There are 1202 ratings for the drug: ZOLOFT in the Askapatient database.

Key to ratings for zoloft: 5-Very Satisfied: this medicine cured me or helped me a great deal. 4-Satisfied: this medicine helped. 3-Somewhat Satisfied: this medicine helped somewhat. 2-Not Satisfied: this medicine did not work to my satisfaction. 1-Dissatisfied: I would not recommend taking this medicine.

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Rating	Reason	Side Effects	Comments	Sex	Age	Time Taken and Dosage		Date Added
				F  M
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4	COMING OUT OF A DEPRESSION	DRY MOUTH		F	432	24 days		6/25/2005
2	anxiety disorder	nausea,diarrhea,headache,muscle pain,tingling,pins and needle feelings,abdominal pain, gas,dry mouth,altered sense of taste		F	74	10 weeks		7/1/2009
5	Depression	Night sweats but not sure it's from the Zoloft. I also didn't like the weird feelings when I first started so I took half doses until I got used to them and then moved to the full dose.	I classify my life as "BZ" & "AZ" (before zoloft and after zoloft). I spent over sixty years depressed before. With zoloft I now know what "normal" life is like. But in addition to eliminating the depression it also eliminated the highs. (I used to consider myself a "mini manic depressive".) I take 100mg a day.	M	73	3 years		6/13/2006
4				M	72	180 days		9/14/2004
2	Depression	Horrible -- I don't think I will continue this trial. Constant nausea, some vomiting, constant blinding headache not relieved by any pain meds, jaw-clenching, tooth grinding -- all on the lowest possible dose.	Started with starter pack from Zoloft, skipped 4th day due to vomiting, decreased to 12.5 mg on 5th day, still with awful headaches and transient nausea on 8th day. I hear you have to get thru the side effects, but so far it has made my life worse and I am having a difficult time talking myself into continuing with this medication.	F	72	8 days		10/18/2006
5	anxiety, anger, depression	Chewing the tip of my tongue. Constant music in my head that is repetitive. I cannot make it go away unless I have music on so that it distracts me.	But still, I would not go off it. It has made my relationships with everyone better.	F	67	4 years		5/30/2005 Email
2	depression	dry mouth prickly tongue unable to sleep		F	67	4 months		5/2/2006
5	Depression, anxiety	It's been so long I can't remember.	I couldn't live without it. Have had to increase dosage to 150 mg/day. If I went to 200 mg/day I had more anxiety and restlessness.	F	65	12 years		5/10/2007
4	anxiety	anxiety agitation sleepy but now insomnia	youve got to do something about the cant sleep at night bit! its chronic!	F	65	5 days		4/14/2005
5	depression	none	Taking it for years	M	64	100 2X D		5/8/2010 Email
1	bi-polar disorder	Went into toxic situation when drug began to work opposite of intended usage.	Post-Polio nerve damage may have effected the horrendous situation I found myself in. Hospitalized during withdrawal when it caused a full-blown manic attack.	F	64	5 years		5/16/2005 Email
5	Anxiety and Depression	None that I can remember after ten years of taking it. The generic had a burning foul taste if it stayed in my mouth too long. Burt my throat for at least a half hour. Had no problem with the original Zoloft.	I had been taking Zoloft for ten years, very satisfied but the effectiveness as with any drug wore off. I have been put on Effexor in the past couple of days and I am not liking what I am reading about it. Hoping it will have the same effects that Zoloft had for me, NONE	F	63	10 years		10/5/2007 Email
4	extreme stress	It helped calm me during an extremely stressful time of assuming a caregiving role. I felt		F	63	1 years		6/20/2005
3	Depression	None	Seems to be doing the trick. I do feel better but very lethargic.	F	63	1 years		6/9/2006
5	Panic attacks after 13 surgeries	The first week was difficult; I wouldn't recommend driving at that time. I wasn't sure I was stopping the car and felt very unsafe. Some nausea the first week, too.	This drug absolutely saved my life. I began having what I called "daymares" after having 13 surgeries in a year and a half. These panic attacks were unbelievably frightening. I called my surgeon to ask for something for depression and she blew me off and told me to "deal with it"; I never went back to see her. I found another dr. who prescribed 100mg Zoloft. The shocking thing for me is that Zoloft relieved 90 % of my fibromyalgia pain !!! This is a HUGE thing for someone like me. I decided to go off of Zoloft about 5 years ago and BAM ! .... back came the pain. I worship this drug; I'm not sure I would have made it without it.	F	60	10 years		6/9/2008
