DURAGESIC-100 Reviews (FENTANYL)Average Rating: 3.9 (148 Ratings)Filter ResultsCompare DURAGESIC-100 with similar:
Type: Rx Drug
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Results are sorted by Gender males first. Key to Ratings: 1=LOW (I would not recommend taking this medicine.) |
| RATING | REASON | SIDE EFFECTS FOR DURAGESIC-100 | COMMENTS | SEX | AGE | DURATION/ DOSAGE | DATE ADDED |
| 5 | Fractured spine - burst L4 | Reduced appetite, occasional insomnia upon initial application, reduced effectiveness upon day 3 of patch life | After a 35 foot/5 storey fall upon concrete, I smashed myself up pretty badly and was initially given IV morphine while in hospital (1 month) and then Oxycontin the first 3 months of my 6 month stay at a rehab' centre before moving onto Duragesic 50 mcg, which was a MASSIVE improvement by the 2nd day..best thing the Doc's ever did for me!! I could never expect life to be perfect after smashing myself so terribly but Duragesic is FAR better than any other analgesic I've tried. Over time, I've progressed to 75, and recently 100 mcg as one of the discs has worsened and more pain relief has been required but no increase in side effects!! | M | 38 | 3.5 years 100 1X day | 1/18/2012 | 5 | Fibromyalgia--chronic pain | Initially for a few days I was tired, somewhat nauseous, which subsided when lying down. After a few days all side-effects were gone, and I was left with feeling normal for the first time in years. | The patch has been fantastic. There are no ups and downs like with oxycontin; morphine; etc., just steady pain relief. Also, no stomach issues as it passes through the skin. Nice not to have to take pills every x number of hours. I would probably be dead without the patch as it has improved my life immensely. | M | 41 | 2 years | 1/29/2006 | 5 | degenerative disk disease/ lumbar 5 | little bit of stomach upset and dry mouth.this is far better than taking 120 mgs of oxycontin and percocet for breakthroughs like i was for the past 2yrs. now im on the 50mg patch and only have to take a percocet 2 times a day as compared to sometimes 6-8 of them | i recomend this patch if you want pain relief instead of having to take tons of pills. | M | 45 | 2 weeks | 5/8/2006 | 5 | Fibromyalgia--chronic pain | Initially for a few days I was tired, somewhat nauseous, which subsided when lying down. After a few days all side-effects were gone, and I was left with feeling normal for the first time in years. | The patch has been fantastic. There are no ups and downs like with oxycontin; morphine; etc., just steady pain relief. Also, no stomach issues as it passes through the skin. Nice not to have to take pills every x number of hours. I would probably be dead without the patch as it has improved my life immensely. | M | 41 | 2 years | 1/29/2006 | 5 | neuropathic pain | dry mouth, constipation. Also on morphine sulfate, neurontin...so the mix probably does this. Can't sleep at night but feel tired. | Best med so far for me. On the 100mcg patch now. They do not stick as well as I'd like but will stay longer if you hold them on your skin and press for 60+ sec on application | M | 42 | 2 years | 12/15/2005 | 5 | Chronic back pain and severe spasms | Skin irritation and minor constipation | The best pain relief on the market. I have suffered since 1990. With a 50mg patch I'm good for at least 36 hours and supplement with perc. 10/325 on the last day. Does anyone know how to deal with the withdrawals during run out periods? If so I'd appreciate the advice. | M | 34 | 4 months | 12/26/2005 | 5 | low back pain | Very Severe Nausea, Itching, Hiccups, dizziness, sleepiness, anxiety | I only rate this a "5" so most people will read this. The way this site works, viewers only read the good stuff at the top. BE VERY CAREFUL WITH THIS POWERFUL AND DANGEROUS DRUG. All you have to do is see the number of class action law suits against the makers of this patch to realize many people have had severe trouble and even died because these patches are well known to deliver the full 3 days of powereful drug into your system in 12-24 hours. I had widely varying symptoms, even after I thought I was fully acommodated to the drug. A Board Certified Pain Management Physiatrist told me to "TAKE THAT PATCH OFF!!!" based on experience with the poor delivery system and my symptoms. Also apparently the withdrawal effects can be very bad. I switched to Kadian and have MUCH BETTER PAIN RELIEF WITH LESS DRUG, and none of the bad side effects. I think Fentanyl is potentially dangerous and you shouls be suspect of its use. You are in control of your meds, ask your | M | 50 | 3 months | 4/23/2006 | 5 | neuropathy | Some nausea at first, which gradually disappeared, Constipation, which I treat with stool softeners. Some dizziness when standing up. | I have nerve damage in the nerve roots leading from C5-C7 caused by a herniated disk between C3/C4 and multiple stinosis in that same area that was repaired by 6.5 hours of surgery. I also have nerve damage from a stretched brachial plexus branch behind my left shoulder that was caused by the same fall that ruptured the C3/C4 disk. My left ACL joint is compressed causing chronic bursitis as a result of the damaged nerves. I spent 18 months post-surgery trying to treat the pain and inflammation with hydrocodone, steroid shots, Neurontin and Cymbalta. My blood pressure was averaging 160/90 during this period. A cardiology intern mentioned Fentanyl and after trying Neurontin and Cymbalta with terrible side effects, I mentioned it to my GP who agreed that it would be worth a try. My physical functionality is returning and my pain level is now at 1-2 instead of 5-6. This drug has saved my life. I was afraid of the addiction possibilities, so I stopped it for three days to see what would hap | M | 53 | 60 days | 2/8/2007 | 5 | Disc pain and rotatory scoliosis | None that I've noticed. I used it a few years ago when I was obese, and it made me sleep a lot. But now it doesn't. | I used it years ago and started again recently. I believe this is the best long-acting pain reliever that exists. It was one of three options offered to me: Morphine, Oxycontin or Fentanyl. I tried the first two and didn't like them. Fentanyl is wonderful. There's no "high" like oxycontin. No side-effects like morphine. My breakthrough pain med use has gone down remarkably. I have to change patches every 48 hours, as the 72 hour schedule didn't give me enough pain relief or consistent relief. ASK YOUR DOCTOR TO LET YOU TRY THIS. It is WONDERFUL! However, when you go off it you may have to use the Suboxone program. I did years ago and it worked to get me off the 75 mcg. dose I was on at the time. I'm only on 25 mcg now, but I weigh half as much as I did then so I figure that's why less works now. | M | 4 years | 10/16/2008 | 5 | DDD | None | I was on the 50s and now on the 100s. Completly pain free now. I've tried going with the Oxycontin and others but I abused them by taking them by my mood and not just by my pain. | M | 52 | 4 months | 10/10/2006 | 5 | Chonic LBP from HNP x 3 x 8 years | Only N&V at high doses. A little skin irritation. | This is a very potent opiate. The fatal dose is 1.036 mg for a 150 pound person. The patches have between 2.5 and 10.0 mg - many times a fatal dose. It's wise to recognize that you're wearing enough fentanyl to kill several people. So DON'T PLAY WITH THIS DRUG. It's analogs are even more potent, some of them thousands of times more potent, so don't try to alter the gel in any way or allow the patch to get too hot or too cold. If you play around with this drug, you might alter it and turn it into something that will kill you before you even know you're in trouble. At 20ng/mL, someone could crack your chest open and you wouldn't feel it. This was originally used as a surgical anesthetic. Just don't play with it. That said, this is the most effective narcotic I've ever taken (and I've taken just about all of them). It can be very frustrating, trying to get them to stick well, getting them fouled up and ruined. They can't be reapplied once they come off unless you have Tegaderm or Bioclusive. Janssen will ship you either one if you ask. Both of these are adhesives that cover the whole patch. Ask for the Tegaderm. Bioclusive is VERY STICKY and will take off skin when you remove it. The Tegaderm is easier to work with and that makes it less likely you'll get the patch folded up and stuck to itself. Cut the Tegaderm and just cover the edges of the patch. The Duragesic seems to be less effective when it's covered. There are no reinforcing side effects with transdermal fentanyl, so it might not be obvious to you that it's doing anything. There's no euphoria at any dose and no anxiolysis or feeling of relaxation. So be patient and just focus on your pain and whether or not it's better. If it's not, tell your doctor. A higher dose if preferable to changing to something else, in my experience, because I've found nothing that works as well. And I didn't realize how effective the fentanyl was until I changed it to something else. And realizing my mistake, I went back to fentanyl, got frustrated with it again, and changed to something else again. But the pain's back and I'll be changing back to fentanyl next week, God willing. If you have any intellectual curiosity (which by itself means you're smarter than our President) about the history of Duragesic - it's development and clinical trials, read: http://www.vtd.uscourts.gov/Supporting%20Files/Cases/02cv20.pdf Facinating reading. | M | 40 | 5 months | 11/4/2004 | 5 | Sugery | None. | Used in sugery. | M | 23 | 1 days | 11/5/2004 | 5 | REFLEX SYMPATHETIC DYSTROPHY | LOSS OF APPETITE. CONSTIPATION- CONTROLLED WITH SENNA PLUS. | IT IS THE ONLY MEDICATION THAT HAS EASED THE CONSTANT BURNING PAIN. HAVE HAD RSD FOR 14YEARS. WONDERFUL DOCTOR STARTED ME ON FENTANYL IV THEN CONVERTED TO DURAGESIC PATCH. CONTINOUS USE FOR 15 MONTHS NOW(75 UGH). WILL NOT STOP FOR ANY REASON NOW. THE RELIEF IS JUST GREAT. | M | 58 | 15 months | 8/28/2004 | 5 | RSD | I have no side effects. | The Duragesic patches are wonderful. My dose is 150 ugh every 72 hours. I would like to thank Janssen Pharmaceutical for coming up with the pain patch. They are a little pricey the 100 ugh are $625.00 and the 50 ugh are $310.00 but it is well worth it. | M | 49 | 2 years | 9/2/2004 | 5 | disabling low back pain | rash under patch (sometimes).increase in libido. NO cash in wallet!!! | I use 175mcg/hr ev 48 hrs. I did not notice any releive until multiple patches were used. | M | 40 | 2.5 years | 2/17/2004 | 5 | chronic neurological pain | For first few days, I had some nausea. Some degree of constipation on ongoing basis. | I initially started with 25mg patch, but over course of six months, did not receive the relief of pain that I expected, namely to get my pain to the point that it was only really bad one or two days a week. Subsequently, I've begun using 2x25mg patches. I've found this works better than 1x50mg patch, as there seems to be variability between patches. When I was using a single patch, sometimes the pain relief would go away before the 3-day use was completed. On other ocassions, pain relief would still be adequate after 3 days. I blame this on patch variability rather than my normally-variable rates of pain because of the constipation issue -- namely, when the patch quits working, my stool gets looser. However, overall, Duragesic, despite its high cost, is significantly better than pain meds I've used in the past, which have not been satisfactory. Previous medications included stadol and vicodin, with their attendant cycles of on-oagain/off-again relief and the | M | 59 | 10 months | 2/7/2004 | 5 | numerous orthopedic injuries | constipation,easily remedied,no other effects | I had a delay in getting a refill because insurance would no longer pay,the physical withdrawals were real nasty.But I guess that is true with all narcotic meds. | M | 48 | 3 months | 1/6/2005 | 5 | complete degeneration of lumbar spi | constipation | M | 51 | 2 years | 1/17/2005 | 5 | Multi Level Lumbar Discogenic Pain | Sedation, very mild constipation, dizziness, minor short term memory problems, dry mouth |
I'm 23 and have had constant lower back pain for over 2 years. When I say "constant" I do mean "constant". I don't think I can stress that enough. I don't mean "constant" as in "it hurts only sometimes, but it hurts everyday." I mean that once it started, it never stopped or let up. Not one hour, not one minute, not one second, not one instant. I was not able to stay in school or hold a job. Everyday I wanted to kill myself. I spent a little over a year going to doctors: 2 GP's, an
internist, 2 orthopedic surgeons, 2 rheumatologists(one
at the University of Alabama Medical Center at About 8 months into this long quest, I changed my family doctor due to insurance reasons. This doctor wrote me a scrip for 45 hydrocodone 10/500’s. This was the first time I was able to get ANY relief and any meaningful sleep. Almost as importantly, I felt like someone finally believed me. That Dr. moved me to 7.5’s after about 2 weeks of the 5’s
being ineffective, and he changed the quantity to 60 per month. About that time
he referred me to a pain clinic. I went there and went through numerous tests.
More X-rays of course, another CT scan, a Bone Scan, several steroid and other
injections to test for facet joint problems and such things. Throughout all
this my pain doctor was still only writing the 60 7.5/500 hydros
that my GP had. I stayed on this for probably 6 months or so. It gave me about 30-40% relief. I changed pain doctors, again for insurance reasons, and also was referred to Johns Hopkins. Based on all my records and my severe constipation, they recommended that my Dr. put me on Duragesic. I started on the 75ug/hr patches. The pain relief on the 2nd day was breathtaking. I had entered a new world, a new life. However, the side effects were terrible: severe sedation, almost passing out when I closed my eyes, not being able to focus my eyes. So the following day I had my Dr. move me down to the 50ug/hr patches. It has been 15 days since then; I went in to get my refill
today and asked to move back to the 75’s, as the pain relief with the 50’s was
not quite what I’d hoped. It’s now | M | 24 | 28 days | 3/2/2005 | 5 | severe peripheral neuropathy | None | M | 50 | 2.5 years | 3/7/2005 |
DURAGESIC-100 (FENTANYL): See also Warning section. This medication is used to help relieve sudden (breakthrough) cancer pain in people who are regularly taking moderate to large amounts of opioid pain medication. Fentanyl belongs to a class of drugs known as opioid (narcotic) analgesics. It works in the brain to change how your body feels and responds to pain. This medication should not be used to relieve mild or short-term pain (such as due to headache/migraine, dental procedures, surgery). FDA Approval Date: 1990-08-07 (Sources: U.S. Centers for Medicare Services, FDA)