DIFLUCAN Reviews (FLUCONAZOLE)

Average Rating: 2.3 (465 Ratings)

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 ANTIFUNGALS

 Type: Rx Drug

  

DIFLUCAN  (FLUCONAZOLE):  Fluconazole is used to treat vaginal yeast infections. It works by stopping the growth of common types of vaginal yeast (fungus). This medication belongs to a class of drugs called azole antifungals.   FDA Approval Date: 1990-01-29 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on DIFLUCAN: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DIFLUCANCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Vaginal Yeast Infection I took Diflucan years ago for a yeast infection - got rid of it quickly and efficiently with no side effects! Fast forward to this year. I had a major yeast infection, took Diflucan but this time had multiple weird side effects, including: peeling/swollen lips (with ulcers on the inside), nausea/vomiting, terrible stomach pains and diarrhea, heart palpitations, itchy throat and increased vaginal and anal irritation. I even developed hemorrhoids for the first time in my life, and I attribute it all to this drug. I think it severely irritated my mucous membranes and then this was only worsened by coupled chronic diarrhea I was having. Be really careful taking this drug..it's no joke. It's been 2 months since taking Diflucan and I am still having irritation down there. I think some of it is probably from the yeast infection itself but I just know that this drug definitely played a part in it. I just went to a vaginal specialist who said I now have contact dermatitis down there. I will never be taking this drug again. Had the allergy added to my med chart and everything. F 25 2 weeks
2X W
1/9/2021
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 3  Yeast uti Bad anxiety M 42 1 days
150 1X day
12/14/2020
 1  Yeast infection Have taken this before with great results. Don't know why this time it have me such horrible side effects. Chest pain, loss of appetite, nausea and tiredness. I'm on day 5 after last does and still not able to shake it off. F 46 3 days
150 1X day
12/14/2020
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 1  Vag Yeast Infection from Antibiotic Burning skin all over with no rash, pins & needles feeling, rashes in ALL moist areas (finger webs, armpits, butt crack, vagina, elbow creases, behind knee creases & groin creases. Chapped lips. AWFUL. Took 1 150mg dose then 1 150mg dose 4 days later for a yeast infection caused by antibiotics from getting a tooth pulled. I don't know if it was side effects from the Diflucan itself or if it was "yeast die off" my body was experiencing after taking it. Burning skin all over with no rash, pins & needles feeling, rashes in ALL moist areas (finger webs, armpits, butt crack, vagina, elbow creases, behind knee creases & groin creases. Lips got chapped and skin just very scratchy when anything touches it. Best way to describe the burning skin was feeling like I had a sunburn but no sunburn. I called my PCP and he didn't know what to tell me. Called a specialist and they didn't know what to tell me. I did a ton of research and found TONS of reviews of others who had similar symptoms after taking. Don't know if it was the "herx reaction" or side effects from Diflucan but would have been nice to have been warned of this beforehand either way. The skin issues triggered my anxiety because with no visible signs, I thought I was losing my mind. Woke up with horrible anxiety for about 4 days. Started noticing these side effects 6 days after the 2nd dose. I took the 2nd dose FOURTEEN DAYS AGO and my symptoms are just now SLOWLY SLOWLY SLOWLY getting better. They are just now manageable but still very much present! I have to keep F 36 1 days
150 2X O
12/6/2020
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 1  Vaginal thrush post antibiotics Tingling, itching, flushed face, canker sores Within an hour of taking my tablet my upper lip was tingling and started to swell and my face was flushed. I can now feel like sensitive blisters inside my upper lip. I also experienced intense firey itching down below that I have had to put ice water on. I was a bit worried taking the tablet as ended up with a mouthful of canker sores the last time I used Fluconazole but wasn't sure if it was just coincidence...now confirms it was these tablets so guessing these will erupt again in the next couple days :( I will look to use garlic or natural remedies next time as really don't want a repeat of this :( F 40 1 days