5	Emotional Instability	I have taken a lot of ssri's over the last 35 years but this is the only one that works without any noticable side effects. It helps with ED also. I take generic, 50mg but buy 100mg tabs because the price is the same. I used to take brand zoloft until generic came out, I can tell no difference in the two.	Congrats to Pfizer Inc. You got it right this time.	M	60	3 years		7/18/2007
5	Depression following cancer	No side effects except constipation which is manageable with natural products. Worked quickly to lift my spirits and increase my optimism	I'm continuing a long term treatment for cancer which has a potential to increase depression which often follows a cancer diagnosis. I resisted taking anything for depression and anxiety but I couldn't stand being with myself. I feel better now, I'm calm and manage my break through anxiety well. It does not help me sleep but does help me be calm about not sleeping well. It is a good choice for me	F	60	2 months		4/6/2008
4	depression	I can't take the full dose without severe tension in my muscles. Therefore I take a lower dose with slightly less benefit to my depression.	Before taking Zoloft (started 2 years ago), I had taken 3 other antidepressants, each of which I had to stop because of either ineffectiveness or side effects.	F	60	2 years		3/26/2005
4	Obsessive Compulsive Disorder	I started on 200mg/day. Effective for OCD also eliminated anxiety. Had brain zaps and Restless Leg syndrome that affected the whole body causing a constant need to flex and move muscles. Had Muscle pain also, diagnosed as Fibromyalgia, I suspect that the muscle pain was a zoloft side effect. Decreased to 25mg for the past 5 years. Less effective for OCD, some obsessive thoughts break through but can be tolerated. Anxiety is back but mild enough to ignore. Side effects much better. Restless leg syndrome only occurs at night, and not every night. I can sit quietly and knit for long periods of time. No brain Zaps, muscle pain much less. 25mg gives me a tolerable balance of treatment and side effects.	It's been impossible for me to stop this drug. I can decrease it slowly but when I get down to half of a 25mg pill I can't seem to get lower. I've tried shaving off tiny bits of the pill over 2 week intervals but my body seems hyper sensitive to the decreases. I get a recurrence of OCD and anxiety, with the addition of anger, depression paranoia and irrational thinking that make me impossible to live with. The symptoms are worse than they ever were before I ever took Zoloft. Once I decided to simply stop it at the 12mg point and tough it out. I ended up in the hospital-- a psychotic episode. Worse than anything I ever had before Zoloft.	F	60	18 years 25 mg 1X D		6/18/2010
3				F	60			6/3/2009
3	suicidal ideation	I was on 5 mg and breaking that in half. once I went to one pill I be came MORE suicidal	didn't seem helpful	F	60	2 weeks		9/1/2009 Email
1	severe depression/anxiety	Constant nausea, alternating constipation/diarrhea, very anxious, sleepy but can't sleep, clenching jaw, waves of sadness, total loss of appetite, tremors when trying to write, moody and low. lethargic, no desire to do anything I used to love to do, feeling like I want to cry all the time	This drug works well for two of my kids, but they are taking it for anxiety only. They seemed to suffer very few side effects. I had taken Prozac for many years, but it wasn't seeeming to help anymore. I never had these kinds of side effects. Have since had trials on Cymbalta, Seroquel and Remeron. I didn't like any of them. I'm only taking 25 mgs of Zoloft in the morning, and it's only been for ten days, but I can't see doing this much longer. I'm already too thin, so weight loss and loss of appetite is not a good thing for me. Everyone says to give it more time, but I don't think this is the drug for me.	F	60	10 days		10/27/2008
5	DEPRESSION	sexual side effects		M	59	9 months		12/16/2006
5	fibromylia	some dizziness,	creates unreasonable sense of ephoria at times when you normally shouldn't be that happy	F	59	14 years		7/14/2008
5	brain injury (right-frontal)	Difficulty reaching orgasm (might also be a combination of other drugs plus age)		M	59	7 years		1/17/2005
