DURAGESIC-100 Reviews (FENTANYL)

Average Rating: 3.9 (148 Ratings)

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 ANALGESICS, GENERAL    DEA Schedule II   

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DURAGESIC-100  (FENTANYL):  See also Warning section. This medication is used to help relieve sudden (breakthrough) cancer pain in people who are regularly taking moderate to large amounts of opioid pain medication. Fentanyl belongs to a class of drugs known as opioid (narcotic) analgesics. It works in the brain to change how your body feels and responds to pain. This medication should not be used to relieve mild or short-term pain (such as due to headache/migraine, dental procedures, surgery).   FDA Approval Date: 1990-08-07 (Sources: U.S. Centers for Medicare Services, FDA)

  

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More on DURAGESIC-100: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DURAGESIC-100COMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  chronic pain psychotic episodes My grandmother was prescribed this medicine for pain. She is elderly but her mind has always been very sharp. Shortly after taking this her speech was slurred and she forgot who and where she was. She said very strange things and became very scared. It was scary for all of us. It was obviously the medicine that did this to her. The only way I know to describe it is she had psychotic outbursts. F 86 2 weeks
11/18/2005
 4  Severe Neuropathic Pain/Joint Disea The first side effect was sleepiness and then constipation which has not gone away. The initial dry mouth, however, passed after a few days. Duragesic is a life saver. I was literally at my wit's end and cried from pain every day, no physical treatment or medical treatment (Vicadin, Neurontin, Percocet) gave enough relief so I could still function somewhat. Duragesic works straight through, although some days I feel better than others, but still considerably improved. I have been taking it under the supervision of a Pain Management Specialist along with my first of three epidural lumbar medial nerve injections. F 64 12 days
6/28/2004
 3   BACK PAIN M 64 30 days
8/2/2005
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 4  atypical facial pain vomiting when starting or going to a higher dose.used visteral with good results.severe sweating and had 20lb weight loss after 4 mos. Medication does seem to wear off after 2 days and I have to take Vicodin for the breakthru pain which doesn't help much. But at least I'm not damaging my liver as I was with the Vicodin/Tylenol that I was taking every 3-4 hrs. The patch does not stick well at all and it should for the price we have to pay. I put the patch on then spread tincture of benzoin around the patch with a q-tip then apply tegaderm to cover it all. Just an old nurse's trick. Works very well but the tegaderm is also very expensive. I still am very happy to have good pain relief. F 63 4 days
1/12/2005
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 3  pain none F 63 15 days
7/23/2008
 5  Chromnic pain after multiple spine The only side effect I have had is mild constipation which resolved itself once I added more fiber at breakfast. The Duragesic Patches are truly worth their weight in gold IF the Doctor who puts you on it increases the dose until the pain is mostly resolved. I do on occasion take break-through pain medication,Dilaudid, which is inexpensive. The lower the doseage you can deal with on the patches the better off you are as the longer you are on them you do build up to a tolerance to the drug. I have been on Duragesic Patches for nine years and am still only at 150ugh. Three hundred is the maximun dose but you definitely want to save those higher doses for critical life threatening complications down the road, ie. cancer. Duragesic Patches did not work for pain control after surgery for me and methdone had to be used, then down-graded to morphine and finally the Fentinal after the severe pain had resolved. If you are not getting good coverage in the hospital after surgery because the nurses cut back on your meds without the Doctors approval when you still need heavy pain control call in the pain doctors who work at the hospital, some nurses are relentless at not caring about your comfort level. It's dufficult being a chronic pain patient physically. Keep your resolve strong, your mind focused, and strive for a better life in the future. F 62 9 years
10/22/2004
 5  Severe Spinal Pain/Fibromyalgia See note below The only comments I wanted to add regarding the Durgesic Patches are: 1. Duragesic Patches have given me the power to lead a somewhat normal life when my last three spine surgeries failed to give me any permanent relief and the pain became intolerable. 2. The ONLY MAJOR downside to the Duragesic Patches is the cost which is prohibitive when one does not have insurance coverage. This is tragic because some people who desperately need the Patches are totally out of luck. It is a drug that you can not just stop taking you must be weaned off of it and withdrawal is doable but very difficult. We chronic pain patients need to have to have some plan we can fall back on if we have lost jobs or insurance. No human deserves to suffer horribly just because they don't have the money to pay for this drug. PLEASE NOTE: If you are over 55 you can get a discount at K-Mart on the Patches which makes a huge difference. Remember it is not just the drug company which causess the price of the patches to be so high/ F 62 9 years
