LAMICTAL Reviews (LAMOTRIGINE)

Average Rating: 3.4 (1917 Ratings)

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 ANTICONVULSANTS

 Type: Rx Drug

  

LAMICTAL  (LAMOTRIGINE):  Lamotrigine is used alone or with other medications to prevent and control seizures. It may also be used to help prevent the extreme mood swings of bipolar disorder in adults. Lamotrigine is known as an anticonvulsant or antiepileptic drug. It is thought to work by restoring the balance of certain natural substances in the brain. This drug is not approved for use in children younger than 2 years due to an increased risk of side effects (such as infections).   FDA Approval Date: 1994-12-27 (Sources: U.S. Centers for Medicare Services, FDA)

  

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More on LAMICTAL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR LAMICTALCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  schizoaffective disorder overall extreme fatigue did help with my symptoms of mood swings but 100 mg was too much for my body weight(155); could not function with such extreme fatigue (knees buckling while standing, dizziness); may return to 25 mg; am trying lithium now F 19 6 weeks
4/11/2007
 2  adjunct to antidepressant Short-term memory loss. We all misplace our keys now and then, but I began to lose track of EVERYTHING that I wasn't wearing. It was a frightening experience for me. F 65 3 months
3/9/2007
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 2  major depression along with PTSD Itching all over my body from head to feet....mostly eyes, stomach, arms, & back without rash. Nausea & made food taste horrible. Almost throwing up. Horrible nightmare that went along with the PTSD issues I am dealing with. Throat feeling like flu without it being sore (just swollen feeling) & running nose with mild temperature. Next night couldn't sleep (maybe trying to avoid the nightmares) or beause I felt so horrible the day before I didn't get out of bed. This all happened after only 2 25mg doses so pdoc dc'ed & prescribed antahistamine for reactions (allergic to benedryl, so trying atarax (vistaril). F 54
2/16/2007
 2  major depression, panic/anxiety headache, dizziness I am feeling very discouraged because it seems most are having success with drug yet I am not. Have tried many other drugs. Nothing seems to work to any great degree. I used to be a very loving, patient, good humored person but now I am moody, irritable and seem to have very little compassion for others. Can someone please tell me how long on the drug before they started getting results. I have titrated up to 200 mg and have been on that level for about 4 weeks now. If I were going to be helped by the drug, shouldn't I already started feeling better by now? M 35 50 days
2/13/2007
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 2  Depression and/or Bipolar I I just started taking Lamictal today. I started Seroquel one week ago. Was feeling like living again, but gaining weight with the Seroquel. Today first dose of lamictal, upset stomach all day. Not sure if related, but really scared after reading all the stuff that has been posted. Could somebody please tell me the difference between being depressed and bipolar. I am already overweight and have hair loss even before the drugs started. M 51 1 days
2/9/2007
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 2  Bi-polar I Weight gain, insonmia,dry mouth, urination problems I finally 'D/C'ed' both Lamictal and Lithium because I'd ask both at each visit if I was getting any better. The answer was 'no', so why bother. I'd rather tolerate hypomania and the resulting creativit, than lay there like a rock,urinating every 5 minutes,sweating through the night-sleepless, etc. M 55 2 years
1/29/2007
 2  seizure weight gain,headaches(gone after I increased to 100 mg),joint pain,loss of sex drive,fatigue,tingling and numbness in fingers,anxiety,occasional insomnia I've had one Grand Mal seizure in my life last October,the doctor did two follow up EEGs and found more seizure activity during the EEG but has no idea why I would have my first seizure at age 41(no drug abuse,no alcoholism,etc). I was on Wellbutrin for depression but stopped that a week or so AFTER the seizure. I really don't like this drug and as far as I am concerned I don't need to be on it and the side effects suck for me! The only other drug I am taking is 100mg Cozaar daily for HBP. Any other opinions on this would be welcome. M 41 31 days
1/22/2007
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 2  Bipolar Difficulty finding words, dreams so disheartening I wake up every morning dreading the day; Very depressing dreams!!! My doctor is really trying to push me into the bipolar bin. I have not seen any positive effects from this drug therefore I do not think I am bipolar. I also take Paxil and that REALY works. Will stop taking Lamictal today. M 44 6 weeks
1/18/2007
 2  mood stabilization Constant thirst--I was drinking several gallons of water a day, and would wake up in the night due to thirst. I didn't take it long enough to experience any of its intended effects. F 25 1 weeks
1/15/2007
 2  Replace Lithium, Keppra, Klonopin Cannot take more than 200 mg. without fluid retention and pain in wrists. Experiencing headaches. My psychiatrist, a good one, was under the impression that this drug was the answer to everyone on multiple medications for depression, unstable moods, anxiety, and difficulty sleeping, after 6 months of treatment. We found out that removing Lithium from my treatment after the 6 months put me right back to severe mood problems. Not sure I see any benefit from this drug. F 53 7 months
1/5/2007