4	depression	None worth mentioning.	This medication has turned my life around; I'd been suffering from moderate to severe depression for decades and was afraid to take antidepressents until my doctor convinced me to at least try Zoloft for a while. It's been about 4 years and I truly feel like a new person.	F	59			8/1/2008
4	seasonal depression, ptsd	jaw clenching, improved by taking dose at bedtime and reducing dose		F	59	2 months		11/20/2004
3	depression/dysthimia	Flattening of mood, dry mouth and weight gain.	It's the thrid anti depressant I've tried. I was allergic to Effexor and Prozac only worked for a short time. The Zoloft worked and did help my depression for a while, but after a year I don't feel like it's still helping. I tapered off once, but started to feel depressed again and went back on it. Now the dry mouth is really bothering me and I'm considering going off of it again.	F	59	13 months		10/13/2007
3	Anxiety and depression	Zoloft worked very well with the exception of a chronic stiff neck.	I had trouble sleeping when I began taking Zoloft, but after a week I was sleeping very well. I did have some mild agitation, but the worst problem was a stiff neck which became unbearable.	M	59	6 times		11/20/2002
2	depression, anxiety	increased anxiety, nausea, loss of appetite and weight,heartburn, diarrhea, eye twitching, jaw clenching, insomnia, have to take xanax in order to take Zoloft.	I have only been on this for five days, after coming off of Prozac. I'm not sure that I'm going to like this med. Will report if it gets any better.	F	59	5 days		4/25/2007
5	Depression	Only good side effects	Low dosage (25mg) daily. I literally felt it 'kick in' on the 8th night of taking it. Perhaps because it is a low dose, I don't notice any side effects, except that I'm not as depressed. I wouldn't want to increase the dosage because I think I wouldn't care about much of anything!LOL. After 2 years, I have starting having night terrors (yelling in my sleep) about once a week and after research on the net, I'm wondering if it is from the Zoloft.	F	58	2 years		1/7/2009
5	Anxiety, depression	Mild jaw clenching	I've tried various anti-depressants, some with disasterous results. Then started 150mg Wellbutrin and felt better but it stopped working so went to 300mg. This also stopped working. My doctor added 25mg of Zoloft for Anxiety it absolutely changed my life! I feel like "myself" again after 7 years of battling depression. For the first time in 7 years I woke up on a Saturday morning and felt excitement about all the things I wanted to do that day! Every day is a good day these days.===== I believe Anxiety was the root cause of much of my depression. I'm a happy, happy girl! No side effects at all except a bit of tinnitis and from the Wellbutrin (that improved over time) and mild jaw clenching. No weight gain. No sexual side effects. Zoloft works for me and one of my siblings but did not work for another family member who experienced a zombie effect.= Keep trying. I had lost hope but now I have my life back.	F	58	3 months 25mg 1X D		7/21/2010
5	migraines	loss of sexual desire for first 6 months, gradually came back...:-) occasional night sweats from neck up...	no more migraines	M	58	8 years		8/16/2004
4	anxiety, ADHD, etc.	None - it works just fine. I am very calm and relaxed and do not have the weight gain or sleepiness when I took paxil.		M	58	2 months		5/9/2004
3	POST TRAUMATIC STRESS DISORDER, DEP	BEEN ON THIS FOR OVER A DECADE. IT HELPED MY DEPRESSION AND INCREASED MY APPETITE. BUT NO APPETITE WAS ONE OF MY PTSD SYMPTOMS. BIGGEST NEGATIVE IS VIRTIGO, BRAIN ZAPS WHEN I TURN MY HEAD QUICKLY. ESPECIALLY WHEN I FIRST STARTED. NOW IF I MISS A DOSE I KNOW WITHIN HOURS BECAUSE THE VIRTIGO STARTS AS A WITHDRAWAL SYMPTOM. NO LIBIDO ALSO IS A PROBLEM	THIS DRUG HELPED ME, BUT I THINK THERE ARE BETTER DRUGS AVAILABLE WHICH DO NOT CAUSE VIRTIGO. HAVE HAD TO ADD WELLBUTRIN NOW FOR DEPRESSION, ZOLOFT NOT WORKING WELL ENOUGH ON ITS OWN BUT NOT ABLE TO STOP DUE TO VIRTIGO	F	58	12 years		8/26/2009
3	depression caused by pain	weight loss, weight gain, gas, loose stools,weird dreams, a feeling of not having many emotions. Sort of someone who has been desentisized.		F	58	1 years		12/21/2009
2	anxiety, depression seasonal affect	Increased anxiety, restlessness, and feeling out of control and panic. I told my doctor and they gave me seraquel (which is used for bipolar treatment. The thing is they just gave me samples without explanation. At this point I am ready to get all these poisons out of my body and just exercise. I am so tired of feeling bad, it's been 4 months now.		F	58			12/19/2007