10/22/2004
 5  Post-Herpetic Neuralgia Early: dizziness, nausea, sweating,constipation, difficulty starting urination. Now: Constipation, difficulty starting urination. Duragesic (100 mcg) is wonderful! I have some breakthrough pain but, mostly, Duragesic helps tremendously. I take a stool softener and wait until my bladder is quite full and those side effects present no problems. I use the Bioclusive dressing to keep the patch on and it works brilliantly! Change patch every 72 hours...no problems. After over 2 years of unremitting pain, I was suicidal so Duragesic, literally, saved my life. F 62 2 years
8/4/2006
 5  spinal pain I forgot to add something on my previous post. I use the Mylan patches. Get "Tegaderm" covers. Nothing can get these off with the Tegaderm. It works 100% in holding them on and intact. 100 showers and they wouldn't come off. F 62 2 months
1/26/2010
 5  C6- C7 T1 spine pain some nausea when first changing and putting on new patches. This has also been a literal lifesaver for me. I also was about at the stage of suicide from intractable pain, ( back, and chest ) for 5 months. If you can imagine how horrible and disconserting it is to have chest pain 24/7 for months, and literally not be able to do for yourself. Oral opiates just were awful, made me sick, didn't last, or just didn't work. At first I was very leery of starting the patch, ( I am an RN ) but it got to a point where I was desperate for relief. Best thing I ever did. It gave me back my life. I have also just had my second cervical epidural with some relief but not enough, unfortunately. F 62 2 months
1/26/2010
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 1  Back pain following back surgery I was prescribed a 50mgs Fentanyl patch. I had placed my first Fentanyl patch on my back on Friday, July 12, 2013 and placed my second patch on a different area of my back on Monday, July 15, 2013. The first 3 days of usage caused me to become very tired and to have much increased pain, not only in my lower back, (sacroiliac area), but, also in my shoulders, neck and upper back. Additionally, I developed severe constipation. (At the time of this writing, Wednesday, July 17, 2013 shortly after midnight, I have not had a bowel movement for four days, despite having used stool softeners). My second patch resulted in my falling asleep at my computer; sleeping with my head on my computer (laptop) from 7:45am to 6:30pm, Tuesday, July 16, 2013 and waking up with acute edema and excruciating pain. I kept waking up and then nodding off, (with my head falling onto my laptop). I became unconscious, disoriented to time, and incoherent. I was, as well, off-balanced and exceptionally woozy! A friend stopped over just when I needed for someone to help me. His coming over was incredibly fortuitous. He had a very difficult time waking me, with my continuing to nod off with my head lying on my computer. He left after both us believed that I was fully conscious. I wasn't. I kept nodding off, repeatedly, finding myself with an unlit cigarette in my hand. I, in time, woke up enough to be able to call my insurance company's 24-Hour "Call a Nurse". We agreed that I needed to call my pain management doctor. He was reached by his answering service. The answering service relayed information from my pain management doctor to me. I was informed to, immediately, remove the patch. I did so. I, at this time, (almost 12:30am, Wednesday, July 17, 2013), am becoming more alert and oriented. I still am having pain; but, the severity is decreasing. I remain very tired and shall, soon, go to bed. This is PRECISELY what happened for me when I was in a SNF and had been prescribed a 50mg Fentanyl patch. The poor nurse who found me in an unconscious state was very frightened telling me, a day later, that I could have died. The insurance company RN told me the same thing and said that I was very lucky to have had my friend come over at the time that he did. I call him, "my angel". Maybe he really is! I have got to inform every doctor with whom I am presently working, (and all future doctors), that I simply cannot take any opiate/opioid medication. Phew! SCARY! F 61 6 days
1X O
7/17/2013
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 5  Spinalstenosos,multiple bad discs None I have a life now, F 60 4 years
75
1/21/2014
