DURAGESIC-100 Reviews (FENTANYL)

Average Rating: 3.9 (148 Ratings)

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 ANALGESICS, GENERAL    DEA Schedule II   

 Type: Rx Drug

  

DURAGESIC-100  (FENTANYL):  See also Warning section. This medication is used to help relieve sudden (breakthrough) cancer pain in people who are regularly taking moderate to large amounts of opioid pain medication. Fentanyl belongs to a class of drugs known as opioid (narcotic) analgesics. It works in the brain to change how your body feels and responds to pain. This medication should not be used to relieve mild or short-term pain (such as due to headache/migraine, dental procedures, surgery).   FDA Approval Date: 1990-08-07 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on DURAGESIC-100: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DURAGESIC-100COMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  Ruptured/disc/tumors/spinal/column Constipation; but preventable by taking stool softner with mild laxative I have had the pain since '95 and worked until I couldn't anymore (had other issues too) I went thru the mill taking narcotics that made me a walking zombie and it was great to get releif w/o the side effects of being a zombie; at first I didn't need anything else; but after time I had to add 10mg percocet 1-2 every 6 hours; but the script was for only 60 a month. I'm in extreme pain now; the right side of my neck; right shoulder cape; and right arm; I have to hold my right arm in place across my chest; this has been going on for over 2 months; I'm to see doctor tomorrow about increase of percocet or adding something else or changing to something else. I've been sitting in my recliner with my cordless mouse and keyboard looking for what to suggest. If anyone knows what to suggest I would appreciate a email [email protected] Thanks M 2001 years
12/13/2004
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 5  Reflex Sympathic Dystrophy At this point I really don't have any side effects. the exact dose is 275 every 72hrs. The fentanyl patch saved my quality of life, such as it is. I was in excrutiating pain for 2 years while trying all those oxy,,,whatever pills on the market until the patches were introduced to me and finally some relief. The only problem I problem I have with them, honestly, is that over the years I have been titrated up on the dose so much, because the disease I have is a progressive one, that there really is not much further to go without stopping my breathing. And when I need surgery to change the battery in my neuro stimulator, what pain medicine do they give me?? Fentyal is the top of the line. I've been given dillaudid before and it takes the edge off. But that's the problem with this medicine...its fantastic for major and long term pain, but be careful.....there is a limit....I know I've reached mine and now I'm in a predicament and I still have more and more pain, as well as break thru pain. F 47 18 years
275 3X W
2/8/2016
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 5  Chromnic pain after multiple spine The only side effect I have had is mild constipation which resolved itself once I added more fiber at breakfast. The Duragesic Patches are truly worth their weight in gold IF the Doctor who puts you on it increases the dose until the pain is mostly resolved. I do on occasion take break-through pain medication,Dilaudid, which is inexpensive. The lower the doseage you can deal with on the patches the better off you are as the longer you are on them you do build up to a tolerance to the drug. I have been on Duragesic Patches for nine years and am still only at 150ugh. Three hundred is the maximun dose but you definitely want to save those higher doses for critical life threatening complications down the road, ie. cancer. Duragesic Patches did not work for pain control after surgery for me and methdone had to be used, then down-graded to morphine and finally the Fentinal after the severe pain had resolved. If you are not getting good coverage in the hospital after surgery because the nurses cut back on your meds without the Doctors approval when you still need heavy pain control call in the pain doctors who work at the hospital, some nurses are relentless at not caring about your comfort level. It's dufficult being a chronic pain patient physically. Keep your resolve strong, your mind focused, and strive for a better life in the future. F 62 9 years
10/22/2004