1 x 150mg 1X day
11/30/2020
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 1  Vaginal yeast infection Racing heart, rash on legs, with like blood spots under skin-appeared today, headache, anxiousness, upset tummy, diarhea, loss of appetite, sleeplessness. Overall. I feel like sh*t! Very scary actually. I avoid pharma drugs, and am sensitive to most. But, monistat over the counter did not work, so went to Dr. She gave me 14 day prescription! Read here 1 dose can work? She gave me 14 days! I am done today, and will never take again. For all of you out there, take a high 50 billion live pro-biotic to offset drug side effects. It works. I started vaginal estrogen tabs 3 mos ago & believe infection a result of that, as I have not been on birth control, or HRT for 20 years, & have never had an infection since. Gonna up my pro-biotic from once a day to 3x for next week, & go back to yogurt poultice! May take longer but at least I won't feel this awful. Beware, a drug to treat yeast should NOT have all these side effects. F 63 3 days
100 mg 1X day
11/26/2020
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 1  possible thrush/yeast infection Dry, swollen, burning, itching lips, nose, itchy face as well. Like i am reading from others, I have taken this in the past without any side effects. I had a mild version of this a few months ago when I took it and this time it has been quite extreme so that I will definitely not take this again. I wonder if something has changed in its production since so many people are having these reactions when they are supposed to be very rare side effects. F 42 1 days
1X day
11/24/2020
 1  Yeast infection Stomach pain, gas, bloating, diarrhea, tired. I switched to Monistat. The diflucan also made me feel blurry eyed. This is not for me. Seems odd that this drug does this to you. F 54 3 times
150 1X day
11/24/2020
 1  Yeast Infection I had taken Diflucan about 3 times prior without any side effect over the years. I was prescribed it again and about an hour after I took it my lips became very itchy and red, and even around my nostrils became itchy. I then felt like my blood was boiling in my veins. I was also taking an antibiotic at the same time so I thought it was just a rare fluke. 6 months later I needed to take Diflucan again and the exact same things happened but this time I wasn't taking any other medication so I knew it had to be the Diflucan because I've never experienced them any other time. I didn't want to chance it and take it another time in case the side effects become even worse so I let doctors know I have an allergy to it. They've all seemed a bit shocked that it could cause those side effects. I'm relieved to read other people here have had similar reactions and it wasn't just "all in my head". It works great for many people but some may have weird side effects that aren't listed even after they've taken this drug without problems in the past. It did work to alleviate the yeast infection quickly, but there's no way I am going to chance having the side effects increase by taking again, which is a big bummer. F 42 1 days
1 pill 1X day
11/6/2020
 1  Yeast infection Used to work like magic, now everytime I take it the next morning I have a swollen face that itches and burns! F 23 0 days
1X day
10/30/2020
 1  To prevent a yeast infection I've taken this many times before to prevent getting a yeast infection due to taking antibiotics. Three months ago I started antibiotics I took the diflucan and I woke up in the morning my lips were swollen around my lips on my skin was splotchy and red then turned to chapped skin and sore. . I went to the doctor and they gave me a steroid shot. I had no idea what had happened because I've taken this medication before with no problems so I figured it was maybe an allergy to the face masks I have to wear due to the Covid-19 pandemic. Fast forward to today and I took the medication again not realizing it was what had caused my issue before. I woke up in the morning same exact spots ,swollen lips twitch tingling and now very chapped on my skin in the same exact spots looks like rug burns for lack of better words. I can't take this ever again. F 51 1 days
100mg 1X AN
10/26/2020
 2  Yeast infection Swelling throat, pens and needles on skin, fatigue. Chapped lips, worn out, stomach issues F 47 3 days
50mg 1X day
10/25/2020
