LAMICTAL Reviews (LAMOTRIGINE)

Average Rating: 3.4 (1917 Ratings)

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 ANTICONVULSANTS

 Type: Rx Drug

  

LAMICTAL  (LAMOTRIGINE):  Lamotrigine is used alone or with other medications to prevent and control seizures. It may also be used to help prevent the extreme mood swings of bipolar disorder in adults. Lamotrigine is known as an anticonvulsant or antiepileptic drug. It is thought to work by restoring the balance of certain natural substances in the brain. This drug is not approved for use in children younger than 2 years due to an increased risk of side effects (such as infections).   FDA Approval Date: 1994-12-27 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by length of time drug was taken longest to shortest.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on LAMICTAL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR LAMICTALCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Bipolar 1 Minor fatigue early on, body pains in the beginning and at each dose increase - if you have a minor backache the dose increase will cause it to be a major backache, but only for a few days. Works very well for me. For about 8 years I was on Seroquel and Depakote and gained tons of weight - either extremely hungry or tired. On Lamictal I have been able to adjust to a very healthy lifestyle and have lost over 100lbs. With Lamictal I have attained the most stability I've ever enjoyed. M 38 1 years
8/2/2009
 5  mood stabilizer Occasional spaced out feeling. Greater sensitivity to alcohol. At 37.5mg the drug has kept my anxiety and depression under control. At 50mg its more effective, but its harder to concentrate and I feel somewhat detached. Otherwise this has been by far the best drug I've been prescribed for mood issues. Its a breath mint compared to Lexapro and others I've been on. M 1 years
9/6/2008
 5  Bipolar II Sore muscles (went away). Memory problems- really bad at first, but has gotten much better. Still a little absentminded, but I'm okay with that. More forgetful especially when tired. Insomnia- but I have always had it, so I don't know if this makes it worse or not. Acne-unfortunately, that hasn't cleared up- now I see a dermatologist. Like someone said earlier- it has saved my life. I wasn't able to really see just how sick I was before until I had taken Lamictal (and I did feel it fairly soon after I started- maybe a week to 10 days). I've been pretty stable on it for the most part, except for during my period- I doesn't work as well during that time and that sucks.I currently take 300 mg per day and have for about a year and a half. It hasn't felt as effective for the past couple of months, but I see my p-doc today and she might titrate me up (she says there is room to do that)or add something. On the whole- sooooo worth it ! F 39 1 years
9/30/2008
 5  Bipolar SHORT-TERM MEMORY LOSS- I often forget what I did just the other day/have to be reminded of conversations and things that I said /Have resorted to writing down anything of importance so that I don't forget. NIGHT SWEATS-- I have night sweats every night and my sheets/comforters end up soaking wet. I have started to sleep on a terry cloth towel so I don't have to change my sheets so often. STUTTERING/LOSS OF WORDS-- I am an interpreter, so for my profession, it is crucial that I possess the verbal and language skills necessary to perform my job well. Since taking Lamictal, I find that I have a difficult time getting the words that I am thinking to come out of my mouth. I find myself using word substitution. For example, if the word "jurisdiction" is too difficult for me to say, I will replace it with " area". I keep the concept intact but have had to dummy-down my spoken vocabulary. I stutter or my brain won't let my mouth say the words. I a Ok... so would I stop taking lamictal due to the side effects? Not in a million years! Never! I feel like my best self--- how I used to feel before my illness took over my life. My relationships are better-- healing every day. I feel balanced, smooth, and even. I love my little pill. My family and loved ones do too! F 42 1 years
6/13/2008
 5  Bipolar II Increased anxiety, vision focus slowed. Really helped my irritability and mood, but I noticed that my vision was getting less sharp and it took me longer to change focus from near to far. I began to have a lot of trouble driving at night. M 39 1 years
100
5/14/2019