1	depression	nausea, gases, diarrhea, eructation		F	58	25 days		2/24/2005
1	Depression	Of all of the antidepressants I've tried, this one had the worst side-effects. On the third day, I was climbing the walls (serotonin syndrome, it's called), praying to God to allow the effects to wear off more quickly. The only benefit I got from Zoloft was the relief of having it leave my system.		M	58	3 days		1/4/2006
5	mild depression, panic attacks, IBS	IBS immediately started calming down, panic attacks gone, after a few years bowels completely normal. depression lifted immediately. Migraines less severe. Slight weight loss :-) low libido :-(	this has been a wonderful help for my life. After some years of talk therapy, my shrink was convinced that my problems were largely biologically based. Reluctantly, I went on Zoloft - - it has enabled me to do well with work, balanced finances, more enjoyable and better quality relationships with friends, family, and husband. It's also helped minimize symptoms of menopause. Zoloft's persistent sleepiness symptom went away totally by increasing dosage from 75 to 100 mg.	F	57	7 years		3/4/2007
5	Life long depression	Sexually, I am unable to obtain an erection.	600mg daily of Zoloft is quite effective.Yes, I said 600mg daily. It has increasted the over all quality of my life. While, concerned about the side effects the beneiftes from the medications outweigh the side effects.I encourage any one on the medication to continue taking the medication.	M	57	12 years		10/15/2004
5	depression	none, except my cheeks were aching at first from smiling so much :-)	Wow, this took me from an anxious moody depressed person to a calm optimistic one in only a few days - I've been taking it for years, and don't ever want to stop!	F	57	5 years		8/15/2007
5	depression	loss of sexual desire and anorgasmia; difficulty maintaining a quality diet; difficulty getting up in the morning	My experience is that there is a minimal dose required to be effective, and that there is a maximum dose above which the effectiveness wears off. At the proper dose, the effect is darned near magic. Whoever said that the generic is not as good as the real Zoloft is exactly right. There is a profound difference, and it's not made up by increasing the dose. The drug acts very quickly, and the loss of sexual desire is almost immediate. I haven't gained weight yet, but I can see how it would be possible. I have a yearning for donuts and recommend an aggressive program. Also, the combination with alcohol is seductive...watch out.	M	57	3 months		6/28/2007
5	restless leg /insomnia/anxiety	A little nausea, off and on for the first week only.	It is the best medication that has ever happened to me. I go to bed, get a good nights sleep, no restless leg sydrome since the 4th day of taking Zoloft. I love each day.	F	57	1 years		2/26/2009
4	panic attacks	I'm filling this out for my husband. The only side effect he is having is tics--rubbing his forehead constantly. Really having difficulty stopping. Worth it, though, considering that he's back to normal.	It has completely helped his edginess and feelings of panic.	M	57	2 months		9/30/2007 Email
1	anxiety	insomnia, severe muscle aches, increased anxiety, eye pain, constipation	My mood greatly improved quickly. I have experienced illness within my family which caused a great deal of anxiety. Have always suffered from anxiety and panic. These symptoms improved very quickly. All crying stopped. Panic controlled. I hated to go off the medication, but my doctor took me off due to bad side effects. I hope to find something else to help me.	F	57	2 weeks		9/4/2005
1	Depression / Anxiety / PTSD	Made me have tremors, also made me feel like I wanted to crawl out of my skin. I have been off this drug for almost 3 years and I still feel like this! This is the worst drug on the market!		F	57	2 years 200MG 1X D		7/25/2010
4	anxiety			F	56	3 days		3/10/2007
4	depression	Absolutely no libido!		F	56	8 years		11/17/2002
4	depression	slight headache		F	56	13 years		1/25/2009
3	Depression	Sleepy, buzzed, spun out, however I was like that before I started medication, then became more accepting of abuse. Not good.	In hindsight, should have kicked out manipulative verbally abusive husband, taken half of his pension, and started a new life, then I would not have needed to take any medication at all!!!! Now he's just an old ugly fart and has made a decision for his family. Was it worth the fight? I'm not sure.	F	56	12 months		11/9/2008
3	anxiety	Fuzzy thinking, memory loss		F	56	1 years		5/8/2005
