MACROBID Reviews (NITROFURANTOIN; NITROFURANTOIN, MACROCRYSTALLINE)

Average Rating: 1.7 (1814 Ratings)

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 ANTISEPTICS,URINARY TRACT

 Type: Rx Drug

  

MACROBID  (NITROFURANTOIN; NITROFURANTOIN, MACROCRYSTALLINE):  This medication is an antibiotic used to treat bladder infections (acute cystitis). It works by stopping the growth of bacteria. This antibiotic treats only bacterial infections. It will not work for viral infections (such as common cold, flu). Using any antibiotic when it is not needed can cause it to not work for future infections. This medication should not be used in infants younger than 1 month old (see also Precautions section). This drug should not be used to treat infections outside the bladder (e.g., kidney infections such as pyelonephritis or perinephric abscesses).   FDA Approval Date: 1991-12-24 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on MACROBID: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR MACROBIDCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  Bladder Infection Mild stomach ache with ocassional stomach cramps, mild to moderate fatigue. Was prescribed Nitrofurantoin Mono/Mac, the generic form of Macrobid for an acute bladder infection that developed 3 weeks after being operated on for bladder cancer. Also had to have a stint put in my bladder to protect the site where the cancerous tumor was removed during the same surgery. Pain and nausea from the pressure of the stint in my bladder since the surgery 3 weeks ago has been indescribeable and goes well beyond the threshold level of 10 on a 1 to 10 scale for pain & suffering. Have somehow survived it all so far and the stint will finally be surgically removed 5 days from now IF THE MACROBID CLEARS UP THE BLADDER INFECTION IN TIME! So, I'm really counting on the Microbid to do what it is supposed to do...otherwise, surgery to remove the stint will have to be postponed until the bladder infection clears up. My Macrobid dosage is 100 mg twice a day for 10 days. Was previously prescribed Bactrim which resulted in only minimal improvement in clearing up the infection. Have been on the Macrobid approaching 3 days now with 7 more to go before finishing the 20 capsule prescription. At this point, other than experiencing some mild nausea and ocassional stomach cramps for about an hour or so after each dose, haven't had any severe side-effects or adverse reactions to this drug. M 57 3 days
8/26/2009
 1  chronic UTI i was prescribed macrobid by a urologist to take twic a day for 2 weeks then once a day for two weeks. by the third week I developed severe chills and fever 101 to 103 degrees with complete loss of appetite. I saw my primary physician on the 5th day with fever of 102.8. He did a complete lab, chest xray, and influenza test...all negative. My only other symptoms were shortness of breath and severe fatigue. I stopped the Macrobid and the fever subsided within 2 days. I am certain this was a reaction to this medication. F 57 3 weeks
8/23/2009
 1  Bladder Infection The morning after I took my last pill (2 per day for 7 days), I was achy, short of breath, slight fever w/cold hands & feet, slight nausea & headache. Tho I finally released 2-3 days of uncharacteristic constipation. BI appears gone, but talk about overkill! Don't know how long my symptoms will last, but I sure know what caused them. Typical of doctors! The treatment is worse than the disease! I am 5'1" 57 years old & EXTREMELY healthy, on no meds. I teach Weight Watchers. I always wonder if the same dosage would be given a woman 7" taller & 40 pounds heavier. Dtrs never seem to take this kind of thing into account. I TOLD him how healthy I'd been - it was a walk-in clinic, as I haven't needed a local dtr. Get my yearly physicals in Ojai. Shame on me tho for taking the scrip without googling it first. F 57 7 days
7/21/2009
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 1  uti Within one day, I thought I had the flu. By the fourth day, I had a high fever and could not eat anything. The fifth day I developed a rash on my entire body and had severe cramping and muscle pain all over my body. I went to the er, where they found that I had a heart rate of 180 and a fever of 105. I was admitted with a diagnoses of serum sickness. After two days in the hospital, I was released. The following day, I developed a severe blistering rash, and was diagnosed by my dermatologist with stevens johnson syndrome. It took me months to recover. This all happened 13 years ago, and I am amazed that this drug is still on the market. I was told at the time that my reaction was extreme and rare....I now see that this is not the case. F 57 6 days
8/9/2009
