DURAGESIC-100 Reviews (FENTANYL)

Average Rating: 3.9 (148 Ratings)

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 ANALGESICS, GENERAL    DEA Schedule II   

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DURAGESIC-100  (FENTANYL):  See also Warning section. This medication is used to help relieve sudden (breakthrough) cancer pain in people who are regularly taking moderate to large amounts of opioid pain medication. Fentanyl belongs to a class of drugs known as opioid (narcotic) analgesics. It works in the brain to change how your body feels and responds to pain. This medication should not be used to relieve mild or short-term pain (such as due to headache/migraine, dental procedures, surgery).   FDA Approval Date: 1990-08-07 (Sources: U.S. Centers for Medicare Services, FDA)

  

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More on DURAGESIC-100: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DURAGESIC-100COMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Reflex Sympathic Dystrophy At this point I really don't have any side effects. the exact dose is 275 every 72hrs. The fentanyl patch saved my quality of life, such as it is. I was in excrutiating pain for 2 years while trying all those oxy,,,whatever pills on the market until the patches were introduced to me and finally some relief. The only problem I problem I have with them, honestly, is that over the years I have been titrated up on the dose so much, because the disease I have is a progressive one, that there really is not much further to go without stopping my breathing. And when I need surgery to change the battery in my neuro stimulator, what pain medicine do they give me?? Fentyal is the top of the line. I've been given dillaudid before and it takes the edge off. But that's the problem with this medicine...its fantastic for major and long term pain, but be careful.....there is a limit....I know I've reached mine and now I'm in a predicament and I still have more and more pain, as well as break thru pain. F 47 18 years
275 3X W
2/8/2016
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 5  MCTD Little nausea I'm only taking 50 mcg every 72 hrs. A total life changer for me. I live with chronic pain over my whole body. I've tried MS Contin ER, norco, savella, Butrans, and various NSAIDS. The only medication that has me living a somewhat normal life. F 37 3 weeks
50 mcg
3/4/2015
 5  degenerated disc's Minor itching morning after applying. Occasional night sweats, I think related to time of applying. Never had one remain usable for more than 48 hrs. But, I have a somewhat normal life now, & side effects would have to get much, much worse for me to switch from them. Best pain management I've had, & while I'm not pain free, I am able to lead a functional, productive life, & not spend my days back and forth from sofa to bed trying to find a comfortable position. And, I don't get the "addict" looks from the chemist that came with other chronic pain medication. M 39 3 years
50mcg
6/22/2014
 5  Spinalstenosos,multiple bad discs None I have a life now, F 60 4 years
75
1/21/2014
 5  Herniated disc Flushed face, burning at patch site. The patch has given me pain relief like no other long acting medicine. I've been on OxyContin and MS Contin, fentanyl has worked the best relieving my pain. F 39 1 months
50mcg
10/11/2013
 5  I have chronic RA and vonwilliebran I have suffer with chronic pain since I was little girl due to my RA but my RA got worst know since I got pregnact so my doc put me on the duragesic patch which it has make my life easier, tho I'm concern in many ways me being pregnact and afraid that my baby may come out addicted to it, 2nd not able to sleep sometimes and getting a lot of sweats F 26 3 months
75mcg
3/27/2013
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 5  Spinal Cord Tumor & chronic pain Loss of appetite. Patch for 72 hours only works 48 hours for me. F 57 4 years
100 mcg
11/7/2012
 5  Shattered femur-chronic pain I have had no side effects. F 45 2 years
75
7/29/2012
Email
 5  severe pain disorder after a mva dry mouth, suppressed appetite and nausea side effects are totally worth it. F 41 2 months
37mg 1X day
5/18/2012
 5  spinal fractures, and sciatica The only side effects I noticed were dry mouth, and loss of appetite. The loss of appetite was the worst, but, well worth it for the superior pain control I received without feeling foggy, or high. A LIFE SAVER, AND CHANGER! F 31 2 years
50mcg
1/22/2012
 5  Fractured spine - burst L4 Reduced appetite, occasional insomnia upon initial application, reduced effectiveness upon day 3 of patch life After a 35 foot/5 storey fall upon concrete, I smashed myself up pretty badly and was initially given IV morphine while in hospital (1 month) and then Oxycontin the first 3 months of my 6 month stay at a rehab' centre before moving onto Duragesic 50 mcg, which was a MASSIVE improvement by the 2nd day..best thing the Doc's ever did for me!! I could never expect life to be perfect after smashing myself so terribly but Duragesic is FAR better than any other analgesic I've tried. Over time, I've progressed to 75, and recently 100 mcg as one of the discs has worsened and more pain relief has been required but no increase in side effects!! M 38 3.5 years