3	depression	Tolerence.		F	56	4 years		12/19/2004
3	depression	loss of sex drive	Of all the antidepressants I've tried Zoloft is the one I would recommend. Be careful if you go off this drug, if you restart it it may not get you back to where you were before. I learned this the hard way. Somehow the brain chemistry changes.	M	56	10 years		3/10/2007
1	anxiety	big time dry mouth, tremblies, insomnia, after 4 days a total activation of intense and unbearable anxiety	Had to quit after 14 days. Feeling much better. Lesson: If one is treating anxiety reasonably well already, then watch out for quickly jumping to an ssri.	M	56	14 days		6/3/2005
5	depression and anxiety.	None		F	55	4 years		5/10/2004 Email
5	Depression/ Anxiety	Constipation, low sex drive, weight gain	Zoloft has really improved my quality of life. I'm happy & the anxiety is gone. The benifits outweigh the side effects for me. I try to eat well & exercise to fight the weight gain, also increase water intake. I take Zoloft in the morning & Trazadone at night to balence the increased energy from the Zoloft. I sleep GREAT.	F	55	10 years		8/29/2009
4	depression	Difficulty in reaching orgasm.	Dizzy spells when coming off of Zoloft if done cold turkey.	M	55	5 years		12/15/2000
4				M	55	2 years		2/4/2002
4	panic/depression	yawning ,no big deal, tired all the time legarthy sweating, but overall 90% cure of panic attacks,thank goodness. seems to have lowered my anxiety .	at least has me back where i can function . would appreciate any comments. also on xanax and therapy every 2 weeks	M	55	2 years		2/4/2002 Email
4	depression related to health issues	difficulty reacing orgasm, weight gain	i've been taking zoloft for over 15 years and yes it works although the generic does not seem to work as well. as long as i do not exceed 100 mg, the above side effects are minimal. i've tried many other antidepressants over the years but had too many side effects and always came back to zoloft.	F	55	15 years		4/12/2008
4	Depression/Panic Attacks/IBS	Strong feelings of being spaced out several times a day, uncontrollable muscular twitches (tics) throughout my body when I lay down, 'brain fog', lousy short term memory, dizziness	I was prescribed Zoloft 50mg and have also taken alternatives Xydep, Xypex and generic brand GenRX. They all work fantastically for depression/negative feelings - I've gone from deep depression, 'black moods', panic & anxiety attacks and suicidal feelings to feeling positive & happy; also more patient and tolerant with others. SSRI's don't work at all for my IBS. Initially I had no side effects - I felt great - but after 4 months,I started to experience the abovementioned side effects - the muscular twitches particularly concern me, and after losing my balance and falling twice within 10 mins one evening, I am slowly reducing the dose and hope to quit entirely soon.	F	55	5.5 months		5/10/2008
4	chronic panic attacks	delayed ejaculation to the point of occasional embarrassment, some loss of libido,slow but very steady weight gain. (30 lbs)	Works great for anxiety and panic attacks prolonged erections are a plus	M	55	2 years		8/10/2008
3	major depression; ocd	breathlessness, twitch, sleeplessness, increased appetite	I am ramping up right now due to increased suicidal ideation. I don't like the way I feel physically but the intrusive thoughts have eased and the depresion seems to be lifting. Hope I can stay the course; it may be interacting with my blood pressure med--metoprolol.	F	55	6 months		2/12/2009
2	depression	weight gain, hairloss, hallucinations, back pain, muscle spasms, numbness in hands	The drug has made a difference in my life. I have people who work for me that have seen a change and don't know I am taking an anti-depressant. I only take 50mg and life is a lot nicer. I am more tolerating and less judgemental. But the side effects I am experiencing are bothersome. I was suprised to read through the comments and no one elses experienced hairloss.	F	55	30 days		2/29/2004 Email
1	depression	Buzzsaw high followed by near-paralytic low	My doc gave me samples. I took ONE tab one morning, turned into a whirlwind at work...at 11 at night I was still going strong, packing my briefcase to take work home to finish until someone on the night shift stopped me. I'd already worked 14 hours! Then the next morning, I was so totally exhausted, I literally could not lift my arm off the bed to dial work and tell them I couldn't get there. The experience ranks among the worst in my life. Took about 48 hours to feel like something other than a total zombie.	F	55	1 days		5/5/2004