 1  UTI Instruction to take with food seemed to lessen abdominal cramping , but after finishing entire seven day dose, experienced rash of arms, chest area and entire face, muscle cramping of legs and arms, low grade fever, no appetite and lethargy. I was told this drug did not have sulfa, since I have an allergy to this drug, but now after reading these posts , I wonder that it may cause similar problems for those who do have an allergy to sulfa.I never take this drug again. F 57 7 days
6/30/2008
 1  uti Nausea, intestinal cramps, terrible gas, diarrhea, fatigue, headache pretty much non-stop. Feverish, chills, body aches especially in joints, insomnia despite fatigue. Yet another case of cure being worse than disease. Back to doc this am to find out what my other options are, as still have UTI after a week (and Christmas week at that) of feeling awful. Big thumbs down for macrobid!! F 57 7 days
2X day
12/27/2010
 1  uti severe abdominal pain, watery diarrhea, side pain, nausea, vomiting severe, face hot, body cold, achiness all over body, headache, heart rate 123, Blood pressure 198/99, short of breath please pay attention to these reviews. I have never been so sick in all my life. May end up in ER tonight. Do not ever take this crap. I have been wishing all night and all day to die it is so horrible. NO JOKE F 57
100mg 2X day
3/10/2010
 1  UTI Severe headache, UTI symptoms, extreme lethargy, chills and fever, sinus problem, depression Worst drug I have ever been on in my life. I kept thinking my UTI was recurring and they would prescribe extended use of the drug the finally retest me and see no infection - send me to my primary care doctor for the fever, chills, etc. - maybe a sinus infection ? - but found nothing and send me back to the urologist. By the way, both doctors and their staffs extremely annoyed by what I sensed they considered my 'psychological phantom illness' and usually given very cursory exams. Back and forth to my urologist & primary care doctors for three months - one entire summer. Neither doctor actually identified the drug as the problem until I did my own research and found this site. The urologist's nurse, in fact, scolded me when I told her the drug itself was causing me distress and told me it is an excellent drug and no one else had ever complained. I cannot even believe that this happened in this day and age and how ignorant these people are of side effects of drugs - not even to question a patient. I dragged myself to work for the entire summer, went to bed when I came home and spent my weekends sleeping. This was my first bad experience with the medical profession and I am now very afraid of getting sick and having to go to a doctor. F 57
1X day
6/20/2010
 1  UIT infection Hives, blisters, boils, rash, itching, Be careful with this one the symptoms may not show up for a week and boy they do show up really get your attention. F 57 7 days
30 2X day
6/9/2012
 1  UTI I finished taking the medication sunday morning. Sunday afternoon laid down to have a nap and when I woke up I had a really bad headache, chills and fever and nausea. That went away after 24 hours for the most part but tuesday morning I discovered a red swollen rash on my shins. Itchy and ugly. After reading so many bad reports I will never take this again. We need to be aware of what we are putting in our bodies. Sometimes the cure is worse then the ailment. F 57 6 days
100mg 2X day
2/28/2012
 1  To help not get another UTI. I took the 100mg for seven days a month ago,thinking I had a UTI but culture showed that I did not.I have IC and it was just a bad flare.The Dr. put me on 50mg to take at bed time,I noticed that I was nauseaed soon after taking it(took it with milk) and then when morning comes my joints hurt and then stomach cramps and diarrhea and lost of appetite,numbness in arms and hands.When I took the 100mg I noticed that I had to do breathing treatments and I just though my asthma was acting up.I didn't take it last night but still had the upset stomach this morning.From what I had read it takes a few days to get out of your system.I also have nodules in my lungs and now I am worried what my CT might show on them after taking this med.I go for my CT next week.I won't be taking this medicine again. F 57 3 days
50 mg 1X day
11/15/2011
 1  Slight bladder infection Prescribed after urine test showed "slight bladder infection" [no symptoms]. Extreme sore throat and lungs on first day. Breathing difficulty by third day due to increased lung and nasal congestion / sinus swelling. Painful nonproductive cough, raw throat, and hoarseness. Called physician re: insert instructions / warnings about "new infections" and potential fatality linked to lung infections. Physician Assistant's assistant advised symptoms unremarkable, probable cold, and not Microbid. By day four wracked with flu-like symptoms, headache, pain and tenderness inside mouth [gums & cheek], full-body aches, weakness, malaise, nausea, intensified lung, throat, nasal pain, congestion, impaired breathing, nonproductive cough making it difficult to sleep. Day 5 [yesterday] - no confidence disregard of Physician Assistant's assistant advise, stopped taking. No improvement by day 6. Not recommended for "slight bladder infection." Safety of this drug for patients with compromised immunity questioned. F 57 5 days