 2  depression, mood swings For most folks, this is a miracle drug. For me, it seemed to not be doing much of anything. Seemed, I say, because I began having frequent blackouts, periods of intensely violent and evil feelings that I can only describe as psychopathic... utter indifference to my surroundings and the people therein. If combined with alcohol... ANY alcohol... the symptoms were much much worse. Christmas this year was passed with a psychotically violent and abusive episode that has hurt my family tremendously and that I cannot in any way recall. For most folks, the drug works miracles. I am guessing that I've been hastily diagnosed and don't really need medication at all, which is why this stuff has had such adverse effect on me. M 41 8 weeks
12/28/2006
 2  BPD, Depression, mood stabalizing Started with 25 mg now I'm on 200mg, Acne, IRRITABILITY, clumsiness, WEIGHT GAIN! (the worst, i went from 120-127 within in 1 month and im still gaining, I cant even lose any when i starve myself), Anxiety, Hopelessness, INNABILITY TO FEEL EMOTIONS, UNABLE TO ENJOY MUSIC OR ART, UNABLE TO TELL WHATS REAL FROM WHATS NOT, since i went from 100mg to 200 mg the deppresion is starting again. Side Effects are worse than benefits. F 17 1 months
11/30/2006
 2  Depression Severe night sweats (soaking wet), day-long headaches, low energy. I've been taking Celexa for a long time. But I am going through a very painful divorce right now so my doc put me on Lamictal. He's got me up to 150mg. I started noticing an hour after I take it I get a headache and get very tired and I feel like I'm trying to walk through molasses. I didn't know the night sweats were related to this med, but after reading all the other comments, I'm pretty sure that's what it's from, and so I have now decided to get off it. It's just not worth it for me. M 44 4 weeks
11/14/2006
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 2  bipolar rash when first started ,headache, anxiety irritability major anxiety.. i came off tegretol to lamictal and at first was great more clear thinking, vivid, but then the anxiety started getting worse and worse but i don't know how much was the wellbutrin or lamictal now i've switched back to tegretol without the doctor knowing after going through so much mania it was driving me literally crazy M 27
11/10/2006
 2  bipolar I 9 days into taking only 12.5 mg/day (in combination with depakote-- I was tapering off the depakote under Dr's supervision), developed itchy rash. Dr. has advised stopping Lamictal. Rash started at ankles, 1 hip, got worse overnight on ankles/feet including soles of feet. spread up both thighs. In most places it looks like very small pink dots, sometimes with a paler "halo" around the dot. (I am fair-skinned.) A few areas on my feet are blotchier. Also, I have some significant soreness/stiffness in my neck that began the afternoon before the rash started. It would be helpful if patient inserts included photos of what lamictal rashes look like. F 31 9 days
11/3/2006
 2  depression possible bipolar cold sores, headaches, achiness, sore throat, flu-like symptoms, anger, agitation, irritable,anxiety did fine on 25 mg.s for 2 weeks. when dose increased to 50 mg.s , side-effects were intolerable. dr. told me to stop meds. F 41 18 days
10/31/2006
 2  Bipolar Metalic taste in mouth, Severe gas, chronic diarrhea, dizziness with loss of balance, sinus pain with rhinitis and thick mucus that dropped to back of throat, headache, pain in fingers and hands, flu like symptoms and increased facial acne that was never an issue before, feeling completely sick, miserable and "toxic" physically. Once I increased the dosage from 50 mg to 100 mg I started to literally feel toxic. My MD decreased my dosage back to 75 mg and told me that I obviously had the flu since the dosage wasn't therapeutic level and not enough to affect an infant. I resumed the 75 mg dosage and immediately began feeling sick again with all the same symptoms. After 3 days off the medicine I began to feel somewhat normal again, so I know it was the Lamictal. This was a great mood stabilizer that left me feeling much better emotionally, but with the terrible side effects it's impossible for me to remain on the medicine. I'm discouraged and doubtful that I will ever find another medicine that was as effective at stabilizing my mood. With the adverse side effects that are reported here, I don't think the toll on my health is worth the risk. F 49 2.5 months
10/30/2006
 2  depression nausea, itchy skin, vivid dreams, tender and swollen breasts, increased menstrual pain/pms, hot flashes, sinus, feeling like I was having morning sickness, again. I will discontinue the Lamictal, I can't deal with the "female" side effects. Pdoc has kept me at 25mgs to see if I will adjust. My depression is lifting, maybe due to wellbutrion. F 46 1 months
10/17/2006
 2  Depression & Panic Attacks Explosive Anger, Mood Swings, Withdrawn from Family, Memory Problems, Increase in Weight, Vivid Dreams, Irritabilty I have been on every drug you can imagine to help me with my depression. Nothing seems to work. I am currently on 150 mg Effexor, 50 mg Trazadone, and Zantax ( when needed). I started taking Lamictal because I am still depressed. I didn't notice anything ( execpt vivid dreams) until 75 mg. At 75 mg...I started screaming at everyone and punching holes in the walls. My shrink wanted to up my dosage. I tried 100 mg for a week and things just got worse. I want to find something that helps! I have started on a 3-4 mile a day exercise program which has really helped with the anxiety but I still have depression. F 31 6 weeks
10/17/2006
 2  Chronic Severe Depression Trouble spelling words correctly (typing - used to type 100 wpm - now more like 30), short and long term memory loss, melancholia, weepiness, pee constantly, difficulty sleeping, joint pains - particulary knees, fingers, and shoulders, muscle aches, itchiness in scalp, neck and shoulders, flatulence, bo, mood swings - hair trigger irritability in some instances, blurred vision -in episodes, itchy eyes, insomnia, not feeling rested, crash around 5 or 6 in the evening (take it in the mornings when I first get up). On the bright side, I felt great the first month on this drug, but as I started increasing the doses, I started feeling worse. M 43 5 months
10/4/2006

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