 5  Major Depression Disorder Extremely effective. Brand Name and TEVA Only. Be careful of CADISTA Manufacturer (Round White Pill J 247) It's Horrible. Does not work. Manufacturer will swear its the same active ingredient, but we all know the delivery system is just as important. (Can't deliver it effectively, the body can't use it) Other Generics: TEVA works fine. No problems Works using new Glutamate NMDA Receptor research. Field is very promising. If you had no luck with SSRI's (Prozac,Zoloft, etc), or the new SGA's (Abilify, Quetiapine), then give this a try; it's worth the effort. It's entirely new technology. I feel normal again. You must titrate SLOWLY. Notice Comment about CADISTA, a generic brand, (Do not take - Refuse to pharmacist; demand TEVA or Brand Name) M 49 1 years
150 1X day
5/14/2015
Email
 4  Seizure I had my first and only seizure a few months after brain surgery. I was put on Keppra and felt irritable and easily agitated. They switched me to Lamotrigine 200mg twice a day. It's worked in preventing any more seizures but I also feel it's dulled my emotions- but more my happiness. I still cry and feel sad emotions but when I get happy, it's like there is this ceiling to my feelings that suppresses how excited I feel. I don't know if it's timing- 9 months after surgery, Covid became a thing, so I wonder if it's a mix of post-surgery emotional recovery, pandemic life, or medication. F 32 1 years
200 2X day
5/2/2021
 4  mood disorder tiredness, MAJOR MEMORY and cognition problems I am so in love with this drug but the fogginess is getting to be a real problem. The other day I was driving to drop off a very important loan package for our business. I needed to stop at the auto store for something and walked out and completely forgot about this most important thing. If my husband hadn't called I think it would still be in my back seat. May have to give it up even though it has made me really stable. Am on Wellburtrin (150) too and all depression is gone. I have ADD and used to take Adderall--maybe this will help the fogginess? Anyone had success with that combo? M 40 1 years
4/6/2009
 4  Bipolar Depression w/ Anxiety I have had none of the side effects that I've seen online, except stomach ache and heartburn, which has caused me to lose weight. That might be good for some, but I'm already thin. Other than that, this is the only medication that has worked for me in the past, so I am trying it again. It has also helped with focus, which is a bonus because I also have adult ADD. F 43 1 years
200
8/26/2014
 4  Bipolar II Hair thinning, weight fluctuations, short term memory loss. I really despise the memory problems, but this has been the best drug so far. 1 years
3/5/2008
 4  depression weight loss, feelings of being full easily and not getting hungry, but that subsided. Hair loss at first, but it grew back (that lasted about 4ish months) Well I gave it a four because its a good drug I took it actually because I thought I was Bipolar. But I'm sure it will work miracles for those who are. I now take Prozac also and my life is the way it used to be. I know what its like to go through such a hard mental/physical problem. Never give up!! Your life is worth it. Even if this medicine dosn't work their is something out there for you! F 16 1 years
9/1/2007
 4  Epilepsy Weird vivid dreams, hullacinations of black bug like dots (only 3 times), mood swings, slower thinking and talking, feel hot more than usual, dizzyness,nausa and short term forgetfulness and I get tired easly. The first two to three months I had terrible side effects, its a good thing I coundn't drive because Im sure I would have caused an accident! The hullacinations were the scariest part of getting used to the medication but for the most part the only side effects I still have are dizzyness, and slower thinking. Im still tired more than I was before I started the medication. This medication has controlled my seizures but I I forget my medication once or twice I have more seziures that I did before I started Lamictal. I dont like the side effects but they are better than having seizures. The only thing I worry about is taking this while Im pregnant. Is ther any one who has taken Lamictal while pregnant? I would like some feedback if possible. Thanks. F 23 1 years
3/31/2008
Email
 4  BIPOLAR 1 AND ANXIETY OUT OF BODY EXPERIENCE WHEN NOT TAKEN AS RX'D.. REALLY HELPS WITH MY EXTREME MOOD SWINGS BUT MAKES ME A LITTLE CRAZY AND HYPER AT TIMES. LIKE JUST YELLING AND ACTING SILLY.. M 33 1 years
5/9/2008