 5  Severe Spinal Pain/Fibromyalgia See note below The only comments I wanted to add regarding the Durgesic Patches are: 1. Duragesic Patches have given me the power to lead a somewhat normal life when my last three spine surgeries failed to give me any permanent relief and the pain became intolerable. 2. The ONLY MAJOR downside to the Duragesic Patches is the cost which is prohibitive when one does not have insurance coverage. This is tragic because some people who desperately need the Patches are totally out of luck. It is a drug that you can not just stop taking you must be weaned off of it and withdrawal is doable but very difficult. We chronic pain patients need to have to have some plan we can fall back on if we have lost jobs or insurance. No human deserves to suffer horribly just because they don't have the money to pay for this drug. PLEASE NOTE: If you are over 55 you can get a discount at K-Mart on the Patches which makes a huge difference. Remember it is not just the drug company which causess the price of the patches to be so high/ F 62 9 years
10/22/2004
 5  Generalized internal chronic RSD Nausea, vomiting, tiredness I tried over 60 various medications to control the intense chronic pain caused by my generalized internal chronic RSD (Reflex Sympathetic Dystrophy). Only strong extended release narcotic painkillers work for me. The one that works best for me is Duragesic (brand name fentanyl patches made by Janssen Pharmaceutica). Generic fentanyl patches do not work as well for me, if at all, and cause me much worse side effects. I can say without the shadow of a doubt that Duragesic patches gave me back my life, that is, they gave me a life worth being called a life. Thanks to the Duragesic patches, I can now work. I can also do the activities I enjoy most: sky diving, horseback riding (especially circus type), water skiing, rock climbing, mountain hiking, etc. I can never thank Janssen Pharmaceutica enough for making these wonderful fentanyl patches. The only negative point is the very high cost of the patches, for patients whose medical insurance will not cover fentanyl patches and for uninsured patients. F 37 9 years
125 mcg 1X O
11/25/2011
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 5  Rectal neuropathy, crohn's disease drowsiness, dizziness, lightheadedness when doing lifting or any work. great pain relaiver with out the narcotic drowsiness feeling of peaks and half life's and lows of taking pills for analgesic pain relife. Duragesic is pure pain killer 24-7 and for the 8 years i have added years to my life from /apap/tylenol toxicity that i was geting with other pain killers not to mention its 80X stronger than morphine what a medicine. M 27 8 years
5/26/2007
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 5  Rectal neuropathy, crohn's disease drowsiness, dizziness, lightheadedness when doing lifting or any work. great pain relaiver with out the narcotic drowsiness feeling of peaks and half life's and lows of taking pills for analgesic pain relife. Duragesic is pure pain killer 24-7 and for the 8 years i have added years to my life from /apap/tylenol toxicity that i was geting with other pain killers not to mention its 80X stronger than morphine what a medicine. M 27 8 years
5/26/2007
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 5  HepC related Perip. Neuropathy none! I don't even have withdrawal syndrome anymore I am on 4 100mcg patches every three days. I used to take MEGA doses of morphine (6000mgs +). I had edema in my legs, I lost my cough reflex and got double pneumonia, I collapsed one day and almost didn't wake up due to CNS collapse. I suffered supremely coming off all that morphine, but I would do it again in a heart beat. I am aware of my surroundings again, I can remember going to the movies with my wife, I can do little things around the house. I have my life back! thanks to Patches and suckers. M 56 8 years
8/17/2008
 4  Lupus pain, Fibromyalgia Reduced appetite, sweating, mild nausea I use the generic, mylan brand fentanyl patch. I prefer this to the duragesic patch which gave me some skin irritation. Mylan sticks better and does not irritate my skin. I am so glad for this long lasting patch that gives me continuous relief for several days. I prefer it to popping oxicodone every few hours. Other pain meds caused way more ups and downs and fatigue than the patch. I feel almost normal, pain is not gone, but much reduced. Without this, its was excruciating. I can lead an active life as opposed to being bedridden with pain. Just wish it wasn't so expensive. Fortunately my insurance has been covering the cost. I would give it 5 stars if sweating wasn't an issue and if it didn't cost so much, and if it was easier to get off of. Once you start this drug, it is extremely hard to get off of because the withdrawals are so severe. So I try to stay on the lowest dose I can tolerate. F 53 8 years
175mcg 1X O