100 2X day
10/4/2012
 1   achy muscles, anxiety, thick mucus, waking up at night choking from thick mucus,night mares,tiredness, unsteadyness,flu like symptoms, would never recomend this medicine to anyone.......I have asthma......it made me worse!! breathing and thick mucus. F 57 14 days
100 mg 2X day
6/30/2014
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 1  UTI Severe chills, high fever, severe headache, sore ribs, shortness of breath and cough, joint pain. I have taken this medicine previously with no significant side effects (gas, mild diarrhea). This time symptoms occurred within 5 hrs of taking first dose and came on very suddenly. F 57 1 days
100 mg
6/29/2015
 1  long term suppression therapy UTI over 18 months I continued to get worse without any positive bacterial cultures in my urine-but had pain, fatigue, confusion. Finally I collapsed and ended up in emergency with diffuse intersticial lung disease and fulminant hepatic failure. My lungs responded to treatment, but my liver finally was necrotic. I received a liver transplant July 5 2008, spent 2and 1/2 months in the hospital, and will be on immunosuppressants forever. I also have neuorpathy in my right arm, though it seems to be improving. The effect of the drug is insidious-and the symptoms could I think have mimiced a UTI. I saw my GP at least twice a month, and a urologiest 5 times over the course of prescribed treatment. My advice is if you take this drug for more than a month, get frequent blood tests to check for liver function. Be alert to breathing difficulties. F 57 18 months
9/4/2009
 1  prevention of recurrent UTIs I was prescribed one 100mg capsule of the generic macrobid after intercourse. Because it's the season of viruses and flu, I didn't make any connection to the chills, body aches, lethargy, headache, cough, stratchy throat and sinus headache. After weeks of feeling awful, getting a little better and then feeling horrible again, i finally put it all together after reading this website. I am a very healthy 57 year old and to have an illness linger for weeks is not typical for me. I will never take this medicine again after reading all the other women who experienced similiar reactions. My doctor seemed surprised, but believed that it could be the drug. I can't wait until the drug is completely out of my system and i'm back to feeling healthy again. F 57 4 weeks
10/20/2009
 1  repeated UTI hives over 4 inches in diameter, fever, vomitting, wheezing, confusion and delirium Took a full week to recover after 20 hour hospitalization. Had taken it once before for a week and had small hive reaction and nausea, but misattributed that (apparently) to an allergic environmental allergy. NEVER TAKE THIS .... I nearly died and now carry an epipen just in case I get something similar again F 57 1 days
10/23/2009
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 1  Bladder infection High fever from 101-104, muscle cramps, lower rib cage on both sides of body felt like I had broken ribs, from the knees down broke out in hives and I was swollen, for a couple of days, I urinated brown, & headaches. I went to my family physician (before I broke out in hives, he had me me run a CT to make sure it wasn't my gallbladder or kidney stones causes causing the excruising pain! I had only been on Macrobid for 1 day when the symptoms started! the hives didn't break out until the 4th day, which was made me realize at that time it was a reaction! It has been noted in my chart at my family doctor and my pharmacy that I am highly allergic to this medication! F 57 10 days
2X day
6/12/2013
 1  UTI increasing fatigue, pneumonia-diffuse, and liver failure. Despite discontinuing the drug and under hospital care, my liver became necrotic from the drug; luckily I was in a transplant centre and received a transplant. Hospitalized for two months-awful experience. If you are on this drug for any length of time, even at the preventive dose, get regular liver function monitoring. F 57 90 days
100 mg 1X day
5/21/2014
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 1  used for a UTI I started having flu like symptoms after the first dose with lots of aches and pains. My knee joints seemed swollen and I was also dizzy. However, my UTI had been so extreme that I hated not to take it. My second dose caused even more symptoms that included extreme fatigue,confusion,itchy skin,tingling in my hands and arms, and it seemed that my vision was a little blurry! Needless to say I didn't take another dose! I reported it to my doctor and she said that I may have an allergy or sensitivity to Macrobid and she ordered another antibiotic. F 57 1 days
100mg
3/15/2017

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