PRILOSEC Reviews (OMEPRAZOLE)

Average Rating: 1.9 (1667 Ratings)

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 DISORDERS, ACID PEPTIC

 Type: Rx Drug

  

PRILOSEC  (OMEPRAZOLE):  Omeprazole is used to treat certain stomach and esophagus problems (such as acid reflux, ulcers). It works by decreasing the amount of acid your stomach makes. It relieves symptoms such as heartburn, difficulty swallowing, and persistent cough. This medication helps heal acid damage to the stomach and esophagus, helps prevent ulcers, and may help prevent cancer of the esophagus. Omeprazole belongs to a class of drugs known as proton pump inhibitors (PPIs).   FDA Approval Date: 1998-01-15 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by length of time drug was taken from shortest to longest duration (reviews with no time reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PRILOSEC: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PRILOSECCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  Acid reflux/ GERD All over muscle twitching, stiff neck, sore joints, tingly hands. However it has helped alot with the reflux/gerd. I like that it works but dislike the side effects. F 26 7 days
20mg 2xday
12/6/2011
Email
 2  ulcer felt awful taking it, weakness flu like symptoms, could hardly functionl, went off of it aftr 7days of being ill. better to check into alternatives, while most of these meds are poisonous, others might be less toxic and more effective. F 63 7 days
15 1X day
3/10/2011
Email
 2  acid reflux Large hives. It helped with the acid reflux but I now have large hives all over my body. I could not figure out why I had them as I had not eaten anything different lately then saw that hives is a rare but possible side effect. F 61 7 days
20.6 mg 1X day
4/18/2012
 2  Chronic stomach upset, pain Numbness in fingers and feet, weakness in legs, twitching in face and lips, anxiety, heart palpitations, mental dysfunction I began taking the generic Omeprazole in an attempt to control the stomach upset which was possibly generated by post nasal drip secretions. Strange effects began immediately. First, I noticed a weakness in my legs, particularly my right, while descending stairs. This later became constant, with the bottom of my right foot going nearly numb, becoming tingly. Fingers and thumb on my right hand began to exhibit similar properties. Fingers on my left hand followed. I began to become very concerned as time went on and these problems continued and intensified. I began to think I had a neurological condition, such as multiple sclerosis. I was informed by a friend (nurse) that these might be a side-effects of Prilosec and began to research this, finally stumbling upon this site. I ceased ingestion of omeprazole about 35 hours ago. These were the most unbelievable side effects I've ever experienced. They are thankfully decreasing in intensity and I hope to be (neurologically) back to normal soon. Concluding that omeprazole is a converted Soviet nerve agent. Advise against administration/ingestion. M 31 7 days
20mg 1X day
10/11/2010
Email
 2  suspected GERD extreme bloating(i felt like my stomach was going to explode nearly all day every day was worse in the mornings) extreme nausea(to the point i couldnt really eat or walk much) adbominal pain and cramps,tiredness(i had to lie down most days while on it as i could barely walk),depression and stress, tight throat, tight muscles in shoulders and arms,tingling in arms,dizziness,loss of appetite,strange feelings(i woke up and felt like i was dead sort of out of my body) made me think i was going to die and so was my family,made me moody and i couldnt cope with anything.bit of eyesight blurring,diarrheoa, excessives wind, my stomach gurgled and was in pain the whole time. I went to the docs after suffering a period of extreme stress and anxeity since October 2009, things got on top of me and 4 weeks ago i woke up in night thinking i was choking only to dicover a lump feeling in my throat, i panicked and made it worse, after several visits to different docs who told me it was laryngitis,stress etc another doc examined me thoroughly and said it was a virus but stress has made it worse and possible acid reflux has hurt my throat. So he prescribed me Omperazole 20mg once a day which i took last Wednesday.....i have never felt so ill in my life, i have had to have my mum over to do the house work as my partner is too tired from work and i was not able to do a thing, both were worried as i refused food and started getting more depressed, all i could think was i didnt want to be alone and that i was dying, it was terrible....so both partner and mum said stop the pills so i did on Tuesday this week after 7 days....i am still ill but slowly getting there....the tiredness is better, but stomach cramps are here with a vengance and i had a bout of acid diarrheoa last night which is still with me this morning. My general feelings is a bit uplifted but it is difficult to feel happy when you are running to toilet and your stomach is crippling you. I was wondering how long i am expected to wait to feel a lot better... my appetite is slowly returning and the bloating is not as bad, am taking my usual Peptac suspension. Please feel free to email me with any F 28 7 days
20mg 1X day
2/28/2010
 2  Barret's Excessive sweating, anxiety, and pain in stomach, hard to swallow. I already have been diagnosed with major depression, so it is hard to say if this has been making my condition worse.I feel like I am hot flashes all over again.I was suppose to take this medication back in Jan., but I figured I didn't have any stomach problems. After talking to my internist, he suggested that I had to take this because my Barrett's could lead to cancer of the esophagus. I am going to try this medication for one more week and if I feel better, I won't contact my gastro dr.I also thought that I was going crazy, because night and day sweats are not listed as a side effect. This site is extremely helpful. F 56 7 days