9/7/2011
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 3  degenerative discs failed fusions No appetite whatsoever Severe weight loss Dry mouth Difficulty passing urine Palpation difficulties falling and staying asleep Lack of energy I started on 25mcg patches 8 years ago but after a while your body gets used to it, so it doesn't have the same pain killing effect which necessitates you going onto a bigger dose. I'm now on the largest patch and have been for nearly 4 years and I still find the pain to much to bare even with taking oral morphine on top for breakthrough pain. M 8 years
100mcg
10/1/2015
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 5  Fibro, herniated discs, neuralgias mild constipation, skin irritation with Duragesic brand when worn above waist This medicine literally saved my life. Before it I was in such severe, constant pain that I was actually seriously considering suicide. I had zero quality of life. This medication allowed me to be functional again and although I am far from being pain-free, my quality of life is pretty good. I am on disability but am able to have a life now. I would highly recommend this medication to anyone with long-term, severe chronic pain not getting relief from other pain meds. I change my patch every 48 hours because on the third day it seemed like the drug was wearing off and I was needing lots of breakthrough pain meds. (Many Medicare Part D plans pay for up to 15 or 16 patches a month so ask your insurance carrier if you have the same issue). I am now on minimal breakthrough pain meds. I have been at the same dose for 6 1/2 years and have been able to avoid increasing the dosage by using alternative therapies along with the patch. I have found that the Mylan brand, being a smaller patch, causes less skin irritation than Duragesic, especially when worn on the very lower back/top of buttock area where less pulling occurs with movement. Although the manufacturer tells you that you should wear it above the waist, this is only because they only studied it there, but I had no decrease in effectiveness wearing it on my lower back or upper buttock area. The patches also stay on much better for me there, with no need for tape or overlays. F 34 7 years
75 mcg 1X O
2/26/2010
 5  Osteo Athritis, Fibromyglia mild constipation, occasional mild sedation and or mild insomnia when patch is on for the 1st day. As a chronic pain sufferer I am grateful to have awesome pain relief that has given me my life back. You name the drug, clinic,specialists-been there-tried that!! Do not abruptly stop this med- follow all directions and keep your MD well informed. F 37 7 years
9/21/2005
 5  DDD Spine collapsing 3X Surg/fusion First month diff slow breathing, but give it time. You get use to it and no longer notice these issues. Mild sleeplessness. Euphoric when tired. Black-outs when sleep deprived. Standing-sitting-driving. Its like sleep walking. Only if I have no had even near adequate sleep. WOW! What a life changing drug. Tried every other narcotic on the market for years ending with oxycontin 80mg. I was gagging taking so many pills. Though the patches must be used at 2 day intervals. 3 is just an uphill battle fighting to get it back under control. Most will need Tegaderm or overlay from Jannsen. Takes a month or two to get used to but when you get at the right dose you can live virtually pain free. Don't come off it and don't run out by abusing them. Major withdrawl, near seizure-like on high doses. I am on 400mcg every 48hrs and have not seen anyone here even close. Read that the highest you can go was 300. Wrong! Had Dr tell me he had people on 600. I could easily go that high now after 7 years. I was in a wheelchair and could not stand straight upright. I have my life back. Driving, housework, standing on concrete floors. You name it. I can go 90% of the day pain free with Actiq as a breakthru. Had some issues with surgery anesthesia. I seem to F 40 7 years
2/28/2008
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 4  Failed back surgeries I also am suffering from severe nerve pain and have been given methadone for that. Duragesic is the only medication that works for me and I like it due in part to a past addiction to codeine. With a patch and the fear of ODing on Duragesic it is the best method for me. I change patches every 48hrs and I have now been on the 75mgc for so long on the second day I am feeling withdrawal symptoms of constant tiredness. M 59 7 years
75mg 1X day
8/7/2011
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 3  Fibromyalgia.and back Now after7 years on fentanyl ive noticed it makes me hurt more.anyone else having this problem.it was a miracle.at first. At first it helped me 100%.not anylonger.it makes me now hurt worse. F 58 7 years
100 mcg
6/23/2017
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 5  Complex Regional Pain Syndrome dry mouth, occasional withdrawal symptoms, fatigue, constipation, initial skin rashes on application site Has the potential to move you from constant intense pain and hopelessness to managed pain levels that are livable. I don't know if it is possible to get to a zero level of pain with it, perhaps because I am resistant to take more than I do. The patches do not last for 3 days for me. I take them every 2 days and try to alternate changing (sets of) patches so that I change one or more patches each day. This means: at a dose of 200 ug/h, use 100 patches. Put on patch A - 100 on day 1; put on B - 100 on day 2. On day 3 replace A with a new patch C - 100. This keeps the dosage more consistent. At 175 it works fine with A-75 and B-100, etc. Variation of temperature can cause withdrawal symptoms for me, which is frustrating. The initial skin irritation was addressed by spraying a corticosteroid inhaler on the skin in the application area, then letting it dry before applying the patch, for the first several months of use. Dental issues are a problem for long-term use, as is constipation. F 34 6 years
125-225 1X O
12/31/2010
 5  L-4,L-5 herniated degenerated discs Any strenuious activity I sweat terribly,stomach distension,flatulance and mood swings. On the 2nd day of three is my best day,the third day Im exhausted. Constipation is chronic and Im a vegatarian.Best of all Opoids ever had in 17 years. As a user of Duragesic 7.5 mcg for more than 6 years,It has totally changed my life for the better. I get Bioclisive Patchs to adhere over the Duragesic so theres no problem for adhedion. I havent gone to the pool since the patch but use a treadmill instead,the problem is mainly this drug makes me sweat terribly and Im fit.Generic sucks. M 49 6 years
6/7/2007
 5  neuropath pain,severe spasms,Fibrom Initially for a few days I was tired, somewhat Skin irritation and minor constipation,& dry mouth, constipation. But all side effects go away after awhile. Best med so far for me. On the 100 mg patch now.But for those of you who have problems with the patch sticking, You can use a cover patch and that keeps the patch from drying up. And you can get them FREE form Johnson and Johnson, and there is a program that will pay for your cost of the patch and it is Duragesic themselves. All you have to do is get your Doctor to fill out a form saying you need it, and for what reason, course they go by the income in the family and how many live in your home. But I'M sure just about anyone can get coverage. Now as far as the nausea goes, I take phenagan for other reason also, but you can take Atarax 25 or 50 mg for nausea and itching and it can help you sleep ask your Doc about this. I have been on the 100 mg for 4 years and we change my patch every 2 days and I do go through break through pain. Some days are better then others, but it just depends on the flair up I'M having. I do take break through medication, If you have question on these programs F 39 5 years
8/2/2006
 5  Continue from above! Initially for a few days I was tired, somewhat Skin irritation and minor constipation,& dry mouth. But all side effects does go away after awhile. If you have question on these programs I mention please email me [email protected] I would be glad to give the numbers to the programs on the coverage's on the cover patches and the drug program to help pay for your Duragesic. But I have realized that no drug can completely take your pain away when you live in severe pain daily. I rely on My Lord to get through those days, and everyday of my life. But this is the best pain relief have had even after 5 or more years. God Bless! F 39 5 years
8/2/2006
 4  Multiple S, Spinalstenosis cerv/lum Very little other than it not working pasr 50hours at any strenght. Requires Breakthrough meds if used for long term or dose is not changed. M 34 5 years
100
4/1/2014
  

DURAGESIC-100  (FENTANYL):  See also Warning section. This medication is used to help relieve sudden (breakthrough) cancer pain in people who are regularly taking moderate to large amounts of opioid pain medication. Fentanyl belongs to a class of drugs known as opioid (narcotic) analgesics. It works in the brain to change how your body feels and responds to pain. This medication should not be used to relieve mild or short-term pain (such as due to headache/migraine, dental procedures, surgery).   FDA Approval Date: 1990-08-07 (Sources: U.S. Centers for Medicare Services, FDA)

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