4 to 5 days. Numbness in feet,hands constantly.Each session it seems more pronounced.Red face on day 2 and body rash for a few days.A HUGE amount of pain throughout body FOR A GOOD 4 TO 5 DAYS.Knees and hands of late have permanent discomfort.Joints in hands feel arthritic and are swollen. My CA125 LEVELS HAVE DROPPED PROMISINGLY WELL.Have had 6 Taxol sessions every 3 weeks and started another set of 3 every 4 weeks.Last one in 3 weeks time.Hair loss, but fabulous wigs to be found.Eyebrow and eyelash loss.Chest pains on 8th dose of Taxol.Nauseau each time but abated with drugs,Tastes different.Tiredness.Have found excercise( walking)as soon after as possible improves my condition.Wonder if I will ever get feeling in my extremeties again? Debilitating side effects , but worth it to drop my ca125 levels. F 46 8 months
4/24/2007
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 3  breast ca- mastectomy wake at 3am nite of treatment and next nite after treatment..no going back to sleep after that...day 3 4 5 very tired but have to work or no insurance to pay for taxol! Makes you very tired third thru fifth day treatment..Red face second day treatment..some body aches..mouth sores..hair loss..my fingers and feet have had no problems like others have talked to....some mornings I have to set my clock an hour early to take Tylenol. The body pains are very bad in the morning getting out of bed easier if taken Tylenol earlier..I take the arthritis tylenol which lasts most of the work day. Sometimes feel feverish too... F 53 6 weeks
6/20/2007
 4  bc Numbness/tingling in toes and fingers; also experienced some pain in joints. Lost any and all remaining hair (eyebrows, eyelashes, nose, arms, etc.) But worth it to save my life. Had four rounds of A/C and four rounds of Taxol. Finished last taxol treatment two weeks ago; tingling hasn't gotten worse but it hasn't gotten better either. I walk everyday which helps immensely. Also take B6 supplement as suggested by my oncologist. Also noticed that a foot massage at night helps me sleep without interruption. F 42 2 months
8/3/2007
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 5  mastectomy/breast ca tingeling feet/hands-slight black fingernails-tired feeling-red rash on face from decadron(spell)taken night before.. took the once per week dose..did not loose eyebrows like everyone said I would..hair started growing back fast..still tingeling in feet/hands after last dose last week F 54 12 weeks
8/13/2007
 3  Breast CA Felt like a train wreck about 3 days after my first dose. I had done 4 doses of A/C and had started back as hospital nurse after the A/C. Thought the chemo was a piece of cake. thank God for Emend. I have terrible joint and achy pain that I never had before since the chemo. I guess you should say shut up since your'e still alive--Some days it aches so much I wonder. Back working full time F 53 8 weeks
9/20/2007
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 2  treatment for breast cancer I had two bouts of breast cancer, early 2004 and late 2005, different kinds each time, so I got the double whammy with chemo less than two years between sessions. The second time I got Taxol. I had terrible leg pain (hips, knees, feet, shins, heels) and shoulder pain. Only people who have been through this know what I mean by "leg pain." It sounds so petty. This got worse and worse even after the treatment ended until I was walking with a cane, couldn't go up and down stairs, and was afraid to step off a curb. Further tests showed severe and rapid deterioration of the left hip joint and left shoulder joint. I'm only 57 and had to have my left hip replaced in April 2007 and my shoulder joint replacement is scheduled for Dec. 2007. Both the arthritis specialist and the bone specialist say they have never seen such rapid deterioration, especially of the shoulder, for any naturally occuring reason and they suspect it's from the chemotherapy, probably the Taxol. I will say, the hi As far as being satisfied that Taxol helped me, it's something we'll probably never know. So looking back I probably would have taken it anyway; better to be alive to complain. But the side effects were very severe in my case. F 57 3 days
11/2/2007
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 2  Breast cancer recurrence 3 days after treatment felt like I was hit by a bus. Could not stand up, severe leg and foot pain made it impossible to stand. About 1 week after each treatment, I started to feel fine again. Its been 2 months since last Taxol treatment and I feel like my legs are crippled from the knees down. If I sit for longer than 10 minutes I have so much pain I can hardly stand. Also leg pain when on my feet. I am only 49 years old and I feel like I am 80. I was always extremely active. Hope this does not last forever. F 49 4 days
11/13/2007
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 5  2nd bout with cancer Dizziness, bowel disruption, tingling in extremities, muscle aches,incontinence,malaise.loss of body hair, metallic taste. horrific side effects This chemo was worse than the first time. I was unable to function for 5 days after sessions. But, although I said I could not handle another dosage, the reality is that I am alive. Three months after the last dosages, feet and hands still ache. I fell and fractured some ribs during a dizzy spell,so am still using a cane. But I am alive and am enjoying life. My hair has begun to grow again. F 72 6 times
11/24/2007
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 2  BC Pain entire body, unable to think or concentrate, tingling and pain in feet and fingers,leg and feet cramps, weakness and pain in hips, unable to walk very far, off balance and need help to go up and down stairs. Toenails and fingernails separating from nailbeds and shriveling up to small unsightly nails. I finished taxol in June 2007, it is now December 1,2007. I still have all these symptoms plus my back has broken 3 times this summer due to chemotherapy and osteoporosis. I now have added pain and am very limited in what I can do. I don't know if I could recommend this drug or not, I have not been told whether it has helped me. I am in physically worse shape than I have ever been and was always a very active person. The only thing I know to do is wait and hope it gets better. But (am having trouble thinking of the word) yes, depression is always there. F 59 3 months
12/1/2007
 4  Breast cancer after Hodgkin's Disea This is my 2nd time with chemo, much worse this time, especially during & after Taxol, lots of pain in back, knees, feet, hands & shoulders, feels like severe arthritis, can barely walk worried I may need a wheel chair soon to get around, walking helps, but when I stop walking, I get stiff and pain returns Kind of regret taking Taxol because my quality of life has diminished, I no longer enjoy going out or shopping because I am in so much pain. I see 90yr olds who walk better than I do. My worse fear is that it is only going to get worse as I age, will try any medication to alleviate pain, Lyrica didn't help. F 40 6 days
12/22/2007
 5  metastatic laryngeal cancer to lung 1x weekly for 3 weeks then 1 week off ,just finished week 3, hair is thinning out mild bone pain and moderate fatigue. 15 more treatments ,hope it doesn't get much worse!! M 57 3 days
1/29/2008
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 4  stage 1 breast cancer Strong metallic taste in my mouth. Slight nose bleeding. Taking Taxol every week for 12 weeks. Have 6 to go. Side effects not near what expected. Hair is growing back from Adrymiacin and Cytoxan. Don't have any joint pains whatsoever. F 52 12 days
2/12/2008
 3  Breast Cancer Went through taxol 1x a week for 12 weeks. My side effects were minimal at the time but then NERUOPATHY set in. Matter of fact I didn't recieve my last TX because of the numbness in my feet. I suppose since Taxol saved my life I have that to be thankful for ,but the side effects are devistating my neruopathy is getting worse as time goes on and im 5 months post chemo. I have had to change positions at my job to a desk job from a job that I was on my feet all day. The weekends suck cause I reep the repracutions of being on my feet all day all week long. Yes and Im 45 and feel like a 90 yr old woman. My quality of life sucks!!!! F 45 12 weeks
2/24/2008
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TAXOL  (PACLITAXEL):  Paclitaxel is used to treat various types of cancer. It is a cancer chemotherapy drug that works by slowing or stopping cancer cell growth.   FDA Approval Date: 1992-12-29 (Sources: U.S. Centers for Medicare Services, FDA)

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