40 1X day
4/20/2010
 2  HEARTBURN Diarrhea, very severe. Started about 3 days into it. Goes away when I quit taking Prilosec - comes back within a couple of hours of restarting regardless of what I have eaten and even if I have eaten nothing at all. No anxiety but more dreams and harder to go back to sleep if I wake. Tired of having to keep the bathroom in sight. I'll probably go back to popping Rolaids if this keeps up. My Dr wants me to keep taking Prilosec for a week or two to see if the side effects go away. No lessening of the diarrhea yet as of day 7. Definitely cures the heartburn. M 51 7 days
8/19/2006
Email
 2  GERDS, Heartburn Tiredness/ dizziness, depression, bored, stomach pains, headache I'm so glad I found this site. I've been taken this for 7 days and feel awefull. Heartburn didn't really go away. I think I'm going to stop taking this a try something else. M 30 7 days
9/26/2007
 2  ulcer Severe depression, stoned out of it feeling, confused, and fatigued I started taking prilosec only a couple days ago after protonix which gave me severe abdominal pain and shortness of breathe and prevacid gave me really bad pins and needs feeling that hurt. Once started on prilosec i started becoming severely depressed about everything, was almost to the point where i was gonna check myself in a hospital. Did not know it had effect until i found the results in here. Why do antacids mess you up so much if it just a acid reducer??? M 24 7 days
11/29/2008
Email
 2  dyspepsia Headache all day everyday, chest pains, achiness in neck and head, very tired, sore throat, dry cough, shortness of breath seemed to help with my stomach problems but think maybe they'd be better than the side effects of prilosec. plan on asking doc to switch to something else F 28 7 days
7/26/2008
 2  gastritis and heartburn severe constipation (never have had a problem before), headache, fatigue, loss of appetite/feeling of fullness, very thirsty, weakness, slight dizziness helped the gastritis but the side effects and the pain from constipation made it not worth taking F 22 7 days
7/15/2009
 2  nausea and vomitting extended time horrible chest pains and pain between shoulder blades, swollen face and fingers, lots of anxiety I just got on here to read up on prilosec and am going to stop taking it immediately F 36 7 days
12/10/2009
Email
 1  Acid Reflux Severe nausea, vertigo, shortness of breath, gnawing pain in middle upper abdomen, diarrhea, hot and cold sweats, gas and bloating. I started taking the generic brand of prilosec and started feeling terrible right away. I thought it was just my acid reflux seeing how I was just diangosed two days before starting the Prilosec. I stopped for a few days and still felt sick but not as sick as I did when I was taking it. I started again just for a day and I thought I was going to die. My husband freaked out and begged me to go to the hospital. I will never ever take this med ever again!!! F 26 7 days
11/24/2009
Email
 1  Acid Reflux Increased indigestion and gas pain Blurred vision Bloop Pressure spikes Anxiety Choking sensation Stiff Neck Difficulty swallowing Night Tremors I'm going back to Zantac, this drug is a nightmare! F 60 7 days
40 1X day
2/18/2016
 1  Omeprazole MILD ACID REFLUX AFTER A BURNING VEINS AND LEGS ACHING JOINTS ANXIETY SUICIDAL; THOUGHTS FATIGUE BLOOD PRESSURE ROCKETED BUT HAS NOW GONE BACK TO NORMAL FELT LIKE I WAS GOING TO DIE I HAVE NOW BEEN OFF THE DRUG FOR 5 MONTHS BUT AM STILL GETTING BURNING PAINS IN MY LEGS AND SHOULDERS EVERY DAY THE ANXIETY HAS NOW GONE AWAY BUT I STILL FEEL VERY FRIGHTENED THAT THIS HAS DAMAGED MY BODY PERMINANTLY I HAVE NEVER SUFFERED FROM JOINT PAIN BEFORE AND THE PAIN IS JUST AWFUL AND MAKES ME FEEL VERY MORBID I AM WONDERING IF IT WILL EVER GO MY VEINS SWELLED UPAT FIRST BUT NOW HAVE GONE DOWN A LITTLE I FEEL AS IFMY WHOLE SYSTEM HAS BEEN POISONED HAD VERY DRYMOUTH AFTER ABOUT A MONTH OF COMING OFF THE DRUG BUT THAT TOO SEEMS A BIT BETTER NOW BUT I STILL HAVE A HORRID WHITE COATED TONGUE THIS DRUG SHOULD NEVER BE ALOUD ON THE MARKET AS TO SOME PEOPLE IT IS PURE POISON IT CERTAINLY HAS PUT ME OFF TAKING ANY PRESCRIBED MEDICATION AGAIN I AM TERRIFIED WHAT IT MAY DO TO ME F 62 7 days
1x40mg 2X day
10/23/2015
 1   The side effects from this drug were horrible! I had constant tension or pounding headaches, insomnia, nausea, diarrhea. Awful! Do not take!!! F 36 7 days
9/30/2015
 1  acid reflux Mild diarrhea and stomach pain every day. Twice, the stomach pain got so bad that I threw up. Will be seeking an alternative medicine. F 23 7 days
20 mg
7/23/2015
 1  Feel things in throat/Acid Reflux It appears the med is effective on cutting down acid reflux. However, it had awful side effects on me. First, I had headache. Then, I experienced body aches, insomnia, nightmares, anxiety, irritability, stomach pain, extreme thirst and dry mouth and fatigue. Take it with caution/watch your side effect M 59 7 days
40 mg 1X day
8/22/2015
Email
 1  Acid reflux Anxiety worse than benzo withdrawal.stomach ache Damon secret mind bender F 58 7 days
40mg 1X day
3/4/2017
 1  gastric reflux Anxiety, racing heart, feeling of dread, chest pain, numbness in feet, increased stomach acid, insomnia Dr. prescribed because they thought an issue I had was being caused by gastric reflux (which I now think probably wasn't). Ended up at ER twice and getting an endoscopy thinking I was dying of a heart attack or cancer for what was probably just some sort of sinus issue. My head just got clear enough to figure this all out after only a week on the med. Starting to wean off tomorrow and I feel like it's going to be rough. F 53 7 days
20 mg 2X day
5/23/2020

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