1	OCD Doze was high...250 mg.	involutary back spasms when falling asleep; feeling of sexual stimulation in genital area ... very distracting; social withdrawl; thinking I'm going crazy Back spasms may be permanent...now on 150 mg and still have them every night		F	55	3 months		1/23/2005
5	PMDD...Menopausal symptoms	Initially, I experienced a dry mouth, diarrhea, headaches,and dizziness.	I have been taking Zoloft for 10 years now and it really helped my severe PMS/Menopausal symptoms...However, I don't think the generic is working as well. Everytime I go and get a new batch, I experience what feels like withdrawal symptoms (body ache, down feeling, etc.) After a few weeks on the new batch my body seems to adjust, but I don't think I can continue going thru this, so may ask my doc. to switch me back to the brand name...Has anybody else experienced this??? I would appreciate feedback...THANKS!!!	F	54	10 days		5/9/2009 Email
4	Anxiety	Weight gain, teeth grinding (cracked teeth) low sex drive	Zoloft did reduce anxiety however (50mg) cannot stand weight gain and loss of sex drive. How do I wean myself of it??	F	54	6 months		2/28/2006
4	relieve hot flashes	some dry mouth, headaches	it actually worked. Didn't get rid of them, but makes them a lot less. It also improved my mood, although I didn't take it for that.	F	54	2 years		3/13/2007
3	Depression	Lack of orgasm, yawning, tiredness, jaw-clenching.	Started on 50mg, then 100 after 2 months. Initially felt like I had the flu for a week, then kicked in and felt much better for a couple of weeks. Still less depressed, but feeling a bit dopey, and side-effects getting me down.	M	54	3 months		2/20/2006
2	depression	Anger, a desire to do something bad to someone, lash out at other people.	This drug made me feel angry like I wanted to hurt someone. I had been going to the local Mental Health Center, they prescribed it, when I started feeling angry I went back to tell them I didn't like the way I was feeling, but they didn't want to hear that. They wanted me to keep taking it, said if I was level, that was what mattered. At the end, they put me with an old doctor who looked 80, all he wanted to talk about was a list of herbal medicines I'd given them at the start as some I'd used. When I tried to talk about the anger, he brushed me off, went back to the glucosamine/chondroitin, Echinacea, St John's Wart, said I should never take anything an MD had not prescribed. I tried to tell him I wasn't taking any of them right then, & that they were sold thru drugstores, he wouldn't listen. I gave up in disgust. I went off Zoloft myself & started feeling better within a week. The anger went away.	F	54	5 months DK 1X D		6/2/2010 Email
2	Clinical Depression	Extreme neuropathic pain	I have been on quite a few antidepressants, and the doc and I decided to try Zoloft. Started with 50mg, then 100mg, then 150mg intending to work up to 200mg. By 150mg, I was in excruciating pain from my feet, burning and stinging and traveling up my legs. My back muscles also hurt, but the feet were by far the most unbearable. I am diabetic, with good blood sugar control, so this intense pain made no sense. I went back to Lexapro, and doc appointment is today - I think we are going to try Cymbalta.	F	54	3 months		5/4/2009
2	Severe Restless Leg/Insomnia	Weight gain, it set off my irritable bowel with pain, cramping and high mucus content. Upper GI bloat and feeling like my guts were irritated. I felt floaty and confused, no concentration. Poor sleep. Over emotional.	It seemed to work for the first two weeks then my dancing legs came back, and I started to get over emotional, shaky, depressed, confused, crying, agitation and not helping with sleep. I will stop using it.	F	54	2 months		4/18/2009
5	depression anxiety	Very sick first day, thought I was going to pass out and was on only 25mgAfter that felt great for 3 months	Have raised dosage to 100 mg and feel like myself, No side effects, Regained my appetite. Thank god for this drug	M	53	150 days		11/18/2008 Email
5	panic disorder	weight gain	Had debilitating panic attacks for more than 25 years before starting zoloft (100 mg.). I have now been panic free for years thanks to this miracle drug.	F	53	13 years		1/26/2005