 4  Depression/Anxiety Practically none. Very vivid dreams. Occasional shakes when it would wear off. Saved my life when I had to abandon the entire SSRI class of drugs! This drug changed my life. It was the 5th medicine I tried and had fantastic success! I have started hormone therapy (to try to undo 10 years of synthetic birth control damage) and it has helped me while trying to get balanced. HOWEVER ... I think I have to stop now and go the rest on my own, because based on what I have been researching, it must be lowering my Estrogen level and working against my hormone replacement! Thanks for all of your comments, you have helped me take another step on my journey to being well and normal and happy! F 32 1 years
1/21/2009
 4  Mood Stabilizer/Depression Dry Mouth, Sleep problems, Short-term memory loss, Trouble getting words out I am on 300mg of Lamictal and 60mg of Cymbalta, I have a tough time sometimes distinguishing what side effects are from what, but I just recently increased Lamictal from 200mg to 300mg and am noticing severe dry mouth, trouble sleeping, short term memory loss - I have to write everything down or I completely forget, and I noticed that I am sometimes having a tough time getting words, I am usually a pretty fast talker, but lately am almost tripping over my words, its like my brain can't keep up with my mouth. However, the side effects are minor compared to the stablizing of my mood. F 23 1 years
12/2/2008
 4  seizure loss of balance which has gotten worse after a year of useage/also some irritability this drug seems to be doing its job and I can live with the side effects M 60 1 years
8/7/2007
Email
 4  BP For the last couple months I've had a clenched jaw. I didn't consider that it might be a side effect until just now. After reading the comments, I recognize: bleeding gums, excessive sweating, word loss, clumsy typing, spelling, can't recall names on demand, joint pain. I've unconsciously been adjusting to all these things without recognizing Lamictal as the thread. I feel kinda dumb. The word loss, typing, and spelling bother me most as cognitive side effects. The jaw clenching is the only physical reaction the makes me uncomfortable. Lamictal is my only consistent med. I take 300 mg at night and it has stabilized my life and I am so grateful. I was such a skeptic at first. I resisted meds for years and years. To have something that works--even if "normal" is annoyingly normal sometimes--I value it more than the rollercoaster. F 34 1 years
5/4/2007
 4  Bipolar Disorder When upping the dosage I had a headache for less than a week each time which went away. I notice fatigue but this could be caused by any number of things and I can not say it directly correllates to the Lamictal. Memory worsened. Unfortunately I do feel as if it simply dulls me down, which I suppose is the idea. Less lows=less highs. While I do feel somewhat dumbed down and think it has affected my memory, it is important to remind myself that feeling a little numbed is certainly preferable to wanting to die due to severe depression. You have to take the good with the bad. Overall, Lamictal probably saved my life. I've read a lot of negative feedback about it, and everyone is certainly different, but it has helped me regain a level of normality and to regain much more of myself than I had feeling depressed nearly every day for far too long. M 21 1 years
7/26/2007
 4  Mood Disorder NOS, Anxiety Headaches initially, feeling lethargic anytime my dosage was increased or decreased...It worked well when I was on 400mg. I'm currently down to 150mg., and I have been having distress coming off of it. We aren't sure if it's because I'm on birth control or from the Lamictal decrease. Both my Effexor and Xanax have had to be increased. I think it's a good drug. I had very little side effects from it, and I am one of those people who usually has side effects no one else does. Be careful raising and lowering your dosage. I'm coming off the drug right now, and my doctor is questioning if it was the right thing since my anxiety and panic have increased and I've been depressed. F 26 1 years
6/5/2007
 4  Bipolar III roaring in ears, confusion, memory loss, feeling that my brain was shaking in my head (really), vivid dreams, potentiates alcohol (nothing else has ever given me a reaction, and I only drink a glass of wine or two. Not any more!) As far as working in conjunction with my Paxil CR, it is great. The lift is good. The cost of the drug is abysmal, as I do not have health insurance. Missing a day or two is horrible. I wonder about my diagnosis sometimes because the only time I have ever had manic episodes (and they weren't that severe) was when I was on and off meds, trying to find something that worked. F 46 1 years
3/23/2007

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