100 1X day
1/18/2012
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 5  Generalized internal chronic RSD Nausea, vomiting, tiredness I tried over 60 various medications to control the intense chronic pain caused by my generalized internal chronic RSD (Reflex Sympathetic Dystrophy). Only strong extended release narcotic painkillers work for me. The one that works best for me is Duragesic (brand name fentanyl patches made by Janssen Pharmaceutica). Generic fentanyl patches do not work as well for me, if at all, and cause me much worse side effects. I can say without the shadow of a doubt that Duragesic patches gave me back my life, that is, they gave me a life worth being called a life. Thanks to the Duragesic patches, I can now work. I can also do the activities I enjoy most: sky diving, horseback riding (especially circus type), water skiing, rock climbing, mountain hiking, etc. I can never thank Janssen Pharmaceutica enough for making these wonderful fentanyl patches. The only negative point is the very high cost of the patches, for patients whose medical insurance will not cover fentanyl patches and for uninsured patients. F 37 9 years
125 mcg 1X O
11/25/2011
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 5  Complex Regional Pain Syndrome dry mouth, occasional withdrawal symptoms, fatigue, constipation, initial skin rashes on application site Has the potential to move you from constant intense pain and hopelessness to managed pain levels that are livable. I don't know if it is possible to get to a zero level of pain with it, perhaps because I am resistant to take more than I do. The patches do not last for 3 days for me. I take them every 2 days and try to alternate changing (sets of) patches so that I change one or more patches each day. This means: at a dose of 200 ug/h, use 100 patches. Put on patch A - 100 on day 1; put on B - 100 on day 2. On day 3 replace A with a new patch C - 100. This keeps the dosage more consistent. At 175 it works fine with A-75 and B-100, etc. Variation of temperature can cause withdrawal symptoms for me, which is frustrating. The initial skin irritation was addressed by spraying a corticosteroid inhaler on the skin in the application area, then letting it dry before applying the patch, for the first several months of use. Dental issues are a problem for long-term use, as is constipation. F 34 6 years
125-225 1X O
12/31/2010
 5  Broken back. spinal cysts, CPS Skin irritation (esp. w/ new SANDOZ patches), constipation, occasional mood swings, occasional nausea, slight "loopy" sensation rarely The SANDOZ branded fentanyl patches are now made by ALBA (a division of Johnson & Johnson), and as of March 2009 (the copyright date on the packaging), stopped using a gel reservoir with a porous membrane covering the reservoir in its high-dose patches (by 2010, SANDOZ eliminated gel reservoirs in ALL of its fentanyl patches). Instead, SANDOZ (like competitor Mylan) uses a matrix of Fentanyl in strands that melt with body heat. The matrix is covered with polyacrylate adhesive and backed with a VERY thin polyester/ethyl vinyl acetate covering My body does not react well to these new patches; I get nausea (not uncommon; some studies show that up to 10% of people on ANY high-dose narcotics will develop nausea during product use) and my skin gets so irritated I can watch it pinken through the semi-opaque covering. Pain doc is attempting to reduce my overall fentanyl usage (thus, adding a box of 50 mcg/h in with the regular 75 mcg/h to facilitate switching from high to low). I'm still having great success w/ the patch, though--nothing keeps pain at bay like it. F 47 3 years
50-75 mcg 1X O
10/31/2010
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 5  severe fibromyalgia, rheumatoid art constipation, sweating, weight gain-I take 100 mg every three days. Take tylenol, ibuprofen for breakthrough, it's not that bad. Gave me a life back. Battled pain from severe fibromyalgia, rheumaoid arthritis, 3 herniated discs, lups-I had just about had it with doctors and medications prescribed. I was in so much pain, my quality of life was nil. This gave me my life back, yes, with a few changes, but all I could handle. I did end up having all my teeth extracted and was told the patch was a factor in that but hey, I got dentures and all is well. If you take this drug as directed it is a life save. If you mess with it, it can kill you. A F 59 4 years
100 mg 1X O
6/16/2010
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 5  Chronic pain from nerve damage A little tiredness and I have noticed my memory is not as sharp as it was sometimes-these side effects are NOTHING compared to other narcotic meds I have tried through the yrs and I have tried them all!! This medicine has been a miracle for me and I am amazed that it is not prescribed more often for people who have severe and chronic pain. It is so amazing not to deal w/ the constant withdrawal/ups and downs of oxycontin,vicodin,and other more commonly presribed meds. Morphine gave me terrible migraines and restless legs as it would wear off and it made me sooo tired. These patches give a steady stream of med. that if used properly,prevent you from ever having to deal with all that agony. It also gives me better pain relief than any other med w/o any real side effects besides a little memory issue which could have more to do w/ my insomnia which is unrelated to this med.I have also only had to up my dose once in 4 yrs and that was because my condition worsened not because the drug became less effective. So, talk to your dr. if you have chronic pain....people who have died or od'ed from Fentanyl have misused it - people don't die from using it correctly. F 46 4 years
50mg 1X O
4/6/2010
 5  chronic pain, spinal tumors mild constipation, skin irritation from patch adhesive, mood swings This medication is a lifesaver, literally. I was ready to commit suicide because I could not stop the pain I was having from tumors on my spine and severe fibromyalgia. I was first given it after a car accident, and within an hour after the patch was put on, I felt something I hadn't felt in YEARS: Pain-Free. It's not a perfect drug--it does cause constipation, the adhesive is a skin irritant, and my moods tend to swing up as the medicine gets absorbed and down as the dose runs out--and if you stop taking it suddenly, you WILL go into opiate withdrawal, no question. But if you're a chronic pain sufferer who can't get relief no matter how many high-dose narcotic pills you take, ask your doctor about the fentanyl 3-day patch (the generic name for Duragesic). One patch can change your life...at least, it did for me. F 47 2 years
50 mcg 1X O
3/7/2010
 5  Fibro, herniated discs, neuralgias mild constipation, skin irritation with Duragesic brand when worn above waist This medicine literally saved my life. Before it I was in such severe, constant pain that I was actually seriously considering suicide. I had zero quality of life. This medication allowed me to be functional again and although I am far from being pain-free, my quality of life is pretty good. I am on disability but am able to have a life now. I would highly recommend this medication to anyone with long-term, severe chronic pain not getting relief from other pain meds. I change my patch every 48 hours because on the third day it seemed like the drug was wearing off and I was needing lots of breakthrough pain meds. (Many Medicare Part D plans pay for up to 15 or 16 patches a month so ask your insurance carrier if you have the same issue). I am now on minimal breakthrough pain meds. I have been at the same dose for 6 1/2 years and have been able to avoid increasing the dosage by using alternative therapies along with the patch. I have found that the Mylan brand, being a smaller patch, causes less skin irritation than Duragesic, especially when worn on the very lower back/top of buttock area where less pulling occurs with movement. Although the manufacturer tells you that you should wear it above the waist, this is only because they only studied it there, but I had no decrease in effectiveness wearing it on my lower back or upper buttock area. The patches also stay on much better for me there, with no need for tape or overlays. F 34 7 years
75 mcg 1X O
2/26/2010
 5  spinal pain I forgot to add something on my previous post. I use the Mylan patches. Get "Tegaderm" covers. Nothing can get these off with the Tegaderm. It works 100% in holding them on and intact. 100 showers and they wouldn't come off. F 62 2 months
1/26/2010
 5  C6- C7 T1 spine pain some nausea when first changing and putting on new patches. This has also been a literal lifesaver for me. I also was about at the stage of suicide from intractable pain, ( back, and chest ) for 5 months. If you can imagine how horrible and disconserting it is to have chest pain 24/7 for months, and literally not be able to do for yourself. Oral opiates just were awful, made me sick, didn't last, or just didn't work. At first I was very leery of starting the patch, ( I am an RN ) but it got to a point where I was desperate for relief. Best thing I ever did. It gave me back my life. I have also just had my second cervical epidural with some relief but not enough, unfortunately. F 62 2 months
1/26/2010
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DURAGESIC-100  (FENTANYL):  See also Warning section. This medication is used to help relieve sudden (breakthrough) cancer pain in people who are regularly taking moderate to large amounts of opioid pain medication. Fentanyl belongs to a class of drugs known as opioid (narcotic) analgesics. It works in the brain to change how your body feels and responds to pain. This medication should not be used to relieve mild or short-term pain (such as due to headache/migraine, dental procedures, surgery).   FDA Approval Date: 1990-08-07 (Sources: U.S. Centers for Medicare Services, FDA)

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