5	Depression	Some ringing in the ears, diarreha (not terrible), harder to achieve orgasm, few headaches the first week. Some insomnia, and sleepy more during the day.	Had been on Serzone in the past - this is better for the depression, but not for the sex thing - fair trade-off however. Had also tried Paxil, Celexa, Prozac, & Topomax in the past - hated all of them. Got immediate relief from this candy - the brain fuzziness lifted immediately - I mean the second day I was on it. Maybe the other symptons will subside over time - we'll see. On 50mg a day - not severe depression, but felt myself sliding into it. I had been off SSRI's for about two years, and have been feeling like I'm wearing a mask.	M	53	21 days		5/3/2005
5	anxiety	Somewhat unmotivated-- love the medicine but have gained serious weight!		F	53	2 years 150 1X D		3/3/2010
4	depression	diarrhea at first. sexually I get an erection but ejaculation is delayed and sexual pleasure is low		M	53	9 years		9/1/2004
4	depression			M	53	18 months		2/20/2005
4	Depression	Weight gain (15 lbs)in six years, fatigue, no interest in sex; decreases initiative (ho hum, who cares? syndrome)! Note: weight gain might be menopause and may have occurred anyway.	Stops hot flashes due to menopause.	F	53	6 years		10/26/2002
3	depression/anxiety	none		F	53	7 months		8/2/2005
3	depression, panic, anxiety	tinnitus, annoying ear ringing, increase in headaches	was hard for first 3 weeks--insomnia, intense depression It did help the emotional aspect after that but the ear ringing is very distracting and hopefully not permanent. My doctor urged me to stay the course so I am still taking it but he doesn't know about the ear ringing yet. I have noticed small increase in wax in the ears. I scheduled an appointment to see him in 10 days due to my work schedule and just hope this ear ringing is not permanent damage. It has helped my attitude with some very complex problems I am dealing with. I am afraid of withdrawing this med without talking to my MD	F	53	7 weeks		1/31/2006 Email
2	Anxiety	Sleepy, night sweats, nervousness, loss of appetite, no sex drive	I feel a little calmer, but not enough for me to continue taking this drug. Can't sit still, constantly shaking my leg, absolutely no desire for sex. Enjoyed the weight loss. Think I'll just try to cope with life without any medication.	F	53	3 months		7/11/2002
1	"depression"	Weight gain, hypomania, serotonin syndrome, total and permanent sexual dysfunction	Evil, pure poison....run for your life	M	53	4 years		4/29/2009
4	depression	gained 5lbs, decreased sexual desire	I was on 50mg for 8 years, after a while it wasn't helping so the doc increased it and I am much happier now. Really very few side effects--I think it's great.	F	52	10 years 100 mg 1X D		7/31/2010
3	anxiety	jitteryness, tickle in throat. no ability to have sex		M	52	7 months 25 1X D		8/18/2010
3	bi polar	Loss of sex drive,electrical like brain zaps going off in my head feeling like Frankenstein, diarrhea and the worst effect of all, grinding my two front teeth down to nubbins at night in my sleep in the course of being on it for ten years.	Had to get constructive surgery on my two front teeth that got ground down to nubbins due to this drug and grinding my teeth in my sleep at night. Got off this drug recently and glad I did. Still haven't gotten my sex drive back after three months of being off of it.	F	52	10 years		11/18/2007 Email
2	depression/anxiety	A few days of sick feeling when starting, and when increasing dose	Got up to a fairly high dosage (think it was 200 mg) and felt nothing. No good, no bad, no energy, no lack of energy... just nothing. Some people love it. Actually, I haven't found an SSRI yet that works for me.	M	52	3 months		4/12/2008 Email
2	Depression	nausea if I took on an empty stomach, diarrhea after dosage increase which subsided after a month	Started off on 50 mg Zoloft daily and gradually increased to 150 mg. Had about 1-2 weeks of feeling great on the 150 mg dosage (especially after the diarrhea subsided), and then suddenly symptoms returned. Added buproprion 100 mg twice daily and symptoms greatly improved after 4 weeks (which is where I'm at now).	F	52	5 months		10/28/2009
1	Mild Depression	Severe teeth clenching/TMJ which caused excruciating headaches -- clenching came on right after taking the dose and would gradually wear off -- took me three days to figure out the connection, during which I was laying in a darkened room with a migraine.	Do NOT take this drug if you have a history of migraines or TMJ -- this was the worst three days of my life till I figured out the connection from Googleing it -- the manufacturer doesn't say anything about this but there are thousands of hits on the topic.	F	52	3 days		2/23/2008 Email