 5  Yeast infection I was given one dose of diflucan an the next day developed a sore throat, a cold sore in the corner of my mouth an a blister on the outside of my bottom lip and one inside on my gum that is so painfuL I havent been able to eat for the last 3 days. I feel so horrible right now I'm goin to ask my Dr for a cream next time cause this is rediculous F 46 1 times
1X O
10/15/2020
 1  Vaginal yeast I took this medication most of my life being a diabetic I'm extremely prone every time I take antibiotics. I have no idea if they changed something or what. I was working in a grocery store when I broke out in hives on my face and around my lips, at the time I was trapped behind the register and my lips itched not knowing they were hives i scratched the area around my lips with my teeth. The whole outside of my mouth was dark and covered in scabs, I had hives on my cheeks and forehead even a few on my arms. At the time I thought maybe this was a mix with the antibiotics, fast forward a year later I was in the hospital for super high blood sugar so the doctors prescribed this again while I was on stay, the same exact rash started within hours of taking it. I'm not sure if it's body chemistry or manufacture changed something but I really wouldn't recommend this to anybody. An anti fungal should not have such server symptoms you end up in the hospital for a one day dose. I'll never forget how long it took my face to heal being a diabetic with a poor immune system I looked beat up for real. F 22 1 days
1X day
10/8/2020
 1  thrush in my throat exhaustion, loss of appetite, stomach pain, dry mouth/nose, low blood pressure, anxious/anxiety I've taken both this and nystatin before for thrush and other than being anxious I was okay. This time around I first started taking nystatin and it gave me racing heartbeat and just feeling like crap so I called and they switched me to diflucan and now I feel worse. I'm tired and lightheaded(so I'm assuming my blood pressure is low), my nose and my mouth are so dry, I've lost my appetite, and I get short of breath when I'm doing too much(assuming because of the low blood pressure again). I hope I never have to take this ever again. I do have a doctor's appointment later today I'm wondering what she's going to say. How long do these side effects usually last??? F 36 3 days
10mg 1X AN
10/1/2020
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 4  Yeast infection Heart palpitations. On the 2nd day severe stomach cramps. They were so bad I was doubled over in pain. Headaches, dizziness, nausea, insomnia, bloating.... F 36 1 days
150mg 1X day
9/25/2020
 2  Tinea Versicolor Raw tongue; hard to swallow; itchy skin; red bumps, hives Not sure if it actually worked but the side effects wasn't worth it F 22 1 days
300 1X day
9/17/2020
 3  Sinus surgery recovery Had sinus surgery and was prescribed this medication to take for 14 days. I also had to take a z pack, which I finished. But today I had a real bout with some vertigo or dizziness. I have diarrhea, and nausea. At first I thought it was because of thezpack bc the side effects are similar to this medicine fluconazole. Then I realized that it could be this medicine bc I’ve never felt like thus when I took a zpack in the past. The episode was so bad, I really thought I might need to call an ambulance. Because the dizziness is so bad if I lay down, I’ve been sitting up all afternoon. I know the medicine is prescribed for fungus but I just can’t tolerate this medicine for a long period of time. I’m calling my dr tomorrow to let them know. I also too have had weird dreams while taking this medication. F 50 14 days
200 mg 1X day
8/26/2020
 3  Yeast infection Nausea and diarrhea bad stomach pain, I was given 2 pills , take one and a week later if I still had pain to take another , I'm on day 4 , I was feeling perfectly fine until two days ago bad diarrhea and stomach pain, and now today nausea , so I took something for the nausea cause it's bad like if I'm pregnant. I can say that today I do have a lot less pain in my vaginal area I feel like it's starting to work ! Hope I don't have to take the second pill I didn't think I would feel this sick and I just wanna feel better F 31 4 days
150 1X W
8/20/2020
 1  Yeast infection I've taken this drug on a 1-3 day dose before with no problems. The 2 week dose has sent me on a wild ride. Headache, nausea, rapid heart rate, trip to the ER for chest pain, diarrhea F 41 14 days
100mg 1X day
8/14/2020
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