 5  chronic neurological pain For first few days, I had some nausea. Some degree of constipation on ongoing basis. I initially started with 25mg patch, but over course of six months, did not receive the relief of pain that I expected, namely to get my pain to the point that it was only really bad one or two days a week. Subsequently, I've begun using 2x25mg patches. I've found this works better than 1x50mg patch, as there seems to be variability between patches. When I was using a single patch, sometimes the pain relief would go away before the 3-day use was completed. On other ocassions, pain relief would still be adequate after 3 days. I blame this on patch variability rather than my normally-variable rates of pain because of the constipation issue -- namely, when the patch quits working, my stool gets looser. However, overall, Duragesic, despite its high cost, is significantly better than pain meds I've used in the past, which have not been satisfactory. Previous medications included stadol and vicodin, with their attendant cycles of on-oagain/off-again relief and the M 59 10 months
2/7/2004
 5  severe fibromyalgia, rheumatoid art constipation, sweating, weight gain-I take 100 mg every three days. Take tylenol, ibuprofen for breakthrough, it's not that bad. Gave me a life back. Battled pain from severe fibromyalgia, rheumaoid arthritis, 3 herniated discs, lups-I had just about had it with doctors and medications prescribed. I was in so much pain, my quality of life was nil. This gave me my life back, yes, with a few changes, but all I could handle. I did end up having all my teeth extracted and was told the patch was a factor in that but hey, I got dentures and all is well. If you take this drug as directed it is a life save. If you mess with it, it can kill you. A F 59 4 years
100 mg 1X O
6/16/2010
Email
 4  Failed back surgeries I also am suffering from severe nerve pain and have been given methadone for that. Duragesic is the only medication that works for me and I like it due in part to a past addiction to codeine. With a patch and the fear of ODing on Duragesic it is the best method for me. I change patches every 48hrs and I have now been on the 75mgc for so long on the second day I am feeling withdrawal symptoms of constant tiredness. M 59 7 years
75mg 1X day
8/7/2011
Email
 4  Back pain, rib cage nerve damage Slightly spacey feeling on 100mcg patch,but just about cut all my pain. Cut back to 75mcg and I think clearly now but some pain has returned. I was on morphine sulfate for a couple of years, total of 90mg a day. This did little to help, made me a little nauseous. Doc switch me to duragesic patch starting at 50 mcg for 6 days then to 100mcg. The 100mcg along with 15mg morphine sulfate for break through pain. This got rid of 80% of pain and did not even need morphine. Two weeks ago I cut back to 75mcg patch, I could not think clearly. Ok on 75mcg although I'm getting about 50% reduction in pain. M 59 3 months
1X O
5/4/2010
 5  REFLEX SYMPATHETIC DYSTROPHY LOSS OF APPETITE. CONSTIPATION- CONTROLLED WITH SENNA PLUS. IT IS THE ONLY MEDICATION THAT HAS EASED THE CONSTANT BURNING PAIN. HAVE HAD RSD FOR 14YEARS. WONDERFUL DOCTOR STARTED ME ON FENTANYL IV THEN CONVERTED TO DURAGESIC PATCH. CONTINOUS USE FOR 15 MONTHS NOW(75 UGH). WILL NOT STOP FOR ANY REASON NOW. THE RELIEF IS JUST GREAT. M 58 15 months
8/28/2004
 3  Degenerative Spinal Disese Constipation, dry mouth, loss of appetite, sleeplessness All I can deal with because of the moderate pain relief I am currently getting. Wondering if I could get more with higher does? I have had 5 spinal surgeries, and one neck surgery over the past 2 years (02-04). Have been playing with pain control since 2004. Pain has/is still way out of control 9+. It seems as if we are simply playing with medication for the breakthrough pain. I have taken Morphine Im-Rel; Morphine Sulfate; Methadone; Avenza; Kadain, Panlor C. MS Contin; Oxycodone Hydrocloride, Loratab. I have also had a dorssal Spinal Stimulator implanted for the left and Right sides. I also have dropped foot on the left side. M 58 6 months
6/12/2005
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 3  Fibromyalgia.and back Now after7 years on fentanyl ive noticed it makes me hurt more.anyone else having this problem.it was a miracle.at first. At first it helped me 100%.not anylonger.it makes me now hurt worse. F 58 7 years
100 mcg
6/23/2017
Email
 3  Failed spinal fusion in neck Trouble with sleep on day one, reduced effect day 1 and day 3, rash and skin irritation when applied to torso. when it's working it works well...some patches don't stick as well as others, no rash when used on biceps M 58 60 days
37.5 10X M
1/24/2021
  

DURAGESIC-100  (FENTANYL):  See also Warning section. This medication is used to help relieve sudden (breakthrough) cancer pain in people who are regularly taking moderate to large amounts of opioid pain medication. Fentanyl belongs to a class of drugs known as opioid (narcotic) analgesics. It works in the brain to change how your body feels and responds to pain. This medication should not be used to relieve mild or short-term pain (such as due to headache/migraine, dental procedures, surgery).   FDA Approval Date: 1990-08-07 (Sources: U.S. Centers for Medicare Services, FDA)

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