1	Adjustment Disorder	None	No effects--postive or negative. Quit cold turkey with no problems.	F	52	5 weeks		10/12/2007
5	Severe PMS	When on 50 mg, had jaw clenching--very weird. Lowered to 25 mg, no symptoms. Helps with the PMS, also helped with IBS and overall outlook.		F	51	11 years		10/6/2008
5	severe chronic depression	apathy, occasional dizziness when dose is not 'on time'	terrific for overcoming 'black hole' depression; worked when others failed..allows a much better outlook on life	F	51	9 years		11/11/2006
5	anxiety	Good response almost immediately - I felt less anxious from the first few doses. I was very sensitive to the medication, and had drowsiness, stomach upset and tiredness. Some of these were unpleasant - I felt almost like I was getting the flu - sort of out of it. Cutting back on the dose resulted in immediate improvement. I learned to increase the medication very very slowly. increased by 12.5 mg every 3 to 4 weeks. Took nearly 6 months to get from 25 mg to 100 mg daily, and another 4 to 6 to get up to 150. I occasionally take 175 if I feel that I need it.	Zoloft works for me, but also in combination with psychotherapy. I don't think the meds were enough for me. The biggest difference that I perceive is that I now experience a whole range of feelings rather than irritation, anger and anxiety.	F	51	3.5 years		9/4/2006
5	Depression (borderline bi-polar)	The only significant side effect I have had with Zoloft is weight gain--I have been taking the drug for about 8 years, and have gained about 30 pounds over my normal weight. I never had a weight problem before this. When I first began taking the drug, I did have a few other side effects, but they only lasted a few weeks. Dry mouth and constant thirst were the negative ones (that only lasted 3-4 weeks, then went away), and, oddly enough, weight loss was the positive one (I lost about ten pounds, but obviously it all came back, and more.)	IMPORTANT---I was prescribed Zoloft by a psychiatrist after a thorough psychological exam. I go in for a re-check every three months. Having a psych professional regularly monitoring my mental health care has been the reason, I believe, for my success with Zoloft. If you are having problems with Zoloft, and have not consulted with a psychiatrist, you may want talk with one about your treatment. For me, Zoloft has been a life-saver.	F	51	8 years		5/2/2009
5	anxiety, couldn't sleep	I find myself rubbing my feet in bed (never did this before) and tend to want to shake my legs. Lost weight at first.	This medication has helped me reduce my level of anxiety. I sleep better at night (most nights). I used to wake up in the middle of the night and think about all the things I should have done and what I need to do, etc. The Zoloft has helped me a lot.	F	51	3 months		3/24/2009
4	panic attacks, nervousness	loss of desire in sex weight gain		F	51	3 years		9/16/2002 Email
4	Depression Premenopausal	Slight headache the first few days starting medication. Some diarrhea the first week. Started on 25 mg daily and moved up to 50mg. Lack of appetite which is a good thing for me.	It has helped me tremendously. I had panic attacks for years and never told anyone. They are completely gone. I do not cry as much and do not have sad feelings or obsess as much as I was doing. I do not seem to over react as easily. I was against taking this medication and have never taken an antidepressant before. I have to say it has worked well. I have no sexual dysfunction on it at all. I would say it has eased my premenopausal symptoms also. Difficult time in life, parents dying, kids leaving, losing my beauty and aging. It has made it easier. I stay on 50 mg daily. 100 mg seems to make me grit my teeth and make me a little tense. 50mg works well for me. Also I felt the effects right away, it did not take weeks for it to kick in. Hope this helps others. I have had no yawning. No weight gain.	F	51	2 years		2/5/2005
4	panic attacks	none		F	51			3/31/2005

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Average rating for drug: 3.4. This page is printer-friendly; use landscape print with background color turned on.

Key to ratings: 5-Very Satisfied: this medicine cured me or helped me a great deal. 4-Satisfied: this medicine helped. 3-Somewhat Satisfied: this medicine helped somewhat. 2-Not Satisfied: this medicine did not work to my satisfaction. 1-Dissatisfied: I would not recommend taking